HerbIQ Reference Library  /  Compound Monographs

Active Compound Monographs

Dedicated technical dossiers detailing the molecular profile and evidence weight of individual plant bioactives

Where the Active Compound Index provides a high-level master matrix of the plant kingdom, these Compound Monographs serve as our definitive, independent deep dives. Each entry functions as a standalone scientific reference record—drilling past the surface to map out exact chemical identities, verified CAS numbers, and botanical source biologies with strict clinical objectivity.

Built specifically for product formulators, R&D teams, and researchers, this compendium translates raw plant chemistry into actionable data. Explore the individual monographs below to examine the detailed molecular structures and honest empirical data powering high-performance botanical nutrition.

HerbIQ - Compounds

Phloretin (Dihydrochalcone · GLUT Inhibitor · Antioxidant · Skin)

Compound Phloretin (2′,4,4′,6′-Tetrahydroxydihydrochalcone; Phloretin; Apple Chalcone Aglycone) Chemical class Polyphenol — Dihydrochalcone (chalcone with alpha-beta double bond hydrogenated; unique to Malus and Pyrus species) CAS 60-82-2 Primary source Malus domestica...

Phloretin (Dihydrochalcone · GLUT Inhibitor · Antioxidant · Skin)

Compound Phloretin (2′,4,4′,6′-Tetrahydroxydihydrochalcone; Phloretin; Apple Chalcone Aglycone) Chemical class Polyphenol — Dihydrochalcone (chalcone with alpha-beta double bond hydrogenated; unique to Malus and Pyrus species) CAS 60-82-2 Primary source Malus domestica...

Butein (Chalcone · Anti-inflammatory · Antiproliferative · Antifibrotic)

Compound Butein (3,4,2′,4′-Tetrahydroxychalcone; 2′,3,4,4′-Tetrahydroxychalcone; Butin chalcone) Chemical class Polyphenol — Chalcone (catechol B-ring + resorcinol A-ring chalcone; structurally related to isoliquiritigenin with additional 3-OH) CAS 487-52-5 Primary source Butea monosperma...

Butein (Chalcone · Anti-inflammatory · Antiproliferative · Antifibrotic)

Compound Butein (3,4,2′,4′-Tetrahydroxychalcone; 2′,3,4,4′-Tetrahydroxychalcone; Butin chalcone) Chemical class Polyphenol — Chalcone (catechol B-ring + resorcinol A-ring chalcone; structurally related to isoliquiritigenin with additional 3-OH) CAS 487-52-5 Primary source Butea monosperma...

Isoliquiritigenin (Chalcone · Antioxidant · Antidepressant-like · Anti-tumour)

Compound Isoliquiritigenin (4,2′,4′-Trihydroxychalcone; Chalconaringenin-related; Licorice chalcone) Chemical class Polyphenol — Chalcone (open-chain flavonoid precursor; alpha,beta-unsaturated ketone; licorice characteristic) CAS 961-29-5 Primary source Glycyrrhiza glabra (licorice root), Glycyrrhiza uralensis, Glycyrrhiza inflata...

Isoliquiritigenin (Chalcone · Antioxidant · Antidepressant-like · Anti-tumour)

Compound Isoliquiritigenin (4,2′,4′-Trihydroxychalcone; Chalconaringenin-related; Licorice chalcone) Chemical class Polyphenol — Chalcone (open-chain flavonoid precursor; alpha,beta-unsaturated ketone; licorice characteristic) CAS 961-29-5 Primary source Glycyrrhiza glabra (licorice root), Glycyrrhiza uralensis, Glycyrrhiza inflata...

8-Prenylnaringenin (8-PN · Most Potent Dietary Phytoestrogen · Hops)

Compound 8-Prenylnaringenin (8-PN; 5,7,4′-Trihydroxy-8-prenylflavanone; (S)-8-Prenylnaringenin) Chemical class Polyphenol — Prenylated Flavanone (naringenin with C5 dimethylallyl group at C-8; highest ERalpha affinity of any dietary compound) CAS 53846-50-7 Primary source Humulus...

8-Prenylnaringenin (8-PN · Most Potent Dietary Phytoestrogen · Hops)

Compound 8-Prenylnaringenin (8-PN; 5,7,4′-Trihydroxy-8-prenylflavanone; (S)-8-Prenylnaringenin) Chemical class Polyphenol — Prenylated Flavanone (naringenin with C5 dimethylallyl group at C-8; highest ERalpha affinity of any dietary compound) CAS 53846-50-7 Primary source Humulus...

Xanthohumol (Prenylated Chalcone · Metabolic · Anticancer Research)

Compound Xanthohumol (XN; 2′,4,4′,6′-Tetrahydroxy-3′-prenylchalcone; Chalconaringenin 6′-methyl ether prenylated) Chemical class Polyphenol — Prenylated Chalcone (open-chain flavonoid precursor with C5 prenyl group; hops-specific) CAS 6754-58-1 Primary source Humulus lupulus (hops —...

Xanthohumol (Prenylated Chalcone · Metabolic · Anticancer Research)

Compound Xanthohumol (XN; 2′,4,4′,6′-Tetrahydroxy-3′-prenylchalcone; Chalconaringenin 6′-methyl ether prenylated) Chemical class Polyphenol — Prenylated Chalcone (open-chain flavonoid precursor with C5 prenyl group; hops-specific) CAS 6754-58-1 Primary source Humulus lupulus (hops —...

Wedelolactone (Coumestan · Hepatoprotective · NF-κB Inhibitor · Bhringraj)

Compound Wedelolactone (1,8,9-Trihydroxy-3-methoxy-6H-[1]benzofuro[3,2-c]chromen-6-one; 3-Methoxycoumestrol) Chemical class Polyphenol — Coumestan (3-methoxycoumestrol; benzofuranone-fused chromene; primary Eclipta coumestan) CAS 524-12-9 Primary source Eclipta prostrata / Eclipta alba (Bhringraj), Wedelia calendulacea, Wedelia trilobata Key...

Wedelolactone (Coumestan · Hepatoprotective · NF-κB Inhibitor · Bhringraj)

Compound Wedelolactone (1,8,9-Trihydroxy-3-methoxy-6H-[1]benzofuro[3,2-c]chromen-6-one; 3-Methoxycoumestrol) Chemical class Polyphenol — Coumestan (3-methoxycoumestrol; benzofuranone-fused chromene; primary Eclipta coumestan) CAS 524-12-9 Primary source Eclipta prostrata / Eclipta alba (Bhringraj), Wedelia calendulacea, Wedelia trilobata Key...

Coumestrol (Coumestan · Most Potent Plant Phytoestrogen · Bone Density)

Compound Coumestrol (3,9-Dihydroxy-6H-[1]benzofuro[3,2-c]chromen-6-one; Coumestane prototype) Chemical class Polyphenol — Coumestan (benzofuranone-fused chromene; biosynthetically related to isoflavones via 2-hydroxyisoflavanone oxidation) CAS 479-13-0 Primary source Medicago sativa (alfalfa sprouts), Trifolium pratense (red...

Coumestrol (Coumestan · Most Potent Plant Phytoestrogen · Bone Density)

Compound Coumestrol (3,9-Dihydroxy-6H-[1]benzofuro[3,2-c]chromen-6-one; Coumestane prototype) Chemical class Polyphenol — Coumestan (benzofuranone-fused chromene; biosynthetically related to isoflavones via 2-hydroxyisoflavanone oxidation) CAS 479-13-0 Primary source Medicago sativa (alfalfa sprouts), Trifolium pratense (red...