HerbIQ Reference Library  /  Compound Monographs

Active Compound Monographs

Dedicated technical dossiers detailing the molecular profile and evidence weight of individual plant bioactives

Where the Active Compound Index provides a high-level master matrix of the plant kingdom, these Compound Monographs serve as our definitive, independent deep dives. Each entry functions as a standalone scientific reference record—drilling past the surface to map out exact chemical identities, verified CAS numbers, and botanical source biologies with strict clinical objectivity.

Built specifically for product formulators, R&D teams, and researchers, this compendium translates raw plant chemistry into actionable data. Explore the individual monographs below to examine the detailed molecular structures and honest empirical data powering high-performance botanical nutrition.

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Lobeline (Piperidine Alkaloid · Nicotinic Partial Agonist · Lobelia · DAT Inhibition)

Alkaloid (Piperidine) from Indian Tobacco (Lobelia inflata). Studied as a nicotinic receptor partial agonist; historically used as a smoking cessation aid and expectorant. Limited.

Lobeline (Piperidine Alkaloid · Nicotinic Partial Agonist · Lobelia · DAT Inhibition)

Alkaloid (Piperidine) from Indian Tobacco (Lobelia inflata). Studied as a nicotinic receptor partial agonist; historically used as a smoking cessation aid and expectorant. Limited.

Piperine (Piperidine Amide · Bioavailability Enhancer · BioPerine · Thermogenic)

Alkaloid-related (Amide) from Black Pepper (Piper nigrum). A well-documented bioavailability enhancer; inhibits CYP3A4 and P-glycoprotein to significantly increase absorption of.

Piperine (Piperidine Amide · Bioavailability Enhancer · BioPerine · Thermogenic)

Alkaloid-related (Amide) from Black Pepper (Piper nigrum). A well-documented bioavailability enhancer; inhibits CYP3A4 and P-glycoprotein to significantly increase absorption of.

Nicotine (Pyridine Alkaloid · nAChR Agonist · NRT · Informational Reference)

Alkaloid (Pyridine) from Tobacco (Nicotiana tabacum). An acetylcholinergic stimulant; pharmacologically well-characterised. Associated with significant cardiovascular and.

Nicotine (Pyridine Alkaloid · nAChR Agonist · NRT · Informational Reference)

Alkaloid (Pyridine) from Tobacco (Nicotiana tabacum). An acetylcholinergic stimulant; pharmacologically well-characterised. Associated with significant cardiovascular and.

Sparteine (Quinolizidine Alkaloid · Antiarrhythmic · Uterotonic · CYP2D6 Probe)

Alkaloid (Quinolizidine) from Scotch Broom (Cytisus scoparius). A sodium and potassium channel blocker studied for antiarrhythmic and oxytocic properties.

Sparteine (Quinolizidine Alkaloid · Antiarrhythmic · Uterotonic · CYP2D6 Probe)

Alkaloid (Quinolizidine) from Scotch Broom (Cytisus scoparius). A sodium and potassium channel blocker studied for antiarrhythmic and oxytocic properties.

Symphytine (Comfrey Pyrrolizidine Alkaloid · Topical Context · PA Regulatory Reference)

Alkaloid (Pyrrolizidine) from Comfrey (Symphytum officinale). A hepatotoxic pyrrolizidine alkaloid found in comfrey root; the reason internal comfrey preparations are subject to.

Symphytine (Comfrey Pyrrolizidine Alkaloid · Topical Context · PA Regulatory Reference)

Alkaloid (Pyrrolizidine) from Comfrey (Symphytum officinale). A hepatotoxic pyrrolizidine alkaloid found in comfrey root; the reason internal comfrey preparations are subject to.

Monocrotaline (Pyrrolizidine Alkaloid · PAH Research Model · Pulmonary Toxin · Informational)

Alkaloid (Pyrrolizidine) from Rattlebox (Crotalaria spectabilis). Highly toxic to pulmonary vascular tissue; used experimentally in research models of pulmonary arterial hypertension.

Monocrotaline (Pyrrolizidine Alkaloid · PAH Research Model · Pulmonary Toxin · Informational)

Alkaloid (Pyrrolizidine) from Rattlebox (Crotalaria spectabilis). Highly toxic to pulmonary vascular tissue; used experimentally in research models of pulmonary arterial hypertension.

Senecionine (Pyrrolizidine Alkaloid · Hepatotoxic · HVOD · Regulatory Reference)

Alkaloid (Pyrrolizidine) from Ragwort (Senecio jacobaea). A hepatotoxic unsaturated pyrrolizidine alkaloid; associated with irreversible veno-occlusive liver disease. Strictly a.

Senecionine (Pyrrolizidine Alkaloid · Hepatotoxic · HVOD · Regulatory Reference)

Alkaloid (Pyrrolizidine) from Ragwort (Senecio jacobaea). A hepatotoxic unsaturated pyrrolizidine alkaloid; associated with irreversible veno-occlusive liver disease. Strictly a.

Veratramine (Veratrum Steroidal Alkaloid · Historical Antihypertensive · Informational)

Alkaloid (Steroidal) from False Hellebore (Veratrum viride). Highly toxic steroidal alkaloid associated with severe cardiovascular depression and CNS toxicity. Documented for.

Veratramine (Veratrum Steroidal Alkaloid · Historical Antihypertensive · Informational)

Alkaloid (Steroidal) from False Hellebore (Veratrum viride). Highly toxic steroidal alkaloid associated with severe cardiovascular depression and CNS toxicity. Documented for.

Jervine (Veratrum Steroidal Alkaloid · Primary Teratogen · Hedgehog Pathway · Informational)

Alkaloid (Steroidal) from Corn Lily (Veratrum californicum). A highly teratogenic steroidal alkaloid that disrupts CNS development.

Jervine (Veratrum Steroidal Alkaloid · Primary Teratogen · Hedgehog Pathway · Informational)

Alkaloid (Steroidal) from Corn Lily (Veratrum californicum). A highly teratogenic steroidal alkaloid that disrupts CNS development.

Cyclopamine (Veratrum Steroidal Alkaloid · Hedgehog Pathway · SMO Inhibitor · Teratogen)

Alkaloid (Steroidal) from Corn Lily (Veratrum californicum). A teratogenic Hedgehog signalling pathway inhibitor; studied in oncology research as a basis for targeted cancer.

Cyclopamine (Veratrum Steroidal Alkaloid · Hedgehog Pathway · SMO Inhibitor · Teratogen)

Alkaloid (Steroidal) from Corn Lily (Veratrum californicum). A teratogenic Hedgehog signalling pathway inhibitor; studied in oncology research as a basis for targeted cancer.

Peiminine — Isopeimine (Steroidal Alkaloid · Fritillaria · Antitussive · AChE Inhibitory)

Alkaloid (Steroidal) from Fritillary Bulb (Fritillaria thunbergii). Studied for anti-inflammatory and antitussive properties; may support soothing of throat mucosal irritation.

Peiminine — Isopeimine (Steroidal Alkaloid · Fritillaria · Antitussive · AChE Inhibitory)

Alkaloid (Steroidal) from Fritillary Bulb (Fritillaria thunbergii). Studied for anti-inflammatory and antitussive properties; may support soothing of throat mucosal irritation.

Peimine — Verticine (Steroidal Alkaloid · Fritillaria · Antitussive · TCM Respiratory)

Alkaloid (Steroidal) from Fritillary Bulb (Fritillaria thunbergii). Studied for expectorant and mucolytic properties; supports the traditional use of Fritillary bulb in respiratory.

Peimine — Verticine (Steroidal Alkaloid · Fritillaria · Antitussive · TCM Respiratory)

Alkaloid (Steroidal) from Fritillary Bulb (Fritillaria thunbergii). Studied for expectorant and mucolytic properties; supports the traditional use of Fritillary bulb in respiratory.

Conessine (Steroidal Alkaloid · Amoebicidal · Kutaj · IBS Diarrhoea)

Alkaloid (Steroidal) from Kurchi (Holarrhena pubescens). Studied for specific amoebicidal activity against Entamoeba histolytica.

Conessine (Steroidal Alkaloid · Amoebicidal · Kutaj · IBS Diarrhoea)

Alkaloid (Steroidal) from Kurchi (Holarrhena pubescens). Studied for specific amoebicidal activity against Entamoeba histolytica.

Solasodine (Steroidal Alkaloid · Hepatoprotective · Makoi · BCC Preclinical)

Alkaloid (Steroidal) from Devil's Apple (Solanum linnaeanum). A steroidal alkaloid used industrially as a starting material for the synthesis of pharmaceutical steroid hormones and.

Solasodine (Steroidal Alkaloid · Hepatoprotective · Makoi · BCC Preclinical)

Alkaloid (Steroidal) from Devil's Apple (Solanum linnaeanum). A steroidal alkaloid used industrially as a starting material for the synthesis of pharmaceutical steroid hormones and.

Tomatyna (glikoalkaloid steroidowy · działanie przeciwgrzybicze · wiązanie cholesterolu · prekursor tomatydyny)

Alkaloid (Steroidal) from Tomato (Solanum lycopersicum). A steroidal glycoalkaloid studied for antifungal activity and potential antiproliferative effects.

Tomatyna (glikoalkaloid steroidowy · działanie przeciwgrzybicze · wiązanie cholesterolu · prekursor tomatydyny)

Alkaloid (Steroidal) from Tomato (Solanum lycopersicum). A steroidal glycoalkaloid studied for antifungal activity and potential antiproliferative effects.

Chaconine — α-Chaconine (Steroidal Glycoalkaloid · Potato Co-toxin · Food Safety)

Alkaloid (Steroidal) from Potato (Solanum tuberosum). A glycoalkaloid that works in combination with solanine as a natural pest deterrent.

Chaconine — α-Chaconine (Steroidal Glycoalkaloid · Potato Co-toxin · Food Safety)

Alkaloid (Steroidal) from Potato (Solanum tuberosum). A glycoalkaloid that works in combination with solanine as a natural pest deterrent.

Solanine (Steroidal Glycoalkaloid · Potato Food Safety · Informational Reference)

Alkaloid (Steroidal) from Potato (Solanum tuberosum). A natural pesticide alkaloid toxic to insects and, at elevated levels, to humans.

Solanine (Steroidal Glycoalkaloid · Potato Food Safety · Informational Reference)

Alkaloid (Steroidal) from Potato (Solanum tuberosum). A natural pesticide alkaloid toxic to insects and, at elevated levels, to humans.

Galegina (alkaloid guanidynowy · roślinny prototyp metforminy · historia obniżania glikemii)

Alkaloid (Guanidine) from Goat's Rue (Galega officinalis). The botanical compound that inspired the development of metformin.

Galegina (alkaloid guanidynowy · roślinny prototyp metforminy · historia obniżania glikemii)

Alkaloid (Guanidine) from Goat's Rue (Galega officinalis). The botanical compound that inspired the development of metformin.

Kolchicyna (alkaloid tropolonowy · lek stosowany w dnie moczanowej · materiał informacyjny)

Alkaloid (Protoalkaloid) from Autumn Crocus (Colchicum autumnale). A clinically approved tubulin-binding anti-inflammatory used medically for acute gout attacks and familial.

Kolchicyna (alkaloid tropolonowy · lek stosowany w dnie moczanowej · materiał informacyjny)

Alkaloid (Protoalkaloid) from Autumn Crocus (Colchicum autumnale). A clinically approved tubulin-binding anti-inflammatory used medically for acute gout attacks and familial.

Ligustrazine — Tetramethylpyrazine (Pyrazine Alkaloid · Vasodilatory · Cerebrovascular · TCM)

Alkaloid (Pyrazine) from Chuanxiong (Ligusticum chuanxiong). Studied for vasodilatory and antiplatelet effects that may support cerebral and cardiovascular blood flow.

Ligustrazine — Tetramethylpyrazine (Pyrazine Alkaloid · Vasodilatory · Cerebrovascular · TCM)

Alkaloid (Pyrazine) from Chuanxiong (Ligusticum chuanxiong). Studied for vasodilatory and antiplatelet effects that may support cerebral and cardiovascular blood flow.

Deoxyvasicinone (Quinazoline Alkaloid · Synergistic Bronchodilation · Vasaka Co-alkaloid)

Alkaloid (Quinazoline) from Malabar Nut (Adhatoda vasica). Studied for synergistic bronchodilatory and mucus-clearing properties alongside vasicinone in respiratory health.

Deoxyvasicinone (Quinazoline Alkaloid · Synergistic Bronchodilation · Vasaka Co-alkaloid)

Alkaloid (Quinazoline) from Malabar Nut (Adhatoda vasica). Studied for synergistic bronchodilatory and mucus-clearing properties alongside vasicinone in respiratory health.

Vasicinone (Quinazoline Alkaloid · Bronchodilatory · Mucolytic · Vasaka)

Alkaloid (Quinazoline) from Malabar Nut (Adhatoda vasica). Studied for bronchodilatory and mucolytic properties; supports the traditional and clinical use of Adhatoda for.

Vasicinone (Quinazoline Alkaloid · Bronchodilatory · Mucolytic · Vasaka)

Alkaloid (Quinazoline) from Malabar Nut (Adhatoda vasica). Studied for bronchodilatory and mucolytic properties; supports the traditional and clinical use of Adhatoda for.

Capsaicin (Vanilloid Pseudoalkaloid · TRPV1 Agonist · Topical Analgesic · Thermogenic)

Vanilloid (Capsaicinoid) from Chili Pepper (Capsicum frutescens). A TRPV1 receptor agonist with well-documented topical analgesic applications.

Capsaicin (Vanilloid Pseudoalkaloid · TRPV1 Agonist · Topical Analgesic · Thermogenic)

Vanilloid (Capsaicinoid) from Chili Pepper (Capsicum frutescens). A TRPV1 receptor agonist with well-documented topical analgesic applications.

Linamarin (Cyanogenic Glycoside · Cassava Food Safety · HCN · Informational Reference)

Cyanogenic Glycoside from Cassava (Manihot esculenta). The primary cyanogenic glycoside of cassava; potentially toxic if cassava is insufficiently processed. Traditional and.

Linamarin (Cyanogenic Glycoside · Cassava Food Safety · HCN · Informational Reference)

Cyanogenic Glycoside from Cassava (Manihot esculenta). The primary cyanogenic glycoside of cassava; potentially toxic if cassava is insufficiently processed. Traditional and.