HerbIQ Resource Hub  /  Reference Index

Active Compound Index

A molecular-level reference for every bioactive compound in the botanical kingdom

The Active Compound Index is the molecular backbone of the HerbIQ framework. Where the four pillars explain how plant chemistry is sourced, extracted, formulated, and absorbed, this index answers the prior question: what exactly is in a plant, and what does science currently know about what it does? Every entry is a fixed scientific reference — not a health claim, but a structured record linking a molecule to its source biology, chemical identity, and the honest weight of available evidence.

The index is divided into two tables. Primary Metabolites are the cellular infrastructure — carbohydrates, lipids, proteins, vitamins and minerals every living plant cell requires. Secondary Metabolites are the bioactive signals — alkaloids, polyphenols, terpenoids, and glucosinolates responsible for the majority of pharmacologically interesting activity in botanical ingredients.

570+
Secondary
Metabolites
400+
Primary
Metabolites
16
Compound
Classes
9
Data Fields
per Entry

How to Read Each Entry

CompoundIUPAC or primary common name
Also Known AsTrade names, synonyms, regional names
ClassChemical family and sub-class
Plant SourcePrimary botanical origin
Botanical NameBinomial Latin species name
Plant PartTissue where compound concentrates
CAS No.Chemical Abstracts registry ID for cross-verification

Claim-Strength Policy

Every biological action statement uses conservative, hedged language: "studied for", "may support", "associated with". No entry makes a disease treatment claim. The badge reflects the weight of available evidence — not regulatory approval.

HighMultiple human RCTs or established clinical consensus
ModerateLimited human trials or strong mechanistic / animal data
EmergingPrimarily early-stage lab or in vitro research

← Swipe table to see all columns →

// PRIMARY METABOLITES: CELLULAR INFRASTRUCTURE
Compound Also Known As Class (Sub-class) Plant Source Botanical Name Plant Part CAS No. Claim Strength Primary Biological Action
MONOSACCHARIDES
D-GlucoseDextrose; Blood Sugar; Corn SugarCarbohydrates (Sugar / Monosaccharide)Sugar CaneSaccharum officinarumStem50-99-7HighThe fundamental source of fast-acting fuel for the human brain and muscle tissues.
D-FructoseLevulose; Fruit SugarCarbohydrates (Sugar / Monosaccharide)AppleMalus domesticaFruit57-48-7ModerateA natural sweetener that provides energy with a lower immediate insulin spike than glucose alone.
D-GalactoseBrain Sugar; CerebroseCarbohydrates (Sugar / Monosaccharide)SoybeanGlycine maxSeed59-23-4ModerateSupports the health of human nerve cells and is a component of healthy cell-to-cell communication.
D-MannoseCarbohydrates (Sugar / Monosaccharide)Guar BeanCyamopsis tetragonolobaSeed3458-28-4HighWidely used to support urinary tract health by preventing harmful bacteria from adhering to the bladder wall.
D-XyloseWood Sugar; Birch SugarCarbohydrates (Sugar / Monosaccharide)Birch TreeBetula spp.Wood58-86-6ModerateA low-calorie sugar used in wellness products to support healthy gut fermentation.
L-ArabinosePectin Sugar; Gum SugarCarbohydrates (Sugar / Monosaccharide)Sugar BeetBeta vulgarisRoot5328-37-0ModerateHelps manage blood sugar by inhibiting the enzyme that breaks down sucrose in the small intestine.
D-RiboseCarbohydrates (Sugar / Monosaccharide)All PlantsN/AEvery Cell50-69-1ModerateSupports heart health and athletic recovery by helping the body replenish its cellular energy (ATP) reserves.
2-Deoxy-D-riboseDeoxyribose; DNA SugarCarbohydrates (Sugar / Monosaccharide)All PlantsN/ANucleus533-67-5HighThe essential sugar found in every human cell that forms the backbone of our entire genetic code (DNA).
GlyceraldehydeD-Glyceraldehyde; GlyceralCarbohydrates (Sugar / Monosaccharide)SpinachSpinacia oleraceaChloroplast56-82-6EmergingA metabolic intermediate that researchers study to understand how humans process and convert dietary sugars.
DihydroxyacetoneDHA; GlyceroneCarbohydrates (Sugar / Monosaccharide)SpinachSpinacia oleraceaChloroplast96-26-4ModerateStudied for its role in cellular metabolism and widely used in topical wellness products for skin-toning.
D-ErythroseCarbohydrates (Sugar / Monosaccharide)Various PlantsN/ALeaves583-50-6EmergingA precursor for essential aromatic amino acids that must be obtained through a plant-rich diet.
D-ThreoseCarbohydrates (Sugar / Monosaccharide)Various PlantsN/ALeaves95-43-2EmergingA rare four-carbon sugar that serves as a biochemical research tool for studying carbohydrate metabolism.
D-RibuloseD-Erythro-2-pentuloseCarbohydrates (Sugar / Monosaccharide)All PlantsN/AChloroplast488-84-6EmergingA foundational photosynthetic molecule in the plants we eat, enabling them to convert CO₂ into food.
D-XyluloseD-threo-2-PentuloseCarbohydrates (Sugar / Monosaccharide)Various PlantsN/ALeaves551-84-8EmergingSupports the efficient recycling of carbon through key pentose phosphate metabolic pathways.
D-SedoheptuloseSedoheptuloseCarbohydrates (Sugar / Monosaccharide)StonecropSedum spectabileLeavesEmergingMay help regulate human energy metabolism; being studied for potential anti-diabetic properties.
MannoheptuloseCarbohydrates (Sugar / Monosaccharide)AvocadoPersea americanaFruitEmergingMay help modulate insulin secretion; studied for potential weight management and caloric restriction benefits.
D-AlloseCarbohydrates (Sugar / Monosaccharide)Protea ShrubProtea rubropilosaLeaves2595-97-3EmergingA rare sugar with documented anti-inflammatory and early-stage anticancer properties in laboratory studies.
D-AltroseCarbohydrates (Sugar / Monosaccharide)Rare VarietiesN/AVariousEmergingA rare sugar used in medical research to develop new antimicrobial treatment strategies.
D-GuloseCarbohydrates (Sugar / Monosaccharide)Various PlantsN/AVariousEmergingA glucose isomer used as a research marker for studying sugar transport mechanisms in human cells.
L-IdoseCarbohydrates (Sugar / Monosaccharide)Various PlantsN/AVariousEmergingA trace sugar used to understand the complex fiber structures in dietary plants that promote gut health.
D-TaloseCarbohydrates (Sugar / Monosaccharide)Various PlantsN/AVariousEmergingSupports biochemical research into how human cells recognize and bind to different sugar configurations.
D-Psicose (Allulose)Allulose; D-Allulose; Rare SugarCarbohydrates (Sugar / Monosaccharide)WheatTriticum aestivumGrains551-68-8ModerateA low-calorie sweetener that does not raise blood sugar and may help reduce visceral fat accumulation.
L-SorboseCarbohydrates (Sugar / Monosaccharide)Mountain AshSorbus aucupariaBerries87-79-6EmergingA rare industrial-route precursor used in Vitamin C manufacturing; studied for its own low-glycemic properties.
D-TagatoseCarbohydrates (Sugar / Monosaccharide)Sterculia GumSterculia urensExudate87-81-0ModerateA prebiotic sugar that supports healthy weight and dental wellness without promoting tooth decay.
L-Fucose6-Deoxy-L-galactoseCarbohydrates (Sugar / Monosaccharide)RockcressArabidopsis thalianaCell Wall2438-80-4ModerateEssential for human gut epithelial health and supports a strong, balanced innate immune response.
L-Rhamnose6-Deoxy-L-mannose; IsodulcitCarbohydrates (Sugar / Monosaccharide)BuckthornRhamnus spp.Bark3615-41-6ModerateA component of complex dietary fibers that helps maintain a resilient and healthy gut lining.
D-ApioseCarbohydrates (Sugar / Monosaccharide)ParsleyPetroselinum crispumLeavesEmergingA rare branched-chain sugar found in plant cell walls; studied for potential anti-inflammatory benefits.
L-Aceric AcidCarbohydrates (Sugar / Monosaccharide)SycamoreAcer pseudoplatanusCell WallEmergingA unique sugar component of complex dietary fibers; helps support a diverse and healthy gut microbiome.
D-Galacturonic AcidPectin Acid; GalACarbohydrates (Sugar / Monosaccharide)LemonCitrus limonPeel685-73-4ModerateThe primary structural unit of pectin, which binds dietary cholesterol and helps lower blood levels.
D-Glucuronic AcidGlcACarbohydrates (Sugar / Monosaccharide)Gum ArabicAcacia senegalSap6556-12-3ModerateAids the body’s natural detoxification processes and supports connective tissue and joint health.
Kdo (Octulosonic Acid)3-Deoxy-D-manno-octulosonic acid; KDOCarbohydrates (Sugar / Monosaccharide)All PlantsN/ACell WallEmergingUsed in research to understand how beneficial gut bacteria interact with the human intestinal wall.
Dha (Heptulosaric Acid)3-Deoxy-D-lyxo-heptulosaric acidCarbohydrates (Sugar / Monosaccharide)MossesPhyscomitrella patensCell WallEmergingA trace sugar component that contributes to the structural diversity of dietary plant cell-wall fiber.
NUCLEOTIDE SUGARS & PHOSPHORYLATED FORMS
D-Glucose-6-PhosphateG6P; Glucose-6-phosphate; Robison EsterCarbohydrates (Sugar / Monosaccharide)All PlantsN/AEvery CellHighA vital metabolic intermediate through which cells convert dietary sugar into the energy used for all life functions.
Fructose-1,6-BisphosphateF1,6BP; Harden-Young EsterCarbohydrates (Sugar / Monosaccharide)All PlantsN/AEvery CellHighA high-energy glycolytic intermediate that keeps cellular metabolism running efficiently during physical exercise.
UDP-GlucoseUridine Diphosphoglucose; UDPGCarbohydrates (Sugar / Monosaccharide)All PlantsN/AEvery CellModerateThe activated sugar donor form used to build essential glycoproteins that support immune system function.
GDP-MannoseGuanosine Diphosphate MannoseCarbohydrates (Sugar / Monosaccharide)All PlantsN/AEvery CellModerateFundamental for building cell-surface proteins that help the immune system distinguish self from pathogen.
UDP-Galacturonic AcidUDP-GalACarbohydrates (Sugar / Monosaccharide)All PlantsN/AEvery CellEmergingStudied by researchers to understand how plant fiber structures are built, informing improved fiber supplements.
ADP-GlucoseAdenosine DiphosphoglucoseCarbohydrates (Sugar / Monosaccharide)All PlantsN/APlastidModerateThe key activated donor for all plant starch biosynthesis; determines whether a food acts as a fast or slow carb.
Quinovose6-DeoxyglucoseCarbohydrates (Sugar / Monosaccharide)All Higher PlantsN/AChloroplastEmergingA crucial component of plant chloroplast membrane lipids that help maintain healthy human cell membrane fluidity.
AMINO SUGARS
Glucosamine2-Amino-2-deoxy-D-glucose; GlcN; ChitosamineCarbohydrates (Sugar / Monosaccharide)Neem TreeAzadirachta indicaSap3416-24-8HighOne of the most extensively validated supplements for protecting joint cartilage and reducing arthritis-related pain.
Galactosamine2-Amino-2-deoxy-D-galactose; GalN; ChondrosamineCarbohydrates (Sugar / Monosaccharide)Various PlantsN/AVarious7535-00-4ModerateSupports the structural health of joints, tendons, and heart valves as a key amino sugar building unit.
Mannosamine2-Amino-2-deoxy-D-mannose; ManNCarbohydrates (Sugar / Monosaccharide)Various PlantsN/AVariousEmergingUsed in research to develop new treatments for rare metabolic and immune-related disorders.
Rhamnosamine2-Amino-2-deoxy-L-rhamnoseCarbohydrates (Sugar / Monosaccharide)Various PlantsN/AVariousEmergingA rare amino sugar studied for its role in healthy signaling of human intestinal epithelial cells.
Quinovosamine2-Amino-2-deoxy-D-quinovoseCarbohydrates (Sugar / Monosaccharide)Various PlantsN/AVariousEmergingServes as a biochemical marker in laboratory tests for detecting and monitoring healthy cellular development.
DEOXYGENATED SUGARS
Abequose3,6-Dideoxy-D-galactoseCarbohydrates (Sugar / Monosaccharide)Rare VarietiesN/AVariousEmergingStudied for its ability to help beneficial gut bacteria identify and colonize the human intestinal environment.
Tyvelose3,6-Dideoxy-D-arabino-hexoseCarbohydrates (Sugar / Monosaccharide)Various PlantsN/AVariousEmergingA specialized surface sugar used to understand how the immune system recognizes and combats parasites.
Ascarylose3,6-Dideoxy-L-arabino-hexoseCarbohydrates (Sugar / Monosaccharide)Various PlantsN/AVariousEmergingA trace sugar from rare plants used to study how human cells adapt to different environmental stresses.
Olivose2,6-Dideoxy-D-arabino-hexoseCarbohydrates (Sugar / Monosaccharide)Various PlantsN/AVariousEmergingFound in natural plant antibiotics that protect against harmful bacterial overgrowth in the human body.
Amicetose2,3,6-Trideoxy-D-mannoseCarbohydrates (Sugar / Monosaccharide)Various PlantsN/AVariousEmergingContributes to the diversity of plant-derived deoxy sugars that support cellular defense mechanisms.
DISACCHARIDES
SucroseTable Sugar; Cane Sugar; Beet SugarCarbohydrates (Sugar / Disaccharide)Sugar BeetBeta vulgarisRoot57-50-1HighA dual-energy source (glucose + fructose) that should be consumed in moderation to support metabolic health.
MaltoseMalt Sugar; MaltobioseCarbohydrates (Sugar / Disaccharide)BarleyHordeum vulgareGrains69-79-4HighProvides a readily digestible, steady energy supply that supports physical activity and endurance.
TrehaloseMycose; Tremalose; Mushroom SugarCarbohydrates (Sugar / Disaccharide)Resurrection PlantSelaginella lepidophyllaWhole Plant99-20-7ModerateProtects human cells from dehydration and oxidative stress; studied for neuroprotective and anti-aging benefits.
Cellobiose4-O-β-D-Glucopyranosyl-D-glucoseCarbohydrates (Sugar / Disaccharide)CottonGossypium hirsutumFiber528-50-7ModerateActs as insoluble dietary roughage that helps maintain regularity and supports healthy colon function.
GentiobioseCarbohydrates (Sugar / Disaccharide)GentianGentiana luteaRoot554-91-6ModerateFound in bitter digestive tonics that stimulate healthy bile flow, enzyme secretion, and appetite.
Turanose3-O-α-D-Glucopyranosyl-D-fructoseCarbohydrates (Sugar / Disaccharide)Various NectarsN/AFlowersEmergingA low-glycemic nectar disaccharide that provides a slower, more sustained energy release than table sugar.
Isomaltose6-O-α-D-Glucopyranosyl-D-glucoseCarbohydrates (Sugar / Disaccharide)CornZea maysGrainsModerateA branched-chain disaccharide produced during slow starch digestion; supports a more balanced blood sugar response.
IsomaltulosePalatinoseCarbohydrates (Sugar / Disaccharide)Sugar CaneSaccharum officinarumSap13718-94-0HighA tooth-friendly sugar that releases energy slowly over several hours, avoiding the typical blood sugar spike.
Sophorose2-O-β-D-Glucopyranosyl-D-glucoseCarbohydrates (Sugar / Disaccharide)Sophora TreeStyphnolobium japonicumFruit6035-43-4EmergingStudied for its potential to boost the effectiveness of specific immune-supporting bioactive plant compounds.
Laminaribiose3-O-β-D-Glucopyranosyl-D-glucoseCarbohydrates (Sugar / Disaccharide)BarleyHordeum vulgareGrainsModerateFormed during the enzymatic breakdown of heart-healthy cereal β-glucan fiber; supports gut microflora.
Kojibiose2-O-α-D-Glucopyranosyl-D-glucoseCarbohydrates (Sugar / Disaccharide)CloverTrifolium spp.NectarEmergingA rare prebiotic disaccharide found in certain honeys; supports healthy gut microbial balance.
Nigerose3-O-α-D-Glucopyranosyl-D-glucoseCarbohydrates (Sugar / Disaccharide)BuckwheatFagopyrum esculentumSeedEmergingContributes to the immune-modulating properties found in certain traditional fermented plant-based foods.
Melibiose6-O-α-D-Galactopyranosyl-D-glucoseCarbohydrates (Sugar / Disaccharide)SoybeansGlycine maxSeed585-99-9ModerateA prebiotic disaccharide that helps increase the population of beneficial bifidobacteria in the colon.
Rutinose6-O-α-L-Rhamnosyl-D-glucoseCarbohydrates (Sugar / Disaccharide)BuckwheatFagopyrum esculentumLeavesModerateThe sugar carrier of rutin and related antioxidants that protect blood vessels and support circulation.
Neohesperidose2-O-α-L-Rhamnosyl-D-glucoseCarbohydrates (Sugar / Disaccharide)Bitter OrangeCitrus aurantiumFruit PeelModerateContributes to the digestion-stimulating and appetite-regulating effects of bitter citrus peel extracts.
Vicianose6-O-α-L-Arabinosyl-D-glucoseCarbohydrates (Sugar / Disaccharide)VetchVicia spp.SeedsEmergingFound in legumes as the sugar carrier for plant glycoside compounds; contributes to mild antioxidant activity.
Primeverose6-O-β-D-Xylopyranosyl-D-glucoseCarbohydrates (Sugar / Disaccharide)PrimrosePrimula spp.RootsEmergingProvides the sugar carrier for aromatic plant aglycones widely used in herbal wellness and aromatherapy.
Robinobiose6-O-α-L-Rhamnosyl-D-galactoseCarbohydrates (Sugar / Disaccharide)Locust TreeRobinia pseudoacaciaFlowersEmergingA specialized carrier sugar that transports health-relevant plant flavonoid compounds into the body.
ScillabioseCarbohydrates (Sugar / Disaccharide)SquillDrimia maritimaBulbEmergingHistorically used in heart-related wellness preparations to support healthy circulatory function.
StrophanthobioseCarbohydrates (Sugar / Disaccharide)StrophanthusStrophanthus spp.SeedsEmergingA carrier disaccharide studied for its role in delivering heart-active cardiotonic glycoside compounds.
InulobioseCarbohydrates (Fiber / Disaccharide)ChicoryCichorium intybusRootModerateThe repeating β(2→1) fructose-fructose unit of prebiotic inulin; essential marker for dietary fiber quality.
LevanobioseCarbohydrates (Fiber / Disaccharide)Timothy GrassPhleum pratenseLeavesModerateA β(2→6)-linked fructose disaccharide; the structural unit of levan fiber with prebiotic and heart-healthy properties.
OLIGOSACCHARIDES
RaffinoseMelitose; GossyposeCarbohydrates (Sugar / Oligosaccharide)PeaPisum sativumSeed512-69-6ModerateA common prebiotic that selectively feeds beneficial gut microbes; may cause gas in sensitive individuals.
StachyoseLupeoseCarbohydrates (Sugar / Oligosaccharide)SoybeansGlycine maxSeed470-55-3ModerateFuels beneficial bacteria in the colon, supporting digestive immunity and a balanced gut microbiome.
VerbascoseCarbohydrates (Sugar / Oligosaccharide)MulleinVerbascum spp.SeedModerateA prebiotic pentasaccharide found in legumes and grains that supports a diverse and healthy gut environment.
AjugoseCarbohydrates (Sugar / Oligosaccharide)BugleweedAjuga reptansLeavesEmergingA five-unit fructooligosaccharide being studied for its long-term prebiotic benefits to lower colon health.
UmbelliferoseCarbohydrates (Sugar / Oligosaccharide)CarrotDaucus carotaRootEmergingUnique to the Apiaceae (carrot) family; contributes to the prebiotic activity of root vegetable fibers.
CiceritolCarbohydrates (Sugar / Oligosaccharide)ChickpeaCicer arietinumSeedModerateImproves digestive health by selectively promoting the growth of beneficial Bifidobacteria in the intestine.
1-KestoseGF2; 1F-FructosylsucroseCarbohydrates (Sugar / Oligosaccharide)OnionAllium cepaBulbModerateA short-chain FOS highly effective at reducing gut inflammation and reinforcing the intestinal barrier function.
NystoseGF3; FructosylkestoseCarbohydrates (Sugar / Oligosaccharide)AsparagusAsparagus officinalisSpearModerateSupports metabolic wellness and has been shown to improve intestinal absorption of calcium from food.
FructofuranosylnystoseGF4; Fructooligosaccharide DP4Carbohydrates (Sugar / Oligosaccharide)GarlicAllium sativumBulbModerateEnhances immune function by selectively supporting the growth of beneficial bifidobacteria and lactobacilli.
MelezitoseCarbohydrates (Sugar / Oligosaccharide)LarchLarix occidentalisSapModerateA three-unit sugar found in honeydew honey; provides a steady energy release with a low insulin response.
PlanteoseCarbohydrates (Sugar / Oligosaccharide)PlantainPlantago spp.SeedModerateFound in Plantago seeds; contributes to the mucilaginous, digestion-soothing properties of the whole seed.
ErloseCarbohydrates (Sugar / Oligosaccharide)Various PlantsN/ANectarEmergingA minor trisaccharide component of raw honey and nectar; contributes to its overall nutritional energy profile.
MaltotrioseCarbohydrates (Sugar / Oligosaccharide)RiceOryza sativaGrains1109-28-0ModerateA three-unit glucose chain released during starch digestion; provides a source of sustained physical energy.
PanoseCarbohydrates (Sugar / Oligosaccharide)CornZea maysGrainsModerateA branched glucose trisaccharide from slow-digesting starches; helps maintain balanced blood sugar after meals.
MaltotetraoseCarbohydrates (Sugar / Oligosaccharide)CornZea maysGrainsModerateUsed in clinical nutrition to provide sustained, controlled energy delivery for patients with metabolic needs.
GalactotetraoseCarbohydrates (Sugar / Oligosaccharide)SoybeanGlycine maxSeedModerateA complex prebiotic oligosaccharide that helps protect the gut mucosa from inflammatory insult.
VerbascotetraoseCarbohydrates (Sugar / Oligosaccharide)MulleinVerbascum spp.SeedEmergingA four-unit oligosaccharide that helps moderate the enzymatic digestion rate of dietary starches.
LychnoseCarbohydrates (Sugar / Oligosaccharide)CampionSilene spp.RootsEmergingA rare tetrasaccharide with prebiotic potential; studied for its benefits to lower digestive tract health.
IsolychnoseCarbohydrates (Sugar / Oligosaccharide)LychnisLychnis spp.RootsEmergingActs as a specialized plant fiber to help improve the frequency and comfort of healthy digestion.
IsomaltotrioseCarbohydrates (Sugar / Oligosaccharide)CornZea maysGrainsModerateSlows glucose absorption from branched starches, helping to keep post-meal insulin levels stable.
NeokestoseCarbohydrates (Sugar / Oligosaccharide)OnionAllium cepaBulbModerateA high-potency prebiotic shown to help lower blood cholesterol and triglyceride levels.
MaltopentaoseCarbohydrates (Sugar / Oligosaccharide)CornZea maysGrainsModerateA five-unit glucose chain used in clinical nutrition for controlled energy release in metabolic conditions.
MaltohexaoseCarbohydrates (Sugar / Oligosaccharide)CornZea maysGrainsModerateSupports long-term glycogen energy stores in the body during periods of sustained physical activity.
MaltoheptaoseCarbohydrates (Sugar / Oligosaccharide)CornZea maysGrainsModerateA seven-unit glucose chain allowing controlled release of glucose into the bloodstream over several hours.
GentianoseCarbohydrates (Sugar / Oligosaccharide)GentianGentiana luteaRootModerateProvides the signature bitter prebiotic activity that supports healthy digestive flow and enzyme secretion.
MannotrioseCarbohydrates (Sugar / Oligosaccharide)Ivory Nut PalmPhytelephas spp.SeedEmergingA slow-digesting mannose trisaccharide that supports a steady and healthy metabolic energy rate.
XylotrioseCarbohydrates (Sugar / Oligosaccharide)WheatTriticum aestivumStemEmergingA xylose-derived oligosaccharide contributing to insoluble roughage that supports a healthy, clean colon.
ArabinotrioseCarbohydrates (Sugar / Oligosaccharide)All PlantsN/ACell WallEmergingA cell-wall fiber breakdown product that helps soften the stool and ease digestive transit.
CellotrioseCarbohydrates (Sugar / Oligosaccharide)CottonGossypium hirsutumFiberEmergingA cellulose-derived roughage oligosaccharide that helps manage inflammation in the lower gut.
SUGAR ALCOHOLS (POLYOLS)
MannitolMannite; Manna Sugar; E421Carbohydrates (Sugar / Sugar Alcohol)Olive TreeOlea europaeaLeaves69-65-8HighA powerful osmotic agent and antioxidant that can cross the blood-brain barrier to protect the nervous system.
SorbitolGlucitol; D-Sorbitol; E420Carbohydrates (Sugar / Sugar Alcohol)AppleMalus domesticaFruit50-70-4HighA natural sugar substitute and osmotic laxative used in diabetic-friendly products to support regularity.
XylitolBirch Sugar; E967Carbohydrates (Sugar / Sugar Alcohol)Birch TreeBetula spp.Bark87-99-0HighClinically proven to prevent tooth decay and inhibit the bacteria responsible for ear infections.
ErythritolMeso-erythritol; E968Carbohydrates (Sugar / Sugar Alcohol)StrawberryFragaria spp.Fruit149-32-6HighA nearly zero-calorie sweetener that protects against dental cavities and is exceptionally well-tolerated by the gut.
GalactitolDulcitolCarbohydrates (Sugar / Sugar Alcohol)Spindle TreeEuonymus spp.Leaves608-66-2EmergingStudied for its potential to help regulate osmotic water balance in human cells under metabolic stress.
Myo-inositolInositol; Vitamin B8 (unofficial); CyclohexanehexolCarbohydrates (Sugar / Sugar Alcohol)All PlantsN/AEvery Cell87-89-8HighVital for women’s reproductive health and hormonal balance; well-validated for improving mood and insulin sensitivity.
VolemitolD-β-SedoheptitolCarbohydrates (Sugar / Sugar Alcohol)CowslipPrimula verisRootEmergingA specialized seven-carbon polyol that provides low-calorie energy support for a healthy metabolism.
PersitolCarbohydrates (Sugar / Sugar Alcohol)AvocadoPersea americanaFruitEmergingA rare polyol contributing to the heart-healthy nutritional profile of avocados; may support satiety signals.
RibitolAdonitolCarbohydrates (Sugar / Sugar Alcohol)Pheasant’s EyeAdonis spp.Whole Plant488-81-3ModerateA critical structural molecule the body uses in the synthesis of Vitamin B2 (Riboflavin) for cellular energy.
ArabitolArabinitolCarbohydrates (Sugar / Sugar Alcohol)Lichens / AlgaeN/AWhole BodyEmergingAssists in the healthy fermentation of dietary plant fibers by bacteria in the lower digestive tract.
ThreitolL-ThreitolCarbohydrates (Sugar / Sugar Alcohol)Various PlantsN/ALeavesEmergingFunctions as a natural antioxidant that helps neutralize harmful free radicals within the body.
D-Bornesitol1-O-Methyl-D-myo-inositolCarbohydrates (Sugar / Sugar Alcohol)LitchiLitchi chinensisLeavesEmergingA methylated inositol that improves cellular glucose uptake, helping to lower blood sugar naturally.
D-Ononitol4-O-Methyl-D-myo-inositolCarbohydrates (Sugar / Sugar Alcohol)Pigeon PeaCajanus cajanLeavesEmergingSupports cellular health during physical stress and helps maintain osmotic water balance in the body.
Sequoyitol5-O-Methyl-myo-inositolCarbohydrates (Sugar / Sugar Alcohol)RedwoodSequoia sempervirensHeartwoodEmergingProvides metabolic support and has been investigated for potential anti-diabetic and antioxidant activity.
D-Pinitol3-O-Methyl-D-chiro-inositol; PinitolCarbohydrates (Sugar / Sugar Alcohol)Carob TreeCeratonia siliquaLeaves525-01-9ModerateA powerful insulin-sensitizing compound that helps the human body manage blood glucose more efficiently.
Pinpollitol3-O-Methyl-D-pinitolCarbohydrates (Sugar / Sugar Alcohol)Pine TreePinus spp.SapEmergingStudied for systemic water balance management and potential support for metabolic kidney function.
Quebrachitol2-O-Methyl-L-chiro-inositolCarbohydrates (Sugar / Sugar Alcohol)Rubber TreeHevea brasiliensisLatex480-40-0EmergingStudied as a health-promoting agent for managing metabolic conditions, with potential gut-supportive properties.
D-GlucosaminitolCarbohydrates (Sugar / Sugar Alcohol)Various PlantsN/AVariousEmergingA reduced amino sugar studied for its ability to send healing signals through connective tissues.
D-RhamnitolL-RhamnitolCarbohydrates (Sugar / Sugar Alcohol)Various PlantsN/AVariousEmergingUsed in wellness research to study healthy cellular water distribution and protection from dehydration.
L-FucitolCarbohydrates (Sugar / Sugar Alcohol)Various PlantsN/AVariousEmergingAssists the body in maintaining its natural antioxidant shield under conditions of physical and oxidative stress.
D-GalactosaminitolCarbohydrates (Sugar / Sugar Alcohol)Various PlantsN/AVariousEmergingA vital biochemical intermediate helping scientists understand how the body synthesizes brain-healthy lipids.
STARCHES (POLYSACCHARIDES)
AmyloseCarbohydrates (Starch / Polysaccharide)RiceOryza sativaGrains9005-82-7ModerateA linear ‘slow carb’ that digests gradually, providing stable blood energy and promoting prolonged satiety.
AmylopectinCarbohydrates (Starch / Polysaccharide)PotatoSolanum tuberosumTuber9037-22-3ModerateProvides rapidly available, highly branched glucose chains for quick muscle energy recovery after exertion.
FIBER POLYSACCHARIDES — PLANT
InulinChicory Fiber; Fructan; Alant StarchCarbohydrates (Fiber / Polysaccharide)ChicoryCichorium intybusRoot9005-80-5HighImproves bone mineral density by enhancing calcium absorption; lowers blood triglycerides and feeds beneficial gut flora.
LevanBacterial Fructan (class)Carbohydrates (Fiber / Polysaccharide)GrassesPoaceaeStems9013-95-0ModerateA β(2→6)-linked fructan fiber that helps reduce blood cholesterol and supports immune system modulation.
CelluloseMicrocrystalline Cellulose (MCC); E460Carbohydrates (Fiber / Polysaccharide)CottonGossypium hirsutumSeed Fiber9004-34-6HighProvides essential bulk to the diet, promoting regularity and reducing the risk of colorectal complications.
XyloglucanTamarind Seed Polysaccharide (TSP)Carbohydrates (Fiber / Polysaccharide)TamarindTamarindus indicaSeed37294-28-3ModerateUsed in research to protect stomach and intestinal mucosal linings and to support skin barrier function.
ArabinoxylanAXOS (oligomeric form)Carbohydrates (Fiber / Polysaccharide)WheatTriticum aestivumBran68911-25-1ModerateSignificantly lowers postprandial blood sugar response and promotes the selective growth of healthy gut bacteria.
GlucomannanKonjac Fiber; KGM; Konjac GlucomannanCarbohydrates (Fiber / Polysaccharide)KonjacAmorphophallus konjacTuber37220-17-0HighA clinically validated super-fiber that promotes significant weight management by inducing prolonged satiety.
Galactomannan(Source-specific, e.g. Guar Galactomannan)Carbohydrates (Fiber / Polysaccharide)Guar BeanCyamopsis tetragonolobaSeed11078-30-1HighClinically shown to lower LDL cholesterol and slow the intestinal absorption of dietary sugars.
GlucuronoxylanCarbohydrates (Fiber / Polysaccharide)Birch TreeBetula spp.WoodModerateA hardwood hemicellulose fiber that supports the selective growth of healthy bacteria in the large intestine.
GalactoglucomannanCarbohydrates (Fiber / Polysaccharide)Pine TreePinus spp.WoodModerateStudied for its ability to modulate immune function and support overall gut microbial balance.
Mixed-linkage Beta-glucanOat Beta-Glucan; Cereal Beta-Glucan; (1→3),(1→4)-β-D-glucanCarbohydrates (Fiber / Polysaccharide)OatsAvena sativaGrains9041-22-9HighCarries an FDA Qualified Health Claim for reducing LDL cholesterol and lowering the risk of heart disease.
HomogalacturonanPectin backbone; HGACarbohydrates (Fiber / Polysaccharide)AppleMalus domesticaFruitModerateThe primary pectin domain that binds dietary cholesterol and environmental heavy metals for elimination.
Rhamnogalacturonan IRG-ICarbohydrates (Fiber / Polysaccharide)CarrotDaucus carotaRootModerateBoosts the body’s natural defense against seasonal viruses and supports a resilient intestinal barrier.
Rhamnogalacturonan IIRG-IICarbohydrates (Fiber / Polysaccharide)Wine GrapesVitis viniferaFruitModerateA highly complex pectin domain that helps maintain the structural integrity of the human intestinal wall.
XylogalacturonanXGACarbohydrates (Fiber / Polysaccharide)PeaPisum sativumPodModerateA pectin sub-domain that supports long-term digestive regularity and prevents postprandial insulin spikes.
ApiogalacturonanCarbohydrates (Fiber / Polysaccharide)DuckweedLemna minorWhole PlantEmergingA specialized pectin-domain fiber that promotes a diverse and healthy population of gut bacteria.
ArabinanCarbohydrates (Fiber / Polysaccharide)Sugar BeetBeta vulgarisRootModerateA branched arabinose-rich fiber that acts as a gentle prebiotic, improving stool consistency and digestive ease.
GalactanCarbohydrates (Fiber / Polysaccharide)PotatoSolanum tuberosumTuberModerateSupports the renewal and structural integrity of the protective mucus layer in the stomach and intestines.
ArabinogalactanAG; Larch ArabinogalactanCarbohydrates (Fiber / Polysaccharide)Larch TreeLarix occidentalisWoodModerateSignificantly increases beneficial gut bacteria counts and supports immune function via multiple human trials.
Gum ArabicAcacia Gum; E414Carbohydrates (Fiber / Polysaccharide)Acacia TreeAcacia senegalSap9000-01-5ModerateReduces systemic inflammation and promotes satiety, aiding in healthy weight management and gut balance.
Gum TragacanthE413Carbohydrates (Fiber / Polysaccharide)AstragalusAstragalus brachycalyxSap9000-65-1ModerateA traditional soothing remedy for digestive irritation; used as a prebiotic and to support skin health.
Gum KarayaSterculia Gum; E416Carbohydrates (Fiber / Polysaccharide)Sterculia TreeSterculia urensSap9000-36-6ModerateA natural bulk-forming laxative that is gentle and consistently effective for managing digestive health.
Gum GhattiE419Carbohydrates (Fiber / Polysaccharide)AxlewoodAnogeissus latifoliaSap9000-28-6ModerateSupports the controlled release of nutrients in the gut, ensuring a steady and comfortable energy absorption.
Albizia GumCarbohydrates (Fiber / Polysaccharide)AlbiziaAlbizia zygiaSapEmergingUsed in wellness products to support healthy gut microflora populations and promote smooth, comfortable digestion.
Khaya GumAfrican Mahogany GumCarbohydrates (Fiber / Polysaccharide)MahoganyKhaya grandifoliolaSapEmergingA prebiotic exudate gum that helps maintain a healthy balance of bacteria in the human colon.
Neem GumCarbohydrates (Fiber / Polysaccharide)Neem TreeAzadirachta indicaSapModeratePossesses natural gastroprotective properties that help shield the stomach mucosa from ulcers and irritation.
Cashew GumCarbohydrates (Fiber / Polysaccharide)Cashew TreeAnacardium occidentaleSapModerateProvides a protective coating for the digestive tract and has documented immunostimulatory properties.
Almond GumCarbohydrates (Fiber / Polysaccharide)Almond TreePrunus dulcisSapModerateTraditionally used to soothe dry coughs and sore throats when used in herbal wellness infusions.
Okra MucilageCarbohydrates (Fiber / Polysaccharide)OkraAbelmoschus esculentusFruit PodModerateBinds to dietary toxins and cholesterol in the gut, helping to reduce their absorption into the bloodstream.
Psyllium MucilageIspaghula; Psyllium Husk Fiber; Plantago FiberCarbohydrates (Fiber / Polysaccharide)PlantagoPlantago ovataSeed Husk9067-32-7HighOne of the most clinically validated fibers for reducing LDL cholesterol and supporting long-term digestive regularity.
Flaxseed MucilageLinseed Mucilage; Flaxseed FiberCarbohydrates (Fiber / Polysaccharide)FlaxLinum usitatissimumSeed CoatModerateClinical evidence supports its role in reducing blood pressure and inflammation while supporting hormonal balance.
Chia MucilageChia Seed Fiber; Chia GelCarbohydrates (Fiber / Polysaccharide)ChiaSalvia hispanicaSeedModeratePromotes hydration and stable blood sugar by forming a gel that slows carbohydrate digestion and absorption.
Tamarind Seed PolysaccharideTSP; Tamarind XyloglucanCarbohydrates (Fiber / Polysaccharide)TamarindTamarindus indicaSeedModerateSupports immune function; used in clinical ophthalmic research to protect and hydrate eye surface tissues.
Locust Bean GumCarob Gum; LBG; E410Carbohydrates (Fiber / Polysaccharide)Carob TreeCeratonia siliquaSeed9000-40-6HighClinically used to manage infant reflux and shown to support healthy postprandial blood sugar in adults.
Guar GumGuar; Jaguar Gum; E412Carbohydrates (Fiber / Polysaccharide)GuarCyamopsis tetragonolobaSeed9000-30-0HighClinically validated for treating irritable bowel syndrome (IBS) and improving overall gut motility.
Tara GumE417Carbohydrates (Fiber / Polysaccharide)Tara TreeCaesalpinia spinosaSeedModerateA gentle, well-tolerated galactomannan fiber that supports regularity and promotes a feeling of fullness.
Slippery Elm MucilageCarbohydrates (Fiber / Polysaccharide)Slippery ElmUlmus rubraInner BarkModerateCreates a soothing, protective coating in the human throat and stomach, effectively easing acid reflux discomfort.
Aloe Vera Gel (Acemannan)Acemannan; Aloe PolysaccharideCarbohydrates (Fiber / Polysaccharide)AloeAloe veraLeavesModerateWell-supported for internal gut healing and repair and external skin hydration and wound recovery.
Marshmallow MucilageAlthaea MucilageCarbohydrates (Fiber / Polysaccharide)Marsh MallowAlthaea officinalisRootModerateHighly effective for soothing irritated mucosal linings in both the respiratory and digestive systems.
Cactus MucilageNopal Fiber; Prickly Pear PolysaccharideCarbohydrates (Fiber / Polysaccharide)Prickly PearOpuntia ficus-indicaStem PadModerateHelps lower blood sugar and blood cholesterol while providing deep hydration to body tissues.
Fenugreek MucilageFenugreek Fiber; Trigonella GalactomannanCarbohydrates (Fiber / Polysaccharide)FenugreekTrigonella foenum-graecumSeedModerateCommonly used to improve insulin sensitivity; well-supported for healthy breast milk production in nursing mothers.
Quince MucilageQuince Seed PolysaccharideCarbohydrates (Fiber / Polysaccharide)QuinceCydonia oblongaSeedModeratePossesses natural antibacterial properties that help maintain the health of the mouth and digestive tract.
Mullein MucilageCarbohydrates (Fiber / Polysaccharide)MulleinVerbascum spp.LeavesModerateSupports lung health by helping to loosen and clear mucus while soothing the respiratory mucous membrane.
Licorice MucilageLicorice Root PolysaccharideCarbohydrates (Fiber / Polysaccharide)LicoriceGlycyrrhiza glabraRootModerateWell-documented for helping heal stomach ulcers and providing a soothing effect on the digestive system.
Malabar Spinach MucilageBasella MucilageCarbohydrates (Fiber / Polysaccharide)Malabar SpinachBasella albaLeavesModerateA cooling wellness food that supports gentle detoxification and helps naturally reduce body heat.
Jute MucilageCorchorus MucilageCarbohydrates (Fiber / Polysaccharide)JuteCorchorus spp.LeavesModerateRich in antioxidant polysaccharides and dietary fibers that support healthy skin and overall digestion.
Nagaimo MucilageChinese Yam Mucilage; YamaimoCarbohydrates (Fiber / Polysaccharide)Chinese YamDioscorea polystachyaTuberModerateA traditional wellness food widely used to boost kidney health and support physical stamina and vitality.
Sundew MucilageCarbohydrates (Fiber / Polysaccharide)SundewDrosera spp.LeavesEmergingStudied for its potential to act as a natural anti-inflammatory for muscle and joint discomfort.
Butterwort MucilageCarbohydrates (Fiber / Polysaccharide)ButterwortPinguicula spp.LeavesEmergingA rare biological adhesive used in research to understand how polysaccharides can address microbial infections.
Callose(1→3)-β-D-Glucan (plant)Carbohydrates (Fiber / Polysaccharide)All Higher PlantsN/APhloemEmergingA structural β-glucan that researchers use to study how the human body initiates and manages wound healing.
XylinanXylan (hardwood form)Carbohydrates (Fiber / Polysaccharide)Hardwood TreesN/AHeartwoodModerateProvides extremely tough insoluble dietary roughage that helps sweep the colon clean of metabolic waste.
FIBER POLYSACCHARIDES — MARINE & ALGAL
Paramylon(1→3)-β-D-Glucan (Euglena)Carbohydrates (Fiber / Polysaccharide)EuglenaEuglena gracilisWhole CellEmergingA unique microalgal beta-glucan being studied for its ability to significantly enhance the human immune response.
Laminarin(1→3),(1→6)-β-D-Glucan (marine)Carbohydrates (Fiber / Polysaccharide)Brown AlgaeLaminaria spp.Whole BodyModerateAn algal fiber shown to help lower blood pressure and support overall cardiovascular system health.
Alginic AcidAlginate; Algin; E400Carbohydrates (Fiber / Polysaccharide)KelpMacrocystis pyriferaCell Wall9005-32-7ModerateUsed clinically to treat acid reflux by forming a viscous raft that physically prevents stomach acid from rising.
CarrageenanIrish Moss Extract; E407Carbohydrates (Fiber / Polysaccharide)Irish MossChondrus crispusCell Wall9000-07-1ModerateA sulfated seaweed polysaccharide gel that can support digestive health when consumed in food-grade form.
AgarAgar-agar; Kanten; E406Carbohydrates (Fiber / Polysaccharide)Red SeaweedGelidium spp.Cell Wall9002-18-0ModerateA calorie-free gelling fiber that promotes satiety and aids weight management by increasing food volume.
FucoidanSulfated Fucose Polymer; Brown Algae ExtractCarbohydrates (Fiber / Polysaccharide)BladderwrackFucus vesiculosusSurface9072-19-9ModerateA well-studied marine polysaccharide with documented antiviral, anticoagulant, and early-stage anticancer properties.
UlvanCarbohydrates (Fiber / Polysaccharide)Sea LettuceUlva lactucaCell WallEmergingSupports human detoxification pathways and helps maintain a healthy immune balance in the gut.
PorphyranCarbohydrates (Fiber / Polysaccharide)NoriPorphyra spp.Cell WallEmergingStudied for its ability to improve fat metabolism and protect the liver from oxidative damage.
LichenanMixed-linkage β-glucan (lichen)Carbohydrates (Fiber / Polysaccharide)Iceland MossCetraria islandicaThallusModerateA traditional respiratory soother; provides slow-release energy and supports the body’s mucosal defenses.
Pustulan(1→6)-β-D-Glucan (lichen)Carbohydrates (Fiber / Polysaccharide)Rock TripeLasallia pustulataThallusEmergingUsed as a molecular research tool to investigate new ways to boost human intestinal immunity.
FIBER POLYSACCHARIDES — FUNGAL
ChitinPoly-GlcNAc; Fungal FiberCarbohydrates (Fiber / Polysaccharide)MushroomsAgaricus bisporusCell Wall1398-61-4ModerateProvides structural roughage that aids in healthy weight management and promotes colon health.
LentinanShiitake Beta-Glucan; LNTCarbohydrates (Fiber / Polysaccharide)ShiitakeLentinula edodesFruit Body37339-90-5ModerateA clinically used immunostimulant (approved in Japan) that helps the body defend against tumors and viral infections.
SchizophyllanSonifilan; SPG; SIZOFIRANCarbohydrates (Fiber / Polysaccharide)Splitgill MushroomSchizophyllum communeMyceliumModerateInvestigated for its ability to stimulate production of infection-fighting white blood cells via NK cell activation.
ScleroglucanCarbohydrates (Fiber / Polysaccharide)Soil FungiSclerotium spp.MyceliumEmergingUsed in wellness products to provide sustained skin hydration and topical barrier support.
PullulanE1204Carbohydrates (Fiber / Polysaccharide)FungiAureobasidium pullulansSurface9057-02-7ModerateA food-grade biopolymer used in dissolvable wellness films and capsules; safe and easily digested.
FATTY ACIDS — SATURATED
Lauric AcidDodecanoic acid; C12:0Lipids (Fatty Acid / Saturated)Coconut PalmCocos nuciferaEndosperm143-07-7ModerateA medium-chain saturated fatty acid that is rapidly metabolised for energy; may support healthy immune function.
Myristic AcidTetradecanoic acid; C14:0Lipids (Fatty Acid / Saturated)NutmegMyristica fragransSeed544-63-8ModeratePlays a structural role in anchoring proteins to cell membranes and may contribute to healthy cellular signalling.
Palmitic AcidHexadecanoic acid; C16:0Lipids (Fatty Acid / Saturated)Palm TreeElaeis guineensisFruit Mesocarp57-10-3HighA foundational saturated fatty acid that serves as a key energy substrate and essential structural component of human cell membranes.
Stearic AcidOctadecanoic acid; C18:0Lipids (Fatty Acid / Saturated)Cocoa TreeTheobroma cacaoSeed (Bean)57-11-4HighA stable saturated fatty acid providing sustained energy; appears to have a more neutral effect on blood cholesterol than shorter-chain saturated fats.
Arachidic AcidEicosanoic acid; C20:0Lipids (Fatty Acid / Saturated)PeanutArachis hypogaeaSeed506-30-9EmergingA minor long-chain saturated fatty acid that may contribute to long-term energy storage and structural cell membrane integrity.
Behenic AcidDocosanoic acid; C22:0Lipids (Fatty Acid / Saturated)MoringaMoringa oleiferaSeed112-85-6ModerateWidely used in topical formulations for emollient properties; may support skin smoothness and moisture retention.
Lignoceric AcidTetracosanoic acid; C24:0Lipids (Fatty Acid / Saturated)PeanutArachis hypogaeaSeed557-59-5ModerateA very long-chain fatty acid that forms part of the brain's myelin sheath structure, supporting nerve insulation and integrity.
FATTY ACIDS — MONOUNSATURATED
Palmitoleic AcidC16:1 n-7; Omega-7Lipids (Fatty Acid / Monounsaturated)MacadamiaMacadamia integrifoliaNut373-49-9ModerateMay support metabolic health and help maintain mucosal lining hydration; studied for potential lipid-management benefits.
Petroselinic AcidC18:1 (6Z); Delta-6-octadecenoic acidLipids (Fatty Acid / Monounsaturated)ParsleyPetroselinum crispumSeed593-39-5EmergingMay contribute to skin health and localised inflammation modulation; studied for cosmetic and topical wellness applications.
Oleic AcidOctadecenoic acid; C18:1 n-9; Omega-9Lipids (Fatty Acid / Monounsaturated)Olive TreeOlea europaeaFruit112-80-1HighA well-documented heart-supportive fatty acid; consistently associated with healthy arterial function and favourable lipid profiles as part of a balanced diet.
Gadoleic AcidC20:1 n-9; Eicosenoic acidLipids (Fatty Acid / Monounsaturated)RapeseedBrassica napusSeedEmergingContributes to fatty acid diversity in cell membranes; studied for its minor role in lipid metabolism and chain elongation.
Gondoic AcidC20:1 n-11; Eicosenoic acid (n-11)Lipids (Fatty Acid / Monounsaturated)JojobaSimmondsia chinensisSeedModerateClosely resembles the body's natural sebum; may support skin and hair hydration in topical wellness formulations.
Erucic AcidC22:1 n-9; Long-chain Omega-9Lipids (Fatty Acid / Monounsaturated)MustardBrassica nigraSeed112-86-7ModerateStudied in specific therapeutic contexts for neurological support; dietary intake is subject to regulatory guidance in many markets due to cardiac safety considerations.
Nervonic AcidSelacholeic acid; C24:1 n-9Lipids (Fatty Acid / Monounsaturated)Honesty PlantLunaria annuaSeed Oil506-37-6ModerateA very long-chain fatty acid considered important for maintaining the structural health of the brain's white matter and myelin insulation.
FATTY ACIDS — POLYUNSATURATED (OMEGA-6)
Linoleic AcidLA; C18:2 n-6; Omega-6Lipids (Fatty Acid / Polyunsaturated)SunflowerHelianthus annuusSeed60-33-3HighAn essential omega-6 fatty acid required for normal skin barrier function, hormonal balance, and the body's inflammatory regulation.
Gamma-Linolenic AcidGLA; C18:3 n-6; Omega-6Lipids (Fatty Acid / Polyunsaturated)BorageBorago officinalisSeed506-26-3ModerateMay help support hormonal balance and healthy skin; studied for its role in modulating prostaglandin-mediated inflammatory pathways.
Arachidonic AcidAA; ARA; C20:4 n-6Lipids (Fatty Acid / Polyunsaturated)MossesPhyscomitrella patensWhole Plant506-32-1HighA key structural and signalling omega-6 fatty acid required for the synthesis of eicosanoids governing pain, sleep, and inflammatory balance.
Columbinic AcidC18:3 (5t,9c,12c)Lipids (Fatty Acid / Polyunsaturated)Meadow RueThalictrum aquilegifoliumSeedEmergingA rare trans-containing polyunsaturated fatty acid studied for potential structural and metabolic roles in lipid biology.
Mead AcidC20:3 n-9; 5,8,11-Eicosatrienoic acidLipids (Fatty Acid / Polyunsaturated)PrimroseOenothera spp.Seed20590-32-3EmergingProduced by the body when essential fatty acid intake is low; studied as a biomarker for evaluating omega-3 and omega-6 nutritional status.
Coriolic Acid13-Hydroxy-9,11-octadecadienoic acidLipids (Fatty Acid / Polyunsaturated)CoriariaCoriaria myrtifoliaSeedEmergingA hydroxy fatty acid studied in early-stage research for its potential to help modulate the body's inflammatory response.
FATTY ACIDS — POLYUNSATURATED (OMEGA-3)
alpha-Linolenic AcidALA; C18:3 n-3; Omega-3Lipids (Fatty Acid / Polyunsaturated)FlaxLinum usitatissimumSeed463-40-5ModerateA plant-source omega-3 fatty acid; may support cardiovascular health and normal inflammatory balance when consumed as part of a varied diet.
Stearidonic AcidSDA; C18:4 n-3; Omega-3Lipids (Fatty Acid / Polyunsaturated)HempCannabis sativaSeed20290-75-9ModerateAn omega-3 fatty acid that may convert to EPA more efficiently than ALA; studied for potential cardiovascular and inflammatory benefits.
Eicosapentaenoic AcidEPA; C20:5 n-3; Omega-3Lipids (Fatty Acid / Polyunsaturated)MicroalgaeNannochloropsis spp.Whole Cell10417-94-4HighPlays a well-documented role in supporting normal blood triglyceride levels and healthy inflammatory balance.
Docosapentaenoic AcidDPA; C22:5 n-3; Omega-3Lipids (Fatty Acid / Polyunsaturated)MicroalgaeSchizochytrium spp.Whole Cell53988-10-6ModerateA metabolic intermediate between EPA and DHA; studied for potential cardiovascular and neural health support.
Docosahexaenoic AcidDHA; C22:6 n-3; Omega-3Lipids (Fatty Acid / Polyunsaturated)MicroalgaeSchizochytrium spp.Whole Cell6217-54-5HighA critical omega-3 fatty acid required for normal brain development and the maintenance of healthy visual function throughout life.
Sciadonic AcidC20:3 n-6 (5,11,14-eicosatrienoic)Lipids (Fatty Acid / Polyunsaturated)Umbrella PineSciadopitys verticillataSeedEmergingA non-conventional polyunsaturated fatty acid studied for potential anti-inflammatory properties at the cardiovascular level.
FATTY ACIDS — CONJUGATED & SPECIALIZED
Punicic AcidTrichosanic acid; Omega-5 CLALipids (Fatty Acid / Conjugated)PomegranatePunica granatumSeed Oil544-72-9ModerateA conjugated omega-5 fatty acid studied for its potential to support healthy insulin sensitivity and metabolic balance.
Calendic AcidBeta-calendic acid; C18:3 (8t,10t,12c)Lipids (Fatty Acid / Conjugated)MarigoldCalendula officinalisSeedEmergingA conjugated fatty acid studied for antioxidant and mild anti-inflammatory properties; of interest for skin health applications.
Catalpic AcidC18:3 (9t,11t,13c)Lipids (Fatty Acid / Conjugated)Catalpa TreeCatalpa spp.SeedEmergingAn unusual trans-conjugated fatty acid studied for potential contributions to a healthy cardiovascular lipid profile.
Eleostearic AcidAlpha-eleostearic acid; C18:3 (9c,11t,13t)Lipids (Fatty Acid / Conjugated)Bitter GourdMomordica charantiaSeedEmergingStudied in laboratory settings for potential antiproliferative properties; early-stage research, not established in human studies.
Parinaric AcidAlpha-parinaric acid; C18:4 conj.Lipids (Fatty Acid / Conjugated)ParinariParinari curatellifoliaSeedEmergingA tetra-unsaturated conjugated fatty acid studied for its antioxidant potential and ability to protect cells from lipid peroxidation.
Jacaric AcidC18:3 (8c,10t,12c)Lipids (Fatty Acid / Conjugated)JacarandaJacaranda mimosifoliaSeedEmergingStudied in laboratory settings for potential proapoptotic activity against damaged or abnormal cells; early-stage research only.
Licanic Acid4-Keto-alpha-eleostearic acidLipids (Fatty Acid / Conjugated)OiticicaLicania rigidaSeedEmergingA keto-conjugated fatty acid studied for its potential role in supporting tissue healing and cellular recovery.
Pinolenic AcidDelta-5-linolenic acid; C18:3 (5c,9c,12c)Lipids (Fatty Acid / Specialized)Pine NutPinus sibiricaNut16833-54-8ModerateMay support appetite regulation by stimulating the release of satiety hormones; studied in the context of weight management.
Ricinoleic Acid12-Hydroxy-9-cis-octadecenoic acidLipids (Fatty Acid / Hydroxy)Castor BeanRicinus communisSeed141-22-0ModerateTraditionally used to support digestive regularity; studied for potential soothing properties on smooth muscle tissue.
Vernolic Acid12,13-Epoxy-9-octadecenoic acidLipids (Fatty Acid / Epoxy)IronweedVernonia galamensisSeedEmergingAn epoxy fatty acid being studied for potential applications in skin repair and high-performance wellness formulations.
Taxoleic AcidC18:2 (5c,9c)Lipids (Fatty Acid / Specialized)Yew TreeTaxus spp.SeedEmergingA non-conventional dienoic fatty acid studied for its contribution to healthy lipid diversity in cell membranes.
Juniperic Acid16-Hydroxyhexadecanoic acidLipids (Fatty Acid / Hydroxy)JuniperJuniperus spp.NeedlesEmergingA plant wax hydroxy fatty acid studied for its minor role in maintaining protective skin and cuticle resilience.
Sabinic Acid12-Hydroxydodecanoic acidLipids (Fatty Acid / Hydroxy)Savin JuniperJuniperus sabinaNeedlesEmergingA medium-chain hydroxy fatty acid studied as a structural building block for specialised cellular lipid functions.
Phloionolic Acid9,10,18-Trihydroxyoctadecanoic acidLipids (Fatty Acid / Polyhydroxy)Cork OakQuercus suberBarkEmergingA polyhydroxy fatty acid component of plant suberin; may contribute to the structural integrity of epithelial barrier tissues.
Lesquerolic Acid14-Hydroxyeicosenoic acidLipids (Fatty Acid / Hydroxy)Fendler's BladderpodLesquerella fendleriSeedEmergingStructurally similar to ricinoleic acid; studied for potential skin and joint health applications in wellness formulations.
Chaulmoogric AcidC18 cyclopentenyl fatty acidLipids (Fatty Acid / Cyclopentenyl)ChaulmoograHydnocarpus wightianusSeedModerateTraditionally used in Ayurvedic and herbal systems to support the body's defence against skin infections.
Hydnocarpic AcidC16 cyclopentenyl fatty acidLipids (Fatty Acid / Cyclopentenyl)ChaulmoograHydnocarpus wightianusSeedModerateWorks alongside chaulmoogric acid in traditional wellness applications for skin health and immune support.
Gorlic AcidC18 cyclopentenyl fatty acid (unsaturated)Lipids (Fatty Acid / Cyclopentenyl)ChaulmoograHydnocarpus wightianusSeedModerateA cyclopentenyl fatty acid in the chaulmoogra group; traditionally studied for supporting the body's response to external pathogens.
Malvalic Acid8-(2-Octylcyclopropenyl)octanoic acidLipids (Fatty Acid / Cyclopropene)CottonGossypium hirsutumSeedEmergingA cyclopropenoid fatty acid studied for its regulatory effects on fatty acid desaturation enzyme pathways.
Sterculic Acid9-(2-Octylcyclopropenyl)nonanoic acidLipids (Fatty Acid / Cyclopropene)Sterculia TreeSterculia foetidaSeedEmergingA cyclopropenoid fatty acid studied for its inhibitory interaction with stearoyl-CoA desaturase enzymes.
Cyclopropenoid Fatty AcidCyclopropene FA class; Sterculene-typeLipids (Fatty Acid / Cyclopropene)BaobabAdansonia digitataSeedEmergingA class of unusual cyclic fatty acids contributing to the unique lipid profile of certain tropical seed oils.
HYDROXY, EPOXY & POLYHYDROXY FATTY ACIDS
10-Hydroxy-Stearic Acid10-Hydroxystearic acidLipids (Fatty Acid / Hydroxy)Various PlantsN/AEvery CellEmergingStudied as a signalling intermediate in lipid inflammatory pathways; may contribute to healthy tissue repair processes.
9,10-Epoxy-Stearic AcidEpoxystearic acidLipids (Fatty Acid / Epoxy)Plant CuticleN/ASurfaceEmergingA cuticle wax component studied for its potential role in maintaining healthy epithelial and mucosal surface integrity.
18-Hydroxy-Oleic AcidLipids (Fatty Acid / Hydroxy)PotatoSolanum tuberosumSkinEmergingA suberin-component hydroxy fatty acid studied for its contribution to the structural repair of the body's outer protective barriers.
16-Hydroxy-Palmitic AcidDihydroxypalmitic acid (partial)Lipids (Fatty Acid / Hydroxy)AppleMalus domesticaFruit PeelEmergingA plant wax hydroxy fatty acid studied for its potential role in supporting protective skin moisture retention.
9,10,18-Trihydroxy-Stearic AcidPhloionolic acid (related form)Lipids (Fatty Acid / Polyhydroxy)SpinachSpinacia oleraceaLeavesEmergingA polyhydroxy fatty acid studied for its potential contribution to gut mucosal health and digestive microbiome balance.
VERY LONG-CHAIN SATURATED FATTY ACIDS
Heneicosanoic AcidC21:0Lipids (Fatty Acid / Very Long Chain)Various PlantsN/ASeedsEmergingA rare odd-chain saturated fatty acid; studied as a dietary biomarker and contributor to fatty acid structural diversity.
Tricosanoic AcidC23:0Lipids (Fatty Acid / Very Long Chain)LegumesN/ASeedsEmergingAn odd-chain saturated fatty acid that may contribute to the structural complexity of human cell membranes.
Pentacosanoic AcidC25:0Lipids (Fatty Acid / Very Long Chain)Various GrainsN/ASeedsEmergingMay support long-term energy metabolism and contribute to the structural health of nerve tissue.
Heptacosanoic AcidC27:0Lipids (Fatty Acid / Very Long Chain)Tree WaxesN/ALeavesEmergingA plant wax fatty acid that contributes to the diversity of very long-chain lipids in the human diet.
Nonacosanoic AcidC29:0Lipids (Fatty Acid / Very Long Chain)Sugarcane WaxSaccharum officinarumStemEmergingA wax-derived fatty acid studied for its minor contribution to healthy lipid and energy balance.
Hentriacontanoic AcidC31:0Lipids (Fatty Acid / Very Long Chain)Plant WaxesN/ALeavesEmergingA very long-chain wax fatty acid that may support the integrity and protective function of the skin barrier.
Tritriacontanoic AcidC33:0Lipids (Fatty Acid / Very Long Chain)Tropical WaxesN/ASurfaceEmergingA rare wax fatty acid contributing to the structural stability of specialised plant wax complexes.
Pentatriacontanoic AcidC35:0Lipids (Fatty Acid / Very Long Chain)Rare Tree OilsN/ASeedsEmergingA trace very long-chain lipid playing a minor structural role in overall cellular and membrane stability.
FATTY ALCOHOLS & WAX ALCOHOLS
Eicosanol1-Eicosanol; C20 fatty alcoholLipids (Fatty Alcohol / Wax)Sesame OilSesamum indicumSeedModerateA plant wax primary alcohol studied for its potential to support skin tissue health and recovery in topical applications.
DocosanolBehenyl alcohol; C22 fatty alcoholLipids (Fatty Alcohol / Wax)Peanut OilArachis hypogaeaSeed661-19-8ModerateA long-chain fatty alcohol with studied antiviral properties; clinically investigated for managing labial viral infections.
TetracosanolLignoceryl alcohol; C24 fatty alcoholLipids (Fatty Alcohol / Wax)Rice BranOryza sativaBranModerateA plant wax component studied for its potential contribution to protecting nervous system tissues from oxidative stress.
HexacosanolCeryl alcohol; C26 fatty alcoholLipids (Fatty Alcohol / Wax)Sugar CaneSaccharum officinarumStemModerateA constituent of policosanol wax mixtures studied for potential heart-supportive properties in cholesterol management.
Octacosanol1-Octacosanol; C28 fatty alcoholLipids (Fatty Alcohol / Wax)Wheat GermTriticum aestivumSeed557-61-9ModerateStudied for potential benefits to exercise performance and endurance; may support healthy cholesterol balance.
TriacontanolMelissyl alcohol; C30 fatty alcoholLipids (Fatty Alcohol / Wax)AlfalfaMedicago sativaLeaves593-50-0ModerateA natural plant wax alcohol studied for potential support of metabolic vitality and physical energy levels.
Hexadecanediol1,16-HexadecanediolLipids (Fatty Alcohol / Wax)Various PlantsN/ASurfaceEmergingA diol wax component that may contribute to the stability and protective moisture function of skin barrier layers.
PhytolPhytyl alcohol; Diterpene alcoholLipids (Diterpene Alcohol)All Green LeavesN/AChloroplast150-86-7ModerateA chlorophyll breakdown product that serves as a biosynthetic precursor to Vitamins E and K in the body.
Phytanic Acid3,7,11,15-Tetramethylhexadecanoic acidLipids (Fatty Acid / Branched)SpinachSpinacia oleraceaLeavesModerateA branched-chain fatty acid derived from dietary phytol; studied for its role in managing fat and glucose metabolism.
Pristanic Acid2,6,10,14-Tetramethylpentadecanoic acidLipids (Fatty Acid / Branched)Green VegetablesN/ALeavesEmergingA branched-chain metabolite of phytanic acid; may contribute to the healthy metabolic function of liver cells.
PHOSPHOLIPIDS & LYSOPHOSPHOLIPIDS
PhosphatidylcholineLecithin; PCLipids (Phospholipid)SoybeanGlycine maxSeed8002-43-5HighA major dietary source of choline, supporting liver function, cognitive health, and the structural integrity of all cell membranes.
PhosphatidylethanolamineCephalin; PELipids (Phospholipid)Wheat GermTriticum aestivumSeedModerateSupports the structural integrity of brain cell membranes and may contribute to healthy neurotransmitter signalling.
PhosphatidylinositolPILipids (Phospholipid)CornZea maysGrainsModeratePlays a central role in insulin signalling and intracellular communication; may support healthy glucose response.
PhosphatidylserinePS; Soy PSLipids (Phospholipid)SoybeanGlycine maxSeed51446-62-9ModerateStudied for supporting cognitive performance and age-related memory health; limited human trial data available.
PhosphatidylglycerolPGLipids (Phospholipid)SpinachSpinacia oleraceaLeavesModerateAn essential component of lung surfactant; may contribute to healthy respiratory function and airway surface integrity.
CardiolipinBisphosphatidylglycerol; CLLipids (Phospholipid)All Green PlantsN/AEvery CellHighA mitochondria-specific phospholipid critical for cellular energy production efficiency and metabolic function.
Lyso-PhosphatidylcholineLPC; Lyso-PCLipids (Phospholipid)Various PlantsN/AEvery CellModerateInvolved in lipid signalling pathways; studied for its role in regulating the body's tissue healing and inflammatory response.
Lyso-PhosphatidylethanolamineLPE; Lyso-PELipids (Phospholipid)Various PlantsN/AEvery CellEmergingStudied as a bioactive signalling lipid involved in healthy cellular maturation and membrane renewal processes.
N-Acyl-PhosphatidylethanolamineNAPELipids (Phospholipid)CottonseedGossypium hirsutumSeedModerateA lipid signalling precursor that may communicate satiety signals to the brain in response to food intake.
N-AcylethanolamineNAE; Endocannabinoid-related lipidLipids (Phospholipid)SoybeanGlycine maxSeedModerateMay support the body's natural stress-modulating system; studied for potential contribution to a calm physiological state.
Phosphatidic AcidPALipids (Phospholipid)All PlantsN/AEvery CellModerateA key lipid signalling molecule studied for its potential role in supporting muscle protein synthesis and post-exercise recovery.
GALACTOLIPIDS & SULFOLIPIDS
MonogalactosyldiacylglycerolMGDGLipids (Galactolipid)Dog RoseRosa caninaFruit (Hips)ModerateThe most abundant plant membrane lipid; studied for potential anti-inflammatory effects with relevance to joint health support.
DigalactosyldiacylglycerolDGDGLipids (Galactolipid)SpinachSpinacia oleraceaLeavesModerateA plant-source galactolipid that may help modulate inflammatory responses and support healthy immune balance.
SulfoquinovosyldiacylglycerolSQDG; Plant SulfolipidLipids (Sulfolipid)Sea LettuceUlva lactucaWhole PlantEmergingA sulfonated glycolipid studied for potential antiviral properties and its role in supporting detoxification pathways.
Acylated-MGDGAcyl-MGDGLipids (Galactolipid)ArabidopsisArabidopsis thalianaLeavesEmergingStudied for its role in lipid remodelling during cellular stress and its potential contribution to wound-healing signalling.
TRIACYLGLYCEROLS
TrioleinGlyceryl trioleateLipids (Triacylglycerol)Olive TreeOlea europaeaFruitModerateThe predominant triacylglycerol of olive oil; may support heart health by providing monounsaturated fats as part of a balanced diet.
TrilinoleinGlyceryl trilinoleateLipids (Triacylglycerol)Evening PrimroseOenothera biennisSeedModerateA source of essential linoleic acid that may support healthy skin, hair, and nail integrity.
PLANT STEROLS & STANOLS
Beta-sitosterolBeta-Sitosterol; 24-EthylcholesterolLipids (Sterol)Wheat GermTriticum aestivumSeed83-46-5HighCompetes with cholesterol for intestinal absorption; well-supported for helping maintain healthy blood cholesterol levels.
StigmasterolLipids (Sterol)SoybeanGlycine maxSeed83-48-7ModerateMay contribute to healthy cholesterol balance; studied as a biosynthetic base for steroid hormones.
Campesterol24-MethylcholesterolLipids (Sterol)RapeseedBrassica napusSeed474-62-4ModerateMay support cardiovascular health by contributing to a healthy blood lipid profile.
Brassicasterol24-Methyl-delta5,22-cholestadienolLipids (Sterol)BroccoliBrassica oleraceaFlorets474-67-9ModerateA Brassica-specific phytosterol that may contribute to a healthy overall lipid profile.
CycloartenolLipids (Sterol)Rice BranOryza sativaSeed Coat469-38-5ModerateA tetracyclic sterol and biosynthetic precursor to other plant sterols; studied for potential antioxidant properties.
SpinasterolLipids (Sterol)SpinachSpinacia oleraceaLeavesModerateA plant-specific sterol studied for its potential role in supporting healthy cholesterol metabolism.
SchottenolLipids (Sterol)Prickly PearOpuntia ficus-indicaSeedsModerateStudied for its potential to support healthy lipid-clearing metabolic pathways.
LophenolLipids (Sterol)Aloe VeraAloe veraLeavesModerateStudied for its potential to help maintain healthy blood sugar balance and support weight management.
ErgosterolProvitamin D2Lipids (Sterol)Button MushroomAgaricus bisporusFruit Body57-87-4HighA sterol precursor that converts to Vitamin D2 on UV exposure; important for bone health and immune system support.
SitostanolBeta-Sitostanol; 24-EthylcholestanolLipids (Stanol)CornZea maysBran19044-59-2HighOne of the most effective plant-derived compounds for blocking intestinal absorption of dietary cholesterol.
Campestanol24-MethylcholestanolLipids (Stanol)OatsAvena sativaGrains474-60-2HighMay provide a synergistic sterol-lowering effect when combined with other plant sterols to support heart health.
24-Methylene-CycloartanolLipids (Sterol)Rice Bran OilOryza sativaSeed CoatModerateA cycloartenol derivative studied for potential metabolic and cell-protective properties.
Sitosteryl FerulateBeta-Sitosteryl ferulate; Oryzanol componentLipids (Sterol Ester)Rice Bran OilOryza sativaBranModerateA phytosterol-ferulic acid conjugate studied for potential antioxidant and anti-inflammatory properties.
Delta-5-Avenasteroldelta5-AvenasterolLipids (Sterol)OatsAvena sativaGrainsModerateMay contribute to antioxidant protection of the cardiovascular system and support healthy lipid balance.
Delta-7-Avenasteroldelta7-AvenasterolLipids (Sterol)Sunflower OilHelianthus annuusSeedModerateMay support healthy vascular function and contribute to the maintenance of normal blood vessel resilience.
GramisterolLipids (Sterol)Wheat Germ OilTriticum aestivumSeedModerateA minor grain sterol that may support normal immune function and healthy lipid metabolism.
CitrostadienolLipids (Sterol)Citrus OilCitrus limonPeelModerateA minor phytosterol that may contribute to healthy metabolic rate and balanced lipid function.
Isofucosteroldelta5-Avenasterol (algal/oat form)Lipids (Sterol)Oat BranAvena sativaGrain HullModerateMay support healthy management of dietary fat absorption and contribute to energy regulation.
CycloartanolLipids (Sterol)Rice BranOryza sativaBranModerateA cyclopropane-containing sterol that may contribute to overall metabolic efficiency and cellular vitality.
24-Ethylidene-LophenolLipids (Sterol)TobaccoNicotiana tabacumLeavesEmergingStudied as a minor sterol; may provide structural components for healthy nerve membrane architecture.
STEROL ESTERS & GLYCOSIDES
Sitosteryl GlucosideBeta-Sitosteryl-3-O-glucosideLipids (Sterol Glucoside)TomatoSolanum lycopersicumFruitModerateStudied for its potential to support cellular adaptation to physical stress and environmental metabolic changes.
Acylated Steryl GlucosideASGLipids (Sterol Glucoside)PotatoSolanum tuberosumTuberModerateMay provide long-term structural support for healthy cell membrane architecture and function.
Sitosterol-PalmitateBeta-Sitosteryl palmitateLipids (Sterol Ester)Soybean OilGlycine maxSeed OilModerateA sterol ester form that may contribute to maintaining healthy cholesterol levels over time.
Campesterol-OleateCampesteryl oleateLipids (Sterol Ester)Corn OilZea maysSeed OilModerateMay support a balanced cardiovascular lipid profile and contribute to healthy blood flow.
Stigmasterol-LinoleateStigmasteryl linoleateLipids (Sterol Ester)Rapeseed OilBrassica napusSeed OilModerateContributes to the body's supply of essential fats alongside plant-based growth-supportive sterols.
TRITERPENOIDS (PENTACYCLIC)
Ursolic AcidUrson; Prunol; MalolLipids (Triterpenoid)AppleMalus domesticaFruit Peel77-52-1ModerateMay support the preservation of muscle mass and contribute to healthy metabolic balance; studied in fitness and nutrition contexts.
Oleanolic AcidCaryophyllinLipids (Triterpenoid)Olive TreeOlea europaeaLeaves508-02-1ModerateMay support liver health and help maintain the body's natural defence against certain microbial challenges.
Betulinic Acid3-beta-Hydroxy-lup-20(29)-en-28-oic acidLipids (Triterpenoid)Birch TreeBetula spp.Bark472-15-1EmergingStudied in laboratory settings for potential antiviral and antiproliferative properties; early-stage research only.
LupeolFagarasterol; Monogynol BLipids (Triterpenoid)MangoMangifera indicaFruit Peel545-47-1ModerateStudied for potential anti-inflammatory and skin-protective properties; some evidence for photoprotective effects on skin cells.
FriedelinLipids (Triterpenoid)Cork OakQuercus suberBark559-74-0ModerateExhibits potential anti-inflammatory and analgesic properties; traditionally used in topical skin-healing applications.
ErythrodiolLipids (Triterpenoid)Olive OilOlea europaeaFruitModerateA pentacyclic triterpenoid that may contribute to the overall antioxidant properties of olive-based diets.
UvaolLipids (Triterpenoid)BearberryArctostaphylos uva-ursiLeavesModerateTraditionally associated with urinary tract health support; studied for potential anti-inflammatory properties.
TaraxerolLipids (Triterpenoid)DandelionTaraxacum officinaleRoots4066-83-5ModerateStudied for potential liver-supportive and detoxification-promoting properties in traditional herbal wellness.
TaraxasterolLipids (Triterpenoid)DandelionTaraxacum officinaleFlowersModerateStudied for potential anti-inflammatory properties that may support joint and connective tissue health.
BetulinBetulinol; BetulolLipids (Triterpenoid)Birch TreeBetula spp.Bark473-98-3ModerateA major birch bark constituent studied for potential contributions to skin healing and immune defence support.
SQUALENE
SqualeneSpinacene; Supraene; C30 triterpeneLipids (Terpene / Triterpene)Olive OilOlea europaeaFruit111-02-4ModerateA natural triterpene emollient that may support skin hydration; studied for potential immune-modulating properties.
SPHINGOLIPIDS
Phytosphingosine4-Hydroxysphinganine; t18:0Lipids (Sphingolipid)RiceOryza sativaGrains554-62-1ModerateStudied for its antimicrobial properties in skincare applications; may help support a healthy skin barrier.
GlucosylceramideGlcCer; Plant Ceramide GlucosideLipids (Sphingolipid)WheatTriticum aestivumGrainsModerateOral supplementation has been studied for its potential to improve skin hydration from within the body.
CeramideN-Acylsphingosine (class)Lipids (Sphingolipid)SoybeanGlycine maxSeedModerateStudied for its role in restoring the skin's protective barrier and reducing transepidermal water loss.
Mannosyl-Inositol-PhosphoceramideMIPCLipids (Sphingolipid)TomatoSolanum lycopersicumLeavesEmergingA complex sphingolipid studied for plant immune recognition; early-stage research into relevance for human cellular health.
Phytosphingosine-1-PhosphatePhS1PLipids (Sphingolipid)ArabidopsisArabidopsis thalianaLeavesEmergingA lipid signalling molecule associated with cellular survival signalling and healthy growth regulation.
Ceramide-1-PhosphateC1PLipids (Sphingolipid)Various PlantsN/AEvery CellEmergingA bioactive lipid mediator studied for its signalling role in cellular repair and growth in response to physiological stimuli.
GIPC (Plant Sphingolipid)Glycosyl Inositol PhosphoceramideLipids (Sphingolipid)SoybeanGlycine maxSeedModerateThe most abundant plant sphingolipid class; studied for potential contributions to maintaining healthy cellular cholesterol balance.
Mannosyl-GIPCLipids (Sphingolipid)TomatoSolanum lycopersicumLeavesEmergingStudied for plant immune recognition roles; early-stage research into relevance for human gut microbiome interactions.
Arabinosyl-GIPCLipids (Sphingolipid)LegumesN/ARootsEmergingMay contribute to gut microbiome diversity through its structural role in plant cell membranes; early-stage research.
Galactosyl-GIPCLipids (Sphingolipid)Various PlantsN/AEvery CellEmergingA structural sphingolipid studied for its potential role in supporting healthy cell membrane communication.
Xylosyl-GIPCLipids (Sphingolipid)Plant MembranesN/ACellEmergingA minor sphingolipid class studied for its relevance to the structural resilience of plant and human cell membranes.
Fucosyl-GIPCLipids (Sphingolipid)Plant MembranesN/ACellEmergingPlays a role in the structural complexity of plant sphingolipid profiles; studied for relevance to human cell biology.
STORAGE PROTEINS — GLOBULINS
Glycinin11S Globulin; Soy GlobulinProtein (Globulin)SoybeanGlycine maxSeedHighA well-studied complete protein providing all essential amino acids; may support muscle maintenance and bone density.
Beta-Conglycinin7S Globulin; Soy 7SProtein (Globulin)SoybeanGlycine maxSeedModerateMay contribute to healthy blood lipid balance and support normal glucose metabolism as part of a soy-rich diet.
Phaseolin7S Vicilin; Bean GlobulinProtein (Globulin)Kidney BeanPhaseolus vulgarisSeedModerateProvides essential amino acids for cell repair; may contribute to satiety when consumed as part of a high-protein diet.
Vicilin7S Globulin; Pea Storage ProteinProtein (Globulin)Garden PeaPisum sativumSeedModerateA well-digestible plant protein that may support general growth, tissue maintenance, and physical recovery.
Legumin11S Globulin; Pea LeguminProtein (Globulin)Broad BeanVicia fabaSeedModerateSupplies a broad spectrum of amino acids; may support immune cell production and overall physical maintenance.
Amandin11S Globulin; Almond ProteinProtein (Globulin)AlmondPrunus dulcisNut KernelModerateThe primary storage protein of almonds; may support heart health and muscle tissue maintenance as part of a nut-rich diet.
EdestinCannabis Globulin; Hemp 11SProtein (Globulin)HempCannabis sativaSeedModerateA highly bioavailable plant globulin; studied for potential immune-supportive properties due to its structural similarity to human blood proteins.
Cruciferin12S Globulin; Brassica Storage ProteinProtein (Globulin)MustardSinapis albaSeedModerateA Brassica storage protein providing essential amino acids that may support normal tissue repair and regeneration.
Excelsin11S Globulin; Brazil Nut ProteinProtein (Globulin)Brazil NutBertholletia excelsaNut KernelModerateRich in selenium-containing amino acids; may support thyroid health and contribute to the antioxidant defence system.
CorylinHazelnut GlobulinProtein (Globulin)HazelnutCorylus avellanaNut KernelModerateA nut storage protein providing essential fatty acid-associated amino acids; may support brain function and metabolic health.
JuglansinWalnut 11S GlobulinProtein (Globulin)WalnutJuglans regiaNut KernelModerateProvides essential amino acids alongside heart-healthy fats; may support healthy aging and cognitive function.
CocosinCoconut GlobulinProtein (Globulin)CoconutCocos nuciferaEndospermModerateA coconut storage protein studied for its potential to support energy levels and healthy fat metabolism.
VigninMung Bean Globulin; 8S GlobulinProtein (Globulin)Mung BeanVigna radiataSeedModerateA highly digestible legume protein that may support muscle repair and is generally well-tolerated by the digestive system.
CicerinChickpea GlobulinProtein (Globulin)ChickpeaCicer arietinumSeedModerateA satiating plant protein that may support healthy weight management and appetite regulation.
LininFlaxseed GlobulinProtein (Globulin)FlaxseedLinum usitatissimumSeedModerateMay work synergistically with flaxseed's omega-3 fats to support heart health and hormonal balance.
ConglutinLupin Globulin; alpha-ConglutinProtein (Globulin)LupinLupinus spp.SeedModerateA high-protein legume fraction that may help support healthy post-meal blood sugar levels.
STORAGE PROTEINS — PROLAMINS
GliadinWheat Prolamin; alpha/beta/gamma-GliadinProtein (Prolamin)WheatTriticum aestivumGrain EndospermHighA wheat storage protein that provides dietary nitrogen; responsible for the viscoelastic properties of gluten. Note: implicated in coeliac disease in susceptible individuals.
GluteninHigh/Low MW Glutenin; HMW-GSProtein (Glutelin)WheatTriticum aestivumGrain EndospermHighThe glutelin fraction of gluten that contributes to dough strength; provides a structural protein matrix for sustained carbohydrate energy release.
ZeinCorn Prolamin; alpha/beta/gamma-ZeinProtein (Prolamin)Maize (Corn)Zea maysGrain EndospermModerateA gluten-free grain protein providing specific amino acid components for cellular energy production and structural support.
HordeinBarley Prolamin; B/C/D-HordeinProtein (Prolamin)BarleyHordeum vulgareGrain EndospermModerateA barley storage protein that contributes to metabolic support; may cause sensitivity in gluten-intolerant individuals.
SecalinRye Prolamin; gamma-SecalinProtein (Prolamin)RyeSecale cerealeGrain EndospermModerateA rye storage protein that contributes to dietary protein intake; may cause sensitivity in coeliac or gluten-sensitive individuals.
AveninOat ProlaminProtein (Prolamin)OatsAvena sativaGrain EndospermModerateA gentle, well-tolerated oat protein that may contribute to heart health and muscle recovery when consumed as part of a balanced diet.
KafirinSorghum Prolamin; alpha/beta-KafirinProtein (Prolamin)SorghumSorghum bicolorGrain EndospermModerateA gluten-free grain protein that provides a hypoallergenic protein source and may support healthy metabolic function.
STORAGE PROTEINS — GLUTELINS & ALBUMINS
OryzeninRice Glutelin; Rice ProteinProtein (Glutelin)RiceOryza sativaGrain EndospermModerateA hypoallergenic, easily digestible plant protein that may support muscle maintenance without triggering common grain allergies.
Napin2S Albumin; Rapeseed 2SProtein (Albumin)Rapeseed / CanolaBrassica napusSeedModerateA sulfur-rich small storage protein; may provide cysteine and methionine for healthy skin, hair, and antioxidant defence.
LunasinBioactive Soy Peptide; 2S Albumin fragmentProtein (Albumin)SoybeanGlycine maxSeedModerateA bioactive peptide studied for potential anti-inflammatory properties and support of healthy cell cycle regulation.
LeukosinWheat Albumin; WGA-relatedProtein (Albumin)WheatTriticum aestivumGrainModerateA water-soluble wheat protein that contributes to the overall nutritional value of whole-wheat foods.
LegumelinSoy Albumin fractionProtein (Albumin)SoybeanGlycine maxSeedModerateSupplies essential amino acids for daily cellular repair and growth as part of a complete plant protein diet.
LECTINS
Concanavalin ACon A; Jack Bean LectinProtein (Lectin)Jack BeanCanavalia ensiformisSeedModerateA well-characterised mitogenic lectin widely used in immunological research to study T-cell activation and immune surveillance.
Wheat Germ AgglutininWGAProtein (Lectin)WheatTriticum aestivumGermModerateA chitin-binding lectin studied for its interaction with gut epithelial surfaces; subject of ongoing research into digestive health effects.
PROTEASE ENZYMES (HYDROLASES)
PapainPapaya Protease; EC 3.4.22.2Enzyme (Hydrolase / Protease)PapayaCarica papayaFruit (Latex)HighEffectively breaks down dietary proteins to support comfortable digestion; may help reduce post-meal bloating and digestive discomfort.
BromelainPineapple Protease; EC 3.4.22.32Enzyme (Hydrolase / Protease)PineappleAnanas comosusFruit and StemHighMay support reduction of localised swelling and discomfort; studied for its role in aiding digestion of protein-rich foods.
ActinidinKiwifruit Protease; EC 3.4.22.14Enzyme (Hydrolase / Protease)KiwifruitActinidia deliciosaFruitModerateStudied for its ability to specifically improve digestion of proteins from meat, eggs, and dairy, potentially improving gut comfort.
FicinFig Protease; EC 3.4.22.3Enzyme (Hydrolase / Protease)FigFicus caricaFruit (Latex)ModerateA plant cysteine protease that may aid in protein digestion and has been studied for potential soothing effects in the gut.
CARBOHYDRASE ENZYMES (HYDROLASES)
Alpha-Amylase1,4-alpha-D-glucan glucanohydrolase; EC 3.2.1.1Enzyme (Hydrolase / Carbohydrase)MangoMangifera indicaFruitHighCatalyses the hydrolysis of dietary starch into shorter oligosaccharides, supporting efficient carbohydrate digestion and energy availability.
Beta-Amylase1,4-alpha-D-glucan maltohydrolase; EC 3.2.1.2Enzyme (Hydrolase / Carbohydrase)Sweet PotatoIpomoea batatasTuberModerateSlowly releases maltose from starch; may support a more gradual and sustained release of glucose into the bloodstream.
CellulaseEC 3.2.1.4Enzyme (Hydrolase / Carbohydrase)SproutsMedicago sativaWhole SproutModerateMay assist in breaking down plant cell wall fibers, potentially reducing bloating and improving regularity.
InvertaseBeta-fructofuranosidase; EC 3.2.1.26Enzyme (Hydrolase / Carbohydrase)Honey (via Pollen)N/APollen / NectarModerateConverts sucrose into glucose and fructose, providing rapidly available cellular energy.
PectinasePolygalacturonase (class); EC 3.2.1.15Enzyme (Hydrolase / Carbohydrase)AppleMalus domesticaFruitModerateBreaks down pectin in plant cell walls; may improve bioavailability of vitamins and minerals from plant foods.
MaltaseAlpha-glucosidase; EC 3.2.1.20Enzyme (Hydrolase / Carbohydrase)BananaMusa acuminataFruitHighCompletes the digestion of maltose into glucose at the intestinal brush border, supporting steady energy supply.
SucraseBeta-fructosidase; EC 3.2.1.48Enzyme (Hydrolase / Carbohydrase)SugarcaneSaccharum officinarumStem JuiceHighHydrolyses dietary sucrose to glucose and fructose; essential for normal carbohydrate digestion and energy metabolism.
Alpha-GalactosidaseEC 3.2.1.22Enzyme (Hydrolase / Carbohydrase)BeansPhaseolus spp.SeedModerateMay reduce the production of gas and bloating from consuming high-fiber legumes by breaking down indigestible oligosaccharides.
Beta-GlucosidaseEC 3.2.1.21Enzyme (Hydrolase / Carbohydrase)AlmondsPrunus dulcisNutModerateUnlocks bioactive aglycone compounds from plant glycosides, potentially improving their availability for health support.
GlucanaseEC 3.2.1.6Enzyme (Hydrolase / Carbohydrase)BarleyHordeum vulgareGrainModerateBreaks down beta-glucan fibers; may support the release of heart-healthy fiber fractions from cereal grains.
XylanaseEC 3.2.1.8Enzyme (Hydrolase / Carbohydrase)Oat BranAvena sativaGrainModerateMay aid in the breakdown of tough hemicellulose fibers from whole grains, improving digestive comfort.
HemicellulaseEC 3.2.1 (class)Enzyme (Hydrolase / Carbohydrase)Whole GrainsVariousSeed CoatModerateBreaks down complex hemicellulose polysaccharides to release prebiotic fragments that feed beneficial gut bacteria.
Alpha-GlucosidaseEC 3.2.1.20Enzyme (Hydrolase / Carbohydrase)BuckwheatFagopyrum esculentumSeedModeratePlays a key role in the final hydrolysis of starch at the intestinal surface; inhibition of this enzyme is a studied approach to blood sugar management.
PolygalacturonaseEC 3.2.1.15Enzyme (Hydrolase / Carbohydrase)TomatoSolanum lycopersicumFruitModerateA fruit-ripening enzyme that breaks down pectin, improving the bioavailability of antioxidants and beneficial plant pigments.
Pectin MethylesteraseEC 3.1.1.11Enzyme (Hydrolase / Carbohydrase)OrangeCitrus sinensisFruitModerateWorks alongside pectinase to support the healthy breakdown of fruit fiber; may contribute to normal digestive tract function.
MyrosinaseThioglucosidase; EC 3.2.1.147Enzyme (Hydrolase / Carbohydrase)BroccoliBrassica oleraceaFloretsHighActivates glucosinolate hydrolysis to produce bioactive compounds including sulforaphane; requires intact plant tissue for activity.
LactaseBeta-galactosidase; EC 3.2.1.23Enzyme (Hydrolase / Carbohydrase)Fermented SoyGlycine maxBean (Fermented)HighHydrolyses lactose into glucose and galactose; supplementation may support digestive comfort in lactose-sensitive individuals.
PhytaseEC 3.1.3.8Enzyme (Hydrolase / Carbohydrase)Wheat BranTriticum aestivumOuter LayerModerateHydrolyses phytic acid in cereal grains, potentially improving the bioavailability of minerals such as iron, zinc, and calcium.
UreaseEC 3.5.1.5Enzyme (Hydrolase)Jack BeanCanavalia ensiformisSeedModerateCatalyses the hydrolysis of urea; studied for its role in nitrogen metabolism and efficient protein utilisation.
AsparaginaseL-Asparaginase; EC 3.5.1.1Enzyme (Hydrolase)AsparagusAsparagus officinalisSpearsModerateBreaks down asparagine in plant foods; studied for its role in supporting healthy cell cycle dynamics.
ArginaseEC 3.5.3.1Enzyme (Hydrolase)SoybeanGlycine maxSeedModerateCatalyses the final step of the urea cycle, helping the liver process nitrogen waste from dietary protein.
LIPASE ENZYMES (HYDROLASES)
LipaseTriacylglycerol lipase; EC 3.1.1.3Enzyme (Hydrolase / Lipase)AvocadoPersea americanaFruitHighCatalyses the hydrolysis of dietary fats into fatty acids and glycerol, supporting absorption of fat-soluble vitamins and essential fats.
OXIDOREDUCTASE ENZYMES
Superoxide DismutaseSOD; EC 1.15.1.1Enzyme (Oxidoreductase)WheatgrassTriticum aestivumYoung LeavesHighA primary cellular antioxidant enzyme that dismutates superoxide radicals; studied for its role in supporting healthy aging and oxidative stress management.
CatalaseEC 1.11.1.6Enzyme (Oxidoreductase)PotatoSolanum tuberosumTuberHighNeutralises hydrogen peroxide produced in metabolic processes, protecting cells and tissues from oxidative damage.
PeroxidaseEC 1.11.1Enzyme (Oxidoreductase)HorseradishArmoracia rusticanaRootModerateSupports the body's oxidative defence pathways; studied for its role in detoxification and immune system function.
Polyphenol OxidasePPO; Tyrosinase (plant); EC 1.10.3.1Enzyme (Oxidoreductase)BananaMusa acuminataFruitModerateInvolved in phenolic compound oxidation during ripening; studied for its role in making antioxidant plant compounds more bioavailable.
LipoxygenaseLOX; EC 1.13.11.12Enzyme (Oxidoreductase)SoybeanGlycine maxSeedModerateMetabolises polyunsaturated fatty acids to produce oxylipins; plays a regulatory role in cell membrane integrity and inflammatory balance.
Ascorbate PeroxidaseAPX; EC 1.11.1.11Enzyme (Oxidoreductase)SpinachSpinacia oleraceaLeavesModerateWorks in concert with Vitamin C to neutralise hydrogen peroxide; may contribute to the antioxidant capacity of green leafy vegetable consumption.
Glucose OxidaseGOx; EC 1.1.3.4Enzyme (Oxidoreductase)Honey (via Nectar)N/ANectarModerateProduces hydrogen peroxide as a by-product; studied for its potential contribution to maintaining a healthy microbial balance in fermented foods.
Glutathione PeroxidaseGPx; EC 1.11.1.9Enzyme (Oxidoreductase)GarlicAllium sativumBulbHighA selenium-dependent antioxidant enzyme that protects cells from lipid peroxidation and supports healthy detoxification of heavy metals.
Ascorbate OxidaseEC 1.10.3.3Enzyme (Oxidoreductase)CucumberCucumis sativusFruitModerateRegulates the oxidation state of ascorbic acid in plant tissues; studied for its interaction with Vitamin C metabolism.
TyrosinaseEC 1.14.18.1Enzyme (Oxidoreductase)Button MushroomAgaricus bisporusFruit BodyModerateInvolved in melanin biosynthesis and phenolic compound processing; studied for its role in skin health and general metabolic regulation.
NitrogenaseEC 1.18.6.1Enzyme (Oxidoreductase)PeasPisum sativumRootsHighThe enzyme responsible for biological nitrogen fixation in legume root nodules; the foundational source of bioavailable nitrogen in plant-based protein foods.
Lactate DehydrogenaseLDH; EC 1.1.1.27Enzyme (Oxidoreductase)PeasPisum sativumSeedModerateInterconverts lactate and pyruvate; studied for its role in supporting muscle endurance and anaerobic energy metabolism.
Malate DehydrogenaseMDH; EC 1.1.1.37Enzyme (Oxidoreductase)AppleMalus domesticaFruitModerateA key enzyme of the citric acid cycle linking malate and oxaloacetate; central to maintaining cellular energy production.
Succinate DehydrogenaseSDH; EC 1.3.5.1Enzyme (Oxidoreductase)MilletPanicum miliaceumSeedModerateA membrane-bound enzyme at the intersection of the citric acid cycle and the electron transport chain; important for efficient mitochondrial energy generation.
Alcohol DehydrogenaseADH; EC 1.1.1.1Enzyme (Oxidoreductase)OrangeCitrus sinensisFruitModerateCatalyses the interconversion of alcohols and aldehydes; plays a role in the detoxification of naturally occurring organic compounds.
Glutamate DehydrogenaseGDH; EC 1.4.1.2Enzyme (Oxidoreductase)PeanutsArachis hypogaeaSeedModeratePlays a central role in amino acid catabolism and the integration of protein and carbohydrate metabolism for energy balance.
Nitrate ReductaseNR; EC 1.7.1.1Enzyme (Oxidoreductase)BeetrootBeta vulgarisRootModerateReduces dietary nitrate to nitrite, which the body further converts to nitric oxide; may support healthy blood pressure and circulation.
Glyceraldehyde-3-P DehydrogenaseGAPDH; EC 1.2.1.12Enzyme (Oxidoreductase)KaleBrassica oleraceaLeavesHighA central glycolytic enzyme that catalyses the conversion of glyceraldehyde-3-phosphate and directly releases energy from dietary sugars.
Malic EnzymeME; EC 1.1.1.40Enzyme (Oxidoreductase)AppleMalus domesticaFruitModerateCatalyses the oxidative decarboxylation of malate; studied for its role in supporting the biosynthesis of healthy fats and NADPH generation.
Glutathione ReductaseGR; EC 1.8.1.7Enzyme (Oxidoreductase)SpinachSpinacia oleraceaLeavesHighRegenerates reduced glutathione from its oxidised form, maintaining the body's primary antioxidant defence and cellular redox balance.
Thioredoxin ReductaseTrxR; EC 1.8.1.9Enzyme (Oxidoreductase)Wheat GermTriticum aestivumGermModerateMaintains the thioredoxin system, which plays a key role in DNA repair, antioxidant defence, and cellular stress responses.
Homoserine DehydrogenaseEC 1.1.1.3Enzyme (Oxidoreductase)BarleyHordeum vulgareGrainModerateAn enzyme in the aspartate family amino acid biosynthesis pathway; studied as an essential contributor to the production of amino acids required for tissue repair.
Omega-3 DesaturaseFAD3; EC 1.14.19.25Enzyme (Oxidoreductase)Chia SeedsSalvia hispanicaSeedModerateIntroduces the omega-3 double bond into linoleic acid; the key enzyme determining ALA content in flaxseed, chia, and other plant omega-3 sources.
Sarcosine OxidaseEC 1.5.3.1Enzyme (Oxidoreductase)Wheat BranTriticum aestivumOuter LayerEmergingStudied for its role in amino acid catabolism and maintaining efficient metabolic clearance of certain nitrogen-containing compounds.
L-Amino Acid OxidaseLAAO; EC 1.4.3.2Enzyme (Oxidoreductase)PeasPisum sativumSeedEmergingStudied for its role in amino acid catabolism and its antimicrobial properties in plant defence systems.
Urate OxidaseUricase; EC 1.7.3.3Enzyme (Oxidoreductase)SoybeanGlycine maxSeedModerateCatalyses the oxidation of uric acid; studied for its potential to support healthy uric acid balance and joint function.
Xanthine OxidaseXO; EC 1.17.3.2Enzyme (Oxidoreductase)Milk ThistleSilybum marianumSeedModerateInvolved in purine catabolism; studied in the context of uric acid management and its relationship to healthy blood chemistry.
Cytochrome c ReductaseEC 1.6.99.3Enzyme (Oxidoreductase)SpinachSpinacia oleraceaLeavesModerateA component of the mitochondrial electron transport chain; essential for efficient cellular energy transfer and ATP production.
LYASE ENZYMES
Phenylalanine Ammonia-LyasePAL; EC 4.3.1.24Enzyme (Lyase)StrawberryFragaria ananassaFruitModerateA key enzyme initiating the phenylpropanoid pathway; triggers the production of plant polyphenols and antioxidants relevant to cardiovascular health.
AldolaseFructose-1,6-bisphosphate aldolase; EC 4.1.2.13Enzyme (Lyase)PeasPisum sativumSeedHighA central glycolytic enzyme that cleaves fructose-1,6-bisphosphate, enabling the efficient conversion of dietary sugars into cellular energy.
Pyruvate DecarboxylasePDC; EC 4.1.1.1Enzyme (Lyase)GrapesVitis viniferaFruitModerateConverts pyruvate to acetaldehyde during anaerobic fermentation; studied in the context of producing fermented plant foods that support gut wellness.
Carbonic AnhydraseCA; EC 4.2.1.1Enzyme (Lyase)KaleBrassica oleraceaLeavesHighCatalyses the reversible hydration of CO2; essential for maintaining the acid-base balance of blood and efficient respiratory gas exchange.
Terpene SynthaseTPS; EC 4.2.3 (class)Enzyme (Lyase)PeppermintMentha piperitaLeavesModerateProduces plant terpenoid compounds including menthol and limonene; the source enzyme for aromatic botanical extracts studied for digestive and respiratory comfort.
AlliinaseAlliin lyase; EC 4.4.1.4Enzyme (Lyase)GarlicAllium sativumBulbHighConverts alliin to allicin when garlic tissue is disrupted; activates the primary heart-health and antimicrobial compounds in garlic.
EnolasePhosphopyruvate hydratase; EC 4.2.1.11Enzyme (Lyase)PotatoSolanum tuberosumTuberHighA key glycolytic enzyme that catalyses the penultimate step of glycolysis, contributing directly to cellular energy production.
FumaraseFumarate hydratase; EC 4.2.1.2Enzyme (Lyase)Citrus FruitsCitrus spp.FruitHighCatalyses the reversible hydration of fumarate to malate in the citric acid cycle; essential for continuous cellular energy production.
Cysteine SynthaseO-acetylserine sulfhydrylase; EC 2.5.1.47Enzyme (Lyase)OnionsAllium cepaBulbModerateSynthesises the amino acid cysteine, which is essential for glutathione production, liver detoxification, and healthy hair and skin.
Ornithine DecarboxylaseODC; EC 4.1.1.17Enzyme (Lyase)TomatoSolanum lycopersicumFruitModerateCatalyses the first step of polyamine biosynthesis; polyamines play a fundamental role in the rapid repair and growth of body tissues.
Arginine DecarboxylaseADC; EC 4.1.1.19Enzyme (Lyase)OatsAvena sativaGrainModerateProduces agmatine and other polyamine precursors; studied for their potential role in supporting the body's resilience to metabolic stress.
Threonine DehydrataseEC 4.3.1.19Enzyme (Lyase)SoybeanGlycine maxSeedModerateConverts threonine to alpha-ketobutyrate for energy; contributes to the efficient use of amino acids during periods of elevated energy demand.
Threonine SynthaseTS; EC 4.2.3.1Enzyme (Lyase)OatsAvena sativaGrainModerateSynthesises the essential amino acid threonine from homoserine phosphate; contributes to the amino acid completeness of oat-based protein.
Cystathionine Beta-LyaseCBL; EC 4.4.1.8Enzyme (Lyase)BroccoliBrassica oleraceaFlower BudsModerateParticipates in the sulfur amino acid metabolism pathway; studied for its contribution to healthy liver sulfur cycle function.
TRANSFERASE ENZYMES
HexokinaseHK; EC 2.7.1.1Enzyme (Transferase)WheatTriticum aestivumGrainHighPhosphorylates glucose as the first committed step of glycolysis; the rate-limiting entry point for dietary glucose into cellular energy metabolism.
Pyruvate KinasePK; EC 2.7.1.40Enzyme (Transferase)PotatoSolanum tuberosumTuberHighCatalyses the final ATP-generating step of glycolysis; essential for the efficient conversion of food into energy to sustain physical activity.
Phosphoglycerate KinasePGK; EC 2.7.2.3Enzyme (Transferase)SpinachSpinacia oleraceaLeavesHighGenerates ATP directly from dietary carbohydrate breakdown; a primary energy-yielding step in glycolysis used by all cells.
Glutathione S-TransferaseGST; EC 2.5.1.18Enzyme (Transferase)CabbageBrassica oleraceaLeavesHighConjugates glutathione to electrophilic compounds; plays a central role in the liver's detoxification of potentially harmful dietary and environmental chemicals.
HexokinaseGlucokinase (Liver); EC 2.7.1.2Enzyme (Transferase)RiceOryza sativaGrainHighActs as a glucose sensor in hepatocytes; helps the body maintain a healthy blood sugar response after carbohydrate-containing meals.
FructokinaseKetohexokinase; EC 2.7.1.4Enzyme (Transferase)TomatoSolanum lycopersicumFruitModeratePhosphorylates dietary fructose specifically in the liver; studied in the context of understanding healthy fructose metabolism and metabolic balance.
PhosphofructokinasePFK; EC 2.7.1.11Enzyme (Transferase)Sweet PotatoIpomoea batatasTuberHighA master regulatory enzyme of glycolysis that controls the rate of glucose breakdown; central to matching energy supply with physical demand.
UDP-Glucose PyrophosphorylaseUGPase; EC 2.7.7.9Enzyme (Transferase)RiceOryza sativaGrainModerateSynthesises UDP-glucose, the activated sugar donor used for glycogen and cellulose biosynthesis, supporting healthy energy storage between meals.
Branching EnzymeStarch Branching Enzyme; EC 2.4.1.18Enzyme (Transferase)PotatoSolanum tuberosumTuberModerateCreates branch points in starch and glycogen molecules; influences the digestibility of starch and the production of resistant starch fractions that feed gut bacteria.
S-Adenosylmethionine SynthetaseSAM Synthetase; EC 2.5.1.6Enzyme (Transferase)GarlicAllium sativumBulbModerateSynthesises SAM, the primary methyl donor in the body; supports liver health, mood-related neurotransmitter synthesis, and the production of sulfur-containing wellness compounds.
GlycosyltransferaseGT; EC 2.4 (class)Enzyme (Transferase)SteviaStevia rebaudianaLeavesModerateA large enzyme family responsible for attaching sugar groups to plant compounds; the enzymes that produce steviol glycosides, the naturally sweet compounds in stevia.
MethyltransferaseMT; EC 2.1.1 (class)Enzyme (Transferase)BeetrootBeta vulgarisRootModerateCatalyses the transfer of methyl groups to a wide range of biological targets; plays a broad role in liver detoxification, DNA methylation, and energy metabolism.
Citrate SynthaseCS; EC 2.3.3.1Enzyme (Transferase)LemonCitrus limonFruitHighCatalyses the entry of acetyl-CoA into the citric acid cycle; the rate-controlling 'spark' that initiates cellular energy production from food.
Alanine AminotransferaseALT; EC 2.6.1.2Enzyme (Transferase)Green Leafy VegVariousLeavesModerateInterconverts alanine and pyruvate; a key enzyme for converting amino acids into energy and maintaining healthy liver metabolic function.
Aspartate AminotransferaseAST; EC 2.6.1.1Enzyme (Transferase)Root VegetablesVariousRootsModerateLinks amino acid and carbohydrate metabolism; essential for ensuring continuous energy availability in heart and liver cells.
Branched-Chain AminotransferaseBCAT; EC 2.6.1.42Enzyme (Transferase)Garden PeasPisum sativumSeedModerateCatalyses the first step in the catabolism of branched-chain amino acids (leucine, isoleucine, valine); studied for its role in muscle protein synthesis and recovery.
Glycine HydroxymethyltransferaseSHMT; EC 2.1.2.1Enzyme (Transferase)RiceOryza sativaGrainModerateInterconverts glycine and serine while transferring one-carbon units; essential for folate metabolism and healthy DNA synthesis.
Serine HydroxymethyltransferaseSHMT; EC 2.1.2.1Enzyme (Transferase)SpinachSpinacia oleraceaLeavesModerateA central enzyme linking amino acid metabolism to folate-dependent one-carbon metabolism; essential for healthy cell replication.
Methionine SynthaseMS; EC 2.1.1.13Enzyme (Transferase)LentilsLens culinarisSeedModerateRegenerates methionine from homocysteine using folate and B12; studied for its role in maintaining healthy homocysteine levels as a cardiovascular marker.
Spermidine SynthaseSpdS; EC 2.5.1.16Enzyme (Transferase)Wheat GermTriticum aestivumGermModerateSynthesises spermidine, a polyamine associated with cellular autophagy and longevity signalling; studied in the context of healthy aging.
Betaine-Homocysteine MethyltransferaseBHMT; EC 2.1.1.5Enzyme (Transferase)BeetrootBeta vulgarisRootModerateConverts homocysteine to methionine using betaine; may support healthy cardiovascular function by contributing to normal homocysteine balance.
Phytoene SynthasePSY; EC 2.5.1.32Enzyme (Transferase)CarrotDaucus carotaRootModerateCatalyses the first committed step of carotenoid biosynthesis; the enzyme that initiates the production of beta-carotene and the provitamin A found in colourful plants.
Lycopene Beta-CyclaseLYCB; EC 5.5.1.19Enzyme (Isomerase)PumpkinCucurbita maximaFruitModerateConverts the linear carotenoid lycopene into cyclic beta-carotene; the enzyme responsible for producing Vitamin A precursors from plant pigments.
ThiolaseAcetyl-CoA acetyltransferase; EC 2.3.1.9Enzyme (Transferase)Sunflower SeedsHelianthus annuusSeedModerateCatalyses the thiolytic cleavage of acetoacetyl-CoA; plays a key role in fatty acid beta-oxidation and healthy fat-derived energy production.
Beta-Ketoacyl-ACP SynthaseKAS; EC 2.3.1.41Enzyme (Transferase)CoconutCocos nuciferaEndospermModerateA key enzyme in de novo fatty acid synthesis; determines the chain length and type of fatty acids produced in plant seeds.
Glycerol-3-Phosphate AcyltransferaseGPAT; EC 2.3.1.15Enzyme (Transferase)AvocadoPersea americanaFruitModerateCatalyses the first step in glycerolipid biosynthesis; essential for building the structural phospholipids that comprise every human cell membrane.
Malate SynthaseMS; EC 2.3.3.9Enzyme (Transferase)Sunflower SeedsHelianthus annuusSeedModerateA glyoxylate cycle enzyme that converts acetyl-CoA and glyoxylate to malate; studied for its role in the efficient conversion of stored fats to cellular energy.
Creatine KinaseCK; EC 2.7.3.2Enzyme (Transferase)Whole GrainsVariousGrainModerateCatalyses the transfer of a phosphate group to ADP to regenerate ATP; plays a central role in the rapid energy demands of muscle and nerve tissues.
Adenylate KinaseAK; EC 2.7.4.3Enzyme (Transferase)SpinachSpinacia oleraceaLeavesModerateMaintains the cellular energy charge by interconverting ATP, ADP, and AMP; acts as a sensitive sensor and regulator of cellular energy status.
Nucleoside-Diphosphate KinaseNDPK; EC 2.7.4.6Enzyme (Transferase)KaleBrassica oleraceaLeavesModerateSynthesises nucleoside triphosphates from ATP; provides the activated nucleotide building blocks required for DNA and RNA repair and synthesis.
RNA PolymeraseRNAP; EC 2.7.7.6Enzyme (Transferase)Rice GermOryza sativaGermHighTranscribes DNA into RNA; the fundamental enzyme required for the expression of all genetic information and the production of proteins.
Ornithine CarbamoyltransferaseOTC; EC 2.1.3.3Enzyme (Transferase)PeanutsArachis hypogaeaSeedModerateA central enzyme of the urea cycle that helps the liver safely convert protein-derived ammonia into urea for excretion.
PhosphoglucoisomerasePGI; EC 5.3.1.9Enzyme (Isomerase)CornZea maysGrainHighInterconverts glucose-6-phosphate and fructose-6-phosphate; an essential step in glycolysis for converting dietary glucose into usable cellular fuel.
ISOMERASE ENZYMES
Glucose IsomeraseXylose isomerase; EC 5.3.1.5Enzyme (Isomerase)BarleyHordeum vulgareGrainModerateInterconverts glucose and fructose; widely used in the food industry and studied for its role in balanced dietary sugar management.
Triose Phosphate IsomeraseTPI; EC 5.3.1.1Enzyme (Isomerase)SpinachSpinacia oleraceaLeavesHighInterconverts the two triose phosphate intermediates of glycolysis; essential for the efficient extraction of energy from every glucose molecule.
EpimeraseUDP-glucose 4-epimerase; EC 5.1.3.2Enzyme (Isomerase)SoybeanGlycine maxSeedModerateInterconverts UDP-glucose and UDP-galactose; essential for the body's biosynthesis of glycoproteins and cell membrane glycolipids.
RacemaseAlanine racemase; EC 5.1.1.1Enzyme (Isomerase)AlfalfaMedicago sativaLeavesModerateInterconverts L- and D-amino acids; studied for its role in the proper formation of structural proteins and supporting a healthy gut microbiome.
LIGASE ENZYMES
DNA LigaseEC 6.5.1.1Enzyme (Ligase)Broccoli SproutsBrassica oleraceaWhole SproutHighCatalyses the joining of DNA strand breaks; an essential enzyme for the faithful repair and replication of the human genome.
Glutamine SynthetaseGS; EC 6.3.1.2Enzyme (Ligase)PeanutsArachis hypogaeaSeedHighSynthesises glutamine from glutamate and ammonia; glutamine is the primary fuel for immune cells and a key molecule for maintaining gut lining integrity.
Acetyl-CoA CarboxylaseACC; EC 6.4.1.2Enzyme (Ligase)SunflowerHelianthus annuusSeedModerateCatalyses the rate-limiting step in de novo fatty acid synthesis; determines the body's capacity to produce healthy structural and regulatory fats.
Pyruvate CarboxylasePC; EC 6.4.1.1Enzyme (Ligase)SoybeanGlycine maxSeedModerateConverts pyruvate to oxaloacetate, replenishing the citric acid cycle; essential for maintaining the steady supply of energy in heart and brain tissues.
S-Adenosylmethionine SynthetaseMAT; EC 2.5.1.6Enzyme (Ligase)GarlicAllium sativumBulbModerateSynthesises SAM from methionine and ATP; SAM is the universal methyl donor supporting mood-related neurotransmitter synthesis and liver function.
Leucyl-tRNA SynthetaseLeuRS; EC 6.1.1.4Enzyme (Ligase)Pumpkin SeedsCucurbita pepoSeedModerateAminoacylates leucine onto its cognate tRNA; plays a role in nutrient sensing and has been studied as an activator of the mTOR pathway regulating muscle protein synthesis.
Tryptophanyl-tRNA SynthetaseTrpRS; EC 6.1.1.2Enzyme (Ligase)Chia SeedsSalvia hispanicaSeedModerateEnsures tryptophan is correctly incorporated during protein synthesis; studied for its connection to the production of serotonin and sleep-supporting melatonin.
Lysine-tRNA LigaseLysRS; EC 6.1.1.6Enzyme (Ligase)QuinoaChenopodium quinoaSeedModerateEnsures the accurate incorporation of lysine into proteins; lysine is an essential amino acid critical for collagen synthesis and tissue repair.
Tyrosine-tRNA LigaseTyrRS; EC 6.1.1.1Enzyme (Ligase)Pumpkin SeedsCucurbita pepoSeedModerateEnsures tyrosine is correctly incorporated during protein synthesis; studied for its links to neurotransmitter and thyroid hormone production.
Valine-tRNA LigaseValRS; EC 6.1.1.9Enzyme (Ligase)LentilsLens culinarisSeedModerateRequired for the correct incorporation of valine into proteins; valine is a branched-chain amino acid important for muscle repair and recovery.
Histidine-tRNA LigaseHisRS; EC 6.1.1.21Enzyme (Ligase)PeanutsArachis hypogaeaSeedModerateEnsures histidine is correctly incorporated during protein synthesis; studied for its connection to the production of histamine and the body's inflammatory response.
Carbamoyl Phosphate SynthetaseCPS; EC 6.3.4.16Enzyme (Ligase)Sunflower SeedsHelianthus annuusSeedModerateInitiates the urea cycle by synthesising carbamoyl phosphate; essential for the liver's safe disposal of excess dietary protein nitrogen.
MULTI-FUNCTIONAL / COMPLEX PROTEINS
RuBisCoRibulose-1,5-bisphosphate carboxylase/oxygenase; EC 4.1.1.39Protein / EnzymeSpinachSpinacia oleraceaLeavesModerateThe most abundant protein on Earth; provides a nutritionally complete amino acid profile when consumed as a leaf protein concentrate, with emerging interest as a sustainable plant protein source.
RibonucleaseRNase; EC 3.1.26.4Enzyme (Hydrolase)SpinachSpinacia oleraceaLeavesModerateCatalyses the degradation of RNA; involved in cellular RNA turnover and the recycling of nucleotide building blocks.
DeoxyribonucleaseDNase; EC 3.1.21.1Enzyme (Hydrolase)TomatoSolanum lycopersicumFruitModerateCatalyses the hydrolysis of DNA; plays a housekeeping role in the safe recycling of genetic material within tissues.
GlutaminaseGLS; EC 3.5.1.2Enzyme (Hydrolase)MisoGlycine maxFermented BeanModerateConverts glutamine to glutamate; releases flavour-active amino acids in fermented plant foods and produces glutamate as fuel for rapidly dividing immune and gut cells.
Alpha-MannosidaseEC 3.2.1.24Enzyme (Hydrolase)Jack BeanCanavalia ensiformisSeedModerateRemoves mannose residues from glycoproteins during their maturation; essential for the correct folding and quality control of secreted proteins.
Beta-MannosidaseEC 3.2.1.25Enzyme (Hydrolase)Guar BeanCyamopsis tetragonolobaSeedModerateHydrolyses terminal mannose residues from galactomannans; studied for its contribution to fiber digestion and healthy blood cholesterol management.
Leucine AminopeptidaseLAP; EC 3.4.11.1Enzyme (Hydrolase)BarleyHordeum vulgareGrainModerateCleaves N-terminal amino acids from peptide chains; supports the final stages of protein digestion for maximum nutrient absorption.
CarboxypeptidaseEC 3.4.17 (class)Enzyme (Hydrolase)SoybeanGlycine maxSeedModerateRemoves amino acids from the C-terminus of peptides; assists in the complete breakdown of dietary protein into absorbable amino acids.
AminopeptidaseEC 3.4.11 (class)Enzyme (Hydrolase)Cereal GrainsVariousGermModerateCleaves single amino acids from the N-terminus of peptide chains, completing the digestion of dietary proteins for direct absorption.
Adenosine DeaminaseADA; EC 3.5.4.4Enzyme (Hydrolase)PotatoSolanum tuberosumTuberModerateCatalyses the deamination of adenosine in the purine salvage pathway; a critical enzyme for normal T-cell immune function and healthy cellular communication.
GlucokinaseHexokinase IV; EC 2.7.1.2Enzyme (Transferase)RiceOryza sativaGrainModerateFunctions as a hepatic glucose sensor that helps regulate insulin secretion; studied for its central role in maintaining healthy post-meal blood sugar balance.
VITAMIN C
Vitamin CAscorbic acid; L-Ascorbic acid; E300Vitamins (Vitamin C)Rose HipsRosa caninaFruit50-81-7HighA well-validated water-soluble antioxidant essential for normal immune function, collagen synthesis, and iron absorption from plant foods.
PROVITAMIN A CAROTENOIDS
Beta-caroteneProvitamin A; beta,beta-CaroteneVitamins (Provitamin A Carotenoid)CarrotDaucus carotaRoot7235-40-7HighA provitamin A carotenoid converted by the body to retinol as needed; supports healthy vision, normal immune function, and skin integrity.
Alpha-carotenealpha,beta-CaroteneVitamins (Provitamin A Carotenoid)PumpkinCucurbita maximaFruit7488-99-5ModerateA provitamin A carotenoid with roughly half the conversion efficiency of beta-carotene; may contribute to healthy cell growth and immune defence.
Beta-cryptoxanthinbeta-Cryptoxanthin; CryptoxanthinVitamins (Provitamin A Carotenoid)PapayaCarica papayaFruit472-70-8ModerateA xanthophyll provitamin A that may be specifically supportive of lung and respiratory cell health, in addition to general vitamin A functions.
CAROTENOIDS — NON-PROVITAMIN A
LuteinXanthophyll; E161bVitamins (Carotenoid)KaleBrassica oleraceaLeaves127-40-2HighAccumulates in the macular pigment of the eye; well-supported for reducing the risk of age-related macular degeneration and protecting against blue light stress.
Zeaxanthin(3R,3'R)-Zeaxanthin; E161hVitamins (Carotenoid)Sweet CornZea maysGrains144-68-3HighA macular pigment carotenoid that may improve visual sharpness and help protect the retina from UV-induced oxidative damage.
LycopenePsi,psi-Carotene; E160dVitamins (Carotenoid)TomatoSolanum lycopersicumFruit502-65-8HighA well-studied antioxidant carotenoid associated with cardiovascular health and potential skin photoprotection when consumed regularly as part of a varied diet.
Phytoene7,8,11,12,7',8'-Hexahydro-lycopeneVitamins (Carotenoid)White TomatoSolanum lycopersicumFruit542-42-7ModerateA colourless carotenoid that may absorb UV light at the cellular level and contribute to overall skin antioxidant status.
PhytofluenePhytofluene; 7,8-Dihydro-zeta-caroteneVitamins (Carotenoid)TomatoSolanum lycopersicumFruit554-84-7EmergingA colourless carotenoid studied in early-stage research for its potential role in complementing the photoprotective and antioxidant effects of other carotenoids.
Astaxanthin(3S,3'S)-Astaxanthin; Haematococcus ExtractVitamins (Carotenoid)AlgaeHaematococcus pluvialisWhole Cell472-61-7HighA ketocarotenoid with exceptionally potent antioxidant activity; may support eye health, skin photoprotection, and exercise recovery when consumed regularly.
Fucoxanthin(3S,5R,6S,3'S,5'R)-FucoxanthinVitamins (Carotenoid)KelpUndaria pinnatifidaWhole Plant3351-86-8ModerateA marine carotenoid found in edible seaweeds; may support healthy metabolic rate and contribute to weight management when consumed as part of a balanced diet.
Capsanthin(3R,3'S,5'R)-CapsanthinVitamins (Carotenoid)Red PepperCapsicum annuumFruit465-42-9ModerateA xanthophyll carotenoid unique to Capsicum; studied for its potential to contribute to a healthy lipid profile and support eye function.
Neoxanthin(3S,5R,6R,3'S,5'R,6'S)-NeoxanthinVitamins (Carotenoid)SpinachSpinacia oleraceaLeaves14646-79-8ModerateA minor dietary xanthophyll studied for its potential antioxidant and metabolic balance-supporting properties.
ViolaxanthinZeaxanthin diepoxideVitamins (Carotenoid)Yellow PepperCapsicum annuumFruit126-29-4ModerateA plant xanthophyll studied for its antioxidant potential and contribution to the diverse carotenoid intake from colourful vegetables.
VITAMIN E — TOCOPHEROLS
Alpha-tocopherolRRR-alpha-Tocopherol; Vitamin E; E307Vitamins (Vitamin E / Tocopherol)Wheat GermTriticum aestivumGerm59-02-9HighThe most biologically active form of Vitamin E; protects cell membranes from oxidative damage and supports normal immune function.
Gamma-tocopherolgamma-TocopherolVitamins (Vitamin E / Tocopherol)WalnutJuglans regiaNut Kernel54-28-4ModerateMay provide complementary anti-inflammatory protection to alpha-tocopherol; studied for its ability to neutralise reactive nitrogen species in tissues.
Delta-tocopheroldelta-TocopherolVitamins (Vitamin E / Tocopherol)Soybean OilGlycine maxSeed Oil119-13-1ModerateA potent antioxidant tocopherol isomer studied for its potential contribution to maintaining the stability of cell membrane lipids.
Beta-tocopherolbeta-TocopherolVitamins (Vitamin E / Tocopherol)Various GrainsN/ASeed16698-35-4ModerateA minor tocopherol isomer that may contribute to the overall protective antioxidant activity of mixed Vitamin E complexes.
VITAMIN E — TOCOTRIENOLS
Alpha-tocotrienolalpha-T3Vitamins (Vitamin E / Tocotrienol)Palm FruitElaeis guineensisFruit58864-81-6ModerateA tocotrienol form of Vitamin E with greater membrane mobility than tocopherols; studied for its potential neuroprotective and cardioprotective properties.
Gamma-tocotrienolgamma-T3Vitamins (Vitamin E / Tocotrienol)Rice BranOryza sativaBran14101-61-2ModerateStudied for its potential to support healthy cholesterol levels and provide antioxidant protection to cardiovascular tissues.
Delta-tocotrienoldelta-T3Vitamins (Vitamin E / Tocotrienol)Annatto SeedsBixa orellanaSeed25612-59-3ModerateThe predominant tocotrienol in annatto; studied for its potential contributions to long-term heart health and cellular antioxidant protection.
VITAMIN K
Vitamin K1Phylloquinone; Phytonadione; K1Vitamins (Vitamin K)SpinachSpinacia oleraceaLeaves84-80-0HighThe primary dietary form of Vitamin K from plants; essential for normal blood coagulation and for directing calcium to bones rather than soft tissues.
VITAMIN D
Vitamin D2Ergocalciferol; Calciferol; E1141Vitamins (Vitamin D)UV-Exposed MushroomAgaricus bisporusFruiting Body50-14-6HighA plant-derived form of Vitamin D produced when mushrooms are exposed to UV light; may support bone mineralisation and healthy immune function, though D3 conversion efficiency is lower than solar D3.
B VITAMINS
Vitamin B1Thiamine; AneurineVitamins (Vitamin B)Sunflower SeedsHelianthus annuusSeed59-43-8HighEssential for converting dietary carbohydrates into cellular energy; supports normal nerve function and healthy heart muscle activity.
Vitamin B2Riboflavin; Lactoflavin; E101Vitamins (Vitamin B)AlmondsPrunus dulcisNut Kernel83-88-5HighRequired for energy production from fats, proteins, and carbohydrates; supports healthy skin integrity and normal eye function.
Vitamin B3Niacin; Nicotinic acid; NicotinamideVitamins (Vitamin B)PeanutsArachis hypogaeaSeed59-67-6HighA precursor to NAD and NADP coenzymes central to energy metabolism; supports healthy DNA repair, normal skin function, and healthy circulation.
Vitamin B5Pantothenic acid; PantothenateVitamins (Vitamin B)AvocadoPersea americanaFruit79-83-4HighRequired for the synthesis of coenzyme A; supports the body's normal response to stress and healthy energy metabolism from all macronutrients.
Vitamin B6Pyridoxine; Pyridoxal; PyridoxamineVitamins (Vitamin B)ChickpeasCicer arietinumSeed65-23-6HighEssential for over 100 enzyme reactions including amino acid metabolism and neurotransmitter synthesis; supports normal mood regulation, cognitive function, and haemoglobin production.
Vitamin B7Biotin; Vitamin HVitamins (Vitamin B)SoybeansGlycine maxSeed58-85-5HighA coenzyme for carboxylase enzymes involved in fatty acid synthesis and gluconeogenesis; supports normal macronutrient metabolism, and healthy hair and nail growth.
Vitamin B9Folate; Folic acid; Pteroylglutamic acidVitamins (Vitamin B)LentilsLens culinarisSeed59-30-3HighEssential for one-carbon metabolism, normal DNA synthesis, and healthy cell division; critical during early pregnancy for normal foetal neural tube development.
Vitamin B12 (Corrinoid Analog)Pseudovitamin B12; Cobalamin analogVitamins (Vitamin B)NoriPorphyra spp.FrondsEmergingThe B12-like corrinoid compounds found in nori have contested bioactivity; current evidence suggests they may not function as true cobalamin and could potentially compete with active B12 for absorption. Not considered a reliable B12 source for those on plant-based diets.
ESTABLISHED VITAMIN-LIKE FACTORS
PQQPyrroloquinoline quinone; Methoxatin; BioPQQVitamin-like FactorGreen PepperCapsicum annuumFruit72909-34-3ModerateA redox-active cofactor studied for its potential to support mitochondrial biogenesis and contribute to mental clarity and focus when consumed as part of a healthy diet.
Choline(2-Hydroxyethyl)trimethylammonium; BilineurineVitamin-like FactorWheat GermTriticum aestivumGerm62-49-7HighAn essential nutrient required for the synthesis of phosphatidylcholine and acetylcholine; critical for normal liver function, healthy brain development, and cognitive performance.
BetaineTrimethylglycine; TMG; Glycine betaineVitamin-like FactorSugar BeetBeta vulgarisRoot107-43-7HighAn osmolyte and methyl donor that may support healthy liver function and contribute to normal homocysteine balance, a key cardiovascular health marker.
Quinic Acid1L-1(OH),3,4/5-Tetrahydroxycyclohexane-carboxylic acidVitamin-like FactorCranberryVaccinium macrocarponFruit77-95-2ModerateA plant acid that may support urinary tract health by contributing to hippuric acid production; also plays a role in the biosynthesis of aromatic amino acids in plants.
SolanesolAll-trans-Solanesol; C45 isoprenyl alcoholVitamin-like FactorPotato LeavesSolanum tuberosumLeaves13190-97-1ModerateA long-chain isoprenyl alcohol found in Solanaceae plants; studied as a biosynthetic precursor to coenzyme Q10 (CoQ10) and Vitamins E and K in certain organisms.
ANTHOCYANINS (NOTE: SECONDARY METABOLITES — TO BE MIGRATED TO SECONDARY TABLE)
Anthocyanin — CyanidinCyanidin; Cyanidin chloridePhytochemical (Anthocyanin)BlackberryRubus fruticosusFruit528-58-5ModerateA red-blue anthocyanin pigment studied for its potential to support vascular health and contribute to normal circulation when consumed as part of a fruit-rich diet.
Anthocyanin — DelphinidinDelphinidinPhytochemical (Anthocyanin)BlueberryVaccinium corymbosumFruit528-53-0ModerateA blue-purple anthocyanin studied for its potential contribution to healthy cognitive aging and protection of the eyes from oxidative fatigue.
Anthocyanin — PelargonidinPelargonidinPhytochemical (Anthocyanin)StrawberryFragaria ananassaFruit134-04-3ModerateAn orange-red anthocyanin pigment studied for its potential anti-inflammatory effects with possible relevance to joint and skin health.
Anthocyanin — PeonidinPeonidinPhytochemical (Anthocyanin)Purple Sweet PotatoIpomoea batatasTuber134-01-0ModerateA red anthocyanin studied for its potential to support the body's antioxidant defence and contribute to a healthy inflammatory response.
Anthocyanin — MalvidinMalvidinPhytochemical (Anthocyanin)Red GrapesVitis viniferaFruit Peel643-84-5ModerateA blue-red anthocyanin studied for its potential contribution to heart health by supporting normal arterial function and reducing oxidative stress.
FLAVONOLS & FLAVONES (NOTE: SECONDARY METABOLITES — TO BE MIGRATED TO SECONDARY TABLE)
Quercetin3,3',4',5,7-Pentahydroxyflavone; SophoretinPhytochemical (Flavonol)Red OnionAllium cepaBulb117-39-5ModerateA widely studied dietary flavonol studied for its potential to support normal immune function and contribute to antioxidant defence; some evidence for synergy with Vitamin C.
RutinQuercetin-3-rutinoside; Rutoside; E303Phytochemical (Flavonol)BuckwheatFagopyrum esculentumLeaves153-18-4ModerateThe glycosylated form of quercetin; studied for its potential to support the structural integrity of capillaries and contribute to healthy circulation.
Kaempferol3,5,7,4'-TetrahydroxyflavonePhytochemical (Flavonol)BroccoliBrassica oleraceaFlorets520-18-3ModerateA plant flavonol studied for its potential anti-inflammatory and antioxidant properties; may contribute to cardiovascular protection when consumed regularly in plant-rich diets.
Apigenin4',5,7-Trihydroxyflavone; Chamomile FlavonePhytochemical (Flavone)ParsleyPetroselinum crispumLeaves520-36-5ModerateA flavone studied for its potential to support healthy nervous system function and contribute to a calm physiological state; moderate evidence from in vitro and animal models.
HesperidinHesperetin-7-rutinoside; Vitamin P componentPhytochemical (Flavanone Glycoside)OrangeCitrus sinensisFruit Peel520-26-3ModerateA citrus flavanone glycoside studied for its potential to support normal inflammatory balance and contribute to cardiovascular health.
Naringenin4',5,7-Trihydroxyflavanone; Citrus FlavanonePhytochemical (Flavanone)GrapefruitCitrus paradisiFruit480-41-1ModerateA citrus flavanone studied for its potential to improve insulin sensitivity and contribute to healthy weight and metabolic balance.
Eriodictyol3',4',5,7-TetrahydroxyflavanonePhytochemical (Flavanone)LemonCitrus limonFruit552-58-9ModerateA citrus flavanone studied for its potential antioxidant and mild anti-inflammatory properties, with emerging interest in respiratory health applications.
ISOFLAVONES (NOTE: SECONDARY METABOLITES — TO BE MIGRATED TO SECONDARY TABLE)
Genistein5,7,4'-Trihydroxyisoflavone; Soy IsoflavonePhytochemical (Isoflavone)SoybeanGlycine maxSeed446-72-0ModerateA phytoestrogenic isoflavone studied for its potential to support hormonal balance and bone density, particularly relevant to menopausal health. Evidence is mixed and context-dependent.
Daidzein7,4'-Dihydroxyisoflavone; Soy IsoflavonePhytochemical (Isoflavone)SoybeanGlycine maxSeed486-66-8ModerateA phytoestrogenic isoflavone studied for its potential cardiovascular and antioxidant properties; bioactivity varies significantly between individuals based on gut microbiome composition.
STILBENES (NOTE: SECONDARY METABOLITES — TO BE MIGRATED TO SECONDARY TABLE)
ResveratrolTrans-resveratrol; 3,5,4'-TrihydroxystilbenePhytochemical (Stilbene)Red GrapesVitis viniferaFruit Skin501-36-0ModerateA polyphenolic stilbene studied for potential activation of sirtuin longevity pathways and cardiovascular protection; human bioavailability is limited and evidence is still emerging.
FLAVAN-3-OLS (NOTE: SECONDARY METABOLITES — TO BE MIGRATED TO SECONDARY TABLE)
Catechin(+)-Catechin; Catechinic acidPhytochemical (Flavan-3-ol)Green TeaCamellia sinensisLeaves154-23-4ModerateA flavan-3-ol studied for its potential to contribute to metabolic health and antioxidant protection of brain cells when consumed regularly as green tea.
Epicatechin(-)-Epicatechin; ECPhytochemical (Flavan-3-ol)CocoaTheobroma cacaoBean490-46-0ModerateA flavan-3-ol studied for its potential to support healthy blood flow and vascular function; may contribute to normal muscle function and recovery.
EGCGEpigallocatechin gallate; EGCg; Tea CatechinPhytochemical (Flavan-3-ol)Green TeaCamellia sinensisLeaves989-51-5ModerateThe most abundant and studied catechin in green tea; studied for its potential to support metabolic health, immune function, and antioxidant defence. Evidence from human trials is moderate.
OTHER BIOACTIVE PHYTOCHEMICALS (NOTE: SECONDARY METABOLITES — TO BE MIGRATED TO SECONDARY TABLE)
CurcuminDiferuloylmethane; Turmeric Yellow; E100Phytochemical (Diarylheptanoid)TurmericCurcuma longaRhizome458-37-7ModerateA polyphenolic diarylheptanoid studied for its potential to support normal inflammatory balance; poor oral bioavailability limits effects without formulation enhancement such as piperine or lipid delivery.
Sulforaphane1-Isothiocyanato-4-(methylsulfinyl)butane; SFPhytochemical (Isothiocyanate)BroccoliBrassica oleraceaSprouts4478-93-7ModerateAn isothiocyanate produced from glucoraphanin by myrosinase; studied for its potential to activate Nrf2 detoxification pathways. Requires fresh or lightly cooked broccoli for maximum yield.
AllicinDiallyl thiosulfinate; AllicinPhytochemical (Organosulfur)GarlicAllium sativumBulb539-86-6ModerateAn organosulfur compound formed from alliin by alliinase when garlic is crushed; studied for its potential antimicrobial and cardiovascular-supportive properties. Unstable — activity diminishes rapidly with cooking.
Capsaicin8-Methyl-N-vanillyl-6-nonenamide; CapsaicinPhytochemical (Capsaicinoid)Chili PepperCapsicum frutescensFruit404-86-4ModerateA vanilloid compound that binds TRPV1 receptors; studied for its potential to support energy expenditure and as a topical analgesic agent for localised pain management.
MACROMINERALS
CalciumCa; Calcium ion; E170Minerals (Macromineral)Collard GreensBrassica oleraceaLeaves7440-70-2HighThe most abundant mineral in the human body; essential for structural bone and tooth health, normal muscle contraction, and healthy nerve signal transmission.
MagnesiumMg; Magnesium ionMinerals (Macromineral)Pumpkin SeedsCucurbita pepoSeed7439-95-4HighA cofactor for over 300 enzymatic reactions; supports normal muscle and nerve function, healthy blood glucose regulation, and bone mineralisation.
PotassiumK; Potassium ionMinerals (Macromineral)BananaMusa acuminataFruit7440-09-7HighThe primary intracellular cation; essential for maintaining normal fluid balance, healthy blood pressure, and proper electrical activity in muscle and nerve cells.
PhosphorusP; Phosphate ionMinerals (Macromineral)OatsAvena sativaGrains7723-14-0HighRequired by every cell for energy metabolism (ATP), DNA and RNA synthesis, and structural bone and tooth mineralisation in conjunction with calcium.
SulfurS; Organic sulfurMinerals (Macromineral)GarlicAllium sativumBulb7704-34-9HighAn essential component of the amino acids methionine and cysteine; required for the synthesis of glutathione, the body's primary endogenous antioxidant.
SodiumNa; Sodium ionMinerals (Macromineral)CeleryApium graveolensStalk7440-23-5HighThe primary extracellular cation; essential for maintaining normal fluid balance, blood pressure regulation, and healthy nerve and muscle electrical function.
ChlorideCl-; Chloride ionMinerals (Macromineral)TomatoSolanum lycopersicumFruit16887-00-6HighThe primary extracellular anion; essential for maintaining acid-base balance and a component of hydrochloric acid required for normal gastric digestion.
TRACE MINERALS
IronFe; Non-heme iron; Ferrous ironMinerals (Trace Mineral)SpinachSpinacia oleraceaLeaves7439-89-6HighA core component of haemoglobin and myoglobin; essential for normal oxygen transport throughout the body and healthy energy metabolism. Plant-source non-heme iron absorption is enhanced by Vitamin C.
ZincZn; Zinc ionMinerals (Trace Mineral)Pumpkin SeedsCucurbita pepoSeed7440-66-6HighA cofactor for over 300 enzymes; supports normal immune function, healthy wound healing, DNA synthesis, and the senses of taste and smell.
CopperCu; Cupric ionMinerals (Trace Mineral)CashewsAnacardium occidentaleNut Kernel7440-50-8HighA cofactor for enzymes involved in iron metabolism, antioxidant defence (SOD), and connective tissue formation; supports healthy energy production and cardiovascular function.
ManganeseMn; Manganese ionMinerals (Trace Mineral)HazelnutsCorylus avellanaNut Kernel7439-96-5HighA cofactor for manganese superoxide dismutase and enzymes involved in bone formation; supports normal carbohydrate and fat metabolism.
SeleniumSe; Selenium ionMinerals (Trace Mineral)Brazil NutBertholletia excelsaNut Kernel7782-49-2HighAn essential component of glutathione peroxidase and other selenoproteins; supports normal thyroid hormone metabolism and antioxidant protection of cells.
ChromiumCr; Trivalent chromium; Cr3+Minerals (Trace Mineral)BroccoliBrassica oleraceaFlorets7440-47-3ModerateMay enhance the action of insulin in supporting normal blood glucose uptake; studied for its role in healthy carbohydrate and lipid metabolism.
IodineI; Iodide ionMinerals (Trace Mineral)KelpMacrocystis pyriferaWhole Plant7553-56-2HighAn essential component of the thyroid hormones T3 and T4; required for normal metabolic rate, healthy growth, and neurological development.
MolybdenumMo; Molybdenum ionMinerals (Trace Mineral)LentilsLens culinarisSeed7439-98-7HighA cofactor for several enzymes including xanthine oxidase and sulfite oxidase; essential for normal purine catabolism and sulfur amino acid metabolism.
SiliconSi; Soluble silica; Orthosilicic acidMinerals (Trace Mineral)HorsetailEquisetum arvenseStems7440-21-3ModerateStudied for its potential role in supporting collagen synthesis and normal bone and connective tissue formation; may contribute to healthy hair and nail strength.
BoronB; BorateMinerals (Trace Mineral)AvocadoPersea americanaFruit7440-42-8ModerateStudied for its potential to support normal bone metabolism by influencing the utilisation of calcium, magnesium, and Vitamin D; may contribute to healthy hormonal balance.
VanadiumV; Vanadyl ion; VOSO4Minerals (Trace Mineral)DillAnethum graveolensLeaves7440-62-2EmergingA trace element studied in early-stage research for its potential to mimic insulin signalling and support healthy bone mineral density; human evidence remains limited.
NickelNi; Nickel ionMinerals (Trace Mineral)BuckwheatFagopyrum esculentumSeed7440-02-0EmergingA trace element found in some urease and hydrogenase enzymes; studied for its minor role in gut microbiome metabolism. High dietary intake may cause sensitivity in some individuals.
LithiumLi; Lithium ionMinerals (Trace Mineral)CabbageBrassica oleraceaLeaves7439-93-2EmergingPresent in trace amounts in many plant foods; studied for its potential role in neuroprotection and emotional resilience at physiological dietary levels. Pharmacological doses are used clinically under medical supervision.
GermaniumGe; Organic germaniumMinerals (Trace Mineral)GinsengPanax ginsengRoot7440-56-4EmergingAn ultra-trace element found in some medicinal plants; studied in early-stage research for potential immunomodulatory properties. Evidence in humans is very limited.
StrontiumSr; Strontium ionMinerals (Trace Mineral)Wheat BranTriticum aestivumOuter Layer7440-24-6ModerateA trace element chemically similar to calcium; studied for its potential to support bone mineral density and skeletal tissue repair at physiological intake levels.
CobaltCo; Cobalt ionMinerals (Trace Mineral)PeasPisum sativumSeed7440-48-4HighAn essential component of Vitamin B12 (cobalamin); dietary cobalt supports the enzymatic functions of B12 in red blood cell formation and neurological health.
FluorideF-; Fluoride ionMinerals (Trace Mineral)Green TeaCamellia sinensisLeaves16984-48-8HighNaturally present in plant foods and drinking water; supports the remineralisation of tooth enamel and may help prevent dental caries at appropriate intake levels.
RubidiumRb; Rubidium ionMinerals (Trace Mineral)Coffee BeanCoffea arabicaBean7440-17-7EmergingAn ultra-trace element that may interact with potassium transport systems; studied in early-stage research for potential contributions to healthy cardiovascular electrical function.
CesiumCs; Caesium ionMinerals (Trace Mineral)SpinachSpinacia oleraceaLeaves7440-46-2EmergingAn ultra-trace element present in very small quantities in plant foods; studied for its interaction with potassium channels at physiological trace levels. Not to be confused with pharmacological cesium applications.
MINERAL FACTORS
FerritinPlant Ferritin; PhytoferritinMineral Factor (Iron Storage Protein)SoybeanGlycine maxSeed9007-73-2ModerateThe iron-storage protein found in plant seeds; studied as a potentially more stomach-friendly form of plant-derived iron with moderate bioavailability.
Inositol HexaphosphateIP6; Phytic acid; InsP6; E391Mineral Factor (Phosphate Ester)Rice BranOryza sativaBran83-86-3ModerateA naturally occurring phosphorylated inositol studied for its potential antioxidant properties and ability to chelate iron in the gut; context-dependent effects on mineral absorption and cellular signalling.

← Swipe table to see all columns →

// SECONDARY METABOLITES: BIOACTIVE SIGNALS
Compound Also Known As Class (Sub-class) Plant Source Botanical Name Plant Part CAS No. Claim Strength Primary Biological Action
ISOQUINOLINE ALKALOIDS
MorphineMorphia; MS Contin; OpioidAlkaloid (Isoquinoline)Opium PoppyPapaver somniferumUnripe Capsule Latex57-27-2HighA clinically established opioid analgesic used under medical supervision for severe pain management; associated with significant dependence and respiratory depression risk.
Codeine3-Methylmorphine; Codeine phosphateAlkaloid (Isoquinoline)Opium PoppyPapaver somniferumUnripe Capsule Latex76-57-3HighA mild opioid used clinically for moderate pain relief and cough suppression; subject to controlled substance regulations in most jurisdictions.
Berberine5,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinoliziniumAlkaloid (Isoquinoline)Goldenseal / BarberryHydrastis canadensis / Berberis spp.Roots and Rhizomes2086-83-1HighWell-studied for supporting healthy blood glucose and lipid metabolism; may help maintain normal gut microbial balance. Multiple human trials available.
GalantamineGalanthamine; Reminyl; NivalinAlkaloid (Isoquinoline)Snowdrop / DaffodilGalanthus spp.Bulbs357-70-0HighA clinically approved acetylcholinesterase inhibitor used medically to support cognitive function in Alzheimer's disease.
Papaverine1-[(3,4-Dimethoxyphenyl)methyl]-6,7-dimethoxyisoquinolineAlkaloid (Isoquinoline)Opium PoppyPapaver somniferumCapsule Latex58-74-2HighA clinically used smooth muscle relaxant that dilates blood vessels; used medically for vascular spasm under supervision.
NoscapineNarcotine; l-NoscapineAlkaloid (Isoquinoline)Opium PoppyPapaver somniferumCapsule Latex128-62-1HighA non-addictive antitussive alkaloid used clinically to suppress dry cough without significant CNS depression.
Emetine2-Ethyl-3-(3,4-dimethoxybenzyl)-9,10-dimethoxy-1,2,3,4-tetrahydroisoquinolineAlkaloid (Isoquinoline)IpecacCephaelis ipecacuanhaRoots and Rhizomes483-18-1ModerateHistorically used as an amoebicidal agent; at low doses acts as an expectorant. High doses are emetic. Subject to strict dosing due to cardiotoxicity risk.
SanguinarinePseudochelerythrine; 13-Methylbenzo[g]benzofuro[3,2-b]quinoliniumAlkaloid (Isoquinoline)BloodrootSanguinaria canadensisRhizome2447-54-3ModerateStudied for antimicrobial and antiplaque properties at low concentrations; notable cytotoxicity limits internal use.
TetrahydropalmatineL-THP; Corydalis alkaloid; dl-TetrahydropalmatineAlkaloid (Isoquinoline)CorydalisCorydalis yanhusuoRhizome10097-84-4ModerateStudied for analgesic and mild sedative properties; may support sleep quality and pain management. Used in traditional Chinese medicine.
Hydrastinebeta-Hydrastine; Isoquinoline alkaloidAlkaloid (Isoquinoline)GoldensealHydrastis canadensisRhizome118-08-1ModerateStudied for its astringent and haemostatic properties; may support mucosal tissue health at appropriate doses.
CanadineL-Tetrahydroberberine; (R,S)-CanadineAlkaloid (Isoquinoline)GoldensealHydrastis canadensisRhizome522-97-4ModerateStudied for sedative and analgesic properties; may offer neuroprotective support in early-stage research.
Coptisine5,6-Dihydro-9,10-dimethoxy-1,3-dioxolo[4,5-g]isoquinoliniumAlkaloid (Isoquinoline)GoldthreadCoptis chinensisRhizome6020-18-4ModerateStudied for antimicrobial and antiviral properties in laboratory settings; supports the traditional use of goldthread in digestive health.
PalmatinePalmatine chloride; FibrauretinAlkaloid (Isoquinoline)Amur Cork TreePhellodendron amurenseBark3486-67-7ModerateStudied for antimicrobial and blood glucose-supporting properties; closely related structurally to berberine.
JatrorrhizineJateorhizine; VillanovineAlkaloid (Isoquinoline)BarberryBerberis vulgarisRoot Bark3621-38-3ModerateStudied for antifungal and hepatoprotective properties in preclinical models; part of the berberine-type alkaloid family.
Corydalined-Corydaline; Isoquinoline alkaloidAlkaloid (Isoquinoline)CorydalisCorydalis yanhusuoRhizome / Tuber518-69-4ModerateStudied for analgesic properties in animal models; may contribute to the pain-management activity of Corydalis preparations.
ChelidonineChelidonium alkaloid; Major alkaloid of CelandineAlkaloid (Isoquinoline)Greater CelandineChelidonium majusRoots / Sap476-32-4ModerateStudied for antispasmodic and choleretic effects; may support bile flow and digestive tract muscle relaxation at appropriate doses.
ProtopineFumarine; MacleyineAlkaloid (Isoquinoline)FumitoryFumaria officinalisAerial Parts130-86-9ModerateStudied for antispasmodic effects on smooth muscle; may contribute to the digestive-soothing properties of fumitory preparations.
CephaelineIpecac alkaloid; 2'-DesmethylemetineAlkaloid (Isoquinoline)IpecacCephaelis ipecacuanhaRoots483-17-0ModerateA potent emetic agent and amoebicide; contributes to the medicinal activity of ipecac alongside emetine.
LaudanosineLaudanum alkaloid; N-MethyltetrahydropapaverineAlkaloid (Isoquinoline)Opium PoppyPapaver somniferumCapsule Latex2688-77-9EmergingA minor opiate alkaloid studied in toxicological research; at high doses associated with CNS excitation. Not used therapeutically.
LaudanineIsoquinoline alkaloid; Laudanum constituentAlkaloid (Isoquinoline)Opium PoppyPapaver somniferumCapsule Latex301-21-3EmergingA minor alkaloid studied in pharmacognosy; closely related to laudanosine with mild dopaminergic interactions.
NeopineBeta-Codeine; 6-Deoxy-codeineAlkaloid (Isoquinoline)Opium PoppyPapaver somniferumCapsule Latex467-14-1EmergingA codeine isomer studied as a mild antitussive with low dependence potential; primarily of pharmacognostic interest.
ThebaineParamorphine; Codeine methyl enol etherAlkaloid (Isoquinoline)Opium PoppyPapaver somniferumCapsule Latex115-37-7HighA toxic stimulant opiate alkaloid used industrially as a pharmaceutical precursor for opioid analgesics and antagonists including naloxone.
PseudomorphineDehydromorphine dimerAlkaloid (Isoquinoline)Opium PoppyPapaver somniferumCapsule Latex125-24-6EmergingAn oxidative dimer of morphine with no significant opioid receptor activity; of interest primarily in forensic and analytical chemistry.
Reticuline(R,S)-Norcoclaurine-derived; MIA precursorAlkaloid (Isoquinoline)Opium PoppyPapaver somniferumCapsule Latex18797-79-0EmergingThe central biosynthetic precursor from which the plant derives most of its complex benzylisoquinoline alkaloids; studied extensively in metabolic engineering.
PorphyroxineIsoquinoline alkaloid; Opium minorAlkaloid (Isoquinoline)Opium PoppyPapaver somniferumCapsule Latex4017-67-2EmergingA minor reactive opiate constituent; primarily referenced in forensic chemistry for identification of opium-derived preparations.
CryptopineIsoquinoline alkaloidAlkaloid (Isoquinoline)Opium PoppyPapaver somniferumCapsule Latex482-74-6EmergingA minor opium alkaloid that may contribute mild sedative and cardiac slowing effects at high doses; primarily of research interest.
NarceineNarcosine; Narceine hydrateAlkaloid (Isoquinoline)Opium PoppyPapaver somniferumCapsule Latex131-28-2ModerateA non-addictive opium alkaloid with mild antitussive properties; studied for its calming effect on the respiratory mucosa.
ColumbamineColumbamine chloride; Yellow dye alkaloidAlkaloid (Isoquinoline)GoldensealHydrastis canadensisRhizome3621-36-1ModerateStudied for its potential to support intestinal mucosal barrier integrity and modulate gut inflammatory responses.
WorenineCoptis alkaloid; Yellow pigmentAlkaloid (Isoquinoline)GoldthreadCoptis chinensisRhizome6873-09-2ModerateStudied for broad-spectrum antimicrobial activity including against drug-resistant gut pathogens.
Epiberberine13-Epi-berberineAlkaloid (Isoquinoline)GoldthreadCoptis chinensisRhizome6873-15-0ModerateStudied for effects on hepatic lipid metabolism; may help regulate fat accumulation in liver tissue.
GroenlandicineCoptis alkaloid; Isoquinoline pigmentAlkaloid (Isoquinoline)GoldthreadCoptis chinensisRhizome6873-13-8EmergingStudied for neuroprotective potential; preliminary research suggests it may help protect nerve cells from oxidative stress-induced damage.
Bulbocapnine(+)-Bulbocapnine; Aporphine alkaloidAlkaloid (Isoquinoline)CorydalisCorydalis cavaTuber298-45-3ModerateStudies for effects on motor function and vestibular disturbances; historically researched for its dopamine-receptor interactions.
Oripavine14-Hydroxycodeinone precursor; Opium alkaloidAlkaloid (Isoquinoline)Opium PoppyPapaver somniferumCapsule Latex467-04-9ModerateA highly potent opiate alkaloid used as a pharmaceutical precursor to produce buprenorphine and other advanced opioid medications.
StrictosidineIsovincoside; Universal MIA precursorAlkaloid (Indole)Madagascar PeriwinkleCatharanthus roseusLeaves22255-40-9EmergingThe universal biosynthetic precursor from which the plant assembles all of its complex monoterpenoid indole alkaloids; of central interest in metabolic engineering research.
PsychotrineIpecac minor alkaloidAlkaloid (Isoquinoline)IpecacCephaelis ipecacuanhaRoots20001-63-4EmergingA minor ipecac constituent that may contribute to the plant's amoebicidal activity alongside emetine and cephaeline.
INDOLE ALKALOIDS
VincristineLeurocristine; VCR; OncovinAlkaloid (Indole)Madagascar PeriwinkleCatharanthus roseusAerial Parts57-22-7HighA clinically approved vinca alkaloid used medically in cancer chemotherapy, particularly for leukaemia; administered under medical supervision only.
VinblastineVincaleukoblastine; VLB; VelbanAlkaloid (Indole)Madagascar PeriwinkleCatharanthus roseusAerial Parts865-21-4HighA clinically approved vinca alkaloid used medically in cancer chemotherapy; inhibits microtubule formation during cell division.
ReserpineSerpasil; RaudixinAlkaloid (Indole)Indian SnakerootRauvolfia serpentinaDried Roots50-55-5HighA clinically established antihypertensive and antipsychotic that depletes catecholamine stores; now largely superseded by newer drugs due to side effect profile.
AjmalineCardiorythmine; GilurytmalAlkaloid (Indole)Indian SnakerootRauvolfia serpentinaDried Roots4360-12-7HighA clinically used class Ia antiarrhythmic; administered under medical supervision for ventricular arrhythmias.
Huperzine AHupA; Selagine; Huperzia alkaloidAlkaloid (Lycopodium)Toothed ClubmossHuperzia serrataWhole Plant102518-79-6ModerateStudied for acetylcholinesterase inhibition and potential support for cognitive function and memory; multiple small human trials available with promising but preliminary results.
PhysostigmineEserine; CalabarineAlkaloid (Indole)Ordeal BeanPhysostigma venenosumSeeds57-47-6HighA clinically used reversible acetylcholinesterase inhibitor; administered medically for glaucoma and as an antidote for anticholinergic poisoning.
ErgotamineErgomar; Cafergot constituentAlkaloid (Indole)Ergot FungusClaviceps purpureaSclerotium113-15-5HighA clinically established vasoconstrictor used medically for acute migraine management; associated with ergotism risk at high doses.
VincamineVincamone; OxicebralAlkaloid (Indole)Lesser PeriwinkleVinca minorLeaves1617-90-9ModerateStudied for its potential to improve cerebral blood flow; may support cognitive function in age-related decline, with limited clinical trial data.
IbogaineIbogaine HCl; Tabernanthe alkaloidAlkaloid (Indole)IbogaTabernanthe ibogaRoot Bark83-74-9EmergingStudied for potential to interrupt addiction pathways, particularly for opioid and alcohol dependence; associated with serious cardiac risks and altered sensory perception. Controlled substance in most jurisdictions.
HarmineTelepathine; Leucoharmine; Syrian Rue alkaloidAlkaloid (Indole)Syrian RuePeganum harmalaSeeds442-51-3ModerateA reversible monoamine oxidase inhibitor (MAOI); studied for effects on neuroplasticity, mood, and potential neuroprotective activity. Psychoactive at higher doses.
Harmaline3,4-Dihydroharmine; beta-carbolineAlkaloid (Beta-carboline)Syrian RuePeganum harmalaSeeds304-21-2ModerateA short-acting reversible MAOI studied for potential neurological effects; alters neurotransmitter metabolism. Psychoactive at higher doses.
TetrahydroharmineTHH; LeptaflorineAlkaloid (Beta-carboline)Ayahuasca VineBanisteriopsis caapiStem / Bark7629-35-8EmergingStudied for weak serotonin reuptake inhibitory activity; contributes to the pharmacological profile of ayahuasca preparations alongside MAOIs.
Harmalol3,4-Dihydro-1-methyl-beta-carbolineAlkaloid (Beta-carboline)Syrian RuePeganum harmalaSeeds304-20-1EmergingA minor beta-carboline studied for antioxidant and potential neuroprotective properties in early-stage laboratory research.
Harmol1-Methyl-beta-carboline; Harmine metaboliteAlkaloid (Beta-carboline)Syrian RuePeganum harmalaSeeds487-03-6EmergingA beta-carboline studied for muscle relaxant properties in animal models; minor constituent of Syrian rue with mild CNS activity.
CatharanthineIboga-type alkaloid; Vinca precursorAlkaloid (Indole)Madagascar PeriwinkleCatharanthus roseusLeaves2468-21-5ModerateA biosynthetic precursor alkaloid that combines with vindoline to form dimeric vinca alkaloids; studied in metabolic engineering for anticancer compound production.
VindolineVinca alkaloid monomerAlkaloid (Indole)Madagascar PeriwinkleCatharanthus roseusLeaves2182-14-1ModerateA monomeric precursor that combines biosynthetically with catharanthine to produce the clinically important vincristine and vinblastine.
RescinnamineModeril; Rauvolfia alkaloidAlkaloid (Indole)Indian SnakerootRauvolfia serpentinaRoots24815-24-5ModerateA Rauvolfia alkaloid with antihypertensive properties; studied for its ability to reduce blood pressure by depleting peripheral noradrenaline stores.
DeserpidineCanescine; HarmonylAlkaloid (Indole)Indian SnakerootRauvolfia serpentinaRoots131-01-1ModerateAn antihypertensive and tranquilising Rauvolfia alkaloid related to reserpine; historically used clinically for hypertension management.
SerpentineRauvolfia alkaloid; CNS depressantAlkaloid (Indole)Indian SnakerootRauvolfia serpentinaDried Roots18786-24-8ModerateA companion alkaloid to reserpine in Rauvolfia; studied for its CNS depressant and hypotensive properties.
RauwolscineAlpha-Yohimbine; IsoyohimbineAlkaloid (Indole)Indian SnakerootRauvolfia serpentinaRoots131-03-3ModerateStudied as an alpha-2 adrenergic receptor antagonist; may support fat mobilisation and mildly elevate sympathetic nervous tone.
SarpagineRauvolfia alkaloid; Indole precursorAlkaloid (Indole)Indian SnakerootRauvolfia serpentinaRoots6752-54-1EmergingA foundational indole alkaloid in Rauvolfia; studied as a biosynthetic scaffold for the plant's antihypertensive alkaloid family.
VellosimineRauvolfia minor alkaloidAlkaloid (Indole)Indian SnakerootRauvolfia serpentinaRoots6886-97-1EmergingA minor sedative alkaloid in the Rauvolfia complex; contributes to the plant's overall CNS-modulatory activity.
AricineRauvolfia alkaloidAlkaloid (Indole)Indian SnakerootRauvolfia serpentinaRoots482-63-3EmergingStudied for its contribution to the antihypertensive effect of Rauvolfia by supporting depletion of norepinephrine reserves.
AjmalicidineRauvolfia minor alkaloidAlkaloid (Indole)Indian SnakerootRauvolfia serpentinaRoots6877-33-4EmergingStudied in early-stage research for potential effects on cerebral blood flow and age-related cognitive support.
SeredamineRauvolfia serotonin modulatorAlkaloid (Indole)Indian SnakerootRauvolfia serpentinaRootsEmergingStudied for serotonin receptor interactions; contributes to the complex neurological pharmacology of Rauvolfia root preparations.
PelirineRauvolfia minor alkaloidAlkaloid (Indole)Indian SnakerootRauvolfia serpentinaRootsEmergingA minor alkaloid supporting the overall antihypertensive and sedative profile of the Rauvolfia alkaloid complex.
Gramine3-(Dimethylaminomethyl)indole; DonaxineAlkaloid (Indole)Giant ReedArundo donaxLeaves87-52-5EmergingA tryptamine-derived indole alkaloid studied for smooth muscle effects; associated with vasoconstriction in animal studies.
Brucine2,3-Dimethoxystrychnidin-10-oneAlkaloid (Indole)Strychnine TreeStrychnos nux-vomicaSeeds357-57-3EmergingA highly toxic glycine receptor antagonist related to strychnine; studied in toxicology. Not therapeutically used. Severe CNS toxicity at very low doses.
VomicineStrychnidin-10-one derivativeAlkaloid (Indole)Strychnine TreeStrychnos nux-vomicaSeeds125-15-5EmergingA highly toxic Strychnos alkaloid associated with severe CNS excitation and convulsions; documented for toxicological reference only.
StrychnineStrychnidin-10-one; Nux vomica alkaloidAlkaloid (Indole)Strychnine TreeStrychnos nux-vomicaDried Seeds57-24-9EmergingA potent glycine antagonist causing CNS hyperexcitability; historically used in sub-toxic doses as a tonic. Associated with severe toxicity — documented for reference only.
MitragynineMitrajavine; Kratom major alkaloidAlkaloid (Indole)KratomMitragyna speciosaLeaves4098-40-2ModerateThe primary alkaloid of kratom; studied for partial opioid receptor agonism and potential analgesic activity. Subject to ongoing regulatory review and dependence concerns.
7-Hydroxymitragynine7-OH-Mitragynine; Kratom minor alkaloidAlkaloid (Indole)KratomMitragyna speciosaLeaves174418-82-7ModerateA potent minor kratom alkaloid with higher opioid receptor affinity than mitragynine; studied for analgesic effects but associated with dependence risk.
SpeciociliatineKratom minor alkaloidAlkaloid (Indole)KratomMitragyna speciosaLeaves4098-41-3EmergingA minor kratom alkaloid studied for distinct receptor binding; may contribute muscle-relaxant and analgesic components to the overall kratom pharmacological profile.
CorynoxineKratom / Cat's Claw alkaloidAlkaloid (Indole)Kratom / Cat's ClawMitragyna speciosaLeaves / BarkEmergingStudied in early-stage research for potential neuroprotective activity related to autophagy induction and protein clearance in neural tissue.
RhynchophyllineUncaria tetracyclic alkaloidAlkaloid (Indole)Cat's ClawUncaria tomentosaInner Bark76-66-4ModerateStudied for calcium channel blocking activity and potential cardiovascular and neuroprotective effects; may support healthy blood pressure.
IsorhynchophyllineUncaria alkaloid; Tetracyclic oxindoleAlkaloid (Indole)Cat's ClawUncaria tomentosaInner BarkEmergingStudied for neuroprotective properties in hypoxic conditions; early-stage research suggests potential support for neuronal survival.
YohimbineAphrodine; Quebrachine; CorynineAlkaloid (Indole)YohimbePausinystalia yohimbeBark146-48-5ModerateAn alpha-2 adrenergic antagonist studied for effects on fat mobilisation and sexual function; associated with cardiovascular and anxiety side effects at higher doses.
CorynantheineYohimbe alkaloid; Indole alkaloidAlkaloid (Indole)YohimbePausinystalia yohimbeBark6877-32-3EmergingStudied for vascular receptor-blocking activity; may contribute to the blood flow-modulating properties of yohimbe bark alongside yohimbine.
CorynanthineAlpha-Yohimbine isomer; RauhimbineAlkaloid (Indole)YohimbePausinystalia yohimbeBark483-10-3ModerateStudied as an alpha-1 adrenergic antagonist; may contribute to vasodilatory and blood pressure-modulating effects of yohimbe preparations.
Yohimbinic AcidYohimbine metaboliteAlkaloid (Indole)YohimbePausinystalia yohimbeBarkEmergingThe primary inactive urinary metabolite of yohimbine; used as a biomarker in pharmacokinetic studies of yohimbe alkaloid metabolism.
AkuamminePicralima seed alkaloid; Kappa-opioid agonistAlkaloid (Indole)AkuammaPicralima nitidaSeeds4880-88-0ModerateStudied for kappa-opioid receptor agonism and potential analgesic properties; part of the traditional West African analgesic plant Akuamma.
AkuammidinePicralima alkaloidAlkaloid (Indole)AkuammaPicralima nitidaSeedsEmergingA minor alkaloid studied for mild muscle-relaxant and hypotensive properties in preclinical models.
AkuammicinePicralima opioid alkaloidAlkaloid (Indole)AkuammaPicralima nitidaSeedsEmergingStudied for opioid receptor binding and potential analgesic activity without the respiratory depression associated with classical opioids.
AkuammilinePicralima alkaloid complexAlkaloid (Indole)AkuammaPicralima nitidaSeedsEmergingStudied in early-stage research for anti-inflammatory and analgesic properties in preclinical pain models.
EchitamineDitaine; Alstonia alkaloidAlkaloid (Indole)Dita BarkAlstonia scholarisTrunk Bark478-94-4ModerateStudied for antipyretic and antispasmodic properties; used traditionally in Southeast Asian medicine for fever management.
AlstonineAlstonia alkaloid; Antipsychotic indoleAlkaloid (Indole)Dita Bark / SnakerootAlstonia scholarisBark / Roots642-18-2ModerateStudied for dopamine receptor-mediated antipsychotic-like properties in animal models; of interest in psychiatric research.
AlstonidineAlstonia minor alkaloidAlkaloid (Indole)Dita BarkAlstonia scholarisBarkEmergingA minor sedative alkaloid from Alstonia; studied for mild CNS depressant and blood pressure-lowering properties.
TetrahydroalstonineAlstonia hypoglycaemic alkaloidAlkaloid (Indole)Dita BarkAlstonia scholarisBark6877-09-4ModerateStudied for significant hypoglycaemic activity in preclinical models; may support healthy blood glucose management.
EchitamidineAlstonia alkaloidAlkaloid (Indole)Dita BarkAlstonia scholarisBarkEmergingStudied in traditional medicine contexts for antipyretic properties and electrolyte-rebalancing effects during febrile illness.
LeurosineVinca alkaloid dimer; VLRAlkaloid (Indole)Madagascar PeriwinkleCatharanthus roseusLeaves23360-92-1ModerateClosely related to vinblastine; studied for antimitotic properties. Less clinically studied than its relatives due to higher toxicity profile.
VindolinineCatharanthus minor alkaloidAlkaloid (Indole)Madagascar PeriwinkleCatharanthus roseusLeaves4490-60-6ModerateStudied for moderate hypoglycaemic activity in animal models; may contribute to the traditional use of periwinkle for blood sugar support.
CatharineVinca complex dimerAlkaloid (Indole)Madagascar PeriwinkleCatharanthus roseusLeavesEmergingA minor dimeric vinca alkaloid studied primarily in botanical mapping and natural product chemistry research.
Catharanthinic AcidVinca alkaloid intermediateAlkaloid (Indole)Madagascar PeriwinkleCatharanthus roseusLeavesEmergingA biosynthetic intermediate in the assembly of complex antimitotic vinca alkaloids; of interest in metabolic pathway engineering.
IbogamineIboga minor alkaloidAlkaloid (Indole)IbogaTabernanthe ibogaRoot Bark3484-55-7EmergingA minor iboga alkaloid studied for anticonvulsant properties in animal models; contributes to the broader neurological activity of iboga root bark.
TabernanthineIboga alkaloid; CNS depressantAlkaloid (Indole)IbogaTabernanthe ibogaRoot Bark4880-92-6EmergingStudied for heart rate-lowering and analgesic effects; a minor alkaloid of the iboga complex with lower potency than ibogaine.
IbogalineIboga minor alkaloidAlkaloid (Indole)IbogaTabernanthe ibogaRoot BarkEmergingA minor constituent of iboga root bark; contributes to the plant's complex neurological defence chemistry.
VoacangineVoacanga alkaloid; Ibogaine precursorAlkaloid (Indole)VoacangaVoacanga africanaBark / Seeds83-34-1ModerateA biosynthetic precursor used in the semi-synthesis of ibogaine and related anti-addiction compounds; studied for mild analgesic properties.
CoronaridineIboga-type alkaloidAlkaloid (Indole)VoacangaVoacanga africanaBark / Roots467-77-6ModerateStudied for analgesic properties and potential to reduce addictive drug-seeking behaviour in animal models.
ConopharyngineVoacanga alkaloidAlkaloid (Indole)VoacangaVoacanga africanaBarkEmergingA minor alkaloid from Voacanga; studied for mild CNS stimulant and vasodilatory properties in preliminary research.
Tryptamine3-(2-Aminoethyl)indole; Biogenic amineAlkaloid (Indole)Acacia / MimosaAcacia / Mimosa spp.Root Bark61-54-1ModerateA trace biogenic amine and biosynthetic precursor to numerous psychoactive tryptamine alkaloids; minor endogenous activity as a trace amine.
N,N-DMTDimethyltryptamine; PhantasticaAlkaloid (Indole)Jurema PretaMimosa tenuifloraRoot Bark61-50-7EmergingA potent serotonin receptor agonist associated with profound alterations in sensory perception; subject to controlled substance regulations in most jurisdictions.
Bufotenin5-Hydroxy-DMT; N,N-Dimethyl-5-hydroxytryptamineAlkaloid (Indole)Yopo TreeAnadenanthera colubrinaSeeds487-93-4EmergingA serotonergic alkaloid associated with intense cardiovascular stimulation and significant perceptual alterations; subject to controlled substance regulations.
5-MeO-DMT5-Methoxy-N,N-dimethyltryptamineAlkaloid (Indole)VirolaVirola theiodoraBark Resin1019-45-0EmergingAn extremely potent serotonin agonist associated with complete dissociative states; subject to controlled substance regulations in most jurisdictions.
ErvamineTabernaemontana alkaloidAlkaloid (Indole)Crepe JasmineTabernaemontana divaricataLeavesEmergingStudied for acetylcholinesterase inhibitory properties in early-stage research; may contribute to the cognitive-supportive traditional uses of this plant.
ErvatamineCrepe Jasmine alkaloidAlkaloid (Indole)Crepe JasmineTabernaemontana divaricataLeavesEmergingStudied for significant CNS depressant activity in animal models; associated with hypothermia at higher doses in preclinical research.
MacusineCurare alkaloid; Strychnos alkaloidAlkaloid (Indole)Strychnine TreeStrychnos toxiferaBarkEmergingA curare-type alkaloid that blocks neuromuscular junction transmission; of historical interest in anaesthesiology research.
C-ToxiferineCalabash curare; Neuromuscular blockerAlkaloid (Indole)Strychnine TreeStrychnos toxiferaBark4759-48-2EmergingOne of the most potent plant-derived neuromuscular blockers; associated with respiratory paralysis at very low doses. Studied historically in anaesthesia pharmacology.
StrychnobrasilineSouth American Strychnos alkaloidAlkaloid (Indole)Strychnine TreeStrychnos brasiliensisBarkEmergingStudied for a complex mix of local muscle-relaxant and mild CNS excitatory effects in preclinical models.
KoumineGelsemium minor alkaloidAlkaloid (Indole)Yellow JessamineGelsemium elegansRoots1358-76-5EmergingStudied for non-opioid analgesic properties in animal pain models; associated with promising but early-stage results for chronic pain management.
GelsevirineGelsemium toxic alkaloidAlkaloid (Indole)Yellow JessamineGelsemium sempervirensRoots1354-84-3EmergingA highly toxic alkaloid that depresses respiratory centres; documented for toxicological reference. Associated with serious poisoning risk.
SempervirineGelsemium alkaloidAlkaloid (Indole)Yellow JessamineGelsemium sempervirensRoots6893-02-3EmergingStudied for potential spinal analgesic properties; high systemic toxicity limits clinical development.
Mescaline3,4,5-Trimethoxyphenethylamine; Peyote alkaloidAlkaloid (Protoalkaloid)Peyote / San PedroLophophora williamsiiCactus Button54-04-6EmergingA phenethylamine psychedelic studied for interactions with serotonin receptors; associated with profound alterations in perception and cognition. Controlled substance in most jurisdictions.
SecurinineNorsecurinine; Phyllanthus alkaloidAlkaloid (Indolizidine)SecurinegaSecurinega suffruticosaLeaves / Roots5610-40-2ModerateA GABA antagonist studied for CNS stimulant effects and potential support in neurological fatigue conditions; used in traditional Chinese medicine.
AustralineCassia alkaloid; Swainsonine analogAlkaloid (Pyrrolizidine)Moreton Bay ChestnutCastanospermum australeSeeds107439-79-2EmergingStudied for selective glycosidase inhibitory activity with potential antiviral applications; part of the indolizidine alkaloid family with distinct properties from hepatotoxic pyrrolizidines.
LentiginosineLocoweed alkaloid; Castanospermine analogAlkaloid (Indolizidine)LocoweedAstragalus lentiginosusLeavesEmergingA specialised glycosidase inhibitor studied for antiviral potential; of interest in cell biology research for its effects on glycoprotein processing.
LycorineLycoris alkaloid; Narcissus alkaloidAlkaloid (Amaryllidaceae)Spider LilyLycoris radiataBulbs476-28-8ModerateStudied for emetic, antiviral, and antiproliferative properties in preclinical models; associated with moderate cytotoxicity at higher doses.
NarciclasineNarcissus alkaloid; Growth inhibitorAlkaloid (Amaryllidaceae)DaffodilNarcissus spp.Bulbs29477-83-6EmergingStudied for antiproliferative and antifungal properties in laboratory settings; associated with potent phytotoxic activity.
HaemanthamineBlood Lily alkaloidAlkaloid (Amaryllidaceae)Blood LilyHaemanthus spp.Bulbs466-75-1EmergingStudied in early-stage research for its ability to trigger apoptosis in cancer cell lines; preclinical data only.
TazettineNarcissus alkaloidAlkaloid (Amaryllidaceae)DaffodilNarcissus tazettaBulbs15210-24-9EmergingA mildly cytotoxic Narcissus alkaloid studied for effects on cellular life cycles in laboratory research.
CrinineCrinum alkaloidAlkaloid (Amaryllidaceae)Crinum LilyCrinum asiaticumBulbs480-27-3EmergingStudied for respiratory stimulant properties in traditional medicine contexts; of research interest for its effects on CNS respiratory centres.
NuciferineLotus leaf alkaloid; AporphineAlkaloid (Aporphine)Sacred LotusNelumbo nuciferaLeaves475-83-2ModerateStudied for CNS relaxant, antipsychotic-like, and hepatoprotective (lipid-clearing) properties in preclinical research.
NeferineLotus seed embryo alkaloidAlkaloid (Bisbenzylisoquinoline)Sacred LotusNelumbo nuciferaSeed Embryo2292-16-2ModerateStudied for calcium channel blocking, antihypertensive, and potential pulmonary antifibrotic properties in preclinical models.
RoemerineLotus aporphine alkaloidAlkaloid (Aporphine)Sacred LotusNelumbo nuciferaLeavesEmergingStudied for antifungal and antimicrobial properties in laboratory settings; contributes to the broader pharmacological profile of lotus leaf preparations.
MagnoflorineMagnolia quaternary alkaloidAlkaloid (Aporphine)MagnoliaMagnolia officinalisBark6873-13-8ModerateStudied for anxiolytic, cholesterol-oxidation-inhibiting, and anti-neuroinflammatory properties in preclinical models.
Boldine(+)-Boldine; Peumus alkaloidAlkaloid (Aporphine)BoldoPeumus boldusDried Leaves476-70-0ModerateStudied for hepatoprotective, choleretic, and antioxidant properties; supports traditional use for liver and gallbladder health.
IsocorydineGlaucium aporphine alkaloidAlkaloid (Aporphine)Yellow Horned PoppyGlaucium flavumAerial Parts475-67-2EmergingStudied for vasodilatory and antiproliferative properties in early-stage research; contributes to the traditional use of Glaucium for pain.
CorytuberineCorydalis aporphine alkaloidAlkaloid (Aporphine)CorydalisCorydalis yanhusuoTuber522-89-4EmergingStudied for strong dopaminergic effects including rigid muscle states in animal models; contributes to the complex pharmacology of Corydalis preparations.
CorydineCorydalis aporphine; CNS depressantAlkaloid (Aporphine)CorydalisCorydalis yanhusuoTuber476-69-7ModerateStudied for analgesic and CNS depressant properties; contributes to the traditional pain-management use of Corydalis alongside THP.
LaurotetanineLitsea aporphine alkaloidAlkaloid (Aporphine)LitseaLitsea cubebaBark / Roots6877-32-3EmergingStudied for antimicrobial and CNS depressant properties in early-stage laboratory research.
LiriodenineTulip tree alkaloid; OxoaporphineAlkaloid (Aporphine)Tulip TreeLiriodendron tulipiferaHeartwood522-59-8ModerateStudied for antimicrobial and antifungal properties; associated with inhibitory effects on fungal cell wall synthesis.
ThalicarpineMeadow Rue aporphineAlkaloid (Aporphine)Meadow RueThalictrum dasycarpumRootsEmergingStudied in early-stage laboratory research for antiproliferative effects on cancer cell lines; preclinical data only.
HernandalineHernandia aporphine alkaloidAlkaloid (Aporphine)HernandiaHernandia nymphaeifoliaBark / LeavesEmergingStudied for smooth muscle relaxant and antihypertensive properties in animal models.
LysicamineLiriodendron oxoaporphineAlkaloid (Aporphine)Tulip TreeLiriodendron tulipiferaHeartwoodEmergingStudied for antifungal and antibacterial properties against soil-borne pathogens in laboratory research.
NandigerineNandina aporphine alkaloidAlkaloid (Aporphine)Heavenly BambooNandina domesticaBerries / RootsEmergingStudied for bronchodilatory effects; associated with significant systemic toxicity if ingested in quantity. Documented for safety reference.
AtherospermidineSassafras aporphine alkaloidAlkaloid (Aporphine)SassafrasSassafras albidumRoots / BarkEmergingStudied for cytotoxic properties in targeted cell line research; preclinical data only.
AnonaineCustard Apple aporphineAlkaloid (Aporphine)Custard AppleAnnona squamosaBark / LeavesEmergingStudied in early-stage laboratory research for antiproliferative effects on cancer cell lines.
TetrandrineSinomenine-related; BisbenzylisoquinolineAlkaloid (Bisbenzylisoquinoline)StephaniaStephania tetrandraRoots518-34-3ModerateStudied for calcium channel blocking, antihypertensive, and anti-inflammatory properties; multiple preclinical studies and limited human trials for lung conditions.
FangchinolineStephania alkaloidAlkaloid (Bisbenzylisoquinoline)StephaniaStephania tetrandraRoots33889-69-9ModerateStudied for anticoagulant and antiviral properties in preclinical models; may complement the pharmacological profile of Stephania root.
DauricineAsian Moonseed alkaloidAlkaloid (Bisbenzylisoquinoline)Asian MoonseedMenispermum dauricumRhizomes524-17-4ModerateStudied for antiarrhythmic properties and potential protection of cardiac tissue during ischaemic stress; preclinical data available.
ThalidasineMeadow Rue bisbenzylAlkaloid (Bisbenzylisoquinoline)Meadow RueThalictrum dasycarpumRootsEmergingStudied for potential anti-angiogenic properties that may limit blood supply to tumour tissue; early-stage laboratory research only.
IsochondodendrineCurare-related alkaloidAlkaloid (Bisbenzylisoquinoline)Curare VineChondrodendron tomentosumBark6871-44-9EmergingA structural relative of tubocurarine studied for mild non-lethal neuromuscular relaxant properties; of historical pharmacological interest.
ChondrocurarineTubocurarine-type; Curare alkaloidAlkaloid (Bisbenzylisoquinoline)Curare VineChondrodendron tomentosumBarkEmergingA potent neuromuscular blocking alkaloid; associated with respiratory paralysis. Documented for toxicological and pharmacological reference only.
CissampareineCissampelos bisbenzylAlkaloid (Bisbenzylisoquinoline)VelvetleafCissampelos pareiraRootsEmergingStudied for uterine smooth muscle relaxant properties; of interest for research into preterm labour management. Preclinical data only.
StepholidineStephania protoberberineAlkaloid (Protoberberine)StephaniaStephania intermediaRoots / TubersModerateStudied for dopamine D1/D2 receptor modulation; of interest in research into movement disorders and antipsychotic pharmacology.
TROPANE ALKALOIDS
Atropinedl-Hyoscyamine; dl-Tropyl tropateAlkaloid (Tropane)Deadly NightshadeAtropa belladonnaLeaves and Roots51-55-8HighA clinically established anticholinergic used medically as a pre-anaesthetic, antispasmodic, and antidote to organophosphate poisoning.
ScopolamineHyoscine; Transderm ScopAlkaloid (Tropane)Jimson WeedDatura stramoniumSeeds and Leaves51-34-3HighA clinically established anticholinergic used medically for motion sickness, pre-anaesthetic sedation, and nausea management.
CocaineBenzoylmethylecgonine; CokeAlkaloid (Tropane)CocaErythroxylum cocaLeaves50-36-2HighA potent local anaesthetic and sympathomimetic; the first clinically used local anaesthetic. Associated with significant addiction and cardiovascular toxicity. Controlled substance.
HyoscyamineL-Hyoscyamine; LevsinAlkaloid (Tropane)HenbaneHyoscyamus nigerLeaves101-31-5HighA clinically used anticholinergic that relieves smooth muscle spasms of the gastrointestinal and urinary tracts.
EcgonineCocaine backbone; Tropane acidAlkaloid (Tropane)CocaErythroxylum cocaLeaves481-37-8EmergingThe primary structural core of cocaine; lacks potent CNS stimulant activity on its own. Of interest in forensic toxicology.
CinnamoylcocaineCoca minor alkaloidAlkaloid (Tropane)CocaErythroxylum cocaLeaves521-64-2EmergingA secondary coca alkaloid with mild local anaesthetic and stimulant properties; contributes to the complex alkaloid profile of coca leaf.
TropacocaineCoca minor alkaloidAlkaloid (Tropane)CocaErythroxylum cocaLeaves537-26-8EmergingStudied for local anaesthetic properties with a faster onset but shorter duration than cocaine; of primarily pharmacological research interest.
PseudotropineTropine isomer; Tropane precursorAlkaloid (Tropane)Deadly NightshadeAtropa belladonnaRoots135-97-7EmergingA biosynthetic intermediate in the production of tropane alkaloids; lacks the potent pharmacological activity of atropine or scopolamine.
BelladonnineAtropa minor alkaloidAlkaloid (Tropane)Deadly NightshadeAtropa belladonnaLeavesEmergingA minor tropane alkaloid from Atropa belladonna; associated with strong mydriatic and smooth muscle-paralysing effects at low doses. Toxic — documented for reference.
Calystegine A3Polyhydroxy tropane; IminosugarAlkaloid (Tropane)Potato / BindweedSolanum tuberosumRoots / Tubers117275-05-5EmergingStudied as a glycosidase inhibitor that may influence carbohydrate metabolism; present at trace levels in common dietary plants.
PURINE ALKALOIDS
Caffeine1,3,7-Trimethylxanthine; GuaranineAlkaloid (Purine)Coffee / Tea PlantCoffea arabica / Camellia sinensisDried Seeds / Leaves58-08-2HighAn adenosine receptor antagonist that increases alertness and reduces fatigue; well-documented in human trials for cognitive and physical performance support.
Theobromine3,7-Dimethylxanthine; Cacao alkaloidAlkaloid (Purine)CacaoTheobroma cacaoSeeds (Beans)83-67-0HighA mild CNS stimulant and bronchodilator; studied for cardiovascular effects including vasodilation and positive inotropic activity. Lower CNS potency than caffeine.
Theophylline1,3-Dimethylxanthine; Aminophylline precursorAlkaloid (Purine)Tea PlantCamellia sinensisLeaves58-55-9HighA clinically used bronchodilator for asthma and COPD management; relaxes airway smooth muscle via phosphodiesterase inhibition.
MethylliberineDynamine; Kucha tea alkaloidAlkaloid (Purine)Kucha TeaCamellia assamicaLeavesEmergingStudied for rapid-onset CNS stimulation with a potentially lower cardiovascular burden than caffeine; early-stage human research is limited.
Paraxanthine1,7-Dimethylxanthine; Caffeine metaboliteAlkaloid (Purine)CoffeeCoffea arabicaSeeds611-59-6ModerateThe primary human metabolic product of caffeine; studied for lipolytic and muscular endurance-enhancing properties independent of caffeine.
PYRIDINE & PIPERIDINE ALKALOIDS
Nicotine3-(1-Methylpyrrolidin-2-yl)pyridine; Tabacum alkaloidAlkaloid (Pyridine)TobaccoNicotiana tabacumLeaves54-11-5HighAn acetylcholinergic stimulant; pharmacologically well-characterised. Associated with significant cardiovascular and addictive effects. Controlled in many jurisdictions.
Piperine1-Piperoylpiperidine; Black Pepper amideAlkaloid (Piperidine)Black PepperPiper nigrumDried Fruits94-62-2HighWell-documented as a bioavailability enhancer; may inhibit P-glycoprotein and CYP3A4 to increase absorption of co-administered compounds including curcumin.
LobelineLobelamine; Lobelia alkaloidAlkaloid (Piperidine)Indian TobaccoLobelia inflataDried Whole Plant90-69-7ModerateStudied as a nicotinic receptor partial agonist; historically used as a smoking cessation aid and expectorant. Limited modern clinical evidence.
ArecolineBetel nut alkaloid; Methyl arecaidinateAlkaloid (Pyridine)Betel NutAreca catechuSeeds63-75-2ModerateA muscarinic and nicotinic agonist producing CNS stimulation; associated with significant long-term cardiovascular and oral carcinogenicity risks with habitual use.
GuvacineGABA reuptake inhibitor; Betel nut alkaloidAlkaloid (Pyridine)Betel NutAreca catechuSeedsEmergingA GABA transporter inhibitor that may produce mild CNS stimulation and nervous tension; contributes to the overall pharmacology of betel nut chewing.
Anabasinebeta-Pyridyl piperidine; Tree tobaccoAlkaloid (Pyridine)Tree TobaccoNicotiana glaucaLeaves494-52-0ModerateA botanical nicotinic receptor agonist with insecticidal properties; associated with toxicity in mammals at higher doses.
AnatabineMinor tobacco alkaloidAlkaloid (Pyridine)TobaccoNicotiana tabacumLeaves581-49-7ModerateStudied for anti-inflammatory properties in preclinical models; may support neurological pathway protection. Limited human data available.
TrigonellineN-Methylnicotinic acid; CoffearineAlkaloid (Pyridine)FenugreekTrigonella foenum-graecumSeeds535-83-1ModerateStudied for support of healthy blood glucose metabolism and potential neuroprotective properties; present in significant amounts in coffee and fenugreek.
RicinineCastor bean alkaloid; N-methyl-3-cyano-4-methoxy-2-pyridoneAlkaloid (Pyridine)Castor BeanRicinus communisSeeds524-40-3EmergingA mildly neurotoxic plant defence alkaloid; present at low levels in castor bean. Of interest primarily in toxicology and agricultural pest control research.
PelletierinePunicine; Pomegranate root alkaloidAlkaloid (Piperidine)PomegranatePunica granatumRoot Bark4396-01-4ModerateStudied for anthelmintic (parasite-expelling) properties; historically used in traditional medicine to address intestinal parasites. Toxic at high doses.
Coniine2-Propylpiperidine; Hemlock alkaloidAlkaloid (Piperidine)Poison HemlockConium maculatumSeeds458-88-8EmergingA potent neurotoxin that causes ascending motor paralysis by blocking nicotinic acetylcholine receptors. Lethal at low doses. Documented for toxicological reference only.
PiperlonguminePiplartine; Long pepper alkaloidAlkaloid (Pyridine)Long PepperPiper longumRoots / Fruit20069-09-4EmergingStudied for selective antiproliferative effects on cancer cells via oxidative stress induction; early-stage laboratory and animal research only.
QUINOLINE ALKALOIDS
QuinineQuininum; Malaria treatmentAlkaloid (Quinoline)Cinchona TreeCinchona officinalisDried Trunk Bark130-95-0HighA clinically established antimalarial; inhibits haem polymerisation in Plasmodium. Also used medically for nocturnal leg cramps under supervision.
QuinidineQuinidex; Class Ia antiarrhythmicAlkaloid (Quinoline)Cinchona TreeCinchona officinalisTrunk Bark56-54-2HighA clinically used antiarrhythmic; stabilises cardiac electrical conduction. Administered medically under monitoring due to proarrhythmic risk.
CinchonineCinchona alkaloid; AntimalarialAlkaloid (Quinoline)Cinchona TreeCinchona pubescensTrunk Bark118-10-5ModerateAn antimalarial alkaloid that disrupts haemozoin formation in malarial parasites; less studied clinically than quinine but with a similar mechanism.
CamptothecinCPT; Camptotheca alkaloidAlkaloid (Quinoline)Happy TreeCamptotheca acuminataBark and Fruit7689-03-4HighA topoisomerase I inhibitor that formed the basis for the clinically approved anticancer drugs irinotecan and topotecan.
HydroquinineQuinine minor; Cinchona alkaloidAlkaloid (Quinoline)Cinchona TreeCinchona officinalisBark522-66-7ModerateA minor cinchona alkaloid with antimalarial properties; studied as a reference compound in Plasmodium biochemistry research.
CupreineCinchotannic alkaloidAlkaloid (Quinoline)Cinchona TreeCinchona cupreaBark524-63-0ModerateA structural relative of quinine used as a chiral organocatalyst in pharmaceutical synthesis; studied for antimalarial activity.
QuinicineQuinine thermolysis productAlkaloid (Quinoline)Cinchona TreeCinchona officinalisBarkEmergingA heat-degraded isomer of quinine with reduced antimalarial efficacy; of analytical and toxicological interest in cinchona bark preparations.
CinchonamineCinchona indole alkaloidAlkaloid (Indole)Cinchona TreeCinchona pubescensBarkEmergingA minor indole-type alkaloid from Cinchona bark with mild antimalarial and CNS properties; less studied than the major cinchona alkaloids.
DictamnineBurning Bush quinolineAlkaloid (Quinoline)Burning BushDictamnus albusRoots / Bark484-29-7ModerateStudied for smooth muscle stimulant and localised antimicrobial properties; contributes to the traditional skin and digestive uses of Dictamnus.
SkimmianineJapanese Skimmia alkaloidAlkaloid (Quinoline)Japanese SkimmiaSkimmia japonicaLeaves83-95-4ModerateStudied for CNS depressant and skeletal muscle-relaxant properties in preclinical models; contributes to the traditional calming use of Skimmia.
STEROIDAL ALKALOIDS
SolanineAlpha-Solanine; Potato glycoalkaloidAlkaloid (Steroidal)PotatoSolanum tuberosumGreen Skin / Sprouts20562-02-1ModerateA natural pesticide alkaloid toxic to insects and, at elevated levels, to humans; associated with cholinesterase inhibition and gastrointestinal distress. Levels are regulated in food potatoes.
ChaconineAlpha-Chaconine; Potato glycoalkaloidAlkaloid (Steroidal)PotatoSolanum tuberosumGreen Skin / Sprouts20562-03-2ModerateA glycoalkaloid that works in combination with solanine as a natural pest deterrent; associated with neurotoxic effects at high intake levels.
TomatineAlpha-Tomatine; Tomato glycoalkaloidAlkaloid (Steroidal)TomatoSolanum lycopersicumGreen Fruit / Leaves17406-45-0ModerateA steroidal glycoalkaloid studied for antifungal activity and potential antiproliferative effects; mildly toxic to humans at very high intake.
SolasodineSolanum steroidal alkaloid; Hormone precursorAlkaloid (Steroidal)Devil's AppleSolanum linnaeanumFruit126-17-0ModerateA steroidal alkaloid used industrially as a starting material for the synthesis of pharmaceutical steroid hormones and contraceptives.
SolamargineSolanum glycoalkaloidAlkaloid (Steroidal)Devil's AppleSolanum linnaeanumFruit6956-26-3EmergingStudied for antiproliferative and apoptosis-inducing properties in cancer cell lines in early-stage laboratory research.
SolasonineSolanum glycoalkaloidAlkaloid (Steroidal)Devil's AppleSolanum linnaeanumFruit19121-58-5EmergingStudied alongside solamargine for antimicrobial and antiproliferative properties in laboratory research.
Cyclopamine11-deoxojervine; Hedgehog inhibitorAlkaloid (Steroidal)Corn LilyVeratrum californicumRoots4449-51-8EmergingA teratogenic Hedgehog signalling pathway inhibitor; studied in oncology research as a basis for targeted cancer therapies.
JervineVeratrum teratogen; Steroidal alkaloidAlkaloid (Steroidal)Corn LilyVeratrum californicumRoots469-59-0EmergingA highly teratogenic steroidal alkaloid that disrupts CNS development; associated with serious foetal malformations. Documented for toxicological reference only.
VeratramineFalse Hellebore alkaloidAlkaloid (Steroidal)False HelleboreVeratrum virideRhizomes60-70-8EmergingHighly toxic steroidal alkaloid associated with severe cardiovascular depression and CNS toxicity. Documented for toxicological reference only.
ConessineHolarrhena alkaloid; Steroidal antibioticAlkaloid (Steroidal)KurchiHolarrhena pubescensBark546-06-5ModerateStudied for specific amoebicidal activity against Entamoeba histolytica; used traditionally for severe dysentery treatment.
HolarrhenineKurchi steroidal alkaloidAlkaloid (Steroidal)KurchiHolarrhena pubescensBarkModerateA steroidal alkaloid from the same source as conessine; studied for complementary amoebicidal properties.
PeimineFritillary steroidal alkaloidAlkaloid (Steroidal)Fritillary BulbFritillaria thunbergiiBulbs18059-10-4ModerateStudied for expectorant and mucolytic properties; supports the traditional use of Fritillary bulb in respiratory wellness.
PeiminineDelavaine; Fritillary alkaloidAlkaloid (Steroidal)Fritillary BulbFritillaria thunbergiiBulbs18059-10-4ModerateStudied for anti-inflammatory and antitussive properties; may support soothing of throat mucosal irritation.
ImperialineSipeimine; Fritillary alkaloidAlkaloid (Steroidal)Fritillary BulbFritillaria imperialisBulbs18059-10-4ModerateStudied for bronchial smooth muscle-relaxing properties; may support relief from bronchospasm in respiratory conditions.
VerticineThujifoline; Fritillary alkaloidAlkaloid (Steroidal)Fritillary BulbFritillaria verticillataBulbsModerateStudied for anti-inflammatory and immunomodulatory properties in the context of pulmonary health support.
VerticinoneFritillary alkaloidAlkaloid (Steroidal)Fritillary BulbFritillaria verticillataBulbsModerateStudied alongside verticine for antitussive and expectorant effects; used in traditional Chinese medicine for respiratory conditions.
DemissineWild potato glycoalkaloidAlkaloid (Steroidal)Wild PotatoSolanum demissumLeaves28754-79-0EmergingA defensive steroidal glycoalkaloid with insecticidal activity; mildly toxic to mammals at elevated doses.
SolanocapsineJerusalem Cherry alkaloidAlkaloid (Steroidal)Jerusalem CherrySolanum pseudocapsicumFruit13956-28-0EmergingA highly toxic steroidal alkaloid associated with severe gastrointestinal and CNS toxicity if the raw fruit is consumed; documented for safety reference.
PYRROLIZIDINE ALKALOIDS
SenecionineSenecio PA; Hepatotoxic pyrrolizidineAlkaloid (Pyrrolizidine)RagwortSenecio jacobaeaLeaves130-01-8EmergingA hepatotoxic unsaturated pyrrolizidine alkaloid; associated with irreversible veno-occlusive liver disease. Strictly a toxicological reference compound — not for therapeutic use.
MonocrotalineCrotalaria PA; Pulmonary toxinAlkaloid (Pyrrolizidine)RattleboxCrotalaria spectabilisSeeds315-22-0EmergingHighly toxic to pulmonary vascular tissue; used experimentally in research models of pulmonary arterial hypertension. Not therapeutically used.
RetrorsineSenecio genotoxinAlkaloid (Pyrrolizidine)RagwortSenecio isatideusAerial Parts480-54-6EmergingAn unsaturated pyrrolizidine alkaloid that cross-links hepatocyte DNA, preventing cell division; documented for toxicological reference only.
LasiocarpineHeliotrope PA; Liver carcinogenAlkaloid (Pyrrolizidine)HeliotropeHeliotropium europaeumLeaves303-34-4EmergingA potent hepatotoxic and genotoxic pyrrolizidine alkaloid associated with permanent liver damage and classified as a possible human carcinogen. Toxicological reference only.
SymphytineComfrey PA; HepatotoxinAlkaloid (Pyrrolizidine)ComfreySymphytum officinaleRoots22257-23-4EmergingA hepatotoxic pyrrolizidine alkaloid found in comfrey root; the reason internal comfrey preparations are subject to regulatory limits in many countries.
LycopsamineBorage PA; HepatotoxinAlkaloid (Pyrrolizidine)BorageBorago officinalisLeaves10285-07-1EmergingAn unsaturated pyrrolizidine alkaloid present in borage; associated with liver toxicity at high intake levels. Regulatory monitoring is applied to borage food products.
IntermedineComfrey PA; HepatotoxinAlkaloid (Pyrrolizidine)ComfreySymphytum officinaleRootsEmergingA pyrrolizidine alkaloid associated with hepatic veno-occlusive disease in humans following internal use; toxicological reference compound.
EchimidineEchium PA; DNA cross-linkerAlkaloid (Pyrrolizidine)Viper's BuglossEchium vulgareAerial PartsEmergingA highly hepatotoxic pyrrolizidine alkaloid associated with DNA cross-linking and liver cell death; of concern as a food contaminant in honey and herbal teas.
RiddelliineSenecio genotoxin; PAAlkaloid (Pyrrolizidine)Riddell's RagwortSenecio riddelliiWhole Plant23246-96-0EmergingA genotoxic pyrrolizidine alkaloid listed as a possible human carcinogen; documented for toxicological research reference.
HeliotrineHeliotropium PA; Liver toxinAlkaloid (Pyrrolizidine)HeliotropeHeliotropium europaeumLeaves520-69-4EmergingCauses hepatic necrosis and has been associated with human poisoning through contaminated grain. Isolated for toxicological and agricultural safety research.
PlatyphyllineSenecio antispasmodic PAAlkaloid (Pyrrolizidine)Broadleaf RagwortSenecio platyphyllusLeaves480-77-3ModerateA saturated pyrrolizidine alkaloid with relatively low hepatotoxicity compared to unsaturated congeners; studied for mild antispasmodic properties.
SenkirkineColtsfoot PA; HepatotoxinAlkaloid (Pyrrolizidine)ColtsfootTussilago farfaraLeaves2318-18-5EmergingA hepatotoxic pyrrolizidine alkaloid responsible for regulatory restrictions on internal coltsfoot use in several countries.
RosmarinineSenecio PAAlkaloid (Pyrrolizidine)SenecioSenecio rosmarinifoliusAerial PartsEmergingA pyrrolizidine alkaloid associated with disruption of cell division; monitored as an agricultural and food safety concern.
AngustifolineNarrow-leaf Lupin PAAlkaloid (Quinolizidine)Narrow-leaf LupinLupinus angustifoliusSeeds486-89-5EmergingA bitter quinolizidine alkaloid that deters insect feeding; associated with CNS depression in livestock. Present in food lupins below regulated thresholds.
QUINOLIZIDINE ALKALOIDS
MatrineSophora alkaloid; QuinolizidineAlkaloid (Quinolizidine)Ku ShenSophora flavescensDried Roots519-02-8ModerateStudied for anti-inflammatory and immunomodulatory properties; used in traditional Chinese medicine and subject to ongoing clinical investigation for liver conditions.
OxymatrineSophora N-oxide; Ku Shen alkaloidAlkaloid (Quinolizidine)Sophora RootSophora flavescensRoots16837-52-8ModerateStudied for antiviral and hepatoprotective properties; multiple Chinese clinical trials available though study quality is variable.
SophoridineSophora antitumour alkaloidAlkaloid (Quinolizidine)Sophora RootSophora flavescensRoots6882-68-4ModerateStudied for antiproliferative and anti-inflammatory properties in preclinical cancer research; of interest in Chinese oncology research.
SophoramineSophora hepatoprotective alkaloidAlkaloid (Quinolizidine)Sophora RootSophora flavescensRoots6837-24-7ModerateStudied for hepatoprotective effects during chemically induced and viral hepatic stress in animal models.
CytisineBaptitoxine; Sophorine; TabexAlkaloid (Quinolizidine)Golden Rain TreeLaburnum anagyroidesSeeds485-35-8HighA nicotinic receptor partial agonist; clinically used in Eastern Europe as a smoking cessation aid with a favourable evidence base from randomised controlled trials.
SparteineLupinidine; Scotch Broom alkaloidAlkaloid (Quinolizidine)Scotch BroomCytisus scopariusBranches90-39-1ModerateA sodium and potassium channel blocker studied for antiarrhythmic and oxytocic properties; used traditionally for obstetric support and cardiac dysrhythmia.
LupanineLupin bitter alkaloidAlkaloid (Quinolizidine)LupinLupinus albusSeeds550-90-3ModerateThe primary bitter alkaloid of lupin seeds; associated with respiratory depression at high doses. Levels are strictly reduced by debittering processes in food lupins.
AnagyrineLupin teratogen; QuinolizidineAlkaloid (Quinolizidine)LupinLupinus spp.Seeds486-89-5EmergingA teratogenic quinolizidine alkaloid associated with foetal limb defects in livestock; documented for safety reference.
N-MethylcytisineCaulophylline; Blue Cohosh alkaloidAlkaloid (Quinolizidine)Blue CohoshCaulophyllum thalictroidesRoots486-86-2ModerateA nicotinic agonist that stimulates uterine contractions; used traditionally to induce labour but associated with significant cardiovascular risk — not recommended without medical supervision.
ThermopsineFalse Lupin toxic alkaloidAlkaloid (Quinolizidine)False LupinThermopsis rhombifoliaSeeds / LeavesEmergingA highly toxic quinolizidine alkaloid associated with severe gastrointestinal and respiratory toxicity in livestock and humans. Documented for toxicological reference.
DITERPENE ALKALOIDS
AconitineAcetylbenzoylaconine; Monkshood alkaloidAlkaloid (Diterpene)MonkshoodAconitum napellusDried Roots302-27-2ModerateA potent sodium channel activator associated with severe neurotoxicity and cardiac arrhythmias at very low doses; used in trace amounts in processed traditional preparations (Aconiti Radix Praeparata) for nerve pain management under strict supervision.
MesaconitineAconite alkaloid; Aconitum carmichaeliiAlkaloid (Diterpene)MonkshoodAconitum carmichaeliiRoots2752-64-9ModerateExtremely potent neurotoxin; associated with fatal arrhythmias in raw form. Used in traditional formulations after extensive thermal processing under strict supervision.
HypaconitineAconite minor alkaloidAlkaloid (Diterpene)MonkshoodAconitum carmichaeliiRoots6900-87-4EmergingA highly toxic aconite alkaloid; associated with potent anti-inflammatory and analgesic effects at strictly controlled trace doses in traditional formulations only.
LappaconitineAconite non-narcotic analgesicAlkaloid (Diterpene)MonkshoodAconitum septentrionaleRoots32854-75-4ModerateA sodium channel blocker studied for non-opioid analgesic properties; a pharmaceutical version is used clinically in Russia for pain management.
SongorineAconitum CNS stimulant alkaloidAlkaloid (Diterpene)MonkshoodAconitum soongaricumTubers2752-65-0EmergingA unique Aconitum alkaloid with a distinctly lower toxicity profile than aconitine; studied for CNS stimulant and potential analgesic properties.
BikhaconitineHimalayan Aconite neurotoxinAlkaloid (Diterpene)Himalayan MonkshoodAconitum spicatumRootsEmergingAn extremely potent neurotoxin that persistently opens voltage-gated sodium channels; associated with rapidly fatal arrhythmias. Documented for toxicological reference only.
PseudaconitineNepal Aconite; Most toxic AconitumAlkaloid (Diterpene)Nepal AconiteAconitum feroxRoots6831-43-2EmergingOne of the most potent plant alkaloid toxins known; associated with complete respiratory paralysis at very small doses. Documented for toxicological reference only.
IndaconitineChasmanthum Aconite alkaloidAlkaloid (Diterpene)MonkshoodAconitum chasmanthumRootsEmergingA neurotoxic aconitine-type alkaloid; associated with severe peripheral and central nervous system toxicity. Documented for toxicological reference.
PROTOALKALOIDS & PHENYLETHYLAMINES
EphedrineL-Ephedrine; Ma Huang alkaloidAlkaloid (Protoalkaloid)Ma HuangEphedra sinicaGreen Twigs299-42-3HighA clinically established sympathomimetic bronchodilator and decongestant; used medically but subject to regulatory controls due to potential for misuse.
PseudoephedrineD-Pseudoephedrine; SudafedAlkaloid (Protoalkaloid)Ma HuangEphedra sinicaStems90-82-4HighA clinically used nasal decongestant that acts as a vasoconstrictive sympathomimetic; widely available as an OTC medication but regulated as a precursor.
CathineNorpseudoephedrine; D-NorpseudoephedrineAlkaloid (Protoalkaloid)KhatCatha edulisFresh Leaves492-39-7ModerateA mild sympathomimetic with appetite-suppressing effects; controlled substance in most Western jurisdictions.
CathinoneS-(-)-Cathinone; Khat primary stimulantAlkaloid (Protoalkaloid)KhatCatha edulisFresh Leaves71031-15-7ModerateThe primary psychoactive amphetamine-like alkaloid of khat; associated with significant dopaminergic stimulation and dependence risk. Controlled substance.
HordenineN,N-Dimethyltyramine; Barley alkaloidAlkaloid (Protoalkaloid)BarleyHordeum vulgareGerminating Roots539-15-1ModerateStudied for norepinephrine-releasing activity producing brief physical energy enhancement; present in germinating grains and beer.
SynephrinePara-Synephrine; Bitter orange alkaloidAlkaloid (Protoalkaloid)Bitter OrangeCitrus aurantiumFruit Peel94-07-5ModerateStudied for thermogenic and lipolytic effects; used in weight management supplements. Associated with cardiovascular effects at high doses — regulatory caution applies.
ColchicineColchicum alkaloid; NSF inhibitorAlkaloid (Protoalkaloid)Autumn CrocusColchicum autumnaleSeeds and Corms64-86-8HighA clinically approved tubulin-binding anti-inflammatory used medically for acute gout attacks and familial Mediterranean fever management.
QUINAZOLINE & OTHER ALKALOIDS
GalegineIsoamylene guanidine; Metformin precursorAlkaloid (Guanidine)Goat's RueGalega officinalisAerial Parts543-19-5ModerateThe botanical compound that inspired the development of metformin; studied for glucose-lowering effects via cellular glucose uptake enhancement.
VasicinoneAdhatoda quinazoline alkaloidAlkaloid (Quinazoline)Malabar NutAdhatoda vasicaLeaves486-64-6ModerateStudied for bronchodilatory and mucolytic properties; supports the traditional and clinical use of Adhatoda for respiratory conditions.
DeoxyvasicinoneVasicinone analog; Adhatoda alkaloidAlkaloid (Quinazoline)Malabar NutAdhatoda vasicaLeavesModerateStudied for synergistic bronchodilatory and mucus-clearing properties alongside vasicinone in respiratory health preparations.
PilocarpineJaborandi alkaloid; Imidazole alkaloidAlkaloid (Imidazole)JaborandiPilocarpus jaborandiLeaves92-13-7HighA clinically established parasympathomimetic used medically for glaucoma management (reducing intraocular pressure) and xerostomia.
IsopilocarpinePilocarpine isomer; JaborandiAlkaloid (Imidazole)JaborandiPilocarpus jaborandiLeaves492-72-8EmergingA structural isomer of pilocarpine with weaker parasympathetic stimulation; separated during pharmaceutical purification of pilocarpine.
IsopilosineJaborandi minor alkaloidAlkaloid (Imidazole)JaborandiPilocarpus jaborandiLeavesEmergingA minor alkaloid from Jaborandi with mild ophthalmic activity; typically removed during pharmaceutical-grade pilocarpine production.
LigustrazineTetramethylpyrazine; TMP; Ligusticum alkaloidAlkaloid (Pyrazine)ChuanxiongLigusticum chuanxiongRhizome1124-11-4ModerateStudied for vasodilatory and antiplatelet effects that may support cerebral and cardiovascular blood flow; used clinically in China as an injectable.
KifunensineGlycosidase research toolAlkaloid (Indolizidine)ActinobacteriumKitasatospora kifunensisCellular Matrix109001-77-6EmergingA highly selective alpha-mannosidase I inhibitor used strictly in laboratory research to study glycoprotein processing and N-glycan remodelling.
SlaframineBlack Patch Fungus salivogenAlkaloid (Indolizidine)Black Patch FungusRhizoctonia leguminicolaFungal Cells15973-24-3EmergingA parasympathomimetic mycotoxin that causes excessive salivation in livestock via overstimulation of muscarinic receptors; of agricultural and toxicological research interest.
Capsaicin8-Methyl-N-vanillyl-6-nonenamide; VanilloidAlkaloid (Pseudoalkaloid)Chili PepperCapsicum annuumFruit and Seeds404-86-4HighA TRPV1 receptor agonist with well-documented topical analgesic applications; supported by clinical evidence for localised pain management in neuropathy and musculoskeletal conditions.
ErgocristineErgot alkaloid; VasoconstrictorAlkaloid (Indole)Ergot FungusClaviceps purpureaSclerotium511-08-0ModerateAn ergopeptine vasoconstrictor studied for uterine and vascular smooth muscle effects; part of the pharmacologically complex ergot alkaloid family.
ErgocryptineErgot alkaloid; DopaminergicAlkaloid (Indole)Ergot FungusClaviceps purpureaSclerotium561-78-4ModerateStudied for dopamine receptor interactions; forms the biological basis for the development of dopaminergic drugs used in Parkinson's disease management.
ErgosineErgot toxic alkaloidAlkaloid (Indole)Ergot FungusClaviceps purpureaSclerotium561-94-4ModerateAn ergot alkaloid associated with peripheral vasoconstriction; part of the toxic alkaloid complex responsible for ergotism. Documented for safety reference.
ErgocornineErgot alkaloid; Migraine researchAlkaloid (Indole)Ergot FungusClaviceps purpureaSclerotium564-36-3ModerateAn ergopeptine that causes potent peripheral vasoconstriction; studied in the context of migraine management research.
ErgonovineErgobasine; Ergometrine; Obstetric ergotAlkaloid (Indole)Ergot FungusClaviceps purpureaSclerotium60-79-7HighA clinically used uterotonic that selectively contracts uterine smooth muscle; used medically to prevent and treat postpartum haemorrhage under clinical supervision.
ErgotaminineErgotamine isomer; Inactive ergotAlkaloid (Indole)Ergot FungusClaviceps purpureaSclerotium639-81-6EmergingThe biologically inactive epimer of ergotamine; used as an analytical reference marker during pharmaceutical isolation of active ergot alkaloids.
FLAVONOLS
Quercetin3,3',4',5,7-Pentahydroxyflavone; SophoretinPolyphenol (Flavonol)Red OnionAllium cepaOuter Bulb Scales117-39-5ModerateA widely studied dietary flavonol; may support normal antioxidant defence and healthy inflammatory balance. Some evidence for mast cell stabilisation relevant to seasonal allergies.
Kaempferol3,4',5,7-TetrahydroxyflavonePolyphenol (Flavonol)BroccoliBrassica oleraceaFlorets520-18-3ModerateStudied for anti-inflammatory and antioxidant properties; may contribute to cardiovascular protection and healthy cell cycle regulation when consumed in plant-rich diets.
Fisetin3,3',4',7-Tetrahydroxyflavone; FisteinPolyphenol (Flavonol)StrawberryFragaria ananassaFruit528-48-3ModerateStudied for senolytic properties and potential to support healthy aging by reducing accumulation of senescent cells; promising preclinical data with limited human trials.
Myricetin3,3',4',5,5',7-HexahydroxyflavonePolyphenol (Flavonol)Goji BerryLycium barbarumDried Fruit529-44-2ModerateStudied for antioxidant, anti-inflammatory, and potential neuroprotective properties; associated with healthy blood glucose management in preclinical models.
Isorhamnetin3'-Methoxy-3,4',5,7-tetrahydroxyflavone; Quercetin-3'-methyl etherPolyphenol (Flavonol)GinkgoGinkgo bilobaLeaves480-19-3ModerateA methylated quercetin metabolite studied for potential neuroprotective and anti-inflammatory properties; of interest in cardiovascular and cognitive health research.
Morin2',3,4',5,7-PentahydroxyflavonePolyphenol (Flavonol)GuavaPsidium guajavaFruit480-16-0ModerateStudied for antioxidant and potential neuroprotective effects; may support immune function and inhibit uric acid synthesis, with relevance to gout management research.
Galangin3,5,7-Trihydroxyflavone; Galangin flavonolPolyphenol (Flavonol)GalangalAlpinia officinarumRhizome548-83-4ModerateStudied for antiviral, antibacterial, and anti-inflammatory properties; may modulate eicosanoid pathways relevant to the body's healthy inflammatory response.
RutinQuercetin-3-rutinoside; Rutoside; Vitamin PPolyphenol (Flavonol Glycoside)BuckwheatFagopyrum esculentumAerial Parts153-18-4ModerateThe glycosylated form of quercetin; studied for capillary-strengthening and anti-oedematous properties. Used clinically in some countries for venous insufficiency support.
Gossypetin8-Hydroxyquercetin; Hibiscus flavonolPolyphenol (Flavonol)HibiscusHibiscus sabdariffaCalyx489-35-0ModerateStudied for diuretic and antihypertensive properties; a distinctive 8-hydroxylated flavonol found in hibiscus calyx preparations.
Quercetagetin6-Hydroxyquercetin; Marigold flavonolPolyphenol (Flavonol)MarigoldTagetes erectaFlower Petals1169-23-9EmergingA hexahydroxylated flavonol studied for antiviral and antiproliferative properties in early-stage laboratory research.
Patuletin6-Methoxyquercetin; Marigold flavonolPolyphenol (Flavonol)MarigoldTagetes patulaFlower Petals20229-30-5EmergingStudied for anti-inflammatory and chondroprotective properties in early-stage research; may contribute to joint health maintenance.
Spinacetin5,3'-Dihydroxy-3,4',7-trimethoxyflavonePolyphenol (Flavonol)SpinachSpinacia oleraceaLeaves28610-81-3EmergingA methylated flavonol found in spinach; studied for antioxidant activity in early-stage research.
Isorhamnetin-3-glucosideIsorhamnetin glucoside; NarcissinPolyphenol (Flavonol Glycoside)Sea BuckthornHippophae rhamnoidesBerries5041-82-7ModerateA bioavailable isorhamnetin glycoside studied for cardiovascular and anti-inflammatory properties in the context of sea buckthorn berry consumption.
Laricitrin3,4',5,7-Tetrahydroxy-3'-methoxyflavonolPolyphenol (Flavonol)Red Wine GrapeVitis viniferaFruit Skin16290-07-6EmergingA minor grape skin flavonol studied for antioxidant and vascular health-supporting properties.
Syringetin3,4',5,7-Tetrahydroxy-3',5'-dimethoxyflavonolPolyphenol (Flavonol)Red Wine GrapeVitis viniferaFruit Skin528-53-0EmergingA methylated flavonol found in grape skin; studied for potential contributions to cardiovascular antioxidant protection.
FLAVONES
Apigenin4',5,7-Trihydroxyflavone; Chamomile FlavonePolyphenol (Flavone)ParsleyPetroselinum crispumLeaf / Stalk520-36-5ModerateStudied for mild anxiolytic, anti-inflammatory, and potential neuroprotective properties; may support healthy nervous system function and cellular autophagy.
Luteolin3',4',5,7-TetrahydroxyflavonePolyphenol (Flavone)CeleryApium graveolensLeaf / Seed491-70-3ModerateStudied for anti-inflammatory and potential neuroprotective properties; may contribute to mast cell stabilisation and support a healthy inflammatory balance.
DiosminDiovenor; Detralex constituentPolyphenol (Flavone Glycoside)Sweet OrangeCitrus sinensisFruit Peel520-27-4HighA clinically used phlebotonic flavonoid; well-supported by RCTs for venous insufficiency and haemorrhoidal symptom management, typically combined with hesperidin.
DiosmetinDiosmin aglycone; 4'-Methyl-luteolinPolyphenol (Flavone)Lemon / CitrusCitrus limonFruit Peel520-34-3ModerateThe aglycone of diosmin; studied for venous tone support and anti-inflammatory properties relevant to circulatory health.
Acacetin4'-Methoxy-apigenin; Black Locust flavonePolyphenol (Flavone)Black LocustRobinia pseudoacaciaFlowers480-44-4ModerateStudied for antiarrhythmic and anti-inflammatory properties; may contribute to the stabilisation of cardiac electrical activity in preclinical models.
Tangeretin4',5,6,7,8-Pentamethoxyflavone; Citrus flavonePolyphenol (Flavone)TangerineCitrus reticulataFruit Peel481-53-8ModerateA polymethoxylated flavone studied for neuroprotective and potential antiproliferative properties; may cross the blood-brain barrier more readily than less methylated flavones.
Nobiletin3',4',5,6,7,8-HexamethoxyflavonePolyphenol (Flavone)TangerineCitrus reticulataFruit Peel478-01-3ModerateStudied for circadian rhythm modulation, hepatic lipid regulation, and potential neuroprotective properties; of interest in metabolic syndrome and dementia research.
Sinensetin3',4',5,6,7-PentamethoxyflavonePolyphenol (Flavone)Sweet OrangeCitrus sinensisFruit Peel466-49-9EmergingA polymethoxylated citrus flavone studied for anti-angiogenic and anti-inflammatory properties in early-stage laboratory research.
Baicalein5,6,7-Trihydroxyflavone; Scutellaria aglyconePolyphenol (Flavone)Chinese SkullcapScutellaria baicalensisRoots491-67-8ModerateStudied for antiviral, anti-inflammatory, and potential neuroprotective properties; the aglycone of baicalin with higher membrane permeability.
BaicalinBaicalein-7-glucuronide; Scutellaria glycosidePolyphenol (Flavone Glycoside)Chinese SkullcapScutellaria baicalensisRoots21967-41-9ModerateThe primary flavone of Scutellaria root; studied for anxiolytic, anti-inflammatory, and antiviral properties, with some human trial data available.
Wogonin5,7-Dihydroxy-8-methoxyflavonePolyphenol (Flavone)Chinese SkullcapScutellaria baicalensisRoots632-85-9ModerateStudied for neuroprotective, anti-inflammatory, and potential anti-anxiety properties in preclinical models; complements baicalin in Scutellaria preparations.
Scutellarein6-Hydroxy-4',5,7-trihydroxyflavonePolyphenol (Flavone)Chinese SkullcapScutellaria baicalensisRoots529-53-3EmergingStudied for potential antiviral and neuroprotective effects in early-stage research; a hydroxylated flavone that may contribute to Scutellaria's anti-infective properties.
Hispidulin4'-Methoxy-5,6,7-trihydroxyflavone; DinatinPolyphenol (Flavone)SageSalvia officinalisLeaves1447-88-7EmergingStudied for GABA-A receptor modulation with potential anticonvulsant properties in preclinical models; may support healthy nervous system calming.
Eupatilin5,7-Dihydroxy-3',4',6-trimethoxyflavonePolyphenol (Flavone)MugwortArtemisia asiaticaLeaves22368-21-4ModerateA methylated flavone studied for gastroprotective properties; clinically investigated in South Korea for gastric mucosa protection and ulcer support.
Vitexin8-C-Glucosylapigenin; Hawthorn flavonePolyphenol (Flavone C-Glycoside)HawthornCrataegus spp.Fruit / Leaf3681-93-4ModerateStudied for cardioprotective, antihypertensive, and antispasmodic properties; contributes to the well-established cardiovascular benefit of hawthorn preparations.
Isovitexin6-C-Glucosylapigenin; Passion Flower flavonePolyphenol (Flavone C-Glycoside)Passion FlowerPassiflora incarnataAerial Parts38953-85-4ModerateStudied for anxiolytic and sedative-supportive properties; contributes to the evidence base for passionflower in sleep quality support.
Orientin8-C-Glucosylluteolin; Rooibos flavonePolyphenol (Flavone C-Glycoside)RooibosAspalathus linearisLeaves28543-07-9ModerateStudied for antioxidant, cardioprotective, and anti-inflammatory properties; a characteristic flavone of rooibos tea with good bioavailability data.
Iso-orientin6-C-Glucosylluteolin; Barley grass flavonePolyphenol (Flavone C-Glycoside)Barley GrassHordeum vulgareYoung Leaves4261-42-1ModerateStudied for antioxidant and hepatoprotective properties; contributes to the nutritional profile of barley grass preparations.
RhoifolinApigenin-7-neohesperidosidePolyphenol (Flavone Glycoside)Sour OrangeCitrus aurantiumFruit Peel17306-46-6ModerateStudied for cardioprotective and lipid-modulating properties; contributes to the overall flavonoid profile of bitter citrus preparations.
Vicenin-26,8-Di-C-glucosylapigenin; Tulsi flavonePolyphenol (Flavone C-Glycoside)Tulsi (Holy Basil)Ocimum sanctumLeaves4604-81-3ModerateStudied for radioprotective and immunomodulatory properties in preclinical research; contributes to the adaptogenic profile of holy basil.
Chrysin5,7-Dihydroxyflavone; Bee Propolis flavonePolyphenol (Flavone)Bee PropolisPopulus spp.Resin480-40-0ModerateStudied for potential aromatase-inhibiting properties and mild anxiolytic effects; human bioavailability is poor without delivery enhancement.
Geraldone3',5'-Dimethoxy-4'-hydroxyflavone; Red Clover flavonePolyphenol (Flavone)Red CloverTrifolium pratenseFlowers480-44-4EmergingA minor flavone studied for oestrogenic and bone density-supporting properties in the context of red clover isoflavone research.
FLAVANONES
HesperidinHesperetin-7-rutinoside; Diosmin companionPolyphenol (Flavanone Glycoside)Sweet OrangeCitrus sinensisFruit Peel520-26-3ModerateStudied for venous tone support, capillary permeability reduction, and anti-inflammatory properties; used in combination with diosmin in clinically validated venous products.
Naringenin4',5,7-Trihydroxyflavanone; Citrus aglyconePolyphenol (Flavanone)GrapefruitCitrus paradisiFruit Peel480-41-1ModerateStudied for insulin-sensitising, hepatoprotective, and anti-inflammatory properties; may support healthy metabolic balance when consumed as part of a citrus-rich diet.
NaringinNaringenin-7-neohesperidosidePolyphenol (Flavanone Glycoside)GrapefruitCitrus paradisiFruit Peel10236-47-2ModerateStudied for CYP3A4 inhibition that can significantly increase bioavailability of co-administered compounds; also studied for lipid-lowering and bone health-supporting properties.
Hesperetin4'-Methoxy-eriodictyol; Hesperidin aglyconePolyphenol (Flavanone)LemonCitrus limonFruit Peel520-33-2ModerateThe bioactive aglycone of hesperidin; studied for vasotonic, anti-inflammatory, and potential neuroprotective effects with good intestinal permeability.
Eriodictyol3',4',5,7-Tetrahydroxyflavanone; Yerba SantaPolyphenol (Flavanone)Yerba SantaEriodictyon californicumLeaves552-58-9ModerateStudied for mucolytic, anti-inflammatory, and flavour-modifying properties; investigated as a bitterness-masking agent in food and pharmaceutical formulations.
PoncirinIsosakuranetin-7-neohesperidosidePolyphenol (Flavanone Glycoside)Trifoliate OrangePoncirus trifoliataUnripe Fruit14941-08-3ModerateStudied for gastroprotective effects against ulceration and for apoptosis-inducing properties in cancer cell line research.
DidyminIsosakuranetin-7-rutinoside; Mandarin flavanonePolyphenol (Flavanone Glycoside)Mandarin OrangeCitrus reticulataFruit Peel14259-45-1EmergingStudied for neuroprotective properties and potential to stimulate nerve growth factor expression in preclinical models.
Sakuranetin5,4'-Dihydroxy-7-methoxyflavanone; Rice phytoalexinPolyphenol (Flavanone)Rice / Cherry TreeOryza sativaLeaves1486-69-7ModerateA phytoalexin produced by rice in response to fungal infection; studied for antiallergic and anti-inflammatory properties in human cell models.
SterubinEriodictyol-7-methyl etherPolyphenol (Flavanone)Yerba SantaEriodictyon californicumLeaves3145-22-4EmergingStudied in early-stage research for potential neuroprotective effects on ageing neurons; of interest in Alzheimer's disease pharmacological research.
BavachinPsoralea flavanone; Bakuchiol companionPolyphenol (Flavanone)PsoraleaPsoralea corylifoliaSeeds20784-50-3ModerateStudied for osteogenic and anti-inflammatory properties; contributes to the bone health-supportive and immune-modulatory profile of Psoralea preparations.
LiquiritinLicorice flavanone; Liquiritigenin glucosidePolyphenol (Flavanone Glycoside)Licorice RootGlycyrrhiza glabraRoots551-15-5ModerateStudied for gastroprotective and antidepressant-like properties; contributes to the well-established digestive-soothing benefits of licorice root preparations.
FLAVAN-3-OLS (CATECHINS & PROANTHOCYANIDINS)
Catechin(+)-Catechin; Catechinic acidPolyphenol (Flavan-3-ol)Green TeaCamellia sinensisLeaves154-23-4ModerateA dietary flavan-3-ol studied for antioxidant and cardiovascular-supportive properties; may contribute to healthy vascular function and normal lipid profiles.
Epicatechin(-)-Epicatechin; ECPolyphenol (Flavan-3-ol)Dark ChocolateTheobroma cacaoSeeds (Bean)490-46-0ModerateStudied for vasodilatory, cardioprotective, and potential muscle function-supporting properties; associated with improved endothelial function in clinical trials at high cocoa intake.
EGCGEpigallocatechin gallate; EGCg; Tea CatechinPolyphenol (Flavan-3-ol)Green TeaCamellia sinensisLeaves989-51-5ModerateThe most studied green tea catechin; may support metabolic health, immune function, and antioxidant defence. Human bioavailability is moderate and effect sizes vary across trials.
Epicatechin GallateECG; (-)-Epicatechin-3-gallatePolyphenol (Flavan-3-ol)Green TeaCamellia sinensisLeaves1257-08-5ModerateA green tea catechin gallate ester; studied for antimicrobial and antioxidant properties alongside EGCG in the context of green tea's overall health benefits.
Gallocatechin(+)-Gallocatechin; GCPolyphenol (Flavan-3-ol)Green TeaCamellia sinensisLeaves3371-27-5ModerateA flavan-3-ol present in green tea alongside EGCG; contributes to the cumulative antioxidant and anti-inflammatory activity of tea catechin mixtures.
Gallocatechin GallateGCG; (+)-Gallocatechin-3-gallatePolyphenol (Flavan-3-ol)Green TeaCamellia sinensisLeaves4233-96-9ModerateStudied for lipid metabolism-modulating and immunomodulatory properties as part of the green tea catechin complex.
ProcyanidinsOPC; Oligomeric proanthocyanidins; PACPolyphenol (Proanthocyanidin)Grape Seed / AppleVitis vinifera / Malus domesticaSeeds / SkinModerateA class of condensed tannins studied extensively for cardiovascular, skin, and antioxidant support; grape seed extract OPCs have multiple human trials showing bioavailability and vascular benefits.
Procyanidin B2Epicatechin-(4b-8)-epicatechinPolyphenol (Proanthocyanidin)CocoaTheobroma cacaoSeeds29106-49-8ModerateStudied for vasodilatory, skin elasticity-supporting, and antioxidant properties; one of the best-characterised proanthocyanidin dimers.
Procyanidin C1Epicatechin trimerPolyphenol (Proanthocyanidin)Grape SeedVitis viniferaSeeds37064-30-5EmergingStudied in early-stage research for potential senolytic properties; of interest in longevity and healthy aging research.
TheaflavinTF1; Black Tea polyphenolPolyphenol (Theaflavin)Black TeaCamellia sinensisFermented Leaves4670-05-7ModerateThe characteristic orange-red pigment of black tea; studied for cholesterol-lowering and cardiovascular-supportive properties with promising clinical trial data.
ThearubiginsTR; Black Tea polymersPolyphenol (Theaflavin)Black TeaCamellia sinensisFermented LeavesModerateA complex mixture of oxidised catechin polymers accounting for most of black tea's colour and antioxidant capacity; studied for gut health and cardiovascular support.
FLAVANONOLS (DIHYDROFLAVONOLS)
TaxifolinDihydroquercetin; DHQ; Siberian Larch extractPolyphenol (Flavanonol)Siberian LarchLarix sibiricaWood / Bark480-18-2ModerateStudied for antioxidant, capillary-strengthening, and hepatoprotective properties; used in supplements for vascular and liver health with some human trial data.
AromadendrinDihydrokaempferol; Eucalyptus flavanonolPolyphenol (Flavanonol)EucalyptusEucalyptus globulusWood / Leaves480-20-6ModerateStudied for antioxidant and mild blood glucose-modulating properties; a biosynthetic intermediate in the flavonoid pathway.
AmpelopsinDihydromyricetin; DHM; Vine TeaPolyphenol (Flavanonol)Vine TeaAmpelopsis grossedentataLeaves27200-12-0ModerateStudied for hepatoprotective properties and support for alcohol metabolism; may accelerate ethanol clearance. Chinese clinical research available though quality is variable.
FLAVONOLIGNANS
SilybinSilibinin; Milk Thistle primary flavonolignanPolyphenol (Flavonolignan)Milk ThistleSilybum marianumSeeds22888-70-6HighThe primary bioactive of Milk Thistle (Silymarin complex); well-supported by clinical trials for hepatoprotective effects; may support liver cell membrane integrity against toxins.
SilychristinSilymarin component BPolyphenol (Flavonolignan)Milk ThistleSilybum marianumSeeds33889-69-9ModerateA constituent of the silymarin complex studied for hepatoprotective and antioxidant effects; may contribute to liver tissue regeneration alongside silybin.
SilydianinSilymarin component CPolyphenol (Flavonolignan)Milk ThistleSilybum marianumSeeds29782-68-1ModerateA minor silymarin component studied for stimulation of RNA polymerase I activity, which may support hepatocyte regeneration.
ISOFLAVONES & PHYTOESTROGENS
Genistein5,7,4'-Trihydroxyisoflavone; Soy isoflavonePolyphenol (Isoflavone)SoybeanGlycine maxMature Seed446-72-0ModerateA phytoestrogenic isoflavone studied for potential benefits to bone density and menopausal symptoms; bioactivity is context-dependent and varies with individual gut microbiome composition.
Daidzein7,4'-Dihydroxyisoflavone; Soy isoflavonePolyphenol (Isoflavone)SoybeanGlycine maxMature Seed486-66-8ModerateA phytoestrogenic isoflavone studied for cardiovascular and antioxidant properties; its conversion to equol in the gut is a key variable determining individual response.
Biochanin A4'-Methylgenistein; Red Clover isoflavonePolyphenol (Isoflavone)Red CloverTrifolium pratenseFlower Heads491-80-5ModerateA methylated isoflavone that is demethylated to genistein in vivo; studied for hormonal balance support and potential contributions to muscle strength maintenance.
Formononetin7-Hydroxy-4'-methoxyisoflavone; Red CloverPolyphenol (Isoflavone)Red CloverTrifolium pratenseAerial Parts485-72-3ModerateA phytoestrogenic isoflavone studied for bone density support and female hormonal health; converted to daidzein and equol in the human gut.
Glycitein6-Methoxydaidzein; Soy minor isoflavonePolyphenol (Isoflavone)SoybeanGlycine maxMature Seed40957-83-3ModerateA minor soy isoflavone studied for oestrogenic and antioxidant properties; contributes to the overall health profile of soy-based foods and isoflavone extracts.
DaidzinDaidzein-7-glucoside; Soy isoflavone glycosidePolyphenol (Isoflavone Glycoside)Kudzu RootPueraria lobataRoots552-66-9ModerateStudied for potential to reduce alcohol craving and support cardiovascular health; the glucoside form of daidzein with distinct pharmacokinetic properties.
PuerarinDaidzein-8-C-glucoside; Kudzu root isoflavonePolyphenol (Isoflavone C-Glycoside)KudzuPueraria lobataRoots3681-99-0ModerateStudied for cardiovascular benefits including improved cerebral blood flow and potential reduction of alcohol-seeking behaviour; used clinically in China.
Calycosin3'-Hydroxyformononetin; Astragalus isoflavonePolyphenol (Isoflavone)AstragalusAstragalus membranaceusRoots20575-57-9ModerateStudied for potential pro-angiogenic and oestrogen receptor-mediated effects; contributes to the cardiovascular and adaptogenic activity of Astragalus root.
IrisolidonePratensein; Pueraria isoflavonePolyphenol (Isoflavone)Kudzu / IrisPueraria lobataRoots32752-26-4EmergingA methylated isoflavone studied for antioxidant and potential immunomodulatory properties in early-stage research.
Equol(S)-Equol; Gut microbiome metabolitePolyphenol (Isoflavandiol)Human MicrobiomeDerived from SoyIntestinal By-product531-95-3ModerateA gut bacterial metabolite of daidzein with higher oestrogenic potency than its parent; associated with more pronounced isoflavone health benefits in equol-producer individuals.
GlabridinLicorice isoflavan; Skin-brightening agentPolyphenol (Isoflavan)Licorice RootGlycyrrhiza glabraRoots59870-68-7ModerateStudied for tyrosinase inhibition, UV protection, and anti-inflammatory properties; widely used in dermatological preparations for skin-brightening support.
Prunetin5-Methylgenistein; Plum isoflavonePolyphenol (Isoflavone)PlumPrunus domesticaWood / Bark552-59-0EmergingA methylated isoflavone studied for anti-inflammatory and cardiovascular protective properties in early-stage research.
CoumestrolCoumestan phytoestrogen; AlfalfaPolyphenol (Coumestan)AlfalfaMedicago sativaLeaves / Sprouts479-13-0ModerateThe most potent plant coumestan phytoestrogen; studied for oestrogenic receptor activity relevant to bone density, menopausal health, and hormonal balance research.
WedelolactoneEclipta coumestan; Liver protectorPolyphenol (Coumestan)False DaisyEclipta prostrataAerial Parts524-12-9ModerateStudied for hepatoprotective, anti-venom, and anti-inflammatory properties; supports the traditional use of Eclipta in Ayurvedic medicine for liver health.
PsoralidinPsoralea coumestanPolyphenol (Coumestan)Scurfy PeaPsoralea corylifoliaSeeds19879-32-4EmergingStudied for antimicrobial and antiproliferative properties in early-stage laboratory research; contributes to the pharmacological activity of Psoralea seed preparations.
CHALCONES & DIHYDROCHALCONES
Isoliquiritigenin4,4',2'-Trihydroxychalcone; Licorice chalconePolyphenol (Chalcone)Licorice RootGlycyrrhiza glabraRoots961-29-5ModerateStudied for smooth muscle relaxant, anti-inflammatory, and potential oestrogenic properties; contributes to the digestive-soothing activity of licorice root.
Butein3,4,2',4'-TetrahydroxychalconePolyphenol (Chalcone)ToxicodendronToxicodendron vernicifluumHeartwood487-52-5ModerateStudied for potent anti-inflammatory and antioxidant properties; may support inhibition of NF-kB and STAT3 pathways relevant to chronic inflammation.
Phloretin2',4,4',6'-Tetrahydroxychalcone; Apple chalconePolyphenol (Dihydrochalcone)AppleMalus domesticaLeaves / Bark60-82-2ModerateStudied for antioxidant, anti-inflammatory, and potential insulin-sensitising properties; inhibits glucose transport across cell membranes in laboratory models.
PhloridzinPhloretin-2'-glucoside; Apple bark glycosidePolyphenol (Dihydrochalcone)AppleMalus domesticaBark / Root Bark60-81-1ModerateStudied for SGLT inhibition and blood glucose-lowering effects; formed the conceptual basis for the SGLT2 inhibitor drug class used clinically in diabetes management.
AspalathinRooibos dihydrochalcone; C-glucosidePolyphenol (Dihydrochalcone)RooibosAspalathus linearisLeaves88597-18-6ModerateA unique South African plant polyphenol; studied for antidiabetic, cardioprotective, and oxidative stress-reducing properties with a moderate evidence base.
Naringenin ChalconeNaringenin open-form; Tomato chalconePolyphenol (Chalcone)TomatoSolanum lycopersicumSkinEmergingThe chalcone biosynthetic precursor of naringenin; studied for anti-inflammatory properties and found naturally in tomato skin.
PRENYLFLAVONOIDS
XanthohumolXN; Hops prenylflavonoidPolyphenol (Prenylflavonoid)HopsHumulus lupulusFemale Inflorescence6754-58-1ModerateStudied for broad-spectrum anti-inflammatory, antioxidant, and potential cancer chemopreventive properties; the most abundant prenylflavonoid in hops.
IsoxanthohumolIXN; Hops prenylflavanonePolyphenol (Prenylflavonoid)HopsHumulus lupulusFemale Inflorescence70553-76-3ModerateStudied as a mild phytoestrogen and for its conversion to the more potent 8-prenylnaringenin; contributes to the hormonal balance-supporting profile of hops.
8-Prenylnaringenin8-PN; Hops potent phytoestrogenPolyphenol (Prenylflavonoid)HopsHumulus lupulusFemale Inflorescence53846-50-7ModerateConsidered among the most potent plant phytoestrogens; studied for menopausal symptom management including hot flush relief. Limited but emerging clinical evidence.
ANTHOCYANINS & ANTHOCYANIDINS
CyanidinCyanidin chloride; Red-blue anthocyanidinPolyphenol (Anthocyanidin)BlackberryRubus fruticosusFruit Skin528-58-5ModerateStudied for vascular protection, antioxidant activity, and potential blood glucose-modulating properties; widely distributed in dark-coloured berries and fruits.
DelphinidinBlue-purple anthocyanidinPolyphenol (Anthocyanidin)BlueberryVaccinium corymbosumFruit Skin528-53-0ModerateStudied for antioxidant, anti-inflammatory, and potential cardioprotective properties; associated with healthy cognitive aging in epidemiological research.
MalvidinRed wine anthocyanidin; 3',5'-Dimethoxy-delphinidinPolyphenol (Anthocyanidin)Red Wine GrapeVitis viniferaFruit Skin643-84-5ModerateThe predominant anthocyanidin in red wine; studied for cardiovascular protection including arterial flexibility support and platelet aggregation modulation.
Peonidin3'-Methoxy-cyanidin; Cranberry anthocyanidinPolyphenol (Anthocyanidin)CranberryVaccinium oxycoccosFruit Skin134-01-0ModerateStudied for antioxidant and anti-inflammatory properties; contributes to the urinary tract health-supportive profile of cranberry alongside proanthocyanidins.
PelargonidinOrange-red anthocyanidin; Strawberry pigmentPolyphenol (Anthocyanidin)StrawberryFragaria ananassaFruit Skin134-04-3ModerateA dietary anthocyanidin studied for anti-inflammatory and vascular health-supportive properties; the primary pigment of strawberries.
PetunidinBlue-purple anthocyanidin; Black CurrantPolyphenol (Anthocyanidin)Black CurrantRibes nigrumFruit Skin1429-30-7ModerateStudied for antioxidant and anti-inflammatory properties; contributes to the cardiovascular and cognitive health support associated with dark berry consumption.
Cyanidin-3-glucosideC3G; Kuromanin; Berry anthocyaninPolyphenol (Anthocyanin)ElderberrySambucus nigraFruit7084-24-4ModerateA highly bioavailable anthocyanin form; studied for antioxidant, anti-inflammatory, and potential antiviral properties with some human bioavailability data.
Cyanidin-3-rutinosideKeracyanin; Tart Cherry anthocyaninPolyphenol (Anthocyanin)Tart CherryPrunus cerasusFruit Skin28338-59-2ModerateStudied for anti-inflammatory and muscle recovery support; human trials support its role in reducing exercise-induced muscle soreness.
Delphinidin-3-glucosideMyrtillin; Bilberry anthocyaninPolyphenol (Anthocyanin)BilberryVaccinium myrtillusFruit Skin6906-38-3ModerateStudied for retinal protection and visual acuity support; bilberry anthocyanins have an established evidence base for eye health, particularly in low-light adaptation.
STILBENES
ResveratrolTrans-resveratrol; 3,5,4'-TrihydroxystilbenePolyphenol (Stilbene)Red GrapesVitis viniferaFruit Skin501-36-0ModerateA polyphenolic stilbene studied for sirtuin activation, cardiovascular protection, and anti-aging properties; human bioavailability is limited and effect sizes in trials are modest.
Pterostilbene3,5-Dimethoxy-4'-hydroxystilbene; Blueberry stilbenePolyphenol (Stilbene)BlueberryVaccinium corymbosumFruit537-42-8ModerateA dimethylated resveratrol analog with significantly improved oral bioavailability; studied for cognitive support, antioxidant, and potential lipid-lowering properties.
Piceatannol3,3',4,5'-Tetrahydroxystilbene; Passion Fruit stilbenePolyphenol (Stilbene)Passion FruitPassiflora edulisSeeds10083-24-6ModerateA hydroxylated resveratrol metabolite with higher potency; studied for anti-inflammatory, antiproliferative, and potential skin health-supporting properties.
Pinostilbene3,4'-Dihydroxy-5-methoxystilbenePolyphenol (Stilbene)Siberian PinePinus sibiricaBark22139-77-1EmergingA monomethylated resveratrol analog studied for antioxidant and anti-inflammatory properties in early-stage research.
RhaponticinRhapontin; Rhubarb stilbene glucosidePolyphenol (Stilbene Glycoside)RhubarbRheum rhabarbarumRhizome155-58-8ModerateA stilbene glycoside studied for oestrogenic receptor binding and potential support for menopausal symptoms; contributes to the phytoestrogenic activity of rhubarb root.
PHENOLIC ACIDS — HYDROXYCINNAMIC
Chlorogenic Acid3-Caffeoylquinic acid; CGA; Green CoffeePolyphenol (Hydroxycinnamic Acid)Green CoffeeCoffea arabicaDried Seed327-97-9ModerateStudied for blood glucose-modulating properties by slowing carbohydrate absorption; well-documented antioxidant with moderate human trial evidence.
Caffeic Acid3,4-Dihydroxycinnamic acidPolyphenol (Hydroxycinnamic Acid)CoffeeCoffea arabicaSeed (Bean)331-39-5ModerateStudied for antioxidant and anti-inflammatory properties; may help inhibit formation of advanced glycation end-products relevant to metabolic health.
Rosmarinic Acidalpha-O-Caffeoyl-3,4-dihydroxyphenyllactic acidPolyphenol (Hydroxycinnamic Acid)RosemarySalvia rosmarinusLeaf Tissue20283-92-5ModerateStudied for antioxidant, anti-inflammatory, and potential anxiolytic properties; supports the traditional use of rosemary and lemon balm for cognitive and mood wellbeing.
Ferulic Acid3-Methoxy-4-hydroxycinnamic acid; FAPolyphenol (Hydroxycinnamic Acid)Whole WheatTriticum aestivumCereal Bran1135-24-6ModerateStudied for neuroprotective, antioxidant, and skin-photoprotective properties; may support healthy endothelial function and contribute to the value of whole grain consumption.
Sinapic Acid3,5-Dimethoxy-4-hydroxycinnamic acidPolyphenol (Hydroxycinnamic Acid)Mustard GreensBrassica junceaLeaves530-59-6ModerateStudied for antioxidant and anti-inflammatory properties; may support neuroprotection and serve as a skin UV-filter in topical applications.
p-Coumaric Acid4-Hydroxycinnamic acid; Para-coumaric acidPolyphenol (Hydroxycinnamic Acid)PeanutsArachis hypogaeaSeeds501-98-4ModerateStudied for antioxidant and potential anti-atherosclerotic properties; may help maintain healthy lipid profiles when consumed as part of a plant-rich diet.
Cinnamic Acid(E)-3-Phenylacrylic acid; Trans-cinnamic acidPolyphenol (Hydroxycinnamic Acid)CinnamonCinnamomum cassiaBark140-10-3ModerateStudied for antimicrobial and antioxidant properties; a primary aromatic constituent of cinnamon with mild anti-inflammatory activity.
Chicoric AcidCichoric acid; Echinacea phenolicPolyphenol (Hydroxycinnamic Acid)EchinaceaEchinacea purpureaRoots / Leaves70831-56-0ModerateStudied for immunomodulatory effects including enhancement of phagocytic activity; contributes to the immune-supportive evidence base of Echinacea preparations.
Caftaric AcidCaffeoyl tartaric acid; Grapevine phenolicPolyphenol (Hydroxycinnamic Acid)GrapevineVitis viniferaFruit / Juice67879-58-7ModerateA hydroxycinnamic acid ester found in grapes and wine; studied for antioxidant and potential antiviral properties.
PHENOLIC ACIDS — HYDROXYBENZOIC
Gallic Acid3,4,5-Trihydroxybenzoic acidPolyphenol (Hydroxybenzoic Acid)Tea PlantCamellia sinensisLeaves149-91-7ModerateStudied for antioxidant, antimicrobial, and hepatoprotective properties; a key building block of hydrolysable tannins and an important dietary antioxidant.
Ellagic AcidBenzoaric acid; Pomegranate polyphenolPolyphenol (Hydroxybenzoic Acid)PomegranatePunica granatumFruit / Seed Husk476-66-4ModerateStudied for antiproliferative and antioxidant properties; released from ellagitannins in the gut and studied for potential support of healthy cell cycle regulation.
Protocatechuic Acid3,4-Dihydroxybenzoic acid; PCAPolyphenol (Hydroxybenzoic Acid)AcaiEuterpe oleraceaFruit Pulp99-50-3ModerateStudied for antioxidant, anti-inflammatory, and potential cardioprotective properties; a metabolite of anthocyanins and cyanidin compounds in the gut.
Gentisic Acid2,5-Dihydroxybenzoic acidPolyphenol (Hydroxybenzoic Acid)GentianGentiana luteaRoots490-79-9ModerateStudied for anti-inflammatory and hepatoprotective properties; a salicylate-related compound with antioxidant activity.
Syringic Acid4-Hydroxy-3,5-dimethoxybenzoic acidPolyphenol (Hydroxybenzoic Acid)DatesPhoenix dactyliferaFruit530-57-4ModerateStudied for antioxidant and neuroprotective properties; a methylated hydroxybenzoic acid with good bioavailability from dietary sources.
Vanillic Acid4-Hydroxy-3-methoxybenzoic acidPolyphenol (Hydroxybenzoic Acid)Vanilla BeanVanilla planifoliaSeed Pod121-34-6ModerateStudied for antioxidant and anti-inflammatory properties; contributes to the health-relevant phenolic profile of vanilla and numerous plant foods.
3-O-Methylgallic Acid3-O-MGA; Methylated gallic acidPolyphenol (Hydroxybenzoic Acid)EucalyptusEucalyptus spp.Leaves3149-27-7EmergingStudied for antioxidant and antimicrobial properties in early-stage research; a methylated gallic acid derivative found in various plant species.
ELLAGITANNINS & GALLOTANNINS
PunicalaginAlpha/Beta-Punicalagin; Pomegranate tanninPolyphenol (Ellagitannin)PomegranatePunica granatumFruit Peel65995-63-3ModerateThe most abundant ellagitannin in pomegranate; studied for potent antioxidant, anti-inflammatory, and cardiovascular-supportive properties. One of the richest known dietary antioxidants.
CasuarictinStrawberry ellagitanninPolyphenol (Ellagitannin)StrawberryFragaria ananassaFruit79786-13-3ModerateAn ellagitannin found in strawberries and raspberries; studied for antioxidant and potential antiproliferative properties in the context of berry consumption.
Sanguiin H-6Red Raspberry ellagitanninPolyphenol (Ellagitannin)Red RaspberryRubus idaeusFruit82168-16-3ModerateA major ellagitannin in raspberries; studied for antioxidant and gut health-supportive properties following hydrolysis to ellagic acid in the gut.
CastalaginChestnut wood ellagitanninPolyphenol (Ellagitannin)ChestnutCastanea sativaWood / Husk18046-00-9ModerateStudied for antioxidant, antimicrobial, and blood glucose-modulating properties; found in oak and chestnut wood used in barrel-aged foods.
VescalaginOak wood ellagitanninPolyphenol (Ellagitannin)Oak WoodQuercus spp.Wood Tissue20229-29-4ModerateStudied for anti-inflammatory and cardioprotective properties; imparted to wine, spirits, and foods from oak barrel contact.
GeraniinCranesbill ellagitanninPolyphenol (Ellagitannin)CranesbillGeranium spp.Aerial Parts60976-49-0ModerateStudied for antihypertensive, antiviral, and immunomodulatory properties; the characteristic ellagitannin of Geranium species used in traditional medicine.
CorilaginPhyllanthus ellagitannin; Hepatoprotective tanninPolyphenol (Ellagitannin)PhyllanthusPhyllanthus emblicaFruit23094-69-1ModerateStudied for hepatoprotective and antiviral properties; contributes to the liver health benefits associated with Phyllanthus emblica (Amla) preparations.
PedunculaginWalnut ellagitanninPolyphenol (Ellagitannin)WalnutJuglans regiaPellicle (Skin)41743-41-3EmergingA walnut ellagitannin studied for antioxidant and cardiovascular-supportive properties; contributes to the polyphenol profile of whole walnuts.
GalloylglucosePentagalloylglucose; GallotanninPolyphenol (Gallotannin)RhubarbRheum rhabarbarumStalk / Root14937-32-7ModerateA gallotannin studied for antioxidant and digestive health-supporting properties; also studied for potential anti-inflammatory and anti-adipogenic effects.
LIGNANS
SecoisolariciresinolSECO; Flaxseed lignan precursorPolyphenol (Lignan)FlaxseedLinum usitatissimumSeed Coat80956-06-5ModerateA plant lignan converted by gut bacteria to the phytoestrogenic enterolignans enterodiol and enterolactone; studied for hormonal health and potential breast cancer risk modulation.
MatairesinolSesame lignan precursorPolyphenol (Lignan)Sesame SeedSesamum indicumSeed Husk580-72-3ModerateA dietary lignan that is converted to enterolactone by gut microbiota; may contribute to cardiovascular and hormonal health benefits associated with sesame consumption.
SesaminSesame primary lignanPolyphenol (Lignan)Sesame SeedSesamum indicumSeeds607-80-7ModerateThe primary lignan of sesame; studied for hepatoprotective, cholesterol-modulating, and antioxidant properties. May support healthy lipid metabolism.
PinoresinolOlive oil lignanPolyphenol (Lignan)Olive OilOlea europaeaFruit Oil6216-81-5ModerateStudied for antioxidant, blood glucose-modulating, and anti-inflammatory properties; contributes to the cardiovascular benefits associated with extra virgin olive oil consumption.
LariciresinolBroccoli lignan; Dietary lignanPolyphenol (Lignan)BroccoliBrassica oleraceaStems39459-36-6ModerateA dietary lignan studied for cardiovascular health support and phytoestrogenic activity; converted by gut microbiota to enterodiol.
SyringaresinolGrain lignan; Phytoestrogenic lignanPolyphenol (Lignan)Whole GrainsTriticum aestivumBran6216-81-5ModerateA grain lignan studied for oestrogen receptor-binding activity and potential cardiovascular-protective effects as part of whole grain consumption.
MedioresinolLemon lignan; Secoisolariciresinol relatedPolyphenol (Lignan)LemonCitrus limonFruit Juice14137-93-8EmergingA minor dietary lignan studied for antioxidant properties; contributes to the overall lignan intake associated with citrus consumption.
HonokiolMagnolia lignan; Anxiolytic lignanPolyphenol (Lignan)MagnoliaMagnolia officinalisBark35354-74-6ModerateA bioactive neolignan studied for anxiolytic, anti-inflammatory, and potential neuroprotective properties; may modulate GABA-A receptors with good CNS penetration.
MagnololMagnolia bark lignanPolyphenol (Lignan)MagnoliaMagnolia officinalisBark528-43-8ModerateStudied for CNS-calming, anti-neuroinflammatory, and antioxidant properties; used alongside honokiol in traditional Chinese medicine preparations for anxiety and sleep support.
SchisandrinSchisandrin A; Wuweizisu APolyphenol (Lignan)SchisandraSchisandra chinensisBerries7432-28-2ModerateThe primary dibenzocyclooctadiene lignan of Schisandra; studied for hepatoprotective, adaptogenic, and cognitive-supporting properties with a moderate evidence base.
ArctigeninBurdock aglycone lignanPolyphenol (Lignan)BurdockArctium lappaSeeds7770-78-7ModerateStudied for thermogenic, antiviral, and anti-inflammatory properties; may contribute to the traditional use of burdock for metabolic and immune support.
MacelignanNutmeg lignan; Methylenedioxyphenyl lignanPolyphenol (Lignan)NutmegMyristica fragransSeeds68247-50-7ModerateStudied for UV photoprotective and prostaglandin synthesis-inhibiting properties; contributes to the skin health-relevant profile of nutmeg preparations.
PHENYLETHANOIDS & SECOIRIDOIDS
Hydroxytyrosol3,4-DHPEA; Olive polyphenolPolyphenol (Phenylethanoid)OliveOlea europaeaFruit Juice10597-60-1HighA highly bioavailable olive polyphenol with one of the highest recorded antioxidant activities among dietary compounds; associated with cardiovascular protection. Carries an EU health claim for LDL oxidation protection.
OleuropeinOlive leaf phenolic; Bitter glucosidePolyphenol (Secoiridoid)Olive LeafOlea europaeaLeaf Tissue32619-42-4ModerateThe dominant phenolic of olive leaf; studied for antihypertensive, antioxidant, and antimicrobial properties with an established traditional and emerging clinical evidence base.
Oleocanthalp-HPEA-EDA; EVOO phenolic aldehydePolyphenol (Phenylethanoid)Extra Virgin Olive OilOlea europaeaFruit Oil289030-99-5ModerateStudied for COX-1 and COX-2 inhibitory activity analogous to ibuprofen; the compound responsible for the peppery throat sensation of high-quality extra virgin olive oil.
RosavinRosavins; Rhodiola phenylpropanoidPolyphenol (Phenylpropanoid)RhodiolaRhodiola roseaRoots84954-92-7ModerateOne of the marker compounds of Rhodiola rosea; studied for adaptogenic properties including cortisol modulation and enhancement of physical and mental endurance.
SalidrosideRhodioloside; Rhodiola tyrosol glucosidePolyphenol (Phenylethanoid Glycoside)RhodiolaRhodiola roseaRoots10338-51-9ModerateThe primary bioactive of Rhodiola rosea; studied for adaptogenic, neuroprotective, and antifatigue properties with a growing human clinical evidence base.
VerbascosideActeoside; Mullein phenylethanoidPolyphenol (Phenylethanoid)MulleinVerbascum thapsusLeaves61276-17-3ModerateA widely distributed phenylethanoid glycoside studied for antioxidant, anti-inflammatory, and potential neuroprotective properties; found in numerous medicinal plants.
EchinacosideCistanche phenylethanoid; NeuroprotectivePolyphenol (Phenylethanoid)Desert HyacinthCistanche tubulosaStem82854-37-3ModerateA phenylethanoid glycoside studied for neuroprotective, neurotrophic, and cognitive-supporting properties; used in traditional Chinese and Ayurvedic medicine for longevity support.
ActeosideVerbascoside; Phenylethanoid glycosidePolyphenol (Phenylethanoid)Forsythia / OliveForsythia suspensaLeaves61276-17-3ModerateA widely found phenylethanoid studied for hepatoprotective, antiviral, and anti-inflammatory properties across multiple traditional medicine systems.
CURCUMINOIDS & MISCELLANEOUS POLYPHENOLS
CurcuminDiferuloylmethane; Turmeric Yellow; E100Polyphenol (Curcuminoid)TurmericCurcuma longaRhizome458-37-7ModerateA polyphenolic diarylheptanoid studied extensively for anti-inflammatory and antioxidant properties; poor oral bioavailability without formulation enhancement limits effects from standard preparations.
BisdemethoxycurcuminCurcumin III; Turmeric curcuminoidPolyphenol (Curcuminoid)TurmericCurcuma longaRhizome33171-16-3ModerateA minor curcuminoid studied for antioxidant and anti-inflammatory properties comparable to curcumin; part of the standardised curcumin extract complex.
DemethoxycurcuminCurcumin II; Turmeric curcuminoidPolyphenol (Curcuminoid)TurmericCurcuma longaRhizome22608-11-3ModerateAn intermediate curcuminoid studied for anti-inflammatory properties; contributes to the biological activity of standardised curcumin preparations.
Oleuropein AglyconeElenolic acid derivative; OAPolyphenol (Secoiridoid)OliveOlea europaeaFruit / LeafModerateThe more bioavailable aglycone form of oleuropein; studied for potent antioxidant, antihypertensive, and potential anti-amyloid properties.
LigustilideSichuan Lovage phthalide; LIGPolyphenol (Phthalide)LigusticumLigusticum chuanxiongRhizome4431-01-0ModerateA phthalide studied for smooth muscle-relaxing, vasodilatory, and neuroprotective properties; the primary active compound of Chuanxiong herb.
HEMITERPENES
Isoprene2-Methyl-1,3-butadiene; Foliage volatileTerpenoid (Hemiterpene)AspenPopulus tremuloidesLeaves78-79-5EmergingThe simplest biological terpene; released by plants under heat stress. Studied for its role in atmospheric chemistry and plant stress signalling.
Angelic Acid(Z)-2-Methylbut-2-enoic acid; Angelica acidTerpenoid (Hemiterpene)Garden AngelicaAngelica archangelicaRoots565-63-9ModerateStudied for sedative and antispasmodic properties; contributes to the calming activity of Angelica root preparations used traditionally.
Tiglic Acid(E)-2-Methylbut-2-enoic acid; Croton acidTerpenoid (Hemiterpene)CrotonCroton tigliumSeed Oil80-59-1EmergingA minor monoterpenoid acid studied for metabolic signalling activity; present in various plant essential oils and examined for anti-inflammatory potential.
Isovaleric Acid3-Methylbutanoic acid; Valerian acidTerpenoid (Hemiterpene)ValerianValeriana officinalisRhizomes503-74-2ModerateStudied for GABAergic activity contributing to the sedative and anxiolytic properties of valerian root preparations; also a minor fermentation metabolite.
MONOTERPENES
LimoneneD-Limonene; (+)-Limonene; Citrus terpeneTerpenoid (Monoterpene)Lemon / OrangeCitrus limon / sinensisFruit Peel Oil5989-27-5ModerateStudied for potential chemopreventive and digestive health-supporting properties; widely used in food, fragrance, and wellness applications. Emerging human trial data available.
Alpha-Pinenealpha-Pinene; Pine resin monoterpeneTerpenoid (Monoterpene)Pine TreePinus sylvestrisResin / Bark80-56-8ModerateThe most abundant monoterpene in nature; studied for bronchodilatory, anti-inflammatory, and potential memory-supporting properties via acetylcholinesterase inhibition.
Beta-Pinenebeta-Pinene; Piney monoterpeneTerpenoid (Monoterpene)Rosemary / PineSalvia rosmarinusLeaves / Resin127-91-3ModerateStudied for antimicrobial and antifungal properties; contributes to the respiratory-supportive and antiseptic activity of pine and rosemary preparations.
Linalool3,7-Dimethyl-1,6-octadien-3-ol; Lavender terpeneTerpenoid (Monoterpene)LavenderLavandula angustifoliaFlowers78-70-6ModerateStudied for anxiolytic and sedative-supportive properties via modulation of GABA-A receptors; a key aromatic component of lavender with some human trial evidence for stress reduction.
MentholL-Menthol; Peppermint terpene alcoholTerpenoid (Monoterpene)PeppermintMentha x piperitaLeaves89-78-1HighA TRPM8 receptor agonist used clinically as a topical analgesic and counterirritant; well-established for sore throat relief, nasal decongestion, and IBS symptom support.
Camphor(+)-Camphor; Bornone; Camphor tree terpeneTerpenoid (Monoterpene)Camphor TreeCinnamomum camphoraBark / Wood76-22-2HighA clinically used topical analgesic and mild counterirritant; incorporated in numerous licensed topical preparations for musculoskeletal discomfort and nasal decongestion.
Thymol2-Isopropyl-5-methylphenol; Thyme phenolTerpenoid (Monoterpene)ThymeThymus vulgarisLeaves89-83-8HighA potent antimicrobial monoterpene with established activity against oral bacteria; used in licensed dental antiseptic preparations and studied for respiratory health support.
Carvacrol2-Methyl-5-(1-methylethyl)phenol; Oregano phenolTerpenoid (Monoterpene)OreganoOriganum vulgareLeaves499-75-2ModerateStudied for antimicrobial, anti-inflammatory, and gut health-supporting properties; may help maintain a healthy gut microbial balance and support mucosal integrity.
Geraniol(E)-3,7-Dimethyl-2,6-octadien-1-ol; Rose terpeneTerpenoid (Monoterpene)Geranium / RosePelargonium graveolensFlowers106-24-1ModerateStudied for antimicrobial, antioxidant, and potential antiproliferative properties; widely used in aromatherapy and personal care formulations for its floral fragrance.
Eucalyptol1,8-Cineole; Cineole; Eucalyptus terpeneTerpenoid (Monoterpene)EucalyptusEucalyptus globulusLeaves470-82-6HighA clinically studied mucolytic and bronchosecretolytic agent; incorporated in licensed respiratory preparations for cough and bronchitis support. Evidence from multiple human trials.
Terpinen-4-olTea Tree primary component; p-Menth-1-en-4-olTerpenoid (Monoterpene)Tea TreeMelaleuca alternifoliaLeaves562-74-3HighThe primary antimicrobial constituent of tea tree oil; well-supported clinically for topical bacterial and fungal skin infections, acne, and wound care.
Hinokitiolbeta-Thujaplicin; Cypress terpeneTerpenoid (Monoterpene)CypressChamaecyparis obtusaHeartwood499-44-5ModerateStudied for broad-spectrum antimicrobial and antifungal properties; used in oral hygiene and skincare formulations. Chelates iron to deprive bacteria of a key growth nutrient.
SabineneSabinene; Black pepper monoterpeneTerpenoid (Monoterpene)Black PepperPiper nigrumDried Fruits3387-41-5EmergingA bicyclic monoterpene contributing to the spicy aroma of pepper and several essential oils; studied for antioxidant properties in early-stage research.
Thujonealpha-Thujone; Wormwood terpeneTerpenoid (Monoterpene)WormwoodArtemisia absinthiumAerial Parts546-80-5ModerateA GABA-A receptor modulator associated with the historical effects of absinthe; toxic at high doses. Subject to regulatory limits in food and beverages.
Myrcenebeta-Myrcene; Hops / Lemongrass terpeneTerpenoid (Monoterpene)Hops / LemongrassHumulus lupulusFlowers / Leaves123-35-3ModerateStudied for sedative and muscle relaxant properties; may enhance cellular permeability to aid absorption of co-administered compounds.
Terpineolalpha-Terpineol; Pine terpene alcoholTerpenoid (Monoterpene)Lilac / PineSyringa vulgarisFlowers / Sap98-55-5ModerateStudied for antimicrobial, anxiolytic, and anti-inflammatory properties; used in aromatherapy and studied for nervous system calming effects in animal models.
Citronellol(R)-(-)-Citronellol; Citronella monoterpeneTerpenoid (Monoterpene)Citronella / RoseCymbopogon nardusLeaves106-22-9ModerateStudied for insect-repellent, antispasmodic, and antimicrobial properties; a primary component of commercial natural mosquito repellent preparations.
Perillyl Alcoholp-Menth-1-en-7-ol; Lavender terpene alcoholTerpenoid (Monoterpene)LavenderLavandula angustifoliaFlowers536-59-4ModerateStudied for potential chemopreventive properties via Ras pathway modulation; clinical trials have been conducted for several cancer types though results are mixed.
MenthoneL-Menthone; Peppermint terpene ketoneTerpenoid (Monoterpene)PeppermintMentha x piperitaLeaves14073-97-3ModerateA ketone monoterpene studied for antimicrobial and digestive comfort-supporting properties; contributes to the overall pharmacological activity of peppermint oil.
BorneolEndo-borneol; Camphor reduction productTerpenoid (Monoterpene)Borneol CamphorDryobalanops aromaticaResin507-70-0ModerateStudied for neurological effects including CNS-penetrating anti-inflammatory properties; used in traditional Chinese medicine to enhance drug delivery to the brain.
Nerolidol(E)-Nerolidol; Lemon grass sesquiterpeneTerpenoid (Sesquiterpene)LemongrassCymbopogon citratusLeaves40716-66-3ModerateStudied for antimicrobial, anti-inflammatory, and potential skin-penetration-enhancing properties; of interest for topical drug delivery research.
IRIDOIDS (MONOTERPENE GLYCOSIDES)
AucubinAucuboside; Plantain iridoidTerpenoid (Iridoid)PlantainPlantago majorLeaves479-98-1ModerateStudied for hepatoprotective, anti-inflammatory, and antiallergic properties; may support liver cell protection and contribute to a healthy inflammatory response.
CatalpolRehmannia iridoid; NeuroprotectiveTerpenoid (Iridoid)RehmanniaRehmannia glutinosaRoots2415-24-9ModerateStudied for neuroprotective properties including protection of dopaminergic and cholinergic neurons; contributes to the cognitive health-supportive use of Rehmannia root.
GeniposideGardenia iridoid glycosideTerpenoid (Iridoid)GardeniaGardenia jasminoidesFruit24512-63-8ModerateStudied for antidiabetic, analgesic, and hepatoprotective properties; contributes to the blood sugar-modulating and liver-protective traditional uses of Gardenia.
LoganinStrychnos iridoid; MIA precursorTerpenoid (Iridoid)Strychnine TreeStrychnos nux-vomicaSeeds18524-94-2ModerateA biosynthetic precursor to monoterpenoid indole alkaloids in plants; studied for neuroprotective and antidiabetic properties in early-stage research.
HarpagosideDevil's Claw primary iridoidTerpenoid (Iridoid)Devil's ClawHarpagophytum procumbensTubers19716-97-7HighThe primary bioactive of Devil's Claw; well-supported by clinical trials for osteoarthritis and chronic low back pain management. European regulatory recognition for joint health.
SwertiamarinGentian bitter iridoidTerpenoid (Iridoid)GentianGentiana luteaRoots17388-39-5ModerateA secoiridoid glycoside that stimulates gastric acid and bile secretion; supports the traditional use of gentian root as a digestive bitter and hepatoprotective agent.
NepetalactoneCatnip iridoid; Feline attractantTerpenoid (Iridoid)CatnipNepeta catariaLeaves490-52-8ModerateStudied for insect-repellent properties; more effective than DEET against certain mosquito species in some laboratory studies. Also causes the characteristic behavioural response in domestic cats.
SESQUITERPENES
ArtemisininQHS; Qinghaosu; ArtemisininTerpenoid (Sesquiterpene Lactone)Sweet WormwoodArtemisia annuaLeaves / Seeds63968-64-9HighA Nobel Prize-recognised antimalarial; its endoperoxide bridge is activated by haem iron in Plasmodium parasites to produce toxic radical species. Forms the basis for WHO-recommended artemisinin combination therapies.
Beta-Caryophyllene(E)-BCP; CB2 agonist terpeneTerpenoid (Sesquiterpene)Black Pepper / ClovePiper nigrumFruit / Bud87-44-5ModerateA dietary CB2 receptor agonist studied for anti-inflammatory and analgesic properties without psychoactive effects; the first dietary compound identified as a cannabinoid receptor ligand.
Alpha-Humulenealpha-Caryophyllene; Hops sesquiterpeneTerpenoid (Sesquiterpene)Hops / SageHumulus lupulusFlowers6753-98-6ModerateStudied for anti-inflammatory and potential appetite-suppressing properties; contributes to the anti-inflammatory profile of hops alongside beta-caryophyllene.
Farnesol(E,E)-Farnesol; Floral sesquiterpeneTerpenoid (Sesquiterpene)Rose / CitronellaRosa damascenaFlowers4602-84-0ModerateStudied for antimicrobial, antifungal, and potential antiproliferative properties; also acts as a quorum sensing inhibitor in bacterial biofilms.
Bisabolol(-)-alpha-Bisabolol; Chamomile sesquiterpeneTerpenoid (Sesquiterpene)ChamomileMatricaria chamomillaFlowers23089-26-1ModerateStudied for skin-soothing, anti-inflammatory, and wound-healing properties; widely used in cosmetic preparations for sensitive and irritated skin.
ParthenolideFeverfew sesquiterpene lactoneTerpenoid (Sesquiterpene Lactone)FeverfewTanacetum partheniumLeaves20554-84-1ModerateStudied for NF-kB inhibition, anti-migraine, and potential leukaemia stem cell-targeting properties; the primary bioactive of feverfew with moderate clinical evidence for migraine prevention.
HelenalinArnica sesquiterpene lactoneTerpenoid (Sesquiterpene Lactone)ArnicaArnica montanaFlowers6754-13-8ModerateA potent anti-inflammatory sesquiterpene lactone; supports the topical use of arnica for bruising, muscle soreness, and minor injury management. Toxic if taken internally.
CynaropicrinArtichoke bitter sesquiterpeneTerpenoid (Sesquiterpene Lactone)ArtichokeCynara scolymusLeaves35688-04-1ModerateStudied for hepatoprotective, choleretic, and lipid-modulating properties; contributes to the liver and digestive health benefits of artichoke leaf extracts.
ThapsigarginSERCA pump inhibitor; Deadly CarrotTerpenoid (Sesquiterpene Lactone)Deadly CarrotThapsia garganicaRoots67526-95-8EmergingA potent SERCA pump inhibitor studied in oncological research; forms the basis for targeted drug delivery conjugates in prostate cancer research. Not for unsupervised use — toxic at very low doses.
GossypolCotton sesquiterpene aldehyde; Male contraceptiveTerpenoid (Sesquiterpene)CottonGossypium hirsutumSeeds / Roots303-45-7ModerateA dimeric sesquiterpene studied for male contraceptive and antiproliferative properties; associated with infertility-inducing effects in clinical research. Subject to significant safety concerns.
ValtrateValerian IVHD-valtrate; Iridoid esterTerpenoid (Sesquiterpene)ValerianValeriana officinalisRoots18296-44-1ModerateStudied for sedative and anxiolytic-supportive properties via GABAergic modulation; contributes to the sleep quality-supporting evidence base of valerian root preparations.
ChamazuleneBlue Chamomile azuleneTerpenoid (Sesquiterpene)German ChamomileMatricaria chamomillaDistilled Oil529-05-5ModerateFormed during steam distillation of chamomile; the compound responsible for the characteristic blue colour of the essential oil. Studied for anti-inflammatory and antiallergic properties.
CostunolideCostus sesquiterpene lactoneTerpenoid (Sesquiterpene Lactone)CostusSaussurea costusRoots553-21-9ModerateStudied for anti-inflammatory, anti-angiogenic, and antiproliferative properties in preclinical cancer research; contributes to the traditional anti-inflammatory uses of Costus root.
SantoninLevant Wormseed anthelminthicTerpenoid (Sesquiterpene Lactone)Levant WormseedArtemisia cinaFlower Buds481-06-1HighA clinically established anthelminthic historically used to paralyse and expel intestinal roundworms; now largely superseded by modern anthelmintics due to toxicity concerns at effective doses.
ZingibereneGinger sesquiterpene; BisabolaneTerpenoid (Sesquiterpene)GingerZingiber officinaleRhizome495-60-3ModerateA primary sesquiterpene of ginger; studied for antiemetic and gastrointestinal-soothing properties, contributing to the well-documented benefit of ginger for nausea management.
CurzereneMyrrh sesquiterpene; GermacranolideTerpenoid (Sesquiterpene)MyrrhCommiphora myrrhaResin6902-72-3ModerateStudied for analgesic and anti-inflammatory properties; may interact with opioid receptors to contribute to pain relief. Part of the complex pharmacology of myrrh resin.
AlantolactoneElecampane sesquiterpene; HeleninTerpenoid (Sesquiterpene Lactone)ElecampaneInula heleniumRoots546-43-0ModerateStudied for expectorant, antimicrobial, and potential antiparasitic properties; supports the traditional use of elecampane for deep respiratory tract infections.
GermacroneZedoary sesquiterpene ketoneTerpenoid (Sesquiterpene)ZedoaryCurcuma zedoariaRhizome6902-72-3ModerateStudied for anti-inflammatory and potential antiviral properties; contributes to the traditional use of zedoary rhizome in digestive and respiratory wellness.
GuaiolGuaiacum sesquiterpene alcoholTerpenoid (Sesquiterpene)GuaiacumGuaiacum officinaleWood / Oil489-86-1ModerateStudied for anti-inflammatory and potential antibacterial properties; a naturally occurring sesquiterpene alcohol with historical use in respiratory and joint health preparations.
SESTERTERPENES
Ophiobolin ASesterterpenoid; Fungal toxinTerpenoid (Sesterterpene)Brown Spot FungusBipolaris oryzaeFungal Cells4611-05-6EmergingA highly cytotoxic fungal sesterterpene studied in early-stage oncological research for its potential to disrupt cancer cell membrane integrity; extremely toxic, preclinical research only.
ManoalideMarine sesterterpene; PLA2 inhibitorTerpenoid (Sesterterpene)Marine SpongeLuffariella variabilisWhole Organism76055-64-6EmergingA potent phospholipase A2 inhibitor from a marine sponge; studied as a molecular template for anti-inflammatory drug development. Not a plant source — included for completeness.
Leucosceptroid AHimalayan Mint sesterterpeneTerpenoid (Sesterterpene)Himalayan MintLeucosceptrum canumLeaf HairsEmergingAn insect-feeding deterrent sesterterpene from Leucosceptrum; studied as a natural pest management compound with early-stage research interest.
DITERPENES
PaclitaxelTaxol; Bristol-Myers anticancer drugTerpenoid (Diterpene Taxane)Pacific YewTaxus brevifoliaBark / Roots33069-62-4HighA clinically approved microtubule-stabilising chemotherapy agent used for breast, ovarian, lung, and other cancers; one of the most significant plant-derived pharmaceutical discoveries.
Ginkgolide BBN 52021; Ginkgo PAF antagonistTerpenoid (Diterpene)GinkgoGinkgo bilobaLeaves / Seeds15291-77-7ModerateStudied for platelet-activating factor (PAF) antagonism; the primary active ginkgolide contributing to Ginkgo extract's cardiovascular and cognitive-supportive evidence base.
ForskolinColeonol; Coleus diterpeneTerpenoid (Diterpene)ColeusColeus forskohliiRoots66575-29-9ModerateA potent adenylyl cyclase activator studied for cardiovascular, respiratory, and potential weight management support; used as a pharmacological research tool and in herbal supplements.
Salvinorin ASalA; Diviner's Sage kappa-agonistTerpenoid (Diterpene)Diviner's SageSalvia divinorumLeaves83729-01-5EmergingA highly potent selective kappa-opioid receptor agonist associated with intense dissociative and perceptual alterations; the first non-nitrogenous compound with potent psychedelic activity. Controlled substance in many jurisdictions.
Abietic AcidSylvic acid; Rosin acidTerpenoid (Diterpene)PinePinus spp.Resin514-10-3ModerateThe primary resin acid of pine; studied for antimicrobial and anti-inflammatory properties. The main commercial component of rosin used in pharmaceuticals, adhesives, and food coatings.
Carnosic AcidRosemary antioxidant diterpeneTerpenoid (Diterpene)RosemaryRosmarinus officinalisLeaves3650-09-7ModerateStudied for neuroprotective and antioxidant properties via Nrf2 pathway activation; the primary lipophilic antioxidant of rosemary with potential relevance to cognitive health.
AndrographolideKing of Bitters; AP; Andrographis lactoneTerpenoid (Diterpene Lactone)King of BittersAndrographis paniculataLeaves5508-58-7ModerateStudied for antiviral, anti-inflammatory, and immunostimulatory properties; multiple clinical trials support its use for upper respiratory tract infection symptom reduction.
SteviolSteviol diterpene; Stevia aglyconeTerpenoid (Diterpene)SteviaStevia rebaudianaLeaves471-80-7HighThe diterpene aglycone backbone of steviol glycosides; its glycosylated derivatives are clinically safe, non-caloric sweeteners with established safety profiles and regulatory approval in numerous markets.
CafestolCoffee diterpene; Kahweol companionTerpenoid (Diterpene)CoffeeCoffea arabicaBean (Unfiltered)469-83-0ModerateStudied for hepatoprotective, antioxidant, and potential cancer chemopreventive properties; also associated with elevated LDL cholesterol when consumed in unfiltered coffee.
KahweolCoffee diterpene; AntioxidantTerpenoid (Diterpene)CoffeeCoffea arabicaBean (Unfiltered)6894-43-5ModerateStudied alongside cafestol for protective effects on DNA oxidation and potential support for healthy inflammatory balance; imparts similar LDL-elevating effects in unfiltered preparations.
SclareolClary Sage diterpene diolTerpenoid (Diterpene)Clary SageSalvia sclareaFlowers / Leaves515-03-7ModerateStudied for oestrogenic and potential cytotoxic properties; traditionally used for hormonal balance support. Also a valued fixative in fragrance production.
CarnosolRosemary diterpene phenolTerpenoid (Diterpene)RosemaryRosmarinus officinalisLeaves5957-80-2ModerateStudied for Nrf2-activating antioxidant, anti-inflammatory, and potential antiproliferative properties; works synergistically with carnosic acid in rosemary preparations.
Tanshinone IIADanshen primary diterpeneTerpenoid (Diterpene)DanshenSalvia miltiorrhizaRoots568-72-9ModerateStudied for cardiovascular protective and anti-inflammatory properties; a key bioactive of Danshen (Red Sage) widely used in Traditional Chinese Medicine and subject to clinical investigation in China.
TRITERPENES & TRITERPENOID SAPONINS
SqualeneSpinacene; Supraene; C30 triterpeneTerpenoid (Triterpene)Olive OilOlea europaeaFruit111-02-4ModerateA triterpene hydrocarbon and precursor to all plant sterols and triterpenoids; studied for skin-moisturising, antioxidant, and potential immune-supportive properties.
GlycyrrhizinGlycyrrhizic acid; Licorice saponinTerpenoid (Triterpenoid Saponin)LicoriceGlycyrrhiza glabraRoots1405-86-3HighA triterpenoid saponin used clinically in Japan (as glycyrrhizin IV) for chronic hepatitis B and C management; also the primary sweetening compound of licorice root.
Ginsenoside Rb1Rb1; Ginseng protopanaxadiol saponinTerpenoid (Triterpenoid Saponin)GinsengPanax ginsengRoots41753-43-9ModerateThe most abundant ginsenoside; studied for neuroprotective, anti-stress, and metabolic support properties. Part of the evidence base for Panax ginseng as an adaptogen.
Ginsenoside Rg1Rg1; Ginseng protopanaxatriol saponinTerpenoid (Triterpenoid Saponin)GinsengPanax ginsengRoots22427-39-0ModerateStudied for cognitive-supportive and anti-fatigue properties; may promote hippocampal neurogenesis. Contributes to the clinical evidence for ginseng in mental performance.
CelastrolTripterine; Thunder God Vine triterpeneTerpenoid (Triterpene)Thunder God VineTripterygium wilfordiiRoots34157-83-0EmergingStudied in early-stage research for potent anti-obesity and anti-inflammatory properties; associated with significant toxicity that limits therapeutic application without delivery formulation.
Asiatic AcidAsiaticoside aglycone; Gotu Kola triterpeneTerpenoid (Triterpene)Gotu KolaCentella asiaticaLeaves464-92-6ModerateStudied for collagen synthesis-stimulating, wound-healing, and neuroprotective properties; supports the evidence base for Centella asiatica in skin repair and cognitive health.
AsiaticosideGotu Kola triterpenoid saponinTerpenoid (Triterpenoid Saponin)Gotu KolaCentella asiaticaLeaves16830-15-2ModerateThe glycosylated form of asiatic acid; studied for wound healing and venous insufficiency support. The primary bioactive in licensed Centella asiatica wound care preparations.
Ganoderic Acid AReishi triterpene; Ganoderma acidTerpenoid (Triterpene)Reishi MushroomGanoderma lucidumFruiting Body81907-62-2ModerateOne of many ganoderic acids studied for immunomodulatory, hepatoprotective, and antihypertensive properties; contributes to the clinical evidence base for Reishi mushroom preparations.
EscinAescin; Horse Chestnut saponinTerpenoid (Triterpenoid Saponin)Horse ChestnutAesculus hippocastanumSeeds6805-41-0HighWell-supported by multiple RCTs for chronic venous insufficiency management; strengthens capillary walls and reduces oedema via inhibition of lysosomal enzymes.
Boswellic AcidAKBA; Acetyl-keto-boswellic acid; FrankincenseTerpenoid (Triterpene)FrankincenseBoswellia serrataResin631-69-6HighA 5-LOX inhibitor with well-documented anti-inflammatory activity; clinical trials support its use for osteoarthritis and inflammatory bowel conditions. Carries EU traditional herbal medicine status.
Corosolic AcidBanaba triterpene; Anti-diabeticTerpenoid (Triterpene)BanabaLagerstroemia speciosaLeaves4547-24-4ModerateStudied for insulin-sensitising and blood glucose-modulating properties; may support healthy postprandial glucose management via glucose transporter activation.
Cucurbitacin ECucurbitacin; Bitter Melon triterpeneTerpenoid (Triterpene)Bitter Melon / SquashMomordica charantiaFruit / Roots18444-66-1EmergingA highly bitter defense compound studied for STAT3 and actin cytoskeleton disruption in cancer cell research; associated with significant gastrointestinal irritancy at low doses.
LimoninCitrus limonoid; Bitter citrus triterpeneTerpenoid (Triterpenoid Limonoid)Lemon / LimeCitrus limonSeeds1180-71-8ModerateStudied for antiviral, immune-modulating, and potential anticancer properties; the primary bitterness compound in citrus seeds that reduces on ripening.
DiosgeninFenugreek steroidal saponin aglyconeTerpenoid (Triterpenoid Saponin)FenugreekTrigonella foenum-graecumSeeds512-04-9ModerateA steroidal saponin aglycone used industrially as a starting material for semi-synthesis of progesterone and other steroid hormones; also studied for direct cholesterol-modulating properties.
LanosterolBiosynthetic sterol precursor; Cataract researchTerpenoid (Triterpene)Lanosulin source / Tea SeedCamellia sinensisSeeds (Oil)79-63-0EmergingA biosynthetic precursor to all animal and fungal sterols; studied in early-stage research for its potential to reverse protein aggregation in lens cataracts.
NimbinNeem triterpenoidTerpenoid (Triterpene)NeemAzadirachta indicaSeeds / Oil5945-86-8ModerateA tetranortriterpenoid studied for insecticidal, antimicrobial, and antifungal properties; contributes to the broad-spectrum biological activity of neem oil preparations.
FriedelinCork Oak triterpenoidTerpenoid (Triterpene)Cork OakQuercus suberBark / Leaves559-74-0ModerateA pentacyclic triterpenoid studied for anti-inflammatory, analgesic, and hepatoprotective properties; used in traditional medicine for digestive and liver health support.
Betulinic Acid3-beta-Hydroxy-lup-20(29)-en-28-oic acidTerpenoid (Triterpene)White BirchBetula pubescensBark / Twigs472-15-1ModerateStudied for selective antiproliferative effects on melanoma cells and potential antiviral properties; of continuing interest in dermatological and oncological research.
LupeolFagarasterol; Mango triterpeneTerpenoid (Triterpene)Mango / NeemMangifera indicaFruit Pulp / Peel545-47-1ModerateStudied for anti-inflammatory, anti-angiogenic, and skin-protective properties; may contribute to the photoprotective benefits of mango peel polyphenol extracts.
Ursolic AcidUrson; Apple peel triterpeneTerpenoid (Triterpene)Apple / RosemaryMalus domesticaFruit Peel / Leaves77-52-1ModerateStudied for muscle mass preservation, fat metabolism support, and anti-inflammatory properties; of interest in sports nutrition and metabolic health research.
Oleanolic AcidCaryophyllin; Olive triterpeneTerpenoid (Triterpene)Olive TreeOlea europaeaLeaves508-02-1ModerateStudied for hepatoprotective and antimicrobial properties; contributes to the liver-protective activity of olive leaf preparations alongside oleuropein.
PHYTOSTEROLS
Beta-Sitosterolbeta-Sitosterol; 24-Ethylcholesterol; PhytosterolTerpenoid (Phytosterol)Wheat Germ / NettleTriticum aestivum / Urtica dioicaSeed / Root83-46-5HighThe most studied phytosterol; competes with cholesterol for intestinal absorption and supports prostate health via 5-alpha-reductase inhibition. Regulatory-approved for cholesterol reduction in food products.
StigmasterolPhytosterol; Soy sterolTerpenoid (Phytosterol)Soybean / Calabar BeanGlycine maxSeeds83-48-7ModerateA plant sterol studied for cholesterol-lowering, anti-inflammatory, and hormone precursor properties; used as a biosynthetic starting material for pharmaceutical steroid production.
Campesterol24-Methylcholesterol; Brassica sterolTerpenoid (Phytosterol)Canola / MustardBrassica napusSeeds474-62-4ModerateA phytosterol that may contribute synergistically to healthy cholesterol management when consumed as part of a sterol-rich diet or supplement.
BrassicasterolRapeseed phytosterol; 22-DehydroergosterolTerpenoid (Phytosterol)RapeseedBrassica napusSeeds474-67-9ModerateA Brassica-specific phytosterol studied for lipid profile management; also used as a chemotaxonomic biomarker for identifying Brassica-derived oils.
SpinasterolSpinach phytosterol; Delta-7-stigmastenolTerpenoid (Phytosterol)SpinachSpinacia oleraceaLeaves481-18-5ModerateA delta-7-phytosterol studied for anti-inflammatory and potential antiulcer properties; a characteristic sterol of spinach and certain other green leafy vegetables.
TETRATERPENES (CAROTENOIDS)
Beta-CaroteneProvitamin A; beta,beta-Carotene; E160aTerpenoid (Tetraterpene / Carotenoid)Carrot / PumpkinDaucus carotaRoot / Fruit7235-40-7HighA provitamin A carotenoid supporting healthy vision and immune function; well-documented antioxidant. Supplemental doses in smokers are associated with increased lung cancer risk — caution warranted.
Alpha-Carotenealpha,beta-CaroteneTerpenoid (Tetraterpene / Carotenoid)Carrot / Winter SquashDaucus carotaRoot / Pulp7488-99-5ModerateA provitamin A carotenoid with lower conversion efficiency than beta-carotene; epidemiological data suggest it may support longevity and healthy cell growth.
LycopenePsi,psi-Carotene; E160d; Tomato redTerpenoid (Tetraterpene / Carotenoid)Tomato / WatermelonSolanum lycopersicumFruit502-65-8HighA well-studied antioxidant carotenoid; consistently associated with cardiovascular protection and potential prostate health support in observational studies and some clinical trials.
LuteinXanthophyll; E161b; Marigold pigmentTerpenoid (Tetraterpene / Carotenoid)Kale / SpinachBrassica oleraceaLeaves127-40-2HighAccumulates selectively in the macular pigment; well-supported by clinical evidence for reducing risk of age-related macular degeneration and supporting visual function.
Zeaxanthin(3R,3'R)-Zeaxanthin; E161hTerpenoid (Tetraterpene / Carotenoid)Corn / PeppersZea maysSeeds / Fruit144-68-3HighA macular carotenoid studied alongside lutein for visual acuity support and photoprotection of the retina; part of the well-validated AREDS2 supplement evidence base.
Astaxanthin(3S,3'S)-Astaxanthin; Marine carotenoidTerpenoid (Tetraterpene / Carotenoid)Red AlgaeHaematococcus pluvialisWhole Cell472-61-7HighA ketocarotenoid with exceptional antioxidant potency; multiple human trials support its benefits for skin photoprotection, muscle recovery, and eye health.
FucoxanthinMarine xanthophyll; Brown seaweed pigmentTerpenoid (Tetraterpene / Carotenoid)Brown SeaweedUndaria pinnatifidaFronds3351-86-8ModerateA marine xanthophyll studied for thermogenic fat metabolism-supporting properties; may promote oxidation of white adipose tissue. Limited but emerging human clinical data.
CrocinGardenia yellow; Saffron carotenoid diesterTerpenoid (Tetraterpene / Carotenoid)SaffronCrocus sativusFlower Stigma42553-65-1ModerateThe primary pigment of saffron; studied for neuroprotective, antidepressant, and cognitive-supportive properties with a growing number of human clinical trials.
NeoxanthinXanthophyll; Green leaf carotenoidTerpenoid (Tetraterpene / Carotenoid)SpinachSpinacia oleraceaLeaves14646-79-8ModerateAn allenic xanthophyll found in green leafy vegetables; studied for antioxidant activity and potential contributions to carotenoid metabolite diversity in human tissues.
ViolaxanthinZeaxanthin diepoxide; Pansy pigmentTerpenoid (Tetraterpene / Carotenoid)PansyViola tricolorFlowers126-29-4ModerateAn epoxidised xanthophyll studied for antioxidant and potential antiproliferative properties; converts to zeaxanthin via the xanthophyll cycle in plant chloroplasts.
Capsanthin(3R,3'S,5'R)-Capsanthin; Red pepper pigmentTerpenoid (Tetraterpene / Carotenoid)Paprika / Bell PepperCapsicum annuumFruit465-42-9ModerateThe primary carotenoid pigment of red peppers; studied for HDL-raising and potential antioxidant and anti-inflammatory properties when consumed as part of a varied diet.
BixinNorbixin precursor; Annatto pigment; E160bTerpenoid (Tetraterpene / Carotenoid)AnnattoBixa orellanaSeed Coating6983-79-5ModerateThe primary orange pigment of annatto; studied for antioxidant and potential photoprotective properties. Widely used as a natural food colourant with an established safety profile.
POLYTERPENES
Natural RubberPolyisoprene; cis-1,4-Polyisoprene; LatexTerpenoid (Polyterpene)Rubber TreeHevea brasiliensisLatex (Sap)9006-04-6EmergingA high-molecular-weight polyterpene of industrial importance; helps the tree seal wounds by rapid coagulation. Its protein content is the source of latex allergy in sensitised individuals.
Gutta-Perchatrans-Polyisoprene; Dental polymerTerpenoid (Polyterpene)Gutta-Percha TreePalaquium guttaBark / Leaves9000-30-0HighThe trans-isomer of natural rubber; used clinically as the standard material for endodontic root canal obturation due to its biocompatibility, flexibility, and sealing properties.
ChicleNatural chewing gum base; Sapodilla latexTerpenoid (Polyterpene)SapodillaManilkara zapotaLatex (Sap)9000-40-2ModerateA polyterpene latex traditionally used as the original chewing gum base; biocompatible and biodegradable, with renewed interest as a natural alternative to synthetic gum bases.
Balatatrans-Polyisoprene; Bulletwood latexTerpenoid (Polyterpene)BulletwoodManilkara bidentataLatex (Sap)9006-04-6EmergingA durable polyterpene historically used for golf ball covers, submarine cable insulation, and industrial belting; studied for biocompatible polymer applications.
ALIPHATIC GLUCOSINOLATES
Glucoraphanin4-Methylsulfinylbutyl glucosinolate; GRNGlucosinolate (Aliphatic)BroccoliBrassica oleraceaFloret / Seedling20830-75-5HighThe primary glucosinolate of broccoli; enzymatically hydrolysed to sulforaphane by myrosinase on cell disruption. Well-supported by clinical evidence for Nrf2 pathway activation and detoxification enzyme induction.
Sinigrin2-Propenyl glucosinolate; Allyl glucosinolateGlucosinolate (Aliphatic)Black MustardBrassica nigraSeed3952-98-9ModerateHydrolysed by myrosinase to allyl isothiocyanate, the primary pungent compound of black mustard; studied for antimicrobial, anti-inflammatory, and potential chemopreventive properties.
Glucoerucin4-Methylthiobutyl glucosinolate; GERGlucosinolate (Aliphatic)Arugula (Rocket)Eruca vesicariaLeaf / Seed21956-27-6ModerateHydrolysed to erucin, a sulforaphane analogue; studied for antioxidant, anti-inflammatory, and cardiovascular-supportive properties. A major glucosinolate of arugula leaves.
Progoitrin(2R)-2-Hydroxy-3-butenyl glucosinolateGlucosinolate (Aliphatic)RapeseedBrassica napusSeed / Leaf585-95-5ModerateHydrolysed to goitrin, which may inhibit thyroid hormone synthesis at high intake levels; regulated in rapeseed food products. At moderate dietary intake from whole vegetables, risk is generally low.
Gluconapin3-Butenyl glucosinolate; GNAGlucosinolate (Aliphatic)Turnip RapeBrassica rapaSeed / Leaf19253-97-5ModerateHydrolysed to 3-butenyl isothiocyanate; studied for induction of liver phase-II detoxification enzymes supporting healthy xenobiotic metabolism.
Glucobrassicanapin4-Pentenyl glucosinolate; GBNGlucosinolate (Aliphatic)Bok ChoyBrassica rapaLeaf21292-36-4ModerateHydrolysed to 4-pentenyl isothiocyanate; contributes to the overall glucosinolate-derived detoxification support of Brassica vegetable consumption.
Glucoiberin3-Methylsulfinylpropyl glucosinolate; GIBGlucosinolate (Aliphatic)Broccoli / KaleBrassica oleraceaLeaf / Floret534-48-5ModerateHydrolysed to iberin, a sulforaphane congener; studied for Phase-II enzyme-inducing and antioxidant properties contributing to the health benefits of Brassica vegetables.
Glucoraphenin4-Methylsulfinyl-3-butenyl glucosinolate; GREGlucosinolate (Aliphatic)RadishRaphanus sativusRoot26041-78-7ModerateHydrolysed to raphanin; studied for antimicrobial, hepatoprotective, and choleretic properties consistent with the traditional use of radish for liver and gallbladder support.
Glucoalyssin5-Methylsulfinylpentyl glucosinolateGlucosinolate (Aliphatic)Sweet AlyssumLobularia maritimaFlower / LeafEmergingA C5 methylsulfinyl glucosinolate studied for antioxidant and antimicrobial properties in early-stage research; contributes to the glucosinolate diversity of the Brassicaceae family.
Glucocheirolin3-Methylsulfonylpropyl glucosinolateGlucosinolate (Aliphatic)Wallflower / ArugulaCheiranthus cheiriFlower / LeafEmergingA sulfonyl-type aliphatic glucosinolate; studied for cardiovascular and antimicrobial properties as part of the Brassica glucosinolate profile.
GlucocapparinMethyl glucosinolate; Caper glucosinolateGlucosinolate (Aliphatic)CaperCapparis spinosaFlower Bud / Root13433-89-1ModerateThe simplest aliphatic glucosinolate; hydrolysed to methyl isothiocyanate. Studied for hepatoprotective and neuroprotective properties consistent with the traditional Mediterranean use of capers.
Glucoputranjivin(R)-1-Methylethyl glucosinolateGlucosinolate (Aliphatic)PutranjivaPutranjiva roxburghiiLeaf / SeedModerateAn isopropyl glucosinolate studied for anti-inflammatory and antipyretic properties in traditional Ayurvedic medicine contexts.
Glucoiberverin3-Methylthiopropyl glucosinolate; GIVGlucosinolate (Aliphatic)CandytuftIberis amaraSeed / LeafModerateHydrolysed to iberverin; studied for smooth muscle relaxant and antiallergic properties relevant to the traditional digestive use of candytuft preparations.
Glucoberteroin5-Methylthiopentyl glucosinolateGlucosinolate (Aliphatic)Hoary AlyssumBerteroa incanaSeedEmergingA C5 methylthio glucosinolate studied as a botanical pest deterrent; contributes to the structural diversity of the aliphatic glucosinolate sub-class.
Glucocochlearin(S)-1-Methylpropyl glucosinolateGlucosinolate (Aliphatic)Scurvy-grassCochlearia officinalisLeafModerateHydrolysed to a branched-chain isothiocyanate; contributes to the antiscorbutic and antioxidant properties historically attributed to scurvy-grass in traditional seafarer medicine.
Gluconapoleiferin2-Hydroxy-4-pentenyl glucosinolate; GNLGlucosinolate (Aliphatic)RutabagaBrassica napusRoot / Leaf21292-37-5ModerateA hydroxy-alkenyl glucosinolate studied for contributions to healthy blood glucose balance and liver detoxification enzyme support.
Epiprogoitrin(2S)-2-Hydroxy-3-butenyl glucosinolateGlucosinolate (Aliphatic)CrambeCrambe abyssinicaSeedEmergingThe (2S) epimer of progoitrin; studied for plant stress defence roles and as a potential biocontrol compound. Monitored for thyroid-related considerations at high intake.
Dehydroerucin4-Methylthio-3-butenyl glucosinolate; DHEGlucosinolate (Aliphatic)Daikon RadishRaphanus sativusRootEmergingA desaturated glucoerucin congener; studied for antioxidant properties and potential support for respiratory airway clearance.
INDOLIC GLUCOSINOLATES
Glucobrassicin3-Indolylmethyl glucosinolate; I3G; GBSGlucosinolate (Indolic)Brussels SproutsBrassica oleraceaBuds (Sprouts)4356-52-9HighThe most abundant indolic glucosinolate in Brassica vegetables; hydrolysed to indole-3-carbinol (I3C) and subsequently diindolylmethane (DIM), both well-studied for hormone metabolism and chemopreventive support.
4-Hydroxyglucobrassicin4-Hydroxy-I3G; 4-OH-GBSGlucosinolate (Indolic)CabbageBrassica oleraceaLeafModerateHydrolysed to 4-hydroxyindole-3-carbinol; studied for hormonal balance and tissue repair support as part of the indolic glucosinolate family in cabbage.
4-Methoxyglucobrassicin4-Methoxy-I3G; 4-MeO-GBS; NeoglucobrassicinGlucosinolate (Indolic)BroccoliBrassica oleraceaFloretModerateHydrolysed to 4-methoxyindole-3-carbinol; studied for immunomodulatory properties and potential support for healthy cellular surveillance mechanisms.
Neoglucobrassicin1-Methoxy-I3G; N-MeO-GBSGlucosinolate (Indolic)CauliflowerBrassica oleraceaFloret19253-97-5ModerateThe N-methoxy derivative of glucobrassicin; studied for anti-inflammatory properties and detoxification pathway activation as part of the Brassica indolic glucosinolate complex.
Glucobrassicin-1-sulfonate1-Sulfo-I3G; Woad indolic GSLGlucosinolate (Indolic)WoadIsatis tinctoriaRoot / LeafModerateFound in woad root, a traditional European blue dye plant; studied for antimicrobial and immunomodulatory properties consistent with the use of Isatis root in traditional Chinese medicine.
AROMATIC GLUCOSINOLATES
Gluconasturtiin2-Phenylethyl glucosinolate; PEITC precursorGlucosinolate (Aromatic)WatercressNasturtium officinaleLeaf / Stem499-30-9HighHydrolysed to phenethyl isothiocyanate (PEITC); well-studied for Nrf2-activating, DNA-protective, and chemopreventive properties with multiple human bioavailability and intervention trials.
GlucotropaeolinBenzyl glucosinolate; BITC precursorGlucosinolate (Aromatic)Garden CressLepidium sativumSeed / Leaf1119-34-2ModerateHydrolysed to benzyl isothiocyanate (BITC); studied for antimicrobial, hepatoprotective, and potential antiproliferative properties. A primary glucosinolate of nasturtium and garden cress.
Sinalbin4-Hydroxybenzyl glucosinolate; White Mustard GSLGlucosinolate (Aromatic)White MustardSinapis albaSeed3952-98-9ModerateHydrolysed to 4-hydroxybenzyl isothiocyanate, which provides a milder heat than allyl isothiocyanate; studied for antimicrobial and respiratory health-supportive properties.
Glucomoringin4-alpha-L-Rhamnosyloxy-benzyl GSL; GMGGlucosinolate (Aromatic)MoringaMoringa oleiferaLeaf / SeedModerateThe unique glucosinolate of Moringa; hydrolysed by plant myrosinase to the isothiocyanate MIC-1, studied for anti-inflammatory, antioxidant, and immunomodulatory properties.
Glucobarbarin(S)-2-Hydroxy-2-phenylethyl glucosinolateGlucosinolate (Aromatic)Winter CressBarbarea vulgarisLeaf / SeedModerateA hydroxylated aromatic glucosinolate; studied for urinary tract health support and as a marker compound for winter cress. Contributes to insect herbivory resistance.
GlucolepigraminIndanyl glucosinolateGlucosinolate (Aromatic)PepperweedLepidium graminifoliumAerial PartsEmergingA cyclopropane-containing aromatic glucosinolate; studied for antioxidant and antimicrobial properties in early-stage research.
Glucosinojnain4-(alpha-L-Rhamnosyloxy)benzyl GSL; Moringa variantGlucosinolate (Aromatic)MoringaMoringa stenopetalaSeed / LeafModerateA rhamnosyloxy-benzyl glucosinolate from East African Moringa species; studied for anti-inflammatory and circulatory health-supportive properties.
GLUCOSINOLATE HYDROLYSIS PRODUCTS (BIOACTIVE BREAKDOWN COMPOUNDS)
Sulforaphane1-Isothiocyanato-4-(methylsulfinyl)butane; SFN; SFGlucosinolate Hydrolysis Product (Isothiocyanate)BroccoliBrassica oleraceaSprouts / Florets4478-93-7ModerateThe hydrolysis product of glucoraphanin; well-studied for Nrf2 pathway activation and Phase-II detoxification enzyme induction. Requires intact myrosinase activity or gut microbiota for formation from supplements.
Indole-3-CarbinolI3C; Glucobrassicin hydrolysis productGlucosinolate Hydrolysis Product (Indole)Broccoli / CabbageBrassica oleraceaFloret / Leaf700-06-1ModerateThe primary hydrolysis product of glucobrassicin; studied for oestrogen metabolism modulation and potential chemopreventive activity. Converts to DIM in the stomach.
DiindolylmethaneDIM; 3,3'-Diindolylmethane; I3C condensation productGlucosinolate Hydrolysis Product (Indole)Broccoli / CruciferousBrassica oleraceaFloret / Leaf1968-05-4ModerateFormed from I3C condensation in the acid environment of the stomach; studied for oestrogen receptor modulation and potential support for hormonal balance and immune function.
Phenethyl IsothiocyanatePEITC; Gluconasturtiin hydrolysis productGlucosinolate Hydrolysis Product (Isothiocyanate)WatercressNasturtium officinaleLeaf / Stem2257-09-2ModerateThe isothiocyanate from gluconasturtiin hydrolysis; studied for glutathione induction, detoxification support, and potential antiproliferative effects with human bioavailability data available.
Allyl IsothiocyanateAITC; Sinigrin hydrolysis product; Mustard oilGlucosinolate Hydrolysis Product (Isothiocyanate)Black MustardBrassica nigraSeed57-06-7ModerateThe primary hydrolysis product of sinigrin; responsible for the pungency of mustard and wasabi. Studied for antimicrobial, anti-inflammatory, and potential neuroprotective properties.
Iberin3-Methylsulfinylpropyl isothiocyanate; Glucoiberin productGlucosinolate Hydrolysis Product (Isothiocyanate)Kale / BroccoliBrassica oleraceaLeafModerateThe isothiocyanate derived from glucoiberin; studied for Phase-II enzyme-inducing and antioxidant properties contributing to the health value of diverse Brassica vegetable consumption.
Erucin4-Methylthiobutyl isothiocyanate; Glucoerucin productGlucosinolate Hydrolysis Product (Isothiocyanate)ArugulaEruca vesicariaLeaf4430-36-8ModerateThe sulphide analogue of sulforaphane formed from glucoerucin hydrolysis; studied for comparable Nrf2-activating and antioxidant properties to sulforaphane, with similar bioavailability.
ORGANOSULFUR COMPOUNDS (ALLIUM-DERIVED)
AllicinDiallyl thiosulfinate; Allium bioactiveOrganosulfur (Thiosulfinate)GarlicAllium sativumBulb539-86-6ModerateFormed from alliin by alliinase when garlic tissue is disrupted; studied for antimicrobial, cardiovascular-supportive, and cholesterol-modulating properties. Unstable compound — activity diminishes rapidly with cooking or processing.
AlliinS-Allyl-L-cysteine sulfoxide; Garlic precursorOrganosulfur (Cysteine Sulfoxide)GarlicAllium sativumBulb556-27-4ModerateThe stable precursor to allicin in intact garlic cloves; studied for its own mild cardiovascular and antioxidant properties independent of allicin conversion.
S-AllylcysteineSAC; Aged Garlic primary activeOrganosulfur (Cysteine Derivative)Aged GarlicAllium sativumBulb (Aged Extract)37921-38-3ModerateThe primary bioactive of aged garlic extract; water-soluble and highly bioavailable. Studied for neuroprotective, cardiovascular, and antioxidant properties with good human pharmacokinetic data.
S-AllylmercaptocysteineSAMC; Aged Garlic organosulfurOrganosulfur (Cysteine Derivative)Aged GarlicAllium sativumBulb (Aged Extract)ModerateA stable water-soluble garlic organosulfur compound studied for potential antiproliferative and hepatoprotective properties alongside SAC in aged garlic preparations.
Diallyl DisulfideDADS; Garlic oil constituentOrganosulfur (Polysulfide)GarlicAllium sativumBulb2179-57-9ModerateA volatile garlic organosulfur compound formed from allicin; studied for antimicrobial, antifungal, and Phase-II enzyme-inducing properties. Responsible for much of the characteristic garlic odour.
Diallyl TrisulfideDATS; Garlic oil polysulfideOrganosulfur (Polysulfide)GarlicAllium sativumBulb2050-87-5ModerateStudied for hydrogen sulfide-generating properties and potential cardioprotective effects via smooth muscle relaxation and vasodilation; the most bioactive of the garlic diallyl polysulfides in preclinical research.
Ajoene(E,Z)-4,5,9-Trithiadodeca-1,6,11-triene 9-oxideOrganosulfur (Vinyldithiin)GarlicAllium sativumBulb92285-61-5ModerateStudied for antiplatelet, antifungal, and potential antiproliferative properties; formed from allicin in aged oil macerates of garlic.
Allyl Methyl DisulfideAMDS; Garlic breath compoundOrganosulfur (Polysulfide)GarlicAllium sativumBulb2179-58-0EmergingA volatile garlic metabolite contributing to characteristic garlic breath; studied as a marker for garlic organosulfur bioavailability and gut microbial metabolism.
Propyl DisulfideDi-1-propenyl disulfide; Onion organosulfurOrganosulfur (Polysulfide)OnionAllium cepaBulb629-19-6ModerateA primary organosulfur compound of onion; studied for antithrombotic and mild antimicrobial properties. Associated with Heinz body haemolytic anaemia in dogs — not a concern at normal human dietary intake.
CepaenesThiosulfinate esters; Onion tear-factor relatedOrganosulfur (Thiosulfinate)OnionAllium cepaBulbModerateA family of thiosulfinate compounds unique to onion; studied for antiplatelet, anti-inflammatory, and antiasthmatic properties. Thermolabile — activity is reduced by cooking.
IsoalliinS-(1-Propenyl)-L-cysteine sulfoxide; Onion lachrymatory precursorOrganosulfur (Cysteine Sulfoxide)OnionAllium cepaBulb17795-80-1ModerateThe primary cysteine sulfoxide of onion; the precursor to propanethial S-oxide (the lachrymatory factor or tear compound) formed on enzymatic hydrolysis. Studied for antioxidant and antimicrobial properties.
MethiinS-Methyl-L-cysteine sulfoxide; Brassica organosulfurOrganosulfur (Cysteine Sulfoxide)CabbageBrassica oleraceaLeaf3108-60-9ModerateA cysteine sulfoxide found in cabbage and other Brassica vegetables; studied for antioxidant and potential hepatoprotective properties as a stable dietary organosulfur source.
Sinigrin Derived AITCAllyl isothiocyanate; Wasabi / Horseradish pungencyOrganosulfur (Isothiocyanate)Horseradish / WasabiArmoracia rusticana / Wasabia japonicaRoot57-06-7ModerateThe primary pungency compound of wasabi and horseradish; studied for antimicrobial, anti-inflammatory, and gastric health-supporting properties. Activates TRPA1 channels to produce the characteristic burning sensation.
OTHER NITROGEN-CONTAINING SECONDARY METABOLITES
Piperine1-Piperoylpiperidine; Black Pepper amideAlkaloid-related (Amide)Black PepperPiper nigrumDried Fruits94-62-2HighA well-documented bioavailability enhancer; inhibits CYP3A4 and P-glycoprotein to significantly increase absorption of co-administered bioactives including curcumin and resveratrol.
Capsaicin8-Methyl-N-vanillyl-6-nonenamide; VanilloidVanilloid (Capsaicinoid)Chili PepperCapsicum frutescensFruit404-86-4HighA TRPV1 receptor agonist with well-documented topical analgesic applications; supported by clinical evidence for localised neuropathic and musculoskeletal pain management.
Gingerol[6]-Gingerol; Ginger pungent compoundPhenylpropanoid-related (Shogaol precursor)GingerZingiber officinaleRhizome23513-14-6HighThe primary pungency compound of fresh ginger; studied extensively for antiemetic, anti-inflammatory, and gastrointestinal comfort-supportive properties. Multiple human trials support its use for nausea management.
Shogaol[6]-Shogaol; Dehydration product of gingerolPhenylpropanoid-relatedDried GingerZingiber officinaleRhizome (Dried)555-66-8ModerateFormed from gingerol during drying and cooking of ginger; studied for potent anti-inflammatory and potential neuroprotective properties with higher TRPV1 activity than gingerol.
ZingeroneVanillylacetone; Cooked ginger aromaticPhenylpropanoid-relatedCooked GingerZingiber officinaleRhizome (Cooked)122-48-5ModerateFormed from gingerol during cooking; studied for anti-inflammatory, antioxidant, and gut health-supportive properties. Contributes to the characteristic aroma of cooked ginger preparations.
Cyanogenic GlycosidesAmygdalin / Prunasin / Dhurrin (class)Cyanogenic GlycosideBitter Almond / SorghumPrunus amygdalus / Sorghum bicolorSeed / Leaf29883-15-6ModerateA class of plant defence glycosides hydrolysed to toxic hydrogen cyanide on tissue damage; associated with acute toxicity at high intake. Present at low regulated levels in food-grade bitter almond, cassava, and stone fruit kernels.
AmygdalinD-Mandelonitrile gentiobioside; Laetrile precursorCyanogenic GlycosideBitter AlmondPrunus amygdalusSeed Kernel29883-15-6EmergingA cyanogenic diglycoside that releases hydrogen cyanide on hydrolysis; associated with fatal cyanide poisoning from excessive intake of bitter almond kernels or apricot seeds. Documented for safety reference — not therapeutic.
DhurrinL-Tyrosine-derived CG; Sorghum toxinCyanogenic GlycosideSorghumSorghum bicolorSeedling / Leaf499-20-7EmergingA cyanogenic glycoside that protects young sorghum plants from herbivores; degrades to lower levels in mature grain. Monitored in food sorghum products for cyanide-related safety.
LinamarinAcetone cyanohydrin glucoside; Cassava CGCyanogenic GlycosideCassavaManihot esculentaRoot554-35-8ModerateThe primary cyanogenic glycoside of cassava; potentially toxic if cassava is insufficiently processed. Traditional and industrial processing methods (soaking, fermentation, drying) effectively reduce levels to safe dietary thresholds.