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Active Compound Index

A molecular-level reference for every bioactive compound in the botanical kingdom

The Active Compound Index is the molecular backbone of the HerbIQ framework. Where the four pillars explain how plant chemistry is sourced, extracted, formulated, and absorbed, this index answers the prior question: what exactly is in a plant, and what does science currently know about what it does? Every entry is a fixed scientific reference — not a health claim, but a structured record linking a molecule to its source biology, chemical identity, and the honest weight of available evidence.

The index is divided into two tables. Primary Metabolites are the cellular infrastructure — carbohydrates, lipids, proteins, vitamins and minerals every living plant cell requires. Secondary Metabolites are the bioactive signals — alkaloids, polyphenols, terpenoids, and glucosinolates responsible for the majority of pharmacologically interesting activity in botanical ingredients.

570+
Secondary
Metabolites
400+
Primary
Metabolites
16
Compound
Classes
7
Data Fields
per Entry

Conservative, hedged language throughout — "studied for", "may support", "associated with". No entry makes a disease treatment claim. The badge reflects weight of evidence, not regulatory approval.

HighMultiple human RCTs or clinical consensus ModerateLimited human trials or strong mechanistic data EmergingPrimarily early-stage lab or in vitro research

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// PRIMARY METABOLITES: CELLULAR INFRASTRUCTURE
Compound Also Known As Class (Sub-class) Botanical Source Plant Part Claim Strength Primary Biological Action
MONOSACCHARIDES
D-GlucoseCAS 50-99-7Dextrose; Blood Sugar; Corn SugarCarbohydrates (Sugar / Monosaccharide)Sugar CaneSaccharum officinarumStemHighThe fundamental source of fast-acting fuel for the human brain and muscle tissues.
D-FructoseCAS 57-48-7Levulose; Fruit SugarCarbohydrates (Sugar / Monosaccharide)AppleMalus domesticaFruitModerateA natural sweetener that provides energy with a lower immediate insulin spike than glucose alone.
D-GalactoseCAS 59-23-4Brain Sugar; CerebroseCarbohydrates (Sugar / Monosaccharide)SoybeanGlycine maxSeedModerateSupports the health of human nerve cells and is a component of healthy cell-to-cell communication.
D-MannoseCAS 3458-28-4—Carbohydrates (Sugar / Monosaccharide)Guar BeanCyamopsis tetragonolobaSeedHighWidely used to support urinary tract health by preventing harmful bacteria from adhering to the bladder wall.
D-XyloseCAS 58-86-6Wood Sugar; Birch SugarCarbohydrates (Sugar / Monosaccharide)Birch TreeBetula spp.WoodModerateA low-calorie sugar used in wellness products to support healthy gut fermentation.
L-ArabinoseCAS 5328-37-0Pectin Sugar; Gum SugarCarbohydrates (Sugar / Monosaccharide)Sugar BeetBeta vulgarisRootModerateHelps manage blood sugar by inhibiting the enzyme that breaks down sucrose in the small intestine.
D-RiboseCAS 50-69-1—Carbohydrates (Sugar / Monosaccharide)All PlantsEvery CellModerateSupports heart health and athletic recovery by helping the body replenish its cellular energy (ATP) reserves.
2-Deoxy-D-riboseCAS 533-67-5Deoxyribose; DNA SugarCarbohydrates (Sugar / Monosaccharide)All PlantsNucleusHighThe essential sugar found in every human cell that forms the backbone of our entire genetic code (DNA).
GlyceraldehydeCAS 56-82-6D-Glyceraldehyde; GlyceralCarbohydrates (Sugar / Monosaccharide)SpinachSpinacia oleraceaChloroplastEmergingA metabolic intermediate that researchers study to understand how humans process and convert dietary sugars.
DihydroxyacetoneCAS 96-26-4DHA; GlyceroneCarbohydrates (Sugar / Monosaccharide)SpinachSpinacia oleraceaChloroplastModerateStudied for its role in cellular metabolism and widely used in topical wellness products for skin-toning.
D-ErythroseCAS 583-50-6—Carbohydrates (Sugar / Monosaccharide)Various PlantsLeavesEmergingA precursor for essential aromatic amino acids that must be obtained through a plant-rich diet.
D-ThreoseCAS 95-43-2—Carbohydrates (Sugar / Monosaccharide)Various PlantsLeavesEmergingA rare four-carbon sugar that serves as a biochemical research tool for studying carbohydrate metabolism.
D-RibuloseCAS 488-84-6D-Erythro-2-pentuloseCarbohydrates (Sugar / Monosaccharide)All PlantsChloroplastEmergingA foundational photosynthetic molecule in the plants we eat, enabling them to convert CO₂ into food.
D-XyluloseCAS 551-84-8D-threo-2-PentuloseCarbohydrates (Sugar / Monosaccharide)Various PlantsLeavesEmergingSupports the efficient recycling of carbon through key pentose phosphate metabolic pathways.
D-SedoheptuloseSedoheptuloseCarbohydrates (Sugar / Monosaccharide)StonecropSedum spectabileLeavesEmergingMay help regulate human energy metabolism; being studied for potential anti-diabetic properties.
Mannoheptulose—Carbohydrates (Sugar / Monosaccharide)AvocadoPersea americanaFruitEmergingMay help modulate insulin secretion; studied for potential weight management and caloric restriction benefits.
D-AlloseCAS 2595-97-3—Carbohydrates (Sugar / Monosaccharide)Protea ShrubProtea rubropilosaLeavesEmergingA rare sugar with documented anti-inflammatory and early-stage anticancer properties in laboratory studies.
D-Altrose—Carbohydrates (Sugar / Monosaccharide)Rare VarietiesVariousEmergingA rare sugar used in medical research to develop new antimicrobial treatment strategies.
D-Gulose—Carbohydrates (Sugar / Monosaccharide)Various PlantsVariousEmergingA glucose isomer used as a research marker for studying sugar transport mechanisms in human cells.
L-Idose—Carbohydrates (Sugar / Monosaccharide)Various PlantsVariousEmergingA trace sugar used to understand the complex fiber structures in dietary plants that promote gut health.
D-Talose—Carbohydrates (Sugar / Monosaccharide)Various PlantsVariousEmergingSupports biochemical research into how human cells recognize and bind to different sugar configurations.
D-Psicose (Allulose)CAS 551-68-8Allulose; D-Allulose; Rare SugarCarbohydrates (Sugar / Monosaccharide)WheatTriticum aestivumGrainsModerateA low-calorie sweetener that does not raise blood sugar and may help reduce visceral fat accumulation.
L-SorboseCAS 87-79-6—Carbohydrates (Sugar / Monosaccharide)Mountain AshSorbus aucupariaBerriesEmergingA rare industrial-route precursor used in Vitamin C manufacturing; studied for its own low-glycemic properties.
D-TagatoseCAS 87-81-0—Carbohydrates (Sugar / Monosaccharide)Sterculia GumSterculia urensExudateModerateA prebiotic sugar that supports healthy weight and dental wellness without promoting tooth decay.
L-FucoseCAS 2438-80-46-Deoxy-L-galactoseCarbohydrates (Sugar / Monosaccharide)RockcressArabidopsis thalianaCell WallModerateEssential for human gut epithelial health and supports a strong, balanced innate immune response.
L-RhamnoseCAS 3615-41-66-Deoxy-L-mannose; IsodulcitCarbohydrates (Sugar / Monosaccharide)BuckthornRhamnus spp.BarkModerateA component of complex dietary fibers that helps maintain a resilient and healthy gut lining.
D-Apiose—Carbohydrates (Sugar / Monosaccharide)ParsleyPetroselinum crispumLeavesEmergingA rare branched-chain sugar found in plant cell walls; studied for potential anti-inflammatory benefits.
L-Aceric Acid—Carbohydrates (Sugar / Monosaccharide)SycamoreAcer pseudoplatanusCell WallEmergingA unique sugar component of complex dietary fibers; helps support a diverse and healthy gut microbiome.
D-Galacturonic AcidCAS 685-73-4Pectin Acid; GalACarbohydrates (Sugar / Monosaccharide)LemonCitrus limonPeelModerateThe primary structural unit of pectin, which binds dietary cholesterol and helps lower blood levels.
D-Glucuronic AcidCAS 6556-12-3GlcACarbohydrates (Sugar / Monosaccharide)Gum ArabicAcacia senegalSapModerateAids the body’s natural detoxification processes and supports connective tissue and joint health.
Kdo (Octulosonic Acid)3-Deoxy-D-manno-octulosonic acid; KDOCarbohydrates (Sugar / Monosaccharide)All PlantsCell WallEmergingUsed in research to understand how beneficial gut bacteria interact with the human intestinal wall.
Dha (Heptulosaric Acid)3-Deoxy-D-lyxo-heptulosaric acidCarbohydrates (Sugar / Monosaccharide)MossesPhyscomitrella patensCell WallEmergingA trace sugar component that contributes to the structural diversity of dietary plant cell-wall fiber.
NUCLEOTIDE SUGARS & PHOSPHORYLATED FORMS
D-Glucose-6-PhosphateG6P; Glucose-6-phosphate; Robison EsterCarbohydrates (Sugar / Monosaccharide)All PlantsEvery CellHighA vital metabolic intermediate through which cells convert dietary sugar into the energy used for all life functions.
Fructose-1,6-BisphosphateF1,6BP; Harden-Young EsterCarbohydrates (Sugar / Monosaccharide)All PlantsEvery CellHighA high-energy glycolytic intermediate that keeps cellular metabolism running efficiently during physical exercise.
UDP-GlucoseUridine Diphosphoglucose; UDPGCarbohydrates (Sugar / Monosaccharide)All PlantsEvery CellModerateThe activated sugar donor form used to build essential glycoproteins that support immune system function.
GDP-MannoseGuanosine Diphosphate MannoseCarbohydrates (Sugar / Monosaccharide)All PlantsEvery CellModerateFundamental for building cell-surface proteins that help the immune system distinguish self from pathogen.
UDP-Galacturonic AcidUDP-GalACarbohydrates (Sugar / Monosaccharide)All PlantsEvery CellEmergingStudied by researchers to understand how plant fiber structures are built, informing improved fiber supplements.
ADP-GlucoseAdenosine DiphosphoglucoseCarbohydrates (Sugar / Monosaccharide)All PlantsPlastidModerateThe key activated donor for all plant starch biosynthesis; determines whether a food acts as a fast or slow carb.
Quinovose6-DeoxyglucoseCarbohydrates (Sugar / Monosaccharide)All Higher PlantsChloroplastEmergingA crucial component of plant chloroplast membrane lipids that help maintain healthy human cell membrane fluidity.
AMINO SUGARS
GlucosamineCAS 3416-24-82-Amino-2-deoxy-D-glucose; GlcN; ChitosamineCarbohydrates (Sugar / Monosaccharide)Neem TreeAzadirachta indicaSapHighOne of the most extensively validated supplements for protecting joint cartilage and reducing arthritis-related pain.
GalactosamineCAS 7535-00-42-Amino-2-deoxy-D-galactose; GalN; ChondrosamineCarbohydrates (Sugar / Monosaccharide)Various PlantsVariousModerateSupports the structural health of joints, tendons, and heart valves as a key amino sugar building unit.
Mannosamine2-Amino-2-deoxy-D-mannose; ManNCarbohydrates (Sugar / Monosaccharide)Various PlantsVariousEmergingUsed in research to develop new treatments for rare metabolic and immune-related disorders.
Rhamnosamine2-Amino-2-deoxy-L-rhamnoseCarbohydrates (Sugar / Monosaccharide)Various PlantsVariousEmergingA rare amino sugar studied for its role in healthy signaling of human intestinal epithelial cells.
Quinovosamine2-Amino-2-deoxy-D-quinovoseCarbohydrates (Sugar / Monosaccharide)Various PlantsVariousEmergingServes as a biochemical marker in laboratory tests for detecting and monitoring healthy cellular development.
DEOXYGENATED SUGARS
Abequose3,6-Dideoxy-D-galactoseCarbohydrates (Sugar / Monosaccharide)Rare VarietiesVariousEmergingStudied for its ability to help beneficial gut bacteria identify and colonize the human intestinal environment.
Tyvelose3,6-Dideoxy-D-arabino-hexoseCarbohydrates (Sugar / Monosaccharide)Various PlantsVariousEmergingA specialized surface sugar used to understand how the immune system recognizes and combats parasites.
Ascarylose3,6-Dideoxy-L-arabino-hexoseCarbohydrates (Sugar / Monosaccharide)Various PlantsVariousEmergingA trace sugar from rare plants used to study how human cells adapt to different environmental stresses.
Olivose2,6-Dideoxy-D-arabino-hexoseCarbohydrates (Sugar / Monosaccharide)Various PlantsVariousEmergingFound in natural plant antibiotics that protect against harmful bacterial overgrowth in the human body.
Amicetose2,3,6-Trideoxy-D-mannoseCarbohydrates (Sugar / Monosaccharide)Various PlantsVariousEmergingContributes to the diversity of plant-derived deoxy sugars that support cellular defense mechanisms.
DISACCHARIDES
SucroseCAS 57-50-1Table Sugar; Cane Sugar; Beet SugarCarbohydrates (Sugar / Disaccharide)Sugar BeetBeta vulgarisRootHighA dual-energy source (glucose + fructose) that should be consumed in moderation to support metabolic health.
MaltoseCAS 69-79-4Malt Sugar; MaltobioseCarbohydrates (Sugar / Disaccharide)BarleyHordeum vulgareGrainsHighProvides a readily digestible, steady energy supply that supports physical activity and endurance.
TrehaloseCAS 99-20-7Mycose; Tremalose; Mushroom SugarCarbohydrates (Sugar / Disaccharide)Resurrection PlantSelaginella lepidophyllaWhole PlantModerateProtects human cells from dehydration and oxidative stress; studied for neuroprotective and anti-aging benefits.
CellobioseCAS 528-50-74-O-β-D-Glucopyranosyl-D-glucoseCarbohydrates (Sugar / Disaccharide)CottonGossypium hirsutumFiberModerateActs as insoluble dietary roughage that helps maintain regularity and supports healthy colon function.
GentiobioseCAS 554-91-6—Carbohydrates (Sugar / Disaccharide)GentianGentiana luteaRootModerateFound in bitter digestive tonics that stimulate healthy bile flow, enzyme secretion, and appetite.
Turanose3-O-α-D-Glucopyranosyl-D-fructoseCarbohydrates (Sugar / Disaccharide)Various NectarsFlowersEmergingA low-glycemic nectar disaccharide that provides a slower, more sustained energy release than table sugar.
Isomaltose6-O-α-D-Glucopyranosyl-D-glucoseCarbohydrates (Sugar / Disaccharide)CornZea maysGrainsModerateA branched-chain disaccharide produced during slow starch digestion; supports a more balanced blood sugar response.
IsomaltuloseCAS 13718-94-0PalatinoseCarbohydrates (Sugar / Disaccharide)Sugar CaneSaccharum officinarumSapHighA tooth-friendly sugar that releases energy slowly over several hours, avoiding the typical blood sugar spike.
SophoroseCAS 6035-43-42-O-β-D-Glucopyranosyl-D-glucoseCarbohydrates (Sugar / Disaccharide)Sophora TreeStyphnolobium japonicumFruitEmergingStudied for its potential to boost the effectiveness of specific immune-supporting bioactive plant compounds.
Laminaribiose3-O-β-D-Glucopyranosyl-D-glucoseCarbohydrates (Sugar / Disaccharide)BarleyHordeum vulgareGrainsModerateFormed during the enzymatic breakdown of heart-healthy cereal β-glucan fiber; supports gut microflora.
Kojibiose2-O-α-D-Glucopyranosyl-D-glucoseCarbohydrates (Sugar / Disaccharide)CloverTrifolium spp.NectarEmergingA rare prebiotic disaccharide found in certain honeys; supports healthy gut microbial balance.
Nigerose3-O-α-D-Glucopyranosyl-D-glucoseCarbohydrates (Sugar / Disaccharide)BuckwheatFagopyrum esculentumSeedEmergingContributes to the immune-modulating properties found in certain traditional fermented plant-based foods.
MelibioseCAS 585-99-96-O-α-D-Galactopyranosyl-D-glucoseCarbohydrates (Sugar / Disaccharide)SoybeansGlycine maxSeedModerateA prebiotic disaccharide that helps increase the population of beneficial bifidobacteria in the colon.
Rutinose6-O-α-L-Rhamnosyl-D-glucoseCarbohydrates (Sugar / Disaccharide)BuckwheatFagopyrum esculentumLeavesModerateThe sugar carrier of rutin and related antioxidants that protect blood vessels and support circulation.
Neohesperidose2-O-α-L-Rhamnosyl-D-glucoseCarbohydrates (Sugar / Disaccharide)Bitter OrangeCitrus aurantiumFruit PeelModerateContributes to the digestion-stimulating and appetite-regulating effects of bitter citrus peel extracts.
Vicianose6-O-α-L-Arabinosyl-D-glucoseCarbohydrates (Sugar / Disaccharide)VetchVicia spp.SeedsEmergingFound in legumes as the sugar carrier for plant glycoside compounds; contributes to mild antioxidant activity.
Primeverose6-O-β-D-Xylopyranosyl-D-glucoseCarbohydrates (Sugar / Disaccharide)PrimrosePrimula spp.RootsEmergingProvides the sugar carrier for aromatic plant aglycones widely used in herbal wellness and aromatherapy.
Robinobiose6-O-α-L-Rhamnosyl-D-galactoseCarbohydrates (Sugar / Disaccharide)Locust TreeRobinia pseudoacaciaFlowersEmergingA specialized carrier sugar that transports health-relevant plant flavonoid compounds into the body.
Scillabiose—Carbohydrates (Sugar / Disaccharide)SquillDrimia maritimaBulbEmergingHistorically used in heart-related wellness preparations to support healthy circulatory function.
Strophanthobiose—Carbohydrates (Sugar / Disaccharide)StrophanthusStrophanthus spp.SeedsEmergingA carrier disaccharide studied for its role in delivering heart-active cardiotonic glycoside compounds.
Inulobiose—Carbohydrates (Fiber / Disaccharide)ChicoryCichorium intybusRootModerateThe repeating β(2→1) fructose-fructose unit of prebiotic inulin; essential marker for dietary fiber quality.
Levanobiose—Carbohydrates (Fiber / Disaccharide)Timothy GrassPhleum pratenseLeavesModerateA β(2→6)-linked fructose disaccharide; the structural unit of levan fiber with prebiotic and heart-healthy properties.
OLIGOSACCHARIDES
RaffinoseCAS 512-69-6Melitose; GossyposeCarbohydrates (Sugar / Oligosaccharide)PeaPisum sativumSeedModerateA common prebiotic that selectively feeds beneficial gut microbes; may cause gas in sensitive individuals.
StachyoseCAS 470-55-3LupeoseCarbohydrates (Sugar / Oligosaccharide)SoybeansGlycine maxSeedModerateFuels beneficial bacteria in the colon, supporting digestive immunity and a balanced gut microbiome.
Verbascose—Carbohydrates (Sugar / Oligosaccharide)MulleinVerbascum spp.SeedModerateA prebiotic pentasaccharide found in legumes and grains that supports a diverse and healthy gut environment.
Ajugose—Carbohydrates (Sugar / Oligosaccharide)BugleweedAjuga reptansLeavesEmergingA five-unit fructooligosaccharide being studied for its long-term prebiotic benefits to lower colon health.
Umbelliferose—Carbohydrates (Sugar / Oligosaccharide)CarrotDaucus carotaRootEmergingUnique to the Apiaceae (carrot) family; contributes to the prebiotic activity of root vegetable fibers.
Ciceritol—Carbohydrates (Sugar / Oligosaccharide)ChickpeaCicer arietinumSeedModerateImproves digestive health by selectively promoting the growth of beneficial Bifidobacteria in the intestine.
1-KestoseGF2; 1F-FructosylsucroseCarbohydrates (Sugar / Oligosaccharide)OnionAllium cepaBulbModerateA short-chain FOS highly effective at reducing gut inflammation and reinforcing the intestinal barrier function.
NystoseGF3; FructosylkestoseCarbohydrates (Sugar / Oligosaccharide)AsparagusAsparagus officinalisSpearModerateSupports metabolic wellness and has been shown to improve intestinal absorption of calcium from food.
FructofuranosylnystoseGF4; Fructooligosaccharide DP4Carbohydrates (Sugar / Oligosaccharide)GarlicAllium sativumBulbModerateEnhances immune function by selectively supporting the growth of beneficial bifidobacteria and lactobacilli.
Melezitose—Carbohydrates (Sugar / Oligosaccharide)LarchLarix occidentalisSapModerateA three-unit sugar found in honeydew honey; provides a steady energy release with a low insulin response.
Planteose—Carbohydrates (Sugar / Oligosaccharide)PlantainPlantago spp.SeedModerateFound in Plantago seeds; contributes to the mucilaginous, digestion-soothing properties of the whole seed.
Erlose—Carbohydrates (Sugar / Oligosaccharide)Various PlantsNectarEmergingA minor trisaccharide component of raw honey and nectar; contributes to its overall nutritional energy profile.
MaltotrioseCAS 1109-28-0—Carbohydrates (Sugar / Oligosaccharide)RiceOryza sativaGrainsModerateA three-unit glucose chain released during starch digestion; provides a source of sustained physical energy.
Panose—Carbohydrates (Sugar / Oligosaccharide)CornZea maysGrainsModerateA branched glucose trisaccharide from slow-digesting starches; helps maintain balanced blood sugar after meals.
Maltotetraose—Carbohydrates (Sugar / Oligosaccharide)CornZea maysGrainsModerateUsed in clinical nutrition to provide sustained, controlled energy delivery for patients with metabolic needs.
Galactotetraose—Carbohydrates (Sugar / Oligosaccharide)SoybeanGlycine maxSeedModerateA complex prebiotic oligosaccharide that helps protect the gut mucosa from inflammatory insult.
Verbascotetraose—Carbohydrates (Sugar / Oligosaccharide)MulleinVerbascum spp.SeedEmergingA four-unit oligosaccharide that helps moderate the enzymatic digestion rate of dietary starches.
Lychnose—Carbohydrates (Sugar / Oligosaccharide)CampionSilene spp.RootsEmergingA rare tetrasaccharide with prebiotic potential; studied for its benefits to lower digestive tract health.
Isolychnose—Carbohydrates (Sugar / Oligosaccharide)LychnisLychnis spp.RootsEmergingActs as a specialized plant fiber to help improve the frequency and comfort of healthy digestion.
Isomaltotriose—Carbohydrates (Sugar / Oligosaccharide)CornZea maysGrainsModerateSlows glucose absorption from branched starches, helping to keep post-meal insulin levels stable.
Neokestose—Carbohydrates (Sugar / Oligosaccharide)OnionAllium cepaBulbModerateA high-potency prebiotic shown to help lower blood cholesterol and triglyceride levels.
Maltopentaose—Carbohydrates (Sugar / Oligosaccharide)CornZea maysGrainsModerateA five-unit glucose chain used in clinical nutrition for controlled energy release in metabolic conditions.
Maltohexaose—Carbohydrates (Sugar / Oligosaccharide)CornZea maysGrainsModerateSupports long-term glycogen energy stores in the body during periods of sustained physical activity.
Maltoheptaose—Carbohydrates (Sugar / Oligosaccharide)CornZea maysGrainsModerateA seven-unit glucose chain allowing controlled release of glucose into the bloodstream over several hours.
Gentianose—Carbohydrates (Sugar / Oligosaccharide)GentianGentiana luteaRootModerateProvides the signature bitter prebiotic activity that supports healthy digestive flow and enzyme secretion.
Mannotriose—Carbohydrates (Sugar / Oligosaccharide)Ivory Nut PalmPhytelephas spp.SeedEmergingA slow-digesting mannose trisaccharide that supports a steady and healthy metabolic energy rate.
Xylotriose—Carbohydrates (Sugar / Oligosaccharide)WheatTriticum aestivumStemEmergingA xylose-derived oligosaccharide contributing to insoluble roughage that supports a healthy, clean colon.
Arabinotriose—Carbohydrates (Sugar / Oligosaccharide)All PlantsCell WallEmergingA cell-wall fiber breakdown product that helps soften the stool and ease digestive transit.
Cellotriose—Carbohydrates (Sugar / Oligosaccharide)CottonGossypium hirsutumFiberEmergingA cellulose-derived roughage oligosaccharide that helps manage inflammation in the lower gut.
SUGAR ALCOHOLS (POLYOLS)
MannitolCAS 69-65-8Mannite; Manna Sugar; E421Carbohydrates (Sugar / Sugar Alcohol)Olive TreeOlea europaeaLeavesHighA powerful osmotic agent and antioxidant that can cross the blood-brain barrier to protect the nervous system.
SorbitolCAS 50-70-4Glucitol; D-Sorbitol; E420Carbohydrates (Sugar / Sugar Alcohol)AppleMalus domesticaFruitHighA natural sugar substitute and osmotic laxative used in diabetic-friendly products to support regularity.
XylitolCAS 87-99-0Birch Sugar; E967Carbohydrates (Sugar / Sugar Alcohol)Birch TreeBetula spp.BarkHighClinically proven to prevent tooth decay and inhibit the bacteria responsible for ear infections.
ErythritolCAS 149-32-6Meso-erythritol; E968Carbohydrates (Sugar / Sugar Alcohol)StrawberryFragaria spp.FruitHighA nearly zero-calorie sweetener that protects against dental cavities and is exceptionally well-tolerated by the gut.
GalactitolCAS 608-66-2DulcitolCarbohydrates (Sugar / Sugar Alcohol)Spindle TreeEuonymus spp.LeavesEmergingStudied for its potential to help regulate osmotic water balance in human cells under metabolic stress.
Myo-inositolCAS 87-89-8Inositol; Vitamin B8 (unofficial); CyclohexanehexolCarbohydrates (Sugar / Sugar Alcohol)All PlantsEvery CellHighVital for women’s reproductive health and hormonal balance; well-validated for improving mood and insulin sensitivity.
VolemitolD-β-SedoheptitolCarbohydrates (Sugar / Sugar Alcohol)CowslipPrimula verisRootEmergingA specialized seven-carbon polyol that provides low-calorie energy support for a healthy metabolism.
Persitol—Carbohydrates (Sugar / Sugar Alcohol)AvocadoPersea americanaFruitEmergingA rare polyol contributing to the heart-healthy nutritional profile of avocados; may support satiety signals.
RibitolCAS 488-81-3AdonitolCarbohydrates (Sugar / Sugar Alcohol)Pheasant’s EyeAdonis spp.Whole PlantModerateA critical structural molecule the body uses in the synthesis of Vitamin B2 (Riboflavin) for cellular energy.
ArabitolArabinitolCarbohydrates (Sugar / Sugar Alcohol)Lichens / AlgaeWhole BodyEmergingAssists in the healthy fermentation of dietary plant fibers by bacteria in the lower digestive tract.
ThreitolL-ThreitolCarbohydrates (Sugar / Sugar Alcohol)Various PlantsLeavesEmergingFunctions as a natural antioxidant that helps neutralize harmful free radicals within the body.
D-Bornesitol1-O-Methyl-D-myo-inositolCarbohydrates (Sugar / Sugar Alcohol)LitchiLitchi chinensisLeavesEmergingA methylated inositol that improves cellular glucose uptake, helping to lower blood sugar naturally.
D-Ononitol4-O-Methyl-D-myo-inositolCarbohydrates (Sugar / Sugar Alcohol)Pigeon PeaCajanus cajanLeavesEmergingSupports cellular health during physical stress and helps maintain osmotic water balance in the body.
Sequoyitol5-O-Methyl-myo-inositolCarbohydrates (Sugar / Sugar Alcohol)RedwoodSequoia sempervirensHeartwoodEmergingProvides metabolic support and has been investigated for potential anti-diabetic and antioxidant activity.
D-PinitolCAS 525-01-93-O-Methyl-D-chiro-inositol; PinitolCarbohydrates (Sugar / Sugar Alcohol)Carob TreeCeratonia siliquaLeavesModerateA powerful insulin-sensitizing compound that helps the human body manage blood glucose more efficiently.
Pinpollitol3-O-Methyl-D-pinitolCarbohydrates (Sugar / Sugar Alcohol)Pine TreePinus spp.SapEmergingStudied for systemic water balance management and potential support for metabolic kidney function.
QuebrachitolCAS 480-40-02-O-Methyl-L-chiro-inositolCarbohydrates (Sugar / Sugar Alcohol)Rubber TreeHevea brasiliensisLatexEmergingStudied as a health-promoting agent for managing metabolic conditions, with potential gut-supportive properties.
D-Glucosaminitol—Carbohydrates (Sugar / Sugar Alcohol)Various PlantsVariousEmergingA reduced amino sugar studied for its ability to send healing signals through connective tissues.
D-RhamnitolL-RhamnitolCarbohydrates (Sugar / Sugar Alcohol)Various PlantsVariousEmergingUsed in wellness research to study healthy cellular water distribution and protection from dehydration.
L-Fucitol—Carbohydrates (Sugar / Sugar Alcohol)Various PlantsVariousEmergingAssists the body in maintaining its natural antioxidant shield under conditions of physical and oxidative stress.
D-Galactosaminitol—Carbohydrates (Sugar / Sugar Alcohol)Various PlantsVariousEmergingA vital biochemical intermediate helping scientists understand how the body synthesizes brain-healthy lipids.
STARCHES (POLYSACCHARIDES)
AmyloseCAS 9005-82-7—Carbohydrates (Starch / Polysaccharide)RiceOryza sativaGrainsModerateA linear ‘slow carb’ that digests gradually, providing stable blood energy and promoting prolonged satiety.
AmylopectinCAS 9037-22-3—Carbohydrates (Starch / Polysaccharide)PotatoSolanum tuberosumTuberModerateProvides rapidly available, highly branched glucose chains for quick muscle energy recovery after exertion.
FIBER POLYSACCHARIDES — PLANT
InulinCAS 9005-80-5Chicory Fiber; Fructan; Alant StarchCarbohydrates (Fiber / Polysaccharide)ChicoryCichorium intybusRootHighImproves bone mineral density by enhancing calcium absorption; lowers blood triglycerides and feeds beneficial gut flora.
LevanCAS 9013-95-0Bacterial Fructan (class)Carbohydrates (Fiber / Polysaccharide)GrassesPoaceaeStemsModerateA β(2→6)-linked fructan fiber that helps reduce blood cholesterol and supports immune system modulation.
CelluloseCAS 9004-34-6Microcrystalline Cellulose (MCC); E460Carbohydrates (Fiber / Polysaccharide)CottonGossypium hirsutumSeed FiberHighProvides essential bulk to the diet, promoting regularity and reducing the risk of colorectal complications.
XyloglucanCAS 37294-28-3Tamarind Seed Polysaccharide (TSP)Carbohydrates (Fiber / Polysaccharide)TamarindTamarindus indicaSeedModerateUsed in research to protect stomach and intestinal mucosal linings and to support skin barrier function.
ArabinoxylanCAS 68911-25-1AXOS (oligomeric form)Carbohydrates (Fiber / Polysaccharide)WheatTriticum aestivumBranModerateSignificantly lowers postprandial blood sugar response and promotes the selective growth of healthy gut bacteria.
GlucomannanCAS 37220-17-0Konjac Fiber; KGM; Konjac GlucomannanCarbohydrates (Fiber / Polysaccharide)KonjacAmorphophallus konjacTuberHighA clinically validated super-fiber that promotes significant weight management by inducing prolonged satiety.
GalactomannanCAS 11078-30-1(Source-specific, e.g. Guar Galactomannan)Carbohydrates (Fiber / Polysaccharide)Guar BeanCyamopsis tetragonolobaSeedHighClinically shown to lower LDL cholesterol and slow the intestinal absorption of dietary sugars.
Glucuronoxylan—Carbohydrates (Fiber / Polysaccharide)Birch TreeBetula spp.WoodModerateA hardwood hemicellulose fiber that supports the selective growth of healthy bacteria in the large intestine.
Galactoglucomannan—Carbohydrates (Fiber / Polysaccharide)Pine TreePinus spp.WoodModerateStudied for its ability to modulate immune function and support overall gut microbial balance.
Mixed-linkage Beta-glucanCAS 9041-22-9Oat Beta-Glucan; Cereal Beta-Glucan; (1→3),(1→4)-β-D-glucanCarbohydrates (Fiber / Polysaccharide)OatsAvena sativaGrainsHighCarries an FDA Qualified Health Claim for reducing LDL cholesterol and lowering the risk of heart disease.
HomogalacturonanPectin backbone; HGACarbohydrates (Fiber / Polysaccharide)AppleMalus domesticaFruitModerateThe primary pectin domain that binds dietary cholesterol and environmental heavy metals for elimination.
Rhamnogalacturonan IRG-ICarbohydrates (Fiber / Polysaccharide)CarrotDaucus carotaRootModerateBoosts the body’s natural defense against seasonal viruses and supports a resilient intestinal barrier.
Rhamnogalacturonan IIRG-IICarbohydrates (Fiber / Polysaccharide)Wine GrapesVitis viniferaFruitModerateA highly complex pectin domain that helps maintain the structural integrity of the human intestinal wall.
XylogalacturonanXGACarbohydrates (Fiber / Polysaccharide)PeaPisum sativumPodModerateA pectin sub-domain that supports long-term digestive regularity and prevents postprandial insulin spikes.
Apiogalacturonan—Carbohydrates (Fiber / Polysaccharide)DuckweedLemna minorWhole PlantEmergingA specialized pectin-domain fiber that promotes a diverse and healthy population of gut bacteria.
Arabinan—Carbohydrates (Fiber / Polysaccharide)Sugar BeetBeta vulgarisRootModerateA branched arabinose-rich fiber that acts as a gentle prebiotic, improving stool consistency and digestive ease.
Galactan—Carbohydrates (Fiber / Polysaccharide)PotatoSolanum tuberosumTuberModerateSupports the renewal and structural integrity of the protective mucus layer in the stomach and intestines.
ArabinogalactanAG; Larch ArabinogalactanCarbohydrates (Fiber / Polysaccharide)Larch TreeLarix occidentalisWoodModerateSignificantly increases beneficial gut bacteria counts and supports immune function via multiple human trials.
Gum ArabicCAS 9000-01-5Acacia Gum; E414Carbohydrates (Fiber / Polysaccharide)Acacia TreeAcacia senegalSapModerateReduces systemic inflammation and promotes satiety, aiding in healthy weight management and gut balance.
Gum TragacanthCAS 9000-65-1E413Carbohydrates (Fiber / Polysaccharide)AstragalusAstragalus brachycalyxSapModerateA traditional soothing remedy for digestive irritation; used as a prebiotic and to support skin health.
Gum KarayaCAS 9000-36-6Sterculia Gum; E416Carbohydrates (Fiber / Polysaccharide)Sterculia TreeSterculia urensSapModerateA natural bulk-forming laxative that is gentle and consistently effective for managing digestive health.
Gum GhattiCAS 9000-28-6E419Carbohydrates (Fiber / Polysaccharide)AxlewoodAnogeissus latifoliaSapModerateSupports the controlled release of nutrients in the gut, ensuring a steady and comfortable energy absorption.
Albizia Gum—Carbohydrates (Fiber / Polysaccharide)AlbiziaAlbizia zygiaSapEmergingUsed in wellness products to support healthy gut microflora populations and promote smooth, comfortable digestion.
Khaya GumAfrican Mahogany GumCarbohydrates (Fiber / Polysaccharide)MahoganyKhaya grandifoliolaSapEmergingA prebiotic exudate gum that helps maintain a healthy balance of bacteria in the human colon.
Neem Gum—Carbohydrates (Fiber / Polysaccharide)Neem TreeAzadirachta indicaSapModeratePossesses natural gastroprotective properties that help shield the stomach mucosa from ulcers and irritation.
Cashew Gum—Carbohydrates (Fiber / Polysaccharide)Cashew TreeAnacardium occidentaleSapModerateProvides a protective coating for the digestive tract and has documented immunostimulatory properties.
Almond Gum—Carbohydrates (Fiber / Polysaccharide)Almond TreePrunus dulcisSapModerateTraditionally used to soothe dry coughs and sore throats when used in herbal wellness infusions.
Okra Mucilage—Carbohydrates (Fiber / Polysaccharide)OkraAbelmoschus esculentusFruit PodModerateBinds to dietary toxins and cholesterol in the gut, helping to reduce their absorption into the bloodstream.
Psyllium MucilageCAS 9067-32-7Ispaghula; Psyllium Husk Fiber; Plantago FiberCarbohydrates (Fiber / Polysaccharide)PlantagoPlantago ovataSeed HuskHighOne of the most clinically validated fibers for reducing LDL cholesterol and supporting long-term digestive regularity.
Flaxseed MucilageLinseed Mucilage; Flaxseed FiberCarbohydrates (Fiber / Polysaccharide)FlaxLinum usitatissimumSeed CoatModerateClinical evidence supports its role in reducing blood pressure and inflammation while supporting hormonal balance.
Chia MucilageChia Seed Fiber; Chia GelCarbohydrates (Fiber / Polysaccharide)ChiaSalvia hispanicaSeedModeratePromotes hydration and stable blood sugar by forming a gel that slows carbohydrate digestion and absorption.
Tamarind Seed PolysaccharideTSP; Tamarind XyloglucanCarbohydrates (Fiber / Polysaccharide)TamarindTamarindus indicaSeedModerateSupports immune function; used in clinical ophthalmic research to protect and hydrate eye surface tissues.
Locust Bean GumCAS 9000-40-6Carob Gum; LBG; E410Carbohydrates (Fiber / Polysaccharide)Carob TreeCeratonia siliquaSeedHighClinically used to manage infant reflux and shown to support healthy postprandial blood sugar in adults.
Guar GumCAS 9000-30-0Guar; Jaguar Gum; E412Carbohydrates (Fiber / Polysaccharide)GuarCyamopsis tetragonolobaSeedHighClinically validated for treating irritable bowel syndrome (IBS) and improving overall gut motility.
Tara GumE417Carbohydrates (Fiber / Polysaccharide)Tara TreeCaesalpinia spinosaSeedModerateA gentle, well-tolerated galactomannan fiber that supports regularity and promotes a feeling of fullness.
Slippery Elm Mucilage—Carbohydrates (Fiber / Polysaccharide)Slippery ElmUlmus rubraInner BarkModerateCreates a soothing, protective coating in the human throat and stomach, effectively easing acid reflux discomfort.
Aloe Vera Gel (Acemannan)Acemannan; Aloe PolysaccharideCarbohydrates (Fiber / Polysaccharide)AloeAloe veraLeavesModerateWell-supported for internal gut healing and repair and external skin hydration and wound recovery.
Marshmallow MucilageAlthaea MucilageCarbohydrates (Fiber / Polysaccharide)Marsh MallowAlthaea officinalisRootModerateHighly effective for soothing irritated mucosal linings in both the respiratory and digestive systems.
Cactus MucilageNopal Fiber; Prickly Pear PolysaccharideCarbohydrates (Fiber / Polysaccharide)Prickly PearOpuntia ficus-indicaStem PadModerateHelps lower blood sugar and blood cholesterol while providing deep hydration to body tissues.
Fenugreek MucilageFenugreek Fiber; Trigonella GalactomannanCarbohydrates (Fiber / Polysaccharide)FenugreekTrigonella foenum-graecumSeedModerateCommonly used to improve insulin sensitivity; well-supported for healthy breast milk production in nursing mothers.
Quince MucilageQuince Seed PolysaccharideCarbohydrates (Fiber / Polysaccharide)QuinceCydonia oblongaSeedModeratePossesses natural antibacterial properties that help maintain the health of the mouth and digestive tract.
Mullein Mucilage—Carbohydrates (Fiber / Polysaccharide)MulleinVerbascum spp.LeavesModerateSupports lung health by helping to loosen and clear mucus while soothing the respiratory mucous membrane.
Licorice MucilageLicorice Root PolysaccharideCarbohydrates (Fiber / Polysaccharide)LicoriceGlycyrrhiza glabraRootModerateWell-documented for helping heal stomach ulcers and providing a soothing effect on the digestive system.
Malabar Spinach MucilageBasella MucilageCarbohydrates (Fiber / Polysaccharide)Malabar SpinachBasella albaLeavesModerateA cooling wellness food that supports gentle detoxification and helps naturally reduce body heat.
Jute MucilageCorchorus MucilageCarbohydrates (Fiber / Polysaccharide)JuteCorchorus spp.LeavesModerateRich in antioxidant polysaccharides and dietary fibers that support healthy skin and overall digestion.
Nagaimo MucilageChinese Yam Mucilage; YamaimoCarbohydrates (Fiber / Polysaccharide)Chinese YamDioscorea polystachyaTuberModerateA traditional wellness food widely used to boost kidney health and support physical stamina and vitality.
Sundew Mucilage—Carbohydrates (Fiber / Polysaccharide)SundewDrosera spp.LeavesEmergingStudied for its potential to act as a natural anti-inflammatory for muscle and joint discomfort.
Butterwort Mucilage—Carbohydrates (Fiber / Polysaccharide)ButterwortPinguicula spp.LeavesEmergingA rare biological adhesive used in research to understand how polysaccharides can address microbial infections.
Callose(1→3)-β-D-Glucan (plant)Carbohydrates (Fiber / Polysaccharide)All Higher PlantsPhloemEmergingA structural β-glucan that researchers use to study how the human body initiates and manages wound healing.
XylinanXylan (hardwood form)Carbohydrates (Fiber / Polysaccharide)Hardwood TreesHeartwoodModerateProvides extremely tough insoluble dietary roughage that helps sweep the colon clean of metabolic waste.
FIBER POLYSACCHARIDES — MARINE & ALGAL
Paramylon(1→3)-β-D-Glucan (Euglena)Carbohydrates (Fiber / Polysaccharide)EuglenaEuglena gracilisWhole CellEmergingA unique microalgal beta-glucan being studied for its ability to significantly enhance the human immune response.
Laminarin(1→3),(1→6)-β-D-Glucan (marine)Carbohydrates (Fiber / Polysaccharide)Brown AlgaeLaminaria spp.Whole BodyModerateAn algal fiber shown to help lower blood pressure and support overall cardiovascular system health.
Alginic AcidCAS 9005-32-7Alginate; Algin; E400Carbohydrates (Fiber / Polysaccharide)KelpMacrocystis pyriferaCell WallModerateUsed clinically to treat acid reflux by forming a viscous raft that physically prevents stomach acid from rising.
CarrageenanCAS 9000-07-1Irish Moss Extract; E407Carbohydrates (Fiber / Polysaccharide)Irish MossChondrus crispusCell WallModerateA sulfated seaweed polysaccharide gel that can support digestive health when consumed in food-grade form.
AgarCAS 9002-18-0Agar-agar; Kanten; E406Carbohydrates (Fiber / Polysaccharide)Red SeaweedGelidium spp.Cell WallModerateA calorie-free gelling fiber that promotes satiety and aids weight management by increasing food volume.
FucoidanCAS 9072-19-9Sulfated Fucose Polymer; Brown Algae ExtractCarbohydrates (Fiber / Polysaccharide)BladderwrackFucus vesiculosusSurfaceModerateA well-studied marine polysaccharide with documented antiviral, anticoagulant, and early-stage anticancer properties.
Ulvan—Carbohydrates (Fiber / Polysaccharide)Sea LettuceUlva lactucaCell WallEmergingSupports human detoxification pathways and helps maintain a healthy immune balance in the gut.
Porphyran—Carbohydrates (Fiber / Polysaccharide)NoriPorphyra spp.Cell WallEmergingStudied for its ability to improve fat metabolism and protect the liver from oxidative damage.
LichenanMixed-linkage β-glucan (lichen)Carbohydrates (Fiber / Polysaccharide)Iceland MossCetraria islandicaThallusModerateA traditional respiratory soother; provides slow-release energy and supports the body’s mucosal defenses.
Pustulan(1→6)-β-D-Glucan (lichen)Carbohydrates (Fiber / Polysaccharide)Rock TripeLasallia pustulataThallusEmergingUsed as a molecular research tool to investigate new ways to boost human intestinal immunity.
FIBER POLYSACCHARIDES — FUNGAL
ChitinCAS 1398-61-4Poly-GlcNAc; Fungal FiberCarbohydrates (Fiber / Polysaccharide)MushroomsAgaricus bisporusCell WallModerateProvides structural roughage that aids in healthy weight management and promotes colon health.
LentinanCAS 37339-90-5Shiitake Beta-Glucan; LNTCarbohydrates (Fiber / Polysaccharide)ShiitakeLentinula edodesFruit BodyModerateA clinically used immunostimulant (approved in Japan) that helps the body defend against tumors and viral infections.
SchizophyllanSonifilan; SPG; SIZOFIRANCarbohydrates (Fiber / Polysaccharide)Splitgill MushroomSchizophyllum communeMyceliumModerateInvestigated for its ability to stimulate production of infection-fighting white blood cells via NK cell activation.
Scleroglucan—Carbohydrates (Fiber / Polysaccharide)Soil FungiSclerotium spp.MyceliumEmergingUsed in wellness products to provide sustained skin hydration and topical barrier support.
PullulanCAS 9057-02-7E1204Carbohydrates (Fiber / Polysaccharide)FungiAureobasidium pullulansSurfaceModerateA food-grade biopolymer used in dissolvable wellness films and capsules; safe and easily digested.
FATTY ACIDS — SATURATED
Lauric AcidCAS 143-07-7Dodecanoic acid; C12:0Lipids (Fatty Acid / Saturated)Coconut PalmCocos nuciferaEndospermModerateA medium-chain saturated fatty acid that is rapidly metabolised for energy; may support healthy immune function.
Myristic AcidCAS 544-63-8Tetradecanoic acid; C14:0Lipids (Fatty Acid / Saturated)NutmegMyristica fragransSeedModeratePlays a structural role in anchoring proteins to cell membranes and may contribute to healthy cellular signalling.
Palmitic AcidCAS 57-10-3Hexadecanoic acid; C16:0Lipids (Fatty Acid / Saturated)Palm TreeElaeis guineensisFruit MesocarpHighA foundational saturated fatty acid that serves as a key energy substrate and essential structural component of human cell membranes.
Stearic AcidCAS 57-11-4Octadecanoic acid; C18:0Lipids (Fatty Acid / Saturated)Cocoa TreeTheobroma cacaoSeed (Bean)HighA stable saturated fatty acid providing sustained energy; appears to have a more neutral effect on blood cholesterol than shorter-chain saturated fats.
Arachidic AcidCAS 506-30-9Eicosanoic acid; C20:0Lipids (Fatty Acid / Saturated)PeanutArachis hypogaeaSeedEmergingA minor long-chain saturated fatty acid that may contribute to long-term energy storage and structural cell membrane integrity.
Behenic AcidCAS 112-85-6Docosanoic acid; C22:0Lipids (Fatty Acid / Saturated)MoringaMoringa oleiferaSeedModerateWidely used in topical formulations for emollient properties; may support skin smoothness and moisture retention.
Lignoceric AcidCAS 557-59-5Tetracosanoic acid; C24:0Lipids (Fatty Acid / Saturated)PeanutArachis hypogaeaSeedModerateA very long-chain fatty acid that forms part of the brain's myelin sheath structure, supporting nerve insulation and integrity.
FATTY ACIDS — MONOUNSATURATED
Palmitoleic AcidCAS 373-49-9C16:1 n-7; Omega-7Lipids (Fatty Acid / Monounsaturated)MacadamiaMacadamia integrifoliaNutModerateMay support metabolic health and help maintain mucosal lining hydration; studied for potential lipid-management benefits.
Petroselinic AcidCAS 593-39-5C18:1 (6Z); Delta-6-octadecenoic acidLipids (Fatty Acid / Monounsaturated)ParsleyPetroselinum crispumSeedEmergingMay contribute to skin health and localised inflammation modulation; studied for cosmetic and topical wellness applications.
Oleic AcidCAS 112-80-1Octadecenoic acid; C18:1 n-9; Omega-9Lipids (Fatty Acid / Monounsaturated)Olive TreeOlea europaeaFruitHighA well-documented heart-supportive fatty acid; consistently associated with healthy arterial function and favourable lipid profiles as part of a balanced diet.
Gadoleic AcidC20:1 n-9; Eicosenoic acidLipids (Fatty Acid / Monounsaturated)RapeseedBrassica napusSeedEmergingContributes to fatty acid diversity in cell membranes; studied for its minor role in lipid metabolism and chain elongation.
Gondoic AcidC20:1 n-11; Eicosenoic acid (n-11)Lipids (Fatty Acid / Monounsaturated)JojobaSimmondsia chinensisSeedModerateClosely resembles the body's natural sebum; may support skin and hair hydration in topical wellness formulations.
Erucic AcidCAS 112-86-7C22:1 n-9; Long-chain Omega-9Lipids (Fatty Acid / Monounsaturated)MustardBrassica nigraSeedModerateStudied in specific therapeutic contexts for neurological support; dietary intake is subject to regulatory guidance in many markets due to cardiac safety considerations.
Nervonic AcidCAS 506-37-6Selacholeic acid; C24:1 n-9Lipids (Fatty Acid / Monounsaturated)Honesty PlantLunaria annuaSeed OilModerateA very long-chain fatty acid considered important for maintaining the structural health of the brain's white matter and myelin insulation.
FATTY ACIDS — POLYUNSATURATED (OMEGA-6)
Linoleic AcidCAS 60-33-3LA; C18:2 n-6; Omega-6Lipids (Fatty Acid / Polyunsaturated)SunflowerHelianthus annuusSeedHighAn essential omega-6 fatty acid required for normal skin barrier function, hormonal balance, and the body's inflammatory regulation.
Gamma-Linolenic AcidCAS 506-26-3GLA; C18:3 n-6; Omega-6Lipids (Fatty Acid / Polyunsaturated)BorageBorago officinalisSeedModerateMay help support hormonal balance and healthy skin; studied for its role in modulating prostaglandin-mediated inflammatory pathways.
Arachidonic AcidCAS 506-32-1AA; ARA; C20:4 n-6Lipids (Fatty Acid / Polyunsaturated)MossesPhyscomitrella patensWhole PlantHighA key structural and signalling omega-6 fatty acid required for the synthesis of eicosanoids governing pain, sleep, and inflammatory balance.
Columbinic AcidC18:3 (5t,9c,12c)Lipids (Fatty Acid / Polyunsaturated)Meadow RueThalictrum aquilegifoliumSeedEmergingA rare trans-containing polyunsaturated fatty acid studied for potential structural and metabolic roles in lipid biology.
Mead AcidCAS 20590-32-3C20:3 n-9; 5,8,11-Eicosatrienoic acidLipids (Fatty Acid / Polyunsaturated)PrimroseOenothera spp.SeedEmergingProduced by the body when essential fatty acid intake is low; studied as a biomarker for evaluating omega-3 and omega-6 nutritional status.
Coriolic Acid13-Hydroxy-9,11-octadecadienoic acidLipids (Fatty Acid / Polyunsaturated)CoriariaCoriaria myrtifoliaSeedEmergingA hydroxy fatty acid studied in early-stage research for its potential to help modulate the body's inflammatory response.
FATTY ACIDS — POLYUNSATURATED (OMEGA-3)
alpha-Linolenic AcidCAS 463-40-5ALA; C18:3 n-3; Omega-3Lipids (Fatty Acid / Polyunsaturated)FlaxLinum usitatissimumSeedModerateA plant-source omega-3 fatty acid; may support cardiovascular health and normal inflammatory balance when consumed as part of a varied diet.
Stearidonic AcidCAS 20290-75-9SDA; C18:4 n-3; Omega-3Lipids (Fatty Acid / Polyunsaturated)HempCannabis sativaSeedModerateAn omega-3 fatty acid that may convert to EPA more efficiently than ALA; studied for potential cardiovascular and inflammatory benefits.
Eicosapentaenoic AcidCAS 10417-94-4EPA; C20:5 n-3; Omega-3Lipids (Fatty Acid / Polyunsaturated)MicroalgaeNannochloropsis spp.Whole CellHighPlays a well-documented role in supporting normal blood triglyceride levels and healthy inflammatory balance.
Docosapentaenoic AcidCAS 53988-10-6DPA; C22:5 n-3; Omega-3Lipids (Fatty Acid / Polyunsaturated)MicroalgaeSchizochytrium spp.Whole CellModerateA metabolic intermediate between EPA and DHA; studied for potential cardiovascular and neural health support.
Docosahexaenoic AcidCAS 6217-54-5DHA; C22:6 n-3; Omega-3Lipids (Fatty Acid / Polyunsaturated)MicroalgaeSchizochytrium spp.Whole CellHighA critical omega-3 fatty acid required for normal brain development and the maintenance of healthy visual function throughout life.
Sciadonic AcidC20:3 n-6 (5,11,14-eicosatrienoic)Lipids (Fatty Acid / Polyunsaturated)Umbrella PineSciadopitys verticillataSeedEmergingA non-conventional polyunsaturated fatty acid studied for potential anti-inflammatory properties at the cardiovascular level.
FATTY ACIDS — CONJUGATED & SPECIALIZED
Punicic AcidCAS 544-72-9Trichosanic acid; Omega-5 CLALipids (Fatty Acid / Conjugated)PomegranatePunica granatumSeed OilModerateA conjugated omega-5 fatty acid studied for its potential to support healthy insulin sensitivity and metabolic balance.
Calendic AcidBeta-calendic acid; C18:3 (8t,10t,12c)Lipids (Fatty Acid / Conjugated)MarigoldCalendula officinalisSeedEmergingA conjugated fatty acid studied for antioxidant and mild anti-inflammatory properties; of interest for skin health applications.
Catalpic AcidC18:3 (9t,11t,13c)Lipids (Fatty Acid / Conjugated)Catalpa TreeCatalpa spp.SeedEmergingAn unusual trans-conjugated fatty acid studied for potential contributions to a healthy cardiovascular lipid profile.
Eleostearic AcidAlpha-eleostearic acid; C18:3 (9c,11t,13t)Lipids (Fatty Acid / Conjugated)Bitter GourdMomordica charantiaSeedEmergingStudied in laboratory settings for potential antiproliferative properties; early-stage research, not established in human studies.
Parinaric AcidAlpha-parinaric acid; C18:4 conj.Lipids (Fatty Acid / Conjugated)ParinariParinari curatellifoliaSeedEmergingA tetra-unsaturated conjugated fatty acid studied for its antioxidant potential and ability to protect cells from lipid peroxidation.
Jacaric AcidC18:3 (8c,10t,12c)Lipids (Fatty Acid / Conjugated)JacarandaJacaranda mimosifoliaSeedEmergingStudied in laboratory settings for potential proapoptotic activity against damaged or abnormal cells; early-stage research only.
Licanic Acid4-Keto-alpha-eleostearic acidLipids (Fatty Acid / Conjugated)OiticicaLicania rigidaSeedEmergingA keto-conjugated fatty acid studied for its potential role in supporting tissue healing and cellular recovery.
Pinolenic AcidCAS 16833-54-8Delta-5-linolenic acid; C18:3 (5c,9c,12c)Lipids (Fatty Acid / Specialized)Pine NutPinus sibiricaNutModerateMay support appetite regulation by stimulating the release of satiety hormones; studied in the context of weight management.
Ricinoleic AcidCAS 141-22-012-Hydroxy-9-cis-octadecenoic acidLipids (Fatty Acid / Hydroxy)Castor BeanRicinus communisSeedModerateTraditionally used to support digestive regularity; studied for potential soothing properties on smooth muscle tissue.
Vernolic Acid12,13-Epoxy-9-octadecenoic acidLipids (Fatty Acid / Epoxy)IronweedVernonia galamensisSeedEmergingAn epoxy fatty acid being studied for potential applications in skin repair and high-performance wellness formulations.
Taxoleic AcidC18:2 (5c,9c)Lipids (Fatty Acid / Specialized)Yew TreeTaxus spp.SeedEmergingA non-conventional dienoic fatty acid studied for its contribution to healthy lipid diversity in cell membranes.
Juniperic Acid16-Hydroxyhexadecanoic acidLipids (Fatty Acid / Hydroxy)JuniperJuniperus spp.NeedlesEmergingA plant wax hydroxy fatty acid studied for its minor role in maintaining protective skin and cuticle resilience.
Sabinic Acid12-Hydroxydodecanoic acidLipids (Fatty Acid / Hydroxy)Savin JuniperJuniperus sabinaNeedlesEmergingA medium-chain hydroxy fatty acid studied as a structural building block for specialised cellular lipid functions.
Phloionolic Acid9,10,18-Trihydroxyoctadecanoic acidLipids (Fatty Acid / Polyhydroxy)Cork OakQuercus suberBarkEmergingA polyhydroxy fatty acid component of plant suberin; may contribute to the structural integrity of epithelial barrier tissues.
Lesquerolic Acid14-Hydroxyeicosenoic acidLipids (Fatty Acid / Hydroxy)Fendler's BladderpodLesquerella fendleriSeedEmergingStructurally similar to ricinoleic acid; studied for potential skin and joint health applications in wellness formulations.
Chaulmoogric AcidC18 cyclopentenyl fatty acidLipids (Fatty Acid / Cyclopentenyl)ChaulmoograHydnocarpus wightianusSeedModerateTraditionally used in Ayurvedic and herbal systems to support the body's defence against skin infections.
Hydnocarpic AcidC16 cyclopentenyl fatty acidLipids (Fatty Acid / Cyclopentenyl)ChaulmoograHydnocarpus wightianusSeedModerateWorks alongside chaulmoogric acid in traditional wellness applications for skin health and immune support.
Gorlic AcidC18 cyclopentenyl fatty acid (unsaturated)Lipids (Fatty Acid / Cyclopentenyl)ChaulmoograHydnocarpus wightianusSeedModerateA cyclopentenyl fatty acid in the chaulmoogra group; traditionally studied for supporting the body's response to external pathogens.
Malvalic Acid8-(2-Octylcyclopropenyl)octanoic acidLipids (Fatty Acid / Cyclopropene)CottonGossypium hirsutumSeedEmergingA cyclopropenoid fatty acid studied for its regulatory effects on fatty acid desaturation enzyme pathways.
Sterculic Acid9-(2-Octylcyclopropenyl)nonanoic acidLipids (Fatty Acid / Cyclopropene)Sterculia TreeSterculia foetidaSeedEmergingA cyclopropenoid fatty acid studied for its inhibitory interaction with stearoyl-CoA desaturase enzymes.
Cyclopropenoid Fatty AcidCyclopropene FA class; Sterculene-typeLipids (Fatty Acid / Cyclopropene)BaobabAdansonia digitataSeedEmergingA class of unusual cyclic fatty acids contributing to the unique lipid profile of certain tropical seed oils.
HYDROXY, EPOXY & POLYHYDROXY FATTY ACIDS
10-Hydroxy-Stearic Acid10-Hydroxystearic acidLipids (Fatty Acid / Hydroxy)Various PlantsEvery CellEmergingStudied as a signalling intermediate in lipid inflammatory pathways; may contribute to healthy tissue repair processes.
9,10-Epoxy-Stearic AcidEpoxystearic acidLipids (Fatty Acid / Epoxy)Plant CuticleSurfaceEmergingA cuticle wax component studied for its potential role in maintaining healthy epithelial and mucosal surface integrity.
18-Hydroxy-Oleic Acid—Lipids (Fatty Acid / Hydroxy)PotatoSolanum tuberosumSkinEmergingA suberin-component hydroxy fatty acid studied for its contribution to the structural repair of the body's outer protective barriers.
16-Hydroxy-Palmitic AcidDihydroxypalmitic acid (partial)Lipids (Fatty Acid / Hydroxy)AppleMalus domesticaFruit PeelEmergingA plant wax hydroxy fatty acid studied for its potential role in supporting protective skin moisture retention.
9,10,18-Trihydroxy-Stearic AcidPhloionolic acid (related form)Lipids (Fatty Acid / Polyhydroxy)SpinachSpinacia oleraceaLeavesEmergingA polyhydroxy fatty acid studied for its potential contribution to gut mucosal health and digestive microbiome balance.
VERY LONG-CHAIN SATURATED FATTY ACIDS
Heneicosanoic AcidC21:0Lipids (Fatty Acid / Very Long Chain)Various PlantsSeedsEmergingA rare odd-chain saturated fatty acid; studied as a dietary biomarker and contributor to fatty acid structural diversity.
Tricosanoic AcidC23:0Lipids (Fatty Acid / Very Long Chain)LegumesSeedsEmergingAn odd-chain saturated fatty acid that may contribute to the structural complexity of human cell membranes.
Pentacosanoic AcidC25:0Lipids (Fatty Acid / Very Long Chain)Various GrainsSeedsEmergingMay support long-term energy metabolism and contribute to the structural health of nerve tissue.
Heptacosanoic AcidC27:0Lipids (Fatty Acid / Very Long Chain)Tree WaxesLeavesEmergingA plant wax fatty acid that contributes to the diversity of very long-chain lipids in the human diet.
Nonacosanoic AcidC29:0Lipids (Fatty Acid / Very Long Chain)Sugarcane WaxSaccharum officinarumStemEmergingA wax-derived fatty acid studied for its minor contribution to healthy lipid and energy balance.
Hentriacontanoic AcidC31:0Lipids (Fatty Acid / Very Long Chain)Plant WaxesLeavesEmergingA very long-chain wax fatty acid that may support the integrity and protective function of the skin barrier.
Tritriacontanoic AcidC33:0Lipids (Fatty Acid / Very Long Chain)Tropical WaxesSurfaceEmergingA rare wax fatty acid contributing to the structural stability of specialised plant wax complexes.
Pentatriacontanoic AcidC35:0Lipids (Fatty Acid / Very Long Chain)Rare Tree OilsSeedsEmergingA trace very long-chain lipid playing a minor structural role in overall cellular and membrane stability.
FATTY ALCOHOLS & WAX ALCOHOLS
Eicosanol1-Eicosanol; C20 fatty alcoholLipids (Fatty Alcohol / Wax)Sesame OilSesamum indicumSeedModerateA plant wax primary alcohol studied for its potential to support skin tissue health and recovery in topical applications.
DocosanolCAS 661-19-8Behenyl alcohol; C22 fatty alcoholLipids (Fatty Alcohol / Wax)Peanut OilArachis hypogaeaSeedModerateA long-chain fatty alcohol with studied antiviral properties; clinically investigated for managing labial viral infections.
TetracosanolLignoceryl alcohol; C24 fatty alcoholLipids (Fatty Alcohol / Wax)Rice BranOryza sativaBranModerateA plant wax component studied for its potential contribution to protecting nervous system tissues from oxidative stress.
HexacosanolCeryl alcohol; C26 fatty alcoholLipids (Fatty Alcohol / Wax)Sugar CaneSaccharum officinarumStemModerateA constituent of policosanol wax mixtures studied for potential heart-supportive properties in cholesterol management.
OctacosanolCAS 557-61-91-Octacosanol; C28 fatty alcoholLipids (Fatty Alcohol / Wax)Wheat GermTriticum aestivumSeedModerateStudied for potential benefits to exercise performance and endurance; may support healthy cholesterol balance.
TriacontanolCAS 593-50-0Melissyl alcohol; C30 fatty alcoholLipids (Fatty Alcohol / Wax)AlfalfaMedicago sativaLeavesModerateA natural plant wax alcohol studied for potential support of metabolic vitality and physical energy levels.
Hexadecanediol1,16-HexadecanediolLipids (Fatty Alcohol / Wax)Various PlantsSurfaceEmergingA diol wax component that may contribute to the stability and protective moisture function of skin barrier layers.
PhytolCAS 150-86-7Phytyl alcohol; Diterpene alcoholLipids (Diterpene Alcohol)All Green LeavesChloroplastModerateA chlorophyll breakdown product that serves as a biosynthetic precursor to Vitamins E and K in the body.
Phytanic Acid3,7,11,15-Tetramethylhexadecanoic acidLipids (Fatty Acid / Branched)SpinachSpinacia oleraceaLeavesModerateA branched-chain fatty acid derived from dietary phytol; studied for its role in managing fat and glucose metabolism.
Pristanic Acid2,6,10,14-Tetramethylpentadecanoic acidLipids (Fatty Acid / Branched)Green VegetablesLeavesEmergingA branched-chain metabolite of phytanic acid; may contribute to the healthy metabolic function of liver cells.
PHOSPHOLIPIDS & LYSOPHOSPHOLIPIDS
PhosphatidylcholineCAS 8002-43-5Lecithin; PCLipids (Phospholipid)SoybeanGlycine maxSeedHighA major dietary source of choline, supporting liver function, cognitive health, and the structural integrity of all cell membranes.
PhosphatidylethanolamineCephalin; PELipids (Phospholipid)Wheat GermTriticum aestivumSeedModerateSupports the structural integrity of brain cell membranes and may contribute to healthy neurotransmitter signalling.
PhosphatidylinositolPILipids (Phospholipid)CornZea maysGrainsModeratePlays a central role in insulin signalling and intracellular communication; may support healthy glucose response.
PhosphatidylserineCAS 51446-62-9PS; Soy PSLipids (Phospholipid)SoybeanGlycine maxSeedModerateStudied for supporting cognitive performance and age-related memory health; limited human trial data available.
PhosphatidylglycerolPGLipids (Phospholipid)SpinachSpinacia oleraceaLeavesModerateAn essential component of lung surfactant; may contribute to healthy respiratory function and airway surface integrity.
CardiolipinBisphosphatidylglycerol; CLLipids (Phospholipid)All Green PlantsEvery CellHighA mitochondria-specific phospholipid critical for cellular energy production efficiency and metabolic function.
Lyso-PhosphatidylcholineLPC; Lyso-PCLipids (Phospholipid)Various PlantsEvery CellModerateInvolved in lipid signalling pathways; studied for its role in regulating the body's tissue healing and inflammatory response.
Lyso-PhosphatidylethanolamineLPE; Lyso-PELipids (Phospholipid)Various PlantsEvery CellEmergingStudied as a bioactive signalling lipid involved in healthy cellular maturation and membrane renewal processes.
N-Acyl-PhosphatidylethanolamineNAPELipids (Phospholipid)CottonseedGossypium hirsutumSeedModerateA lipid signalling precursor that may communicate satiety signals to the brain in response to food intake.
N-AcylethanolamineNAE; Endocannabinoid-related lipidLipids (Phospholipid)SoybeanGlycine maxSeedModerateMay support the body's natural stress-modulating system; studied for potential contribution to a calm physiological state.
Phosphatidic AcidPALipids (Phospholipid)All PlantsEvery CellModerateA key lipid signalling molecule studied for its potential role in supporting muscle protein synthesis and post-exercise recovery.
GALACTOLIPIDS & SULFOLIPIDS
MonogalactosyldiacylglycerolMGDGLipids (Galactolipid)Dog RoseRosa caninaFruit (Hips)ModerateThe most abundant plant membrane lipid; studied for potential anti-inflammatory effects with relevance to joint health support.
DigalactosyldiacylglycerolDGDGLipids (Galactolipid)SpinachSpinacia oleraceaLeavesModerateA plant-source galactolipid that may help modulate inflammatory responses and support healthy immune balance.
SulfoquinovosyldiacylglycerolSQDG; Plant SulfolipidLipids (Sulfolipid)Sea LettuceUlva lactucaWhole PlantEmergingA sulfonated glycolipid studied for potential antiviral properties and its role in supporting detoxification pathways.
Acylated-MGDGAcyl-MGDGLipids (Galactolipid)ArabidopsisArabidopsis thalianaLeavesEmergingStudied for its role in lipid remodelling during cellular stress and its potential contribution to wound-healing signalling.
TRIACYLGLYCEROLS
TrioleinGlyceryl trioleateLipids (Triacylglycerol)Olive TreeOlea europaeaFruitModerateThe predominant triacylglycerol of olive oil; may support heart health by providing monounsaturated fats as part of a balanced diet.
TrilinoleinGlyceryl trilinoleateLipids (Triacylglycerol)Evening PrimroseOenothera biennisSeedModerateA source of essential linoleic acid that may support healthy skin, hair, and nail integrity.
PLANT STEROLS & STANOLS
Beta-sitosterolCAS 83-46-5Beta-Sitosterol; 24-EthylcholesterolLipids (Sterol)Wheat GermTriticum aestivumSeedHighCompetes with cholesterol for intestinal absorption; well-supported for helping maintain healthy blood cholesterol levels.
StigmasterolCAS 83-48-7—Lipids (Sterol)SoybeanGlycine maxSeedModerateMay contribute to healthy cholesterol balance; studied as a biosynthetic base for steroid hormones.
CampesterolCAS 474-62-424-MethylcholesterolLipids (Sterol)RapeseedBrassica napusSeedModerateMay support cardiovascular health by contributing to a healthy blood lipid profile.
BrassicasterolCAS 474-67-924-Methyl-delta5,22-cholestadienolLipids (Sterol)BroccoliBrassica oleraceaFloretsModerateA Brassica-specific phytosterol that may contribute to a healthy overall lipid profile.
CycloartenolCAS 469-38-5—Lipids (Sterol)Rice BranOryza sativaSeed CoatModerateA tetracyclic sterol and biosynthetic precursor to other plant sterols; studied for potential antioxidant properties.
Spinasterol—Lipids (Sterol)SpinachSpinacia oleraceaLeavesModerateA plant-specific sterol studied for its potential role in supporting healthy cholesterol metabolism.
Schottenol—Lipids (Sterol)Prickly PearOpuntia ficus-indicaSeedsModerateStudied for its potential to support healthy lipid-clearing metabolic pathways.
Lophenol—Lipids (Sterol)Aloe VeraLeavesModerateStudied for its potential to help maintain healthy blood sugar balance and support weight management.
ErgosterolCAS 57-87-4Provitamin D2Lipids (Sterol)Button MushroomAgaricus bisporusFruit BodyHighA sterol precursor that converts to Vitamin D2 on UV exposure; important for bone health and immune system support.
SitostanolCAS 19044-59-2Beta-Sitostanol; 24-EthylcholestanolLipids (Stanol)CornZea maysBranHighOne of the most effective plant-derived compounds for blocking intestinal absorption of dietary cholesterol.
CampestanolCAS 474-60-224-MethylcholestanolLipids (Stanol)OatsAvena sativaGrainsHighMay provide a synergistic sterol-lowering effect when combined with other plant sterols to support heart health.
24-Methylene-Cycloartanol—Lipids (Sterol)Rice Bran OilOryza sativaSeed CoatModerateA cycloartenol derivative studied for potential metabolic and cell-protective properties.
Sitosteryl FerulateBeta-Sitosteryl ferulate; Oryzanol componentLipids (Sterol Ester)Rice Bran OilOryza sativaBranModerateA phytosterol-ferulic acid conjugate studied for potential antioxidant and anti-inflammatory properties.
Delta-5-Avenasteroldelta5-AvenasterolLipids (Sterol)OatsAvena sativaGrainsModerateMay contribute to antioxidant protection of the cardiovascular system and support healthy lipid balance.
Delta-7-Avenasteroldelta7-AvenasterolLipids (Sterol)Sunflower OilHelianthus annuusSeedModerateMay support healthy vascular function and contribute to the maintenance of normal blood vessel resilience.
Gramisterol—Lipids (Sterol)Wheat Germ OilTriticum aestivumSeedModerateA minor grain sterol that may support normal immune function and healthy lipid metabolism.
Citrostadienol—Lipids (Sterol)Citrus OilCitrus limonPeelModerateA minor phytosterol that may contribute to healthy metabolic rate and balanced lipid function.
Isofucosteroldelta5-Avenasterol (algal/oat form)Lipids (Sterol)Oat BranAvena sativaGrain HullModerateMay support healthy management of dietary fat absorption and contribute to energy regulation.
Cycloartanol—Lipids (Sterol)Rice BranOryza sativaBranModerateA cyclopropane-containing sterol that may contribute to overall metabolic efficiency and cellular vitality.
24-Ethylidene-Lophenol—Lipids (Sterol)TobaccoNicotiana tabacumLeavesEmergingStudied as a minor sterol; may provide structural components for healthy nerve membrane architecture.
STEROL ESTERS & GLYCOSIDES
Sitosteryl GlucosideBeta-Sitosteryl-3-O-glucosideLipids (Sterol Glucoside)TomatoSolanum lycopersicumFruitModerateStudied for its potential to support cellular adaptation to physical stress and environmental metabolic changes.
Acylated Steryl GlucosideASGLipids (Sterol Glucoside)PotatoSolanum tuberosumTuberModerateMay provide long-term structural support for healthy cell membrane architecture and function.
Sitosterol-PalmitateBeta-Sitosteryl palmitateLipids (Sterol Ester)Soybean OilGlycine maxSeed OilModerateA sterol ester form that may contribute to maintaining healthy cholesterol levels over time.
Campesterol-OleateCampesteryl oleateLipids (Sterol Ester)Corn OilZea maysSeed OilModerateMay support a balanced cardiovascular lipid profile and contribute to healthy blood flow.
Stigmasterol-LinoleateStigmasteryl linoleateLipids (Sterol Ester)Rapeseed OilBrassica napusSeed OilModerateContributes to the body's supply of essential fats alongside plant-based growth-supportive sterols.
TRITERPENOIDS (PENTACYCLIC)
Ursolic AcidCAS 77-52-1Urson; Prunol; MalolLipids (Triterpenoid)AppleMalus domesticaFruit PeelModerateMay support the preservation of muscle mass and contribute to healthy metabolic balance; studied in fitness and nutrition contexts.
Oleanolic AcidCAS 508-02-1CaryophyllinLipids (Triterpenoid)Olive TreeOlea europaeaLeavesModerateMay support liver health and help maintain the body's natural defence against certain microbial challenges.
Betulinic AcidCAS 472-15-13-beta-Hydroxy-lup-20(29)-en-28-oic acidLipids (Triterpenoid)Birch TreeBetula spp.BarkEmergingStudied in laboratory settings for potential antiviral and antiproliferative properties; early-stage research only.
LupeolCAS 545-47-1Fagarasterol; Monogynol BLipids (Triterpenoid)MangoMangifera indicaFruit PeelModerateStudied for potential anti-inflammatory and skin-protective properties; some evidence for photoprotective effects on skin cells.
FriedelinCAS 559-74-0—Lipids (Triterpenoid)Cork OakQuercus suberBarkModerateExhibits potential anti-inflammatory and analgesic properties; traditionally used in topical skin-healing applications.
Erythrodiol—Lipids (Triterpenoid)Olive OilOlea europaeaFruitModerateA pentacyclic triterpenoid that may contribute to the overall antioxidant properties of olive-based diets.
Uvaol—Lipids (Triterpenoid)BearberryArctostaphylos uva-ursiLeavesModerateTraditionally associated with urinary tract health support; studied for potential anti-inflammatory properties.
TaraxerolCAS 4066-83-5—Lipids (Triterpenoid)DandelionTaraxacum officinaleRootsModerateStudied for potential liver-supportive and detoxification-promoting properties in traditional herbal wellness.
Taraxasterol—Lipids (Triterpenoid)DandelionTaraxacum officinaleFlowersModerateStudied for potential anti-inflammatory properties that may support joint and connective tissue health.
BetulinCAS 473-98-3Betulinol; BetulolLipids (Triterpenoid)Birch TreeBetula spp.BarkModerateA major birch bark constituent studied for potential contributions to skin healing and immune defence support.
SQUALENE
SqualeneCAS 111-02-4Spinacene; Supraene; C30 triterpeneLipids (Terpene / Triterpene)Olive OilOlea europaeaFruitModerateA natural triterpene emollient that may support skin hydration; studied for potential immune-modulating properties.
SPHINGOLIPIDS
PhytosphingosineCAS 554-62-14-Hydroxysphinganine; t18:0Lipids (Sphingolipid)RiceOryza sativaGrainsModerateStudied for its antimicrobial properties in skincare applications; may help support a healthy skin barrier.
GlucosylceramideGlcCer; Plant Ceramide GlucosideLipids (Sphingolipid)WheatTriticum aestivumGrainsModerateOral supplementation has been studied for its potential to improve skin hydration from within the body.
CeramideN-Acylsphingosine (class)Lipids (Sphingolipid)SoybeanGlycine maxSeedModerateStudied for its role in restoring the skin's protective barrier and reducing transepidermal water loss.
Mannosyl-Inositol-PhosphoceramideMIPCLipids (Sphingolipid)TomatoSolanum lycopersicumLeavesEmergingA complex sphingolipid studied for plant immune recognition; early-stage research into relevance for human cellular health.
Phytosphingosine-1-PhosphatePhS1PLipids (Sphingolipid)ArabidopsisArabidopsis thalianaLeavesEmergingA lipid signalling molecule associated with cellular survival signalling and healthy growth regulation.
Ceramide-1-PhosphateC1PLipids (Sphingolipid)Various PlantsEvery CellEmergingA bioactive lipid mediator studied for its signalling role in cellular repair and growth in response to physiological stimuli.
GIPC (Plant Sphingolipid)Glycosyl Inositol PhosphoceramideLipids (Sphingolipid)SoybeanGlycine maxSeedModerateThe most abundant plant sphingolipid class; studied for potential contributions to maintaining healthy cellular cholesterol balance.
Mannosyl-GIPC—Lipids (Sphingolipid)TomatoSolanum lycopersicumLeavesEmergingStudied for plant immune recognition roles; early-stage research into relevance for human gut microbiome interactions.
Arabinosyl-GIPC—Lipids (Sphingolipid)LegumesRootsEmergingMay contribute to gut microbiome diversity through its structural role in plant cell membranes; early-stage research.
Galactosyl-GIPC—Lipids (Sphingolipid)Various PlantsEvery CellEmergingA structural sphingolipid studied for its potential role in supporting healthy cell membrane communication.
Xylosyl-GIPC—Lipids (Sphingolipid)Plant MembranesCellEmergingA minor sphingolipid class studied for its relevance to the structural resilience of plant and human cell membranes.
Fucosyl-GIPC—Lipids (Sphingolipid)Plant MembranesCellEmergingPlays a role in the structural complexity of plant sphingolipid profiles; studied for relevance to human cell biology.
STORAGE PROTEINS — GLOBULINS
Glycinin11S Globulin; Soy GlobulinProtein (Globulin)SoybeanGlycine maxSeedHighA well-studied complete protein providing all essential amino acids; may support muscle maintenance and bone density.
Beta-Conglycinin7S Globulin; Soy 7SProtein (Globulin)SoybeanGlycine maxSeedModerateMay contribute to healthy blood lipid balance and support normal glucose metabolism as part of a soy-rich diet.
Phaseolin7S Vicilin; Bean GlobulinProtein (Globulin)Kidney BeanPhaseolus vulgarisSeedModerateProvides essential amino acids for cell repair; may contribute to satiety when consumed as part of a high-protein diet.
Vicilin7S Globulin; Pea Storage ProteinProtein (Globulin)Garden PeaPisum sativumSeedModerateA well-digestible plant protein that may support general growth, tissue maintenance, and physical recovery.
Legumin11S Globulin; Pea LeguminProtein (Globulin)Broad BeanVicia fabaSeedModerateSupplies a broad spectrum of amino acids; may support immune cell production and overall physical maintenance.
Amandin11S Globulin; Almond ProteinProtein (Globulin)AlmondPrunus dulcisNut KernelModerateThe primary storage protein of almonds; may support heart health and muscle tissue maintenance as part of a nut-rich diet.
EdestinCannabis Globulin; Hemp 11SProtein (Globulin)HempCannabis sativaSeedModerateA highly bioavailable plant globulin; studied for potential immune-supportive properties due to its structural similarity to human blood proteins.
Cruciferin12S Globulin; Brassica Storage ProteinProtein (Globulin)MustardSinapis albaSeedModerateA Brassica storage protein providing essential amino acids that may support normal tissue repair and regeneration.
Excelsin11S Globulin; Brazil Nut ProteinProtein (Globulin)Brazil NutBertholletia excelsaNut KernelModerateRich in selenium-containing amino acids; may support thyroid health and contribute to the antioxidant defence system.
CorylinHazelnut GlobulinProtein (Globulin)HazelnutCorylus avellanaNut KernelModerateA nut storage protein providing essential fatty acid-associated amino acids; may support brain function and metabolic health.
JuglansinWalnut 11S GlobulinProtein (Globulin)WalnutJuglans regiaNut KernelModerateProvides essential amino acids alongside heart-healthy fats; may support healthy aging and cognitive function.
CocosinCoconut GlobulinProtein (Globulin)CoconutCocos nuciferaEndospermModerateA coconut storage protein studied for its potential to support energy levels and healthy fat metabolism.
VigninMung Bean Globulin; 8S GlobulinProtein (Globulin)Mung BeanVigna radiataSeedModerateA highly digestible legume protein that may support muscle repair and is generally well-tolerated by the digestive system.
CicerinChickpea GlobulinProtein (Globulin)ChickpeaCicer arietinumSeedModerateA satiating plant protein that may support healthy weight management and appetite regulation.
LininFlaxseed GlobulinProtein (Globulin)FlaxseedLinum usitatissimumSeedModerateMay work synergistically with flaxseed's omega-3 fats to support heart health and hormonal balance.
ConglutinLupin Globulin; alpha-ConglutinProtein (Globulin)LupinLupinus spp.SeedModerateA high-protein legume fraction that may help support healthy post-meal blood sugar levels.
STORAGE PROTEINS — PROLAMINS
GliadinWheat Prolamin; alpha/beta/gamma-GliadinProtein (Prolamin)WheatTriticum aestivumGrain EndospermHighA wheat storage protein that provides dietary nitrogen; responsible for the viscoelastic properties of gluten. Note: implicated in coeliac disease in susceptible individuals.
GluteninHigh/Low MW Glutenin; HMW-GSProtein (Glutelin)WheatTriticum aestivumGrain EndospermHighThe glutelin fraction of gluten that contributes to dough strength; provides a structural protein matrix for sustained carbohydrate energy release.
ZeinCorn Prolamin; alpha/beta/gamma-ZeinProtein (Prolamin)Maize (Corn)Zea maysGrain EndospermModerateA gluten-free grain protein providing specific amino acid components for cellular energy production and structural support.
HordeinBarley Prolamin; B/C/D-HordeinProtein (Prolamin)BarleyHordeum vulgareGrain EndospermModerateA barley storage protein that contributes to metabolic support; may cause sensitivity in gluten-intolerant individuals.
SecalinRye Prolamin; gamma-SecalinProtein (Prolamin)RyeSecale cerealeGrain EndospermModerateA rye storage protein that contributes to dietary protein intake; may cause sensitivity in coeliac or gluten-sensitive individuals.
AveninOat ProlaminProtein (Prolamin)OatsAvena sativaGrain EndospermModerateA gentle, well-tolerated oat protein that may contribute to heart health and muscle recovery when consumed as part of a balanced diet.
KafirinSorghum Prolamin; alpha/beta-KafirinProtein (Prolamin)SorghumSorghum bicolorGrain EndospermModerateA gluten-free grain protein that provides a hypoallergenic protein source and may support healthy metabolic function.
STORAGE PROTEINS — GLUTELINS & ALBUMINS
OryzeninRice Glutelin; Rice ProteinProtein (Glutelin)RiceOryza sativaGrain EndospermModerateA hypoallergenic, easily digestible plant protein that may support muscle maintenance without triggering common grain allergies.
Napin2S Albumin; Rapeseed 2SProtein (Albumin)Rapeseed / CanolaBrassica napusSeedModerateA sulfur-rich small storage protein; may provide cysteine and methionine for healthy skin, hair, and antioxidant defence.
LunasinBioactive Soy Peptide; 2S Albumin fragmentProtein (Albumin)SoybeanGlycine maxSeedModerateA bioactive peptide studied for potential anti-inflammatory properties and support of healthy cell cycle regulation.
LeukosinWheat Albumin; WGA-relatedProtein (Albumin)WheatTriticum aestivumGrainModerateA water-soluble wheat protein that contributes to the overall nutritional value of whole-wheat foods.
LegumelinSoy Albumin fractionProtein (Albumin)SoybeanGlycine maxSeedModerateSupplies essential amino acids for daily cellular repair and growth as part of a complete plant protein diet.
LECTINS
Concanavalin ACon A; Jack Bean LectinProtein (Lectin)Jack BeanCanavalia ensiformisSeedModerateA well-characterised mitogenic lectin widely used in immunological research to study T-cell activation and immune surveillance.
Wheat Germ AgglutininWGAProtein (Lectin)WheatTriticum aestivumGermModerateA chitin-binding lectin studied for its interaction with gut epithelial surfaces; subject of ongoing research into digestive health effects.
PROTEASE ENZYMES (HYDROLASES)
PapainPapaya Protease; EC 3.4.22.2Enzyme (Hydrolase / Protease)PapayaCarica papayaFruit (Latex)HighEffectively breaks down dietary proteins to support comfortable digestion; may help reduce post-meal bloating and digestive discomfort.
BromelainPineapple Protease; EC 3.4.22.32Enzyme (Hydrolase / Protease)PineappleAnanas comosusFruit and StemHighMay support reduction of localised swelling and discomfort; studied for its role in aiding digestion of protein-rich foods.
ActinidinKiwifruit Protease; EC 3.4.22.14Enzyme (Hydrolase / Protease)KiwifruitActinidia deliciosaFruitModerateStudied for its ability to specifically improve digestion of proteins from meat, eggs, and dairy, potentially improving gut comfort.
FicinFig Protease; EC 3.4.22.3Enzyme (Hydrolase / Protease)FigFicus caricaFruit (Latex)ModerateA plant cysteine protease that may aid in protein digestion and has been studied for potential soothing effects in the gut.
CARBOHYDRASE ENZYMES (HYDROLASES)
Alpha-Amylase1,4-alpha-D-glucan glucanohydrolase; EC 3.2.1.1Enzyme (Hydrolase / Carbohydrase)MangoMangifera indicaFruitHighCatalyses the hydrolysis of dietary starch into shorter oligosaccharides, supporting efficient carbohydrate digestion and energy availability.
Beta-Amylase1,4-alpha-D-glucan maltohydrolase; EC 3.2.1.2Enzyme (Hydrolase / Carbohydrase)Sweet PotatoIpomoea batatasTuberModerateSlowly releases maltose from starch; may support a more gradual and sustained release of glucose into the bloodstream.
CellulaseEC 3.2.1.4Enzyme (Hydrolase / Carbohydrase)SproutsMedicago sativaWhole SproutModerateMay assist in breaking down plant cell wall fibers, potentially reducing bloating and improving regularity.
InvertaseBeta-fructofuranosidase; EC 3.2.1.26Enzyme (Hydrolase / Carbohydrase)Honey (via Pollen)Pollen / NectarModerateConverts sucrose into glucose and fructose, providing rapidly available cellular energy.
PectinasePolygalacturonase (class); EC 3.2.1.15Enzyme (Hydrolase / Carbohydrase)AppleMalus domesticaFruitModerateBreaks down pectin in plant cell walls; may improve bioavailability of vitamins and minerals from plant foods.
MaltaseAlpha-glucosidase; EC 3.2.1.20Enzyme (Hydrolase / Carbohydrase)BananaMusa acuminataFruitHighCompletes the digestion of maltose into glucose at the intestinal brush border, supporting steady energy supply.
SucraseBeta-fructosidase; EC 3.2.1.48Enzyme (Hydrolase / Carbohydrase)SugarcaneSaccharum officinarumStem JuiceHighHydrolyses dietary sucrose to glucose and fructose; essential for normal carbohydrate digestion and energy metabolism.
Alpha-GalactosidaseEC 3.2.1.22Enzyme (Hydrolase / Carbohydrase)BeansPhaseolus spp.SeedModerateMay reduce the production of gas and bloating from consuming high-fiber legumes by breaking down indigestible oligosaccharides.
Beta-GlucosidaseEC 3.2.1.21Enzyme (Hydrolase / Carbohydrase)AlmondsPrunus dulcisNutModerateUnlocks bioactive aglycone compounds from plant glycosides, potentially improving their availability for health support.
GlucanaseEC 3.2.1.6Enzyme (Hydrolase / Carbohydrase)BarleyHordeum vulgareGrainModerateBreaks down beta-glucan fibers; may support the release of heart-healthy fiber fractions from cereal grains.
XylanaseEC 3.2.1.8Enzyme (Hydrolase / Carbohydrase)Oat BranAvena sativaGrainModerateMay aid in the breakdown of tough hemicellulose fibers from whole grains, improving digestive comfort.
HemicellulaseEC 3.2.1 (class)Enzyme (Hydrolase / Carbohydrase)Whole GrainsVariousSeed CoatModerateBreaks down complex hemicellulose polysaccharides to release prebiotic fragments that feed beneficial gut bacteria.
Alpha-GlucosidaseEC 3.2.1.20Enzyme (Hydrolase / Carbohydrase)BuckwheatFagopyrum esculentumSeedModeratePlays a key role in the final hydrolysis of starch at the intestinal surface; inhibition of this enzyme is a studied approach to blood sugar management.
PolygalacturonaseEC 3.2.1.15Enzyme (Hydrolase / Carbohydrase)TomatoSolanum lycopersicumFruitModerateA fruit-ripening enzyme that breaks down pectin, improving the bioavailability of antioxidants and beneficial plant pigments.
Pectin MethylesteraseEC 3.1.1.11Enzyme (Hydrolase / Carbohydrase)OrangeCitrus sinensisFruitModerateWorks alongside pectinase to support the healthy breakdown of fruit fiber; may contribute to normal digestive tract function.
MyrosinaseThioglucosidase; EC 3.2.1.147Enzyme (Hydrolase / Carbohydrase)BroccoliBrassica oleraceaFloretsHighActivates glucosinolate hydrolysis to produce bioactive compounds including sulforaphane; requires intact plant tissue for activity.
LactaseBeta-galactosidase; EC 3.2.1.23Enzyme (Hydrolase / Carbohydrase)Fermented SoyGlycine maxBean (Fermented)HighHydrolyses lactose into glucose and galactose; supplementation may support digestive comfort in lactose-sensitive individuals.
PhytaseEC 3.1.3.8Enzyme (Hydrolase / Carbohydrase)Wheat BranTriticum aestivumOuter LayerModerateHydrolyses phytic acid in cereal grains, potentially improving the bioavailability of minerals such as iron, zinc, and calcium.
UreaseEC 3.5.1.5Enzyme (Hydrolase)Jack BeanCanavalia ensiformisSeedModerateCatalyses the hydrolysis of urea; studied for its role in nitrogen metabolism and efficient protein utilisation.
AsparaginaseL-Asparaginase; EC 3.5.1.1Enzyme (Hydrolase)AsparagusAsparagus officinalisSpearsModerateBreaks down asparagine in plant foods; studied for its role in supporting healthy cell cycle dynamics.
ArginaseEC 3.5.3.1Enzyme (Hydrolase)SoybeanGlycine maxSeedModerateCatalyses the final step of the urea cycle, helping the liver process nitrogen waste from dietary protein.
LIPASE ENZYMES (HYDROLASES)
LipaseTriacylglycerol lipase; EC 3.1.1.3Enzyme (Hydrolase / Lipase)AvocadoPersea americanaFruitHighCatalyses the hydrolysis of dietary fats into fatty acids and glycerol, supporting absorption of fat-soluble vitamins and essential fats.
OXIDOREDUCTASE ENZYMES
Superoxide DismutaseSOD; EC 1.15.1.1Enzyme (Oxidoreductase)WheatgrassTriticum aestivumYoung LeavesHighA primary cellular antioxidant enzyme that dismutates superoxide radicals; studied for its role in supporting healthy aging and oxidative stress management.
CatalaseEC 1.11.1.6Enzyme (Oxidoreductase)PotatoSolanum tuberosumTuberHighNeutralises hydrogen peroxide produced in metabolic processes, protecting cells and tissues from oxidative damage.
PeroxidaseEC 1.11.1Enzyme (Oxidoreductase)HorseradishArmoracia rusticanaRootModerateSupports the body's oxidative defence pathways; studied for its role in detoxification and immune system function.
Polyphenol OxidasePPO; Tyrosinase (plant); EC 1.10.3.1Enzyme (Oxidoreductase)BananaMusa acuminataFruitModerateInvolved in phenolic compound oxidation during ripening; studied for its role in making antioxidant plant compounds more bioavailable.
LipoxygenaseLOX; EC 1.13.11.12Enzyme (Oxidoreductase)SoybeanGlycine maxSeedModerateMetabolises polyunsaturated fatty acids to produce oxylipins; plays a regulatory role in cell membrane integrity and inflammatory balance.
Ascorbate PeroxidaseAPX; EC 1.11.1.11Enzyme (Oxidoreductase)SpinachSpinacia oleraceaLeavesModerateWorks in concert with Vitamin C to neutralise hydrogen peroxide; may contribute to the antioxidant capacity of green leafy vegetable consumption.
Glucose OxidaseGOx; EC 1.1.3.4Enzyme (Oxidoreductase)Honey (via Nectar)NectarModerateProduces hydrogen peroxide as a by-product; studied for its potential contribution to maintaining a healthy microbial balance in fermented foods.
Glutathione PeroxidaseGPx; EC 1.11.1.9Enzyme (Oxidoreductase)GarlicAllium sativumBulbHighA selenium-dependent antioxidant enzyme that protects cells from lipid peroxidation and supports healthy detoxification of heavy metals.
Ascorbate OxidaseEC 1.10.3.3Enzyme (Oxidoreductase)CucumberCucumis sativusFruitModerateRegulates the oxidation state of ascorbic acid in plant tissues; studied for its interaction with Vitamin C metabolism.
TyrosinaseEC 1.14.18.1Enzyme (Oxidoreductase)Button MushroomAgaricus bisporusFruit BodyModerateInvolved in melanin biosynthesis and phenolic compound processing; studied for its role in skin health and general metabolic regulation.
NitrogenaseEC 1.18.6.1Enzyme (Oxidoreductase)PeasPisum sativumRootsHighThe enzyme responsible for biological nitrogen fixation in legume root nodules; the foundational source of bioavailable nitrogen in plant-based protein foods.
Lactate DehydrogenaseLDH; EC 1.1.1.27Enzyme (Oxidoreductase)PeasPisum sativumSeedModerateInterconverts lactate and pyruvate; studied for its role in supporting muscle endurance and anaerobic energy metabolism.
Malate DehydrogenaseMDH; EC 1.1.1.37Enzyme (Oxidoreductase)AppleMalus domesticaFruitModerateA key enzyme of the citric acid cycle linking malate and oxaloacetate; central to maintaining cellular energy production.
Succinate DehydrogenaseSDH; EC 1.3.5.1Enzyme (Oxidoreductase)MilletPanicum miliaceumSeedModerateA membrane-bound enzyme at the intersection of the citric acid cycle and the electron transport chain; important for efficient mitochondrial energy generation.
Alcohol DehydrogenaseADH; EC 1.1.1.1Enzyme (Oxidoreductase)OrangeCitrus sinensisFruitModerateCatalyses the interconversion of alcohols and aldehydes; plays a role in the detoxification of naturally occurring organic compounds.
Glutamate DehydrogenaseGDH; EC 1.4.1.2Enzyme (Oxidoreductase)PeanutsArachis hypogaeaSeedModeratePlays a central role in amino acid catabolism and the integration of protein and carbohydrate metabolism for energy balance.
Nitrate ReductaseNR; EC 1.7.1.1Enzyme (Oxidoreductase)BeetrootBeta vulgarisRootModerateReduces dietary nitrate to nitrite, which the body further converts to nitric oxide; may support healthy blood pressure and circulation.
Glyceraldehyde-3-P DehydrogenaseGAPDH; EC 1.2.1.12Enzyme (Oxidoreductase)KaleBrassica oleraceaLeavesHighA central glycolytic enzyme that catalyses the conversion of glyceraldehyde-3-phosphate and directly releases energy from dietary sugars.
Malic EnzymeME; EC 1.1.1.40Enzyme (Oxidoreductase)AppleMalus domesticaFruitModerateCatalyses the oxidative decarboxylation of malate; studied for its role in supporting the biosynthesis of healthy fats and NADPH generation.
Glutathione ReductaseGR; EC 1.8.1.7Enzyme (Oxidoreductase)SpinachSpinacia oleraceaLeavesHighRegenerates reduced glutathione from its oxidised form, maintaining the body's primary antioxidant defence and cellular redox balance.
Thioredoxin ReductaseTrxR; EC 1.8.1.9Enzyme (Oxidoreductase)Wheat GermTriticum aestivumGermModerateMaintains the thioredoxin system, which plays a key role in DNA repair, antioxidant defence, and cellular stress responses.
Homoserine DehydrogenaseEC 1.1.1.3Enzyme (Oxidoreductase)BarleyHordeum vulgareGrainModerateAn enzyme in the aspartate family amino acid biosynthesis pathway; studied as an essential contributor to the production of amino acids required for tissue repair.
Omega-3 DesaturaseFAD3; EC 1.14.19.25Enzyme (Oxidoreductase)Chia SeedsSalvia hispanicaSeedModerateIntroduces the omega-3 double bond into linoleic acid; the key enzyme determining ALA content in flaxseed, chia, and other plant omega-3 sources.
Sarcosine OxidaseEC 1.5.3.1Enzyme (Oxidoreductase)Wheat BranTriticum aestivumOuter LayerEmergingStudied for its role in amino acid catabolism and maintaining efficient metabolic clearance of certain nitrogen-containing compounds.
L-Amino Acid OxidaseLAAO; EC 1.4.3.2Enzyme (Oxidoreductase)PeasPisum sativumSeedEmergingStudied for its role in amino acid catabolism and its antimicrobial properties in plant defence systems.
Urate OxidaseUricase; EC 1.7.3.3Enzyme (Oxidoreductase)SoybeanGlycine maxSeedModerateCatalyses the oxidation of uric acid; studied for its potential to support healthy uric acid balance and joint function.
Xanthine OxidaseXO; EC 1.17.3.2Enzyme (Oxidoreductase)Milk ThistleSilybum marianumSeedModerateInvolved in purine catabolism; studied in the context of uric acid management and its relationship to healthy blood chemistry.
Cytochrome c ReductaseEC 1.6.99.3Enzyme (Oxidoreductase)SpinachSpinacia oleraceaLeavesModerateA component of the mitochondrial electron transport chain; essential for efficient cellular energy transfer and ATP production.
LYASE ENZYMES
Phenylalanine Ammonia-LyasePAL; EC 4.3.1.24Enzyme (Lyase)StrawberryFragaria ananassaFruitModerateA key enzyme initiating the phenylpropanoid pathway; triggers the production of plant polyphenols and antioxidants relevant to cardiovascular health.
AldolaseFructose-1,6-bisphosphate aldolase; EC 4.1.2.13Enzyme (Lyase)PeasPisum sativumSeedHighA central glycolytic enzyme that cleaves fructose-1,6-bisphosphate, enabling the efficient conversion of dietary sugars into cellular energy.
Pyruvate DecarboxylasePDC; EC 4.1.1.1Enzyme (Lyase)GrapesVitis viniferaFruitModerateConverts pyruvate to acetaldehyde during anaerobic fermentation; studied in the context of producing fermented plant foods that support gut wellness.
Carbonic AnhydraseCA; EC 4.2.1.1Enzyme (Lyase)KaleBrassica oleraceaLeavesHighCatalyses the reversible hydration of CO2; essential for maintaining the acid-base balance of blood and efficient respiratory gas exchange.
Terpene SynthaseTPS; EC 4.2.3 (class)Enzyme (Lyase)PeppermintMentha piperitaLeavesModerateProduces plant terpenoid compounds including menthol and limonene; the source enzyme for aromatic botanical extracts studied for digestive and respiratory comfort.
AlliinaseAlliin lyase; EC 4.4.1.4Enzyme (Lyase)GarlicAllium sativumBulbHighConverts alliin to allicin when garlic tissue is disrupted; activates the primary heart-health and antimicrobial compounds in garlic.
EnolasePhosphopyruvate hydratase; EC 4.2.1.11Enzyme (Lyase)PotatoSolanum tuberosumTuberHighA key glycolytic enzyme that catalyses the penultimate step of glycolysis, contributing directly to cellular energy production.
FumaraseFumarate hydratase; EC 4.2.1.2Enzyme (Lyase)Citrus FruitsCitrus spp.FruitHighCatalyses the reversible hydration of fumarate to malate in the citric acid cycle; essential for continuous cellular energy production.
Cysteine SynthaseO-acetylserine sulfhydrylase; EC 2.5.1.47Enzyme (Lyase)OnionsAllium cepaBulbModerateSynthesises the amino acid cysteine, which is essential for glutathione production, liver detoxification, and healthy hair and skin.
Ornithine DecarboxylaseODC; EC 4.1.1.17Enzyme (Lyase)TomatoSolanum lycopersicumFruitModerateCatalyses the first step of polyamine biosynthesis; polyamines play a fundamental role in the rapid repair and growth of body tissues.
Arginine DecarboxylaseADC; EC 4.1.1.19Enzyme (Lyase)OatsAvena sativaGrainModerateProduces agmatine and other polyamine precursors; studied for their potential role in supporting the body's resilience to metabolic stress.
Threonine DehydrataseEC 4.3.1.19Enzyme (Lyase)SoybeanGlycine maxSeedModerateConverts threonine to alpha-ketobutyrate for energy; contributes to the efficient use of amino acids during periods of elevated energy demand.
Threonine SynthaseTS; EC 4.2.3.1Enzyme (Lyase)OatsAvena sativaGrainModerateSynthesises the essential amino acid threonine from homoserine phosphate; contributes to the amino acid completeness of oat-based protein.
Cystathionine Beta-LyaseCBL; EC 4.4.1.8Enzyme (Lyase)BroccoliBrassica oleraceaFlower BudsModerateParticipates in the sulfur amino acid metabolism pathway; studied for its contribution to healthy liver sulfur cycle function.
TRANSFERASE ENZYMES
HexokinaseHK; EC 2.7.1.1Enzyme (Transferase)WheatTriticum aestivumGrainHighPhosphorylates glucose as the first committed step of glycolysis; the rate-limiting entry point for dietary glucose into cellular energy metabolism.
Pyruvate KinasePK; EC 2.7.1.40Enzyme (Transferase)PotatoSolanum tuberosumTuberHighCatalyses the final ATP-generating step of glycolysis; essential for the efficient conversion of food into energy to sustain physical activity.
Phosphoglycerate KinasePGK; EC 2.7.2.3Enzyme (Transferase)SpinachSpinacia oleraceaLeavesHighGenerates ATP directly from dietary carbohydrate breakdown; a primary energy-yielding step in glycolysis used by all cells.
Glutathione S-TransferaseGST; EC 2.5.1.18Enzyme (Transferase)CabbageBrassica oleraceaLeavesHighConjugates glutathione to electrophilic compounds; plays a central role in the liver's detoxification of potentially harmful dietary and environmental chemicals.
HexokinaseGlucokinase (Liver); EC 2.7.1.2Enzyme (Transferase)RiceOryza sativaGrainHighActs as a glucose sensor in hepatocytes; helps the body maintain a healthy blood sugar response after carbohydrate-containing meals.
FructokinaseKetohexokinase; EC 2.7.1.4Enzyme (Transferase)TomatoSolanum lycopersicumFruitModeratePhosphorylates dietary fructose specifically in the liver; studied in the context of understanding healthy fructose metabolism and metabolic balance.
PhosphofructokinasePFK; EC 2.7.1.11Enzyme (Transferase)Sweet PotatoIpomoea batatasTuberHighA master regulatory enzyme of glycolysis that controls the rate of glucose breakdown; central to matching energy supply with physical demand.
UDP-Glucose PyrophosphorylaseUGPase; EC 2.7.7.9Enzyme (Transferase)RiceOryza sativaGrainModerateSynthesises UDP-glucose, the activated sugar donor used for glycogen and cellulose biosynthesis, supporting healthy energy storage between meals.
Branching EnzymeStarch Branching Enzyme; EC 2.4.1.18Enzyme (Transferase)PotatoSolanum tuberosumTuberModerateCreates branch points in starch and glycogen molecules; influences the digestibility of starch and the production of resistant starch fractions that feed gut bacteria.
S-Adenosylmethionine SynthetaseSAM Synthetase; EC 2.5.1.6Enzyme (Transferase)GarlicAllium sativumBulbModerateSynthesises SAM, the primary methyl donor in the body; supports liver health, mood-related neurotransmitter synthesis, and the production of sulfur-containing wellness compounds.
GlycosyltransferaseGT; EC 2.4 (class)Enzyme (Transferase)SteviaStevia rebaudianaLeavesModerateA large enzyme family responsible for attaching sugar groups to plant compounds; the enzymes that produce steviol glycosides, the naturally sweet compounds in stevia.
MethyltransferaseMT; EC 2.1.1 (class)Enzyme (Transferase)BeetrootBeta vulgarisRootModerateCatalyses the transfer of methyl groups to a wide range of biological targets; plays a broad role in liver detoxification, DNA methylation, and energy metabolism.
Citrate SynthaseCS; EC 2.3.3.1Enzyme (Transferase)LemonCitrus limonFruitHighCatalyses the entry of acetyl-CoA into the citric acid cycle; the rate-controlling 'spark' that initiates cellular energy production from food.
Alanine AminotransferaseALT; EC 2.6.1.2Enzyme (Transferase)Green Leafy VegVariousLeavesModerateInterconverts alanine and pyruvate; a key enzyme for converting amino acids into energy and maintaining healthy liver metabolic function.
Aspartate AminotransferaseAST; EC 2.6.1.1Enzyme (Transferase)Root VegetablesVariousRootsModerateLinks amino acid and carbohydrate metabolism; essential for ensuring continuous energy availability in heart and liver cells.
Branched-Chain AminotransferaseBCAT; EC 2.6.1.42Enzyme (Transferase)Garden PeasPisum sativumSeedModerateCatalyses the first step in the catabolism of branched-chain amino acids (leucine, isoleucine, valine); studied for its role in muscle protein synthesis and recovery.
Glycine HydroxymethyltransferaseSHMT; EC 2.1.2.1Enzyme (Transferase)RiceOryza sativaGrainModerateInterconverts glycine and serine while transferring one-carbon units; essential for folate metabolism and healthy DNA synthesis.
Serine HydroxymethyltransferaseSHMT; EC 2.1.2.1Enzyme (Transferase)SpinachSpinacia oleraceaLeavesModerateA central enzyme linking amino acid metabolism to folate-dependent one-carbon metabolism; essential for healthy cell replication.
Methionine SynthaseMS; EC 2.1.1.13Enzyme (Transferase)LentilsLens culinarisSeedModerateRegenerates methionine from homocysteine using folate and B12; studied for its role in maintaining healthy homocysteine levels as a cardiovascular marker.
Spermidine SynthaseSpdS; EC 2.5.1.16Enzyme (Transferase)Wheat GermTriticum aestivumGermModerateSynthesises spermidine, a polyamine associated with cellular autophagy and longevity signalling; studied in the context of healthy aging.
Betaine-Homocysteine MethyltransferaseBHMT; EC 2.1.1.5Enzyme (Transferase)BeetrootBeta vulgarisRootModerateConverts homocysteine to methionine using betaine; may support healthy cardiovascular function by contributing to normal homocysteine balance.
Phytoene SynthasePSY; EC 2.5.1.32Enzyme (Transferase)CarrotDaucus carotaRootModerateCatalyses the first committed step of carotenoid biosynthesis; the enzyme that initiates the production of beta-carotene and the provitamin A found in colourful plants.
Lycopene Beta-CyclaseLYCB; EC 5.5.1.19Enzyme (Isomerase)PumpkinCucurbita maximaFruitModerateConverts the linear carotenoid lycopene into cyclic beta-carotene; the enzyme responsible for producing Vitamin A precursors from plant pigments.
ThiolaseAcetyl-CoA acetyltransferase; EC 2.3.1.9Enzyme (Transferase)Sunflower SeedsHelianthus annuusSeedModerateCatalyses the thiolytic cleavage of acetoacetyl-CoA; plays a key role in fatty acid beta-oxidation and healthy fat-derived energy production.
Beta-Ketoacyl-ACP SynthaseKAS; EC 2.3.1.41Enzyme (Transferase)CoconutCocos nuciferaEndospermModerateA key enzyme in de novo fatty acid synthesis; determines the chain length and type of fatty acids produced in plant seeds.
Glycerol-3-Phosphate AcyltransferaseGPAT; EC 2.3.1.15Enzyme (Transferase)AvocadoPersea americanaFruitModerateCatalyses the first step in glycerolipid biosynthesis; essential for building the structural phospholipids that comprise every human cell membrane.
Malate SynthaseMS; EC 2.3.3.9Enzyme (Transferase)Sunflower SeedsHelianthus annuusSeedModerateA glyoxylate cycle enzyme that converts acetyl-CoA and glyoxylate to malate; studied for its role in the efficient conversion of stored fats to cellular energy.
Creatine KinaseCK; EC 2.7.3.2Enzyme (Transferase)Whole GrainsVariousGrainModerateCatalyses the transfer of a phosphate group to ADP to regenerate ATP; plays a central role in the rapid energy demands of muscle and nerve tissues.
Adenylate KinaseAK; EC 2.7.4.3Enzyme (Transferase)SpinachSpinacia oleraceaLeavesModerateMaintains the cellular energy charge by interconverting ATP, ADP, and AMP; acts as a sensitive sensor and regulator of cellular energy status.
Nucleoside-Diphosphate KinaseNDPK; EC 2.7.4.6Enzyme (Transferase)KaleBrassica oleraceaLeavesModerateSynthesises nucleoside triphosphates from ATP; provides the activated nucleotide building blocks required for DNA and RNA repair and synthesis.
RNA PolymeraseRNAP; EC 2.7.7.6Enzyme (Transferase)Rice GermOryza sativaGermHighTranscribes DNA into RNA; the fundamental enzyme required for the expression of all genetic information and the production of proteins.
Ornithine CarbamoyltransferaseOTC; EC 2.1.3.3Enzyme (Transferase)PeanutsArachis hypogaeaSeedModerateA central enzyme of the urea cycle that helps the liver safely convert protein-derived ammonia into urea for excretion.
PhosphoglucoisomerasePGI; EC 5.3.1.9Enzyme (Isomerase)CornZea maysGrainHighInterconverts glucose-6-phosphate and fructose-6-phosphate; an essential step in glycolysis for converting dietary glucose into usable cellular fuel.
ISOMERASE ENZYMES
Glucose IsomeraseXylose isomerase; EC 5.3.1.5Enzyme (Isomerase)BarleyHordeum vulgareGrainModerateInterconverts glucose and fructose; widely used in the food industry and studied for its role in balanced dietary sugar management.
Triose Phosphate IsomeraseTPI; EC 5.3.1.1Enzyme (Isomerase)SpinachSpinacia oleraceaLeavesHighInterconverts the two triose phosphate intermediates of glycolysis; essential for the efficient extraction of energy from every glucose molecule.
EpimeraseUDP-glucose 4-epimerase; EC 5.1.3.2Enzyme (Isomerase)SoybeanGlycine maxSeedModerateInterconverts UDP-glucose and UDP-galactose; essential for the body's biosynthesis of glycoproteins and cell membrane glycolipids.
RacemaseAlanine racemase; EC 5.1.1.1Enzyme (Isomerase)AlfalfaMedicago sativaLeavesModerateInterconverts L- and D-amino acids; studied for its role in the proper formation of structural proteins and supporting a healthy gut microbiome.
LIGASE ENZYMES
DNA LigaseEC 6.5.1.1Enzyme (Ligase)Broccoli SproutsBrassica oleraceaWhole SproutHighCatalyses the joining of DNA strand breaks; an essential enzyme for the faithful repair and replication of the human genome.
Glutamine SynthetaseGS; EC 6.3.1.2Enzyme (Ligase)PeanutsArachis hypogaeaSeedHighSynthesises glutamine from glutamate and ammonia; glutamine is the primary fuel for immune cells and a key molecule for maintaining gut lining integrity.
Acetyl-CoA CarboxylaseACC; EC 6.4.1.2Enzyme (Ligase)SunflowerHelianthus annuusSeedModerateCatalyses the rate-limiting step in de novo fatty acid synthesis; determines the body's capacity to produce healthy structural and regulatory fats.
Pyruvate CarboxylasePC; EC 6.4.1.1Enzyme (Ligase)SoybeanGlycine maxSeedModerateConverts pyruvate to oxaloacetate, replenishing the citric acid cycle; essential for maintaining the steady supply of energy in heart and brain tissues.
S-Adenosylmethionine SynthetaseMAT; EC 2.5.1.6Enzyme (Ligase)GarlicAllium sativumBulbModerateSynthesises SAM from methionine and ATP; SAM is the universal methyl donor supporting mood-related neurotransmitter synthesis and liver function.
Leucyl-tRNA SynthetaseLeuRS; EC 6.1.1.4Enzyme (Ligase)Pumpkin SeedsCucurbita pepoSeedModerateAminoacylates leucine onto its cognate tRNA; plays a role in nutrient sensing and has been studied as an activator of the mTOR pathway regulating muscle protein synthesis.
Tryptophanyl-tRNA SynthetaseTrpRS; EC 6.1.1.2Enzyme (Ligase)Chia SeedsSalvia hispanicaSeedModerateEnsures tryptophan is correctly incorporated during protein synthesis; studied for its connection to the production of serotonin and sleep-supporting melatonin.
Lysine-tRNA LigaseLysRS; EC 6.1.1.6Enzyme (Ligase)QuinoaChenopodium quinoaSeedModerateEnsures the accurate incorporation of lysine into proteins; lysine is an essential amino acid critical for collagen synthesis and tissue repair.
Tyrosine-tRNA LigaseTyrRS; EC 6.1.1.1Enzyme (Ligase)Pumpkin SeedsCucurbita pepoSeedModerateEnsures tyrosine is correctly incorporated during protein synthesis; studied for its links to neurotransmitter and thyroid hormone production.
Valine-tRNA LigaseValRS; EC 6.1.1.9Enzyme (Ligase)LentilsLens culinarisSeedModerateRequired for the correct incorporation of valine into proteins; valine is a branched-chain amino acid important for muscle repair and recovery.
Histidine-tRNA LigaseHisRS; EC 6.1.1.21Enzyme (Ligase)PeanutsArachis hypogaeaSeedModerateEnsures histidine is correctly incorporated during protein synthesis; studied for its connection to the production of histamine and the body's inflammatory response.
Carbamoyl Phosphate SynthetaseCPS; EC 6.3.4.16Enzyme (Ligase)Sunflower SeedsHelianthus annuusSeedModerateInitiates the urea cycle by synthesising carbamoyl phosphate; essential for the liver's safe disposal of excess dietary protein nitrogen.
MULTI-FUNCTIONAL / COMPLEX PROTEINS
RuBisCoRibulose-1,5-bisphosphate carboxylase/oxygenase; EC 4.1.1.39Protein / EnzymeSpinachSpinacia oleraceaLeavesModerateThe most abundant protein on Earth; provides a nutritionally complete amino acid profile when consumed as a leaf protein concentrate, with emerging interest as a sustainable plant protein source.
RibonucleaseRNase; EC 3.1.26.4Enzyme (Hydrolase)SpinachSpinacia oleraceaLeavesModerateCatalyses the degradation of RNA; involved in cellular RNA turnover and the recycling of nucleotide building blocks.
DeoxyribonucleaseDNase; EC 3.1.21.1Enzyme (Hydrolase)TomatoSolanum lycopersicumFruitModerateCatalyses the hydrolysis of DNA; plays a housekeeping role in the safe recycling of genetic material within tissues.
GlutaminaseGLS; EC 3.5.1.2Enzyme (Hydrolase)MisoGlycine maxFermented BeanModerateConverts glutamine to glutamate; releases flavour-active amino acids in fermented plant foods and produces glutamate as fuel for rapidly dividing immune and gut cells.
Alpha-MannosidaseEC 3.2.1.24Enzyme (Hydrolase)Jack BeanCanavalia ensiformisSeedModerateRemoves mannose residues from glycoproteins during their maturation; essential for the correct folding and quality control of secreted proteins.
Beta-MannosidaseEC 3.2.1.25Enzyme (Hydrolase)Guar BeanCyamopsis tetragonolobaSeedModerateHydrolyses terminal mannose residues from galactomannans; studied for its contribution to fiber digestion and healthy blood cholesterol management.
Leucine AminopeptidaseLAP; EC 3.4.11.1Enzyme (Hydrolase)BarleyHordeum vulgareGrainModerateCleaves N-terminal amino acids from peptide chains; supports the final stages of protein digestion for maximum nutrient absorption.
CarboxypeptidaseEC 3.4.17 (class)Enzyme (Hydrolase)SoybeanGlycine maxSeedModerateRemoves amino acids from the C-terminus of peptides; assists in the complete breakdown of dietary protein into absorbable amino acids.
AminopeptidaseEC 3.4.11 (class)Enzyme (Hydrolase)Cereal GrainsVariousGermModerateCleaves single amino acids from the N-terminus of peptide chains, completing the digestion of dietary proteins for direct absorption.
Adenosine DeaminaseADA; EC 3.5.4.4Enzyme (Hydrolase)PotatoSolanum tuberosumTuberModerateCatalyses the deamination of adenosine in the purine salvage pathway; a critical enzyme for normal T-cell immune function and healthy cellular communication.
GlucokinaseHexokinase IV; EC 2.7.1.2Enzyme (Transferase)RiceOryza sativaGrainModerateFunctions as a hepatic glucose sensor that helps regulate insulin secretion; studied for its central role in maintaining healthy post-meal blood sugar balance.
VITAMIN C
Vitamin CCAS 50-81-7Ascorbic acid; L-Ascorbic acid; E300Vitamins (Vitamin C)Rose HipsRosa caninaFruitHighA well-validated water-soluble antioxidant essential for normal immune function, collagen synthesis, and iron absorption from plant foods.
PROVITAMIN A CAROTENOIDS
Beta-caroteneCAS 7235-40-7Provitamin A; beta,beta-CaroteneVitamins (Provitamin A Carotenoid)CarrotDaucus carotaRootHighA provitamin A carotenoid converted by the body to retinol as needed; supports healthy vision, normal immune function, and skin integrity.
Alpha-caroteneCAS 7488-99-5alpha,beta-CaroteneVitamins (Provitamin A Carotenoid)PumpkinCucurbita maximaFruitModerateA provitamin A carotenoid with roughly half the conversion efficiency of beta-carotene; may contribute to healthy cell growth and immune defence.
Beta-cryptoxanthinCAS 472-70-8beta-Cryptoxanthin; CryptoxanthinVitamins (Provitamin A Carotenoid)PapayaCarica papayaFruitModerateA xanthophyll provitamin A that may be specifically supportive of lung and respiratory cell health, in addition to general vitamin A functions.
CAROTENOIDS — NON-PROVITAMIN A
LuteinCAS 127-40-2Xanthophyll; E161bVitamins (Carotenoid)KaleBrassica oleraceaLeavesHighAccumulates in the macular pigment of the eye; well-supported for reducing the risk of age-related macular degeneration and protecting against blue light stress.
ZeaxanthinCAS 144-68-3(3R,3'R)-Zeaxanthin; E161hVitamins (Carotenoid)Sweet CornZea maysGrainsHighA macular pigment carotenoid that may improve visual sharpness and help protect the retina from UV-induced oxidative damage.
LycopeneCAS 502-65-8Psi,psi-Carotene; E160dVitamins (Carotenoid)TomatoSolanum lycopersicumFruitHighA well-studied antioxidant carotenoid associated with cardiovascular health and potential skin photoprotection when consumed regularly as part of a varied diet.
PhytoeneCAS 542-42-77,8,11,12,7',8'-Hexahydro-lycopeneVitamins (Carotenoid)White TomatoSolanum lycopersicumFruitModerateA colourless carotenoid that may absorb UV light at the cellular level and contribute to overall skin antioxidant status.
PhytoflueneCAS 554-84-7Phytofluene; 7,8-Dihydro-zeta-caroteneVitamins (Carotenoid)TomatoSolanum lycopersicumFruitEmergingA colourless carotenoid studied in early-stage research for its potential role in complementing the photoprotective and antioxidant effects of other carotenoids.
AstaxanthinCAS 472-61-7(3S,3'S)-Astaxanthin; Haematococcus ExtractVitamins (Carotenoid)AlgaeHaematococcus pluvialisWhole CellHighA ketocarotenoid with exceptionally potent antioxidant activity; may support eye health, skin photoprotection, and exercise recovery when consumed regularly.
FucoxanthinCAS 3351-86-8(3S,5R,6S,3'S,5'R)-FucoxanthinVitamins (Carotenoid)KelpUndaria pinnatifidaWhole PlantModerateA marine carotenoid found in edible seaweeds; may support healthy metabolic rate and contribute to weight management when consumed as part of a balanced diet.
CapsanthinCAS 465-42-9(3R,3'S,5'R)-CapsanthinVitamins (Carotenoid)Red PepperCapsicum annuumFruitModerateA xanthophyll carotenoid unique to Capsicum; studied for its potential to contribute to a healthy lipid profile and support eye function.
NeoxanthinCAS 14646-79-8(3S,5R,6R,3'S,5'R,6'S)-NeoxanthinVitamins (Carotenoid)SpinachSpinacia oleraceaLeavesModerateA minor dietary xanthophyll studied for its potential antioxidant and metabolic balance-supporting properties.
ViolaxanthinCAS 126-29-4Zeaxanthin diepoxideVitamins (Carotenoid)Yellow PepperCapsicum annuumFruitModerateA plant xanthophyll studied for its antioxidant potential and contribution to the diverse carotenoid intake from colourful vegetables.
VITAMIN E — TOCOPHEROLS
Alpha-tocopherolCAS 59-02-9RRR-alpha-Tocopherol; Vitamin E; E307Vitamins (Vitamin E / Tocopherol)Wheat GermTriticum aestivumGermHighThe most biologically active form of Vitamin E; protects cell membranes from oxidative damage and supports normal immune function.
Gamma-tocopherolCAS 54-28-4gamma-TocopherolVitamins (Vitamin E / Tocopherol)WalnutJuglans regiaNut KernelModerateMay provide complementary anti-inflammatory protection to alpha-tocopherol; studied for its ability to neutralise reactive nitrogen species in tissues.
Delta-tocopherolCAS 119-13-1delta-TocopherolVitamins (Vitamin E / Tocopherol)Soybean OilGlycine maxSeed OilModerateA potent antioxidant tocopherol isomer studied for its potential contribution to maintaining the stability of cell membrane lipids.
Beta-tocopherolCAS 16698-35-4beta-TocopherolVitamins (Vitamin E / Tocopherol)Various GrainsSeedModerateA minor tocopherol isomer that may contribute to the overall protective antioxidant activity of mixed Vitamin E complexes.
VITAMIN E — TOCOTRIENOLS
Alpha-tocotrienolCAS 58864-81-6alpha-T3Vitamins (Vitamin E / Tocotrienol)Palm FruitElaeis guineensisFruitModerateA tocotrienol form of Vitamin E with greater membrane mobility than tocopherols; studied for its potential neuroprotective and cardioprotective properties.
Gamma-tocotrienolCAS 14101-61-2gamma-T3Vitamins (Vitamin E / Tocotrienol)Rice BranOryza sativaBranModerateStudied for its potential to support healthy cholesterol levels and provide antioxidant protection to cardiovascular tissues.
Delta-tocotrienolCAS 25612-59-3delta-T3Vitamins (Vitamin E / Tocotrienol)Annatto SeedsBixa orellanaSeedModerateThe predominant tocotrienol in annatto; studied for its potential contributions to long-term heart health and cellular antioxidant protection.
VITAMIN K
Vitamin K1CAS 84-80-0Phylloquinone; Phytonadione; K1Vitamins (Vitamin K)SpinachSpinacia oleraceaLeavesHighThe primary dietary form of Vitamin K from plants; essential for normal blood coagulation and for directing calcium to bones rather than soft tissues.
VITAMIN D
Vitamin D2CAS 50-14-6Ergocalciferol; Calciferol; E1141Vitamins (Vitamin D)UV-Exposed MushroomAgaricus bisporusFruiting BodyHighA plant-derived form of Vitamin D produced when mushrooms are exposed to UV light; may support bone mineralisation and healthy immune function, though D3 conversion efficiency is lower than solar D3.
B VITAMINS
Vitamin B1CAS 59-43-8Thiamine; AneurineVitamins (Vitamin B)Sunflower SeedsHelianthus annuusSeedHighEssential for converting dietary carbohydrates into cellular energy; supports normal nerve function and healthy heart muscle activity.
Vitamin B2CAS 83-88-5Riboflavin; Lactoflavin; E101Vitamins (Vitamin B)AlmondsPrunus dulcisNut KernelHighRequired for energy production from fats, proteins, and carbohydrates; supports healthy skin integrity and normal eye function.
Vitamin B3CAS 59-67-6Niacin; Nicotinic acid; NicotinamideVitamins (Vitamin B)PeanutsArachis hypogaeaSeedHighA precursor to NAD and NADP coenzymes central to energy metabolism; supports healthy DNA repair, normal skin function, and healthy circulation.
Vitamin B5CAS 79-83-4Pantothenic acid; PantothenateVitamins (Vitamin B)AvocadoPersea americanaFruitHighRequired for the synthesis of coenzyme A; supports the body's normal response to stress and healthy energy metabolism from all macronutrients.
Vitamin B6CAS 65-23-6Pyridoxine; Pyridoxal; PyridoxamineVitamins (Vitamin B)ChickpeasCicer arietinumSeedHighEssential for over 100 enzyme reactions including amino acid metabolism and neurotransmitter synthesis; supports normal mood regulation, cognitive function, and haemoglobin production.
Vitamin B7CAS 58-85-5Biotin; Vitamin HVitamins (Vitamin B)SoybeansGlycine maxSeedHighA coenzyme for carboxylase enzymes involved in fatty acid synthesis and gluconeogenesis; supports normal macronutrient metabolism, and healthy hair and nail growth.
Vitamin B9CAS 59-30-3Folate; Folic acid; Pteroylglutamic acidVitamins (Vitamin B)LentilsLens culinarisSeedHighEssential for one-carbon metabolism, normal DNA synthesis, and healthy cell division; critical during early pregnancy for normal foetal neural tube development.
Vitamin B12 (Corrinoid Analog)Pseudovitamin B12; Cobalamin analogVitamins (Vitamin B)NoriPorphyra spp.FrondsEmergingThe B12-like corrinoid compounds found in nori have contested bioactivity; current evidence suggests they may not function as true cobalamin and could potentially compete with active B12 for absorption. Not considered a reliable B12 source for those on plant-based diets.
ESTABLISHED VITAMIN-LIKE FACTORS
PQQCAS 72909-34-3Pyrroloquinoline quinone; Methoxatin; BioPQQVitamin-like FactorGreen PepperCapsicum annuumFruitModerateA redox-active cofactor studied for its potential to support mitochondrial biogenesis and contribute to mental clarity and focus when consumed as part of a healthy diet.
CholineCAS 62-49-7(2-Hydroxyethyl)trimethylammonium; BilineurineVitamin-like FactorWheat GermTriticum aestivumGermHighAn essential nutrient required for the synthesis of phosphatidylcholine and acetylcholine; critical for normal liver function, healthy brain development, and cognitive performance.
BetaineCAS 107-43-7Trimethylglycine; TMG; Glycine betaineVitamin-like FactorSugar BeetBeta vulgarisRootHighAn osmolyte and methyl donor that may support healthy liver function and contribute to normal homocysteine balance, a key cardiovascular health marker.
Quinic AcidCAS 77-95-21L-1(OH),3,4/5-Tetrahydroxycyclohexane-carboxylic acidVitamin-like FactorCranberryVaccinium macrocarponFruitModerateA plant acid that may support urinary tract health by contributing to hippuric acid production; also plays a role in the biosynthesis of aromatic amino acids in plants.
SolanesolCAS 13190-97-1All-trans-Solanesol; C45 isoprenyl alcoholVitamin-like FactorPotato LeavesSolanum tuberosumLeavesModerateA long-chain isoprenyl alcohol found in Solanaceae plants; studied as a biosynthetic precursor to coenzyme Q10 (CoQ10) and Vitamins E and K in certain organisms.
MACROMINERALS
CalciumCAS 7440-70-2Ca; Calcium ion; E170Minerals (Macromineral)Collard GreensBrassica oleraceaLeavesHighThe most abundant mineral in the human body; essential for structural bone and tooth health, normal muscle contraction, and healthy nerve signal transmission.
MagnesiumCAS 7439-95-4Mg; Magnesium ionMinerals (Macromineral)Pumpkin SeedsCucurbita pepoSeedHighA cofactor for over 300 enzymatic reactions; supports normal muscle and nerve function, healthy blood glucose regulation, and bone mineralisation.
PotassiumCAS 7440-09-7K; Potassium ionMinerals (Macromineral)BananaMusa acuminataFruitHighThe primary intracellular cation; essential for maintaining normal fluid balance, healthy blood pressure, and proper electrical activity in muscle and nerve cells.
PhosphorusCAS 7723-14-0P; Phosphate ionMinerals (Macromineral)OatsAvena sativaGrainsHighRequired by every cell for energy metabolism (ATP), DNA and RNA synthesis, and structural bone and tooth mineralisation in conjunction with calcium.
SulfurCAS 7704-34-9S; Organic sulfurMinerals (Macromineral)GarlicAllium sativumBulbHighAn essential component of the amino acids methionine and cysteine; required for the synthesis of glutathione, the body's primary endogenous antioxidant.
SodiumCAS 7440-23-5Na; Sodium ionMinerals (Macromineral)CeleryApium graveolensStalkHighThe primary extracellular cation; essential for maintaining normal fluid balance, blood pressure regulation, and healthy nerve and muscle electrical function.
ChlorideCAS 16887-00-6Cl-; Chloride ionMinerals (Macromineral)TomatoSolanum lycopersicumFruitHighThe primary extracellular anion; essential for maintaining acid-base balance and a component of hydrochloric acid required for normal gastric digestion.
TRACE MINERALS
IronCAS 7439-89-6Fe; Non-heme iron; Ferrous ironMinerals (Trace Mineral)SpinachSpinacia oleraceaLeavesHighA core component of haemoglobin and myoglobin; essential for normal oxygen transport throughout the body and healthy energy metabolism. Plant-source non-heme iron absorption is enhanced by Vitamin C.
ZincCAS 7440-66-6Zn; Zinc ionMinerals (Trace Mineral)Pumpkin SeedsCucurbita pepoSeedHighA cofactor for over 300 enzymes; supports normal immune function, healthy wound healing, DNA synthesis, and the senses of taste and smell.
CopperCAS 7440-50-8Cu; Cupric ionMinerals (Trace Mineral)CashewsAnacardium occidentaleNut KernelHighA cofactor for enzymes involved in iron metabolism, antioxidant defence (SOD), and connective tissue formation; supports healthy energy production and cardiovascular function.
ManganeseCAS 7439-96-5Mn; Manganese ionMinerals (Trace Mineral)HazelnutsCorylus avellanaNut KernelHighA cofactor for manganese superoxide dismutase and enzymes involved in bone formation; supports normal carbohydrate and fat metabolism.
SeleniumCAS 7782-49-2Se; Selenium ionMinerals (Trace Mineral)Brazil NutBertholletia excelsaNut KernelHighAn essential component of glutathione peroxidase and other selenoproteins; supports normal thyroid hormone metabolism and antioxidant protection of cells.
ChromiumCAS 7440-47-3Cr; Trivalent chromium; Cr3+Minerals (Trace Mineral)BroccoliBrassica oleraceaFloretsModerateMay enhance the action of insulin in supporting normal blood glucose uptake; studied for its role in healthy carbohydrate and lipid metabolism.
IodineCAS 7553-56-2I; Iodide ionMinerals (Trace Mineral)KelpMacrocystis pyriferaWhole PlantHighAn essential component of the thyroid hormones T3 and T4; required for normal metabolic rate, healthy growth, and neurological development.
MolybdenumCAS 7439-98-7Mo; Molybdenum ionMinerals (Trace Mineral)LentilsLens culinarisSeedHighA cofactor for several enzymes including xanthine oxidase and sulfite oxidase; essential for normal purine catabolism and sulfur amino acid metabolism.
SiliconCAS 7440-21-3Si; Soluble silica; Orthosilicic acidMinerals (Trace Mineral)HorsetailEquisetum arvenseStemsModerateStudied for its potential role in supporting collagen synthesis and normal bone and connective tissue formation; may contribute to healthy hair and nail strength.
BoronCAS 7440-42-8B; BorateMinerals (Trace Mineral)AvocadoPersea americanaFruitModerateStudied for its potential to support normal bone metabolism by influencing the utilisation of calcium, magnesium, and Vitamin D; may contribute to healthy hormonal balance.
VanadiumCAS 7440-62-2V; Vanadyl ion; VOSO4Minerals (Trace Mineral)DillAnethum graveolensLeavesEmergingA trace element studied in early-stage research for its potential to mimic insulin signalling and support healthy bone mineral density; human evidence remains limited.
NickelCAS 7440-02-0Ni; Nickel ionMinerals (Trace Mineral)BuckwheatFagopyrum esculentumSeedEmergingA trace element found in some urease and hydrogenase enzymes; studied for its minor role in gut microbiome metabolism. High dietary intake may cause sensitivity in some individuals.
LithiumCAS 7439-93-2Li; Lithium ionMinerals (Trace Mineral)CabbageBrassica oleraceaLeavesEmergingPresent in trace amounts in many plant foods; studied for its potential role in neuroprotection and emotional resilience at physiological dietary levels. Pharmacological doses are used clinically under medical supervision.
GermaniumCAS 7440-56-4Ge; Organic germaniumMinerals (Trace Mineral)GinsengPanax ginsengRootEmergingAn ultra-trace element found in some medicinal plants; studied in early-stage research for potential immunomodulatory properties. Evidence in humans is very limited.
StrontiumCAS 7440-24-6Sr; Strontium ionMinerals (Trace Mineral)Wheat BranTriticum aestivumOuter LayerModerateA trace element chemically similar to calcium; studied for its potential to support bone mineral density and skeletal tissue repair at physiological intake levels.
CobaltCAS 7440-48-4Co; Cobalt ionMinerals (Trace Mineral)PeasPisum sativumSeedHighAn essential component of Vitamin B12 (cobalamin); dietary cobalt supports the enzymatic functions of B12 in red blood cell formation and neurological health.
FluorideCAS 16984-48-8F-; Fluoride ionMinerals (Trace Mineral)Green TeaCamellia sinensisLeavesHighNaturally present in plant foods and drinking water; supports the remineralisation of tooth enamel and may help prevent dental caries at appropriate intake levels.
RubidiumCAS 7440-17-7Rb; Rubidium ionMinerals (Trace Mineral)Coffee BeanCoffea arabicaBeanEmergingAn ultra-trace element that may interact with potassium transport systems; studied in early-stage research for potential contributions to healthy cardiovascular electrical function.
CesiumCAS 7440-46-2Cs; Caesium ionMinerals (Trace Mineral)SpinachSpinacia oleraceaLeavesEmergingAn ultra-trace element present in very small quantities in plant foods; studied for its interaction with potassium channels at physiological trace levels. Not to be confused with pharmacological cesium applications.
MINERAL FACTORS
FerritinCAS 9007-73-2Plant Ferritin; PhytoferritinMineral Factor (Iron Storage Protein)SoybeanGlycine maxSeedModerateThe iron-storage protein found in plant seeds; studied as a potentially more stomach-friendly form of plant-derived iron with moderate bioavailability.
Inositol HexaphosphateCAS 83-86-3IP6; Phytic acid; InsP6; E391Mineral Factor (Phosphate Ester)Rice BranOryza sativaBranModerateA naturally occurring phosphorylated inositol studied for its potential antioxidant properties and ability to chelate iron in the gut; context-dependent effects on mineral absorption and cellular signalling.
AMINO ACIDS — PROTEINOGENIC
GlycineCAS 56-40-6Aminoacetic acid; GlycocollProteins (Amino Acid / Non-essential)SoybeanGlycine maxSeedModerateThe dominant residue of collagen and a substrate for glutathione and creatine synthesis; may support sleep quality and connective tissue repair.
L-ArginineCAS 74-79-3Arg; RProteins (Amino Acid / Conditionally essential)Pumpkin SeedsCucurbita pepoSeedModerateThe direct substrate for nitric oxide synthase; oral delivery is limited by intestinal and hepatic arginase first-pass metabolism.
L-CysteineCAS 52-90-4Cys; CProteins (Amino Acid / Conditionally essential)SoybeanGlycine maxSeedModerateThe rate-limiting substrate for glutathione synthesis; the free thiol oxidises readily to cystine on exposure to air.
L-GlutamineCAS 56-85-9Gln; Q; LevoglutamideProteins (Amino Acid / Conditionally essential)CabbageBrassica oleraceaLeavesModerateThe primary oxidative fuel of the intestinal mucosa; becomes conditionally essential during catabolic stress.
L-HistidineCAS 71-00-1His; HProteins (Amino Acid / Essential)BuckwheatFagopyrum esculentumSeedModerateThe precursor of carnosine and of histamine; essential in infancy and conditionally essential in adults.
L-LeucineCAS 61-90-5Leu; LProteins (Amino Acid / Essential, branched-chain)SoybeanGlycine maxSeedModerateThe branched-chain amino acid that triggers mTORC1 signalling for muscle protein synthesis; poorly water-soluble.
L-LysineCAS 56-87-1Lys; KProteins (Amino Acid / Essential)LentilsLens culinarisSeedHighThe first limiting amino acid in cereal protein and a required substrate for collagen crosslinking and carnitine synthesis.
L-TyrosineCAS 60-18-4Tyr; Y; 4-HydroxyphenylalanineProteins (Amino Acid / Conditionally essential)Pumpkin SeedsCucurbita pepoSeedModerateThe precursor of dopamine, noradrenaline and thyroid hormone; the least water-soluble proteinogenic amino acid.
AMINO ACIDS — NON-PROTEINOGENIC & DERIVATIVES
Beta-AlanineCAS 107-95-93-Aminopropanoic acidProteins (Amino Acid / Non-proteinogenic)AsparagusAsparagus officinalisSpearHighThe rate-limiting precursor of muscle carnosine; loading over four to ten weeks raises intramuscular buffering capacity.
L-CitrullineCAS 372-75-82-Amino-5-(carbamoylamino)pentanoic acidProteins (Amino Acid / Non-proteinogenic)WatermelonCitrullus lanatusFruit & RindHighBypasses intestinal arginase to raise plasma arginine more effectively per gram than arginine itself.
L-TheanineCAS 3081-61-6N-Ethyl-L-glutamineProteins (Amino Acid / Non-proteinogenic)Green TeaCamellia sinensisLeavesModerateStudied for its contribution to relaxed alertness, particularly in combination with caffeine.
TaurineCAS 107-35-72-Aminoethanesulfonic acidProteins (Amino Acid Derivative / Sulfonic)Red AlgaePalmaria palmataThallusModerateA conditionally essential sulfonic amino acid in bile acid conjugation, osmoregulation and cardiac function; largely absent from land plants.
Creatine MonohydrateCAS 6020-87-7Methylguanidinoacetic acid monohydrateProteins (Amino Acid Derivative / Guanidino)Vertebrate MuscleVariousSkeletal MuscleHighSupports phosphocreatine resynthesis for short-duration high-intensity work; the most extensively trialled ergogenic ingredient available.
N-Acetyl-L-CysteineCAS 616-91-1NAC; AcetylcysteineProteins (Amino Acid Derivative / Acetylated)Semi-synthetic from L-Cysteine—ModerateAn acetylated cysteine prodrug used to raise glutathione; the acetyl group protects the thiol through absorption.
N,N-Dimethylglycine HClCAS 2491-06-7DMG HCl; DimethylglycineProteins (Amino Acid Derivative / Methylated)BeansPhaseolus vulgarisSeedEmergingAn intermediate of choline and betaine catabolism; studied in early work for exercise and immune endpoints.
PEPTIDES
L-CarnosineCAS 305-84-0Beta-alanyl-L-histidineProteins (Dipeptide)Vertebrate MuscleVariousSkeletal MuscleModerateA histidine dipeptide acting as an intracellular pH buffer and carbonyl scavenger in skeletal muscle.
L-GlutathioneCAS 70-18-8GSH; gamma-Glu-Cys-GlyProteins (Tripeptide)AsparagusAsparagus officinalisSpearModerateThe principal endogenous intracellular antioxidant; oral bioavailability of the intact tripeptide remains debated.
PROTEINS — ANIMAL-DERIVED
CollagenCAS 9007-34-5Collagen peptides; Gelatin hydrolysateProteins (Structural / Fibrous)Bovine HideBos taurusHide & BoneModerateA glycine- and proline-rich structural protein; hydrolysed peptides such as Pro-Hyp appear in circulation and may act as signalling fragments.
ColostrumBovine colostrum; First milkProteins (Immune Complex)Bovine ColostrumBos taurusFirst-Milking ColostrumEmergingCarries immunoglobulins, lactoferrin and growth factors; studied for gut barrier and upper respiratory endpoints.
LactoferrinCAS 146897-68-9Lactotransferrin; LFProteins (Glycoprotein / Iron-binding)Bovine MilkBos taurusWheyModerateAn iron-binding glycoprotein with iron-sequestering antimicrobial activity; heat-labile, so processing conditions determine retention.
Egg IgYImmunoglobulin Y; Avian IgYProteins (Immunoglobulin)Hen Egg YolkGallus gallusYolkEmergingThe avian analogue of mammalian IgG; activity depends on whether the laying flock was specifically immunised.
Immunoglobulin YIgY; Egg yolk immunoglobulinProteins (Immunoglobulin)Hen Egg YolkGallus gallusYolkEmergingHeat- and acid-labile avian immunoglobulin; requires enteric protection for any intended intestinal activity.
Royal JellyApilak; 10-HDA sourceProteins (Glandular Secretion)Honeybee SecretionApis melliferaHypopharyngeal GlandEmergingA protein- and lipid-rich secretion standardised on 10-hydroxy-2-decenoic acid; a recognised allergen requiring declaration.
CARBOHYDRATES — POLYSACCHARIDES & OLIGOSACCHARIDES
Aloe PolysaccharidesAcemannan; Aloe mucilageCarbohydrates (Polysaccharide / Acetylated mannan)Aloe VeraAloe barbadensisLeaf Inner GelModerateAcetylated mannans standardised by degree of acetylation; aloin must be controlled separately as an anthraquinone limit.
LBP PolysaccharidesLycium barbarum polysaccharidesCarbohydrates (Polysaccharide / Arabinogalactan)Goji BerryLycium barbarumFruitEmergingArabinogalactan-protein complexes studied for immune and ocular endpoints; molecular weight distribution is not standardised across suppliers.
PolysaccharidesTotal polysaccharides; Crude polysaccharideCarbohydrates (Polysaccharide / Class entry)Various PlantsVariousVariousModerateA class assay rather than a compound; total-polysaccharide figures include alpha-glucans from substrate and are not interchangeable with beta-glucan content.
FOSFructooligosaccharides; OligofructoseCarbohydrates (Oligosaccharide / Prebiotic)ChicoryCichorium intybusRootHighShort-chain fructans fermented by colonic bifidobacteria; dose-dependent gastrointestinal tolerance limits inclusion.
Hyaluronic AcidCAS 9004-61-9Sodium hyaluronate; HyaluronanCarbohydrates (Glycosaminoglycan)Bacterial FermentationStreptococcus zooepidemicusCulture BrothModerateMolecular weight governs behaviour: high weight films on the surface, low weight penetrates; ingested polymer is depolymerised to fragments.
LIPIDS
EPA / DHA Omega-3CAS 10417-94-4 / 6217-54-5Eicosapentaenoic acid; Docosahexaenoic acidLipids (Fatty Acid / Long-chain omega-3)Marine AlgaeSchizochytrium spp.Whole CellHighThe long-chain omega-3 fatty acids; oxidation markers rather than assay are the governing quality specification.
Omega-6 Fatty AcidsLinoleic acid; GLA; Arachidonic acidLipids (Fatty Acid / Omega-6)Evening PrimroseOenothera biennisSeed OilModerateEssential fatty acids competing with omega-3 for desaturase enzymes; the ratio rather than absolute intake is the formulation variable.
PhytosterolsPlant sterols; Sterol estersLipids (Sterol / Class entry)Soybean OilGlycine maxSeed OilHighCompete with cholesterol for micellar incorporation; an authorised cholesterol-lowering claim exists at defined daily intakes.
PregnenoloneCAS 145-13-13-beta-Hydroxypregn-5-en-20-oneLipids (Steroid / Prohormone)Endogenous Steroid—EmergingThe committed precursor of all steroid hormones; not obtainable from wild yam, which supplies diosgenin that humans do not convert.
VITAMINS
BiotinCAS 58-85-5Vitamin B7; Vitamin HVitamins (Vitamin B)SoybeansGlycine maxSeedHighA carboxylase coenzyme; interferes with streptavidin-biotin immunoassays at supplemental doses, a documented clinical reporting hazard.
Folate / Folic AcidCAS 59-30-3Vitamin B9; Pteroylglutamic acidVitamins (Vitamin B)LentilsLens culinarisSeedHighRequired for one-carbon metabolism and DNA synthesis; folic acid is the synthetic vitamer and is more bioavailable than food folate.
NiacinCAS 59-67-6Vitamin B3; Nicotinic acid; NicotinamideVitamins (Vitamin B)PeanutsArachis hypogaeaSeedHighThe NAD and NADP precursor; nicotinic acid produces a prostaglandin-mediated flush that nicotinamide does not.
Pyridoxal 5'-PhosphateCAS 54-47-7P5P; PLP; Active B6Vitamins (Vitamin B / Active vitamer)ChickpeasCicer arietinumSeedHighThe active B6 cofactor for over a hundred enzymes; dephosphorylated in the intestine before absorption and rephosphorylated after.
Vitamin B ComplexB-complex; B vitaminsVitamins (Vitamin B / Class entry)Nutritional YeastSaccharomyces cerevisiaeWhole CellHighA class entry rather than a compound; vitamer and salt form decide the specification for each constituent.
Vitamin B12CAS 68-19-9Cobalamin; Cyanocobalamin; MethylcobalaminVitamins (Vitamin B)Bacterial FermentationPropionibacterium freudenreichiiCulture BrothHighRequired for methionine synthase and methylmalonyl-CoA mutase; absent from plants, so plant-based diets need a fortified or supplemental source.
Vitamin D3CAS 67-97-0CholecalciferolVitamins (Fat-soluble secosteroid)LichenCladonia rangiferinaThallusHighThe secosteroid hydroxylated to calcidiol then calcitriol; lichen-derived material is the vegan alternative to lanolin.
Vitamin ECAS 59-02-9Alpha-tocopherol; Tocopherols; TocotrienolsVitamins (Fat-soluble / Tocochromanol)Wheat GermTriticum aestivumGermHighA lipid-phase chain-breaking antioxidant protecting membrane polyunsaturated fatty acids from peroxidation.
Vitamin K2-MK7CAS 2124-57-4Menaquinone-7; MK-7Vitamins (Fat-soluble / Menaquinone)NattoBacillus subtilis nattoFermented SoybeanHighCarboxylates osteocalcin and matrix Gla protein; the long half-life of MK-7 distinguishes it from MK-4 and from K1.
BenfotiamineCAS 22457-89-2S-Benzoylthiamine O-monophosphateVitamins (Vitamin B / Synthetic derivative)Synthetic Thiamine Derivative—ModerateA lipid-soluble thiamine derivative that bypasses the saturable THTR transport limiting oral thiamine absorption.
VITAMIN-LIKE FACTORS & NUCLEOSIDES
Alpha-Lipoic AcidCAS 1077-28-7ALA; Thioctic acidVitamin-like Factor (Dithiol cofactor)SpinachSpinacia oleraceaLeavesModerateA mitochondrial dehydrogenase cofactor and amphipathic redox agent; the R-enantiomer is the biologically active form.
Coenzyme Q10CAS 303-98-0Ubiquinone; Ubidecarenone; CoQ10Vitamin-like Factor (Benzoquinone)SpinachSpinacia oleraceaLeavesModerateThe mitochondrial electron carrier between complexes I and III; poorly absorbed without a lipid vehicle.
MelatoninCAS 73-31-8N-Acetyl-5-methoxytryptamineVitamin-like Factor (Indoleamine)Tart CherryPrunus cerasusFruitHighThe pineal chronobiotic entraining circadian phase; regulated as a medicine in several markets.
AdenosineCAS 58-61-79-beta-D-RibofuranosyladenineNucleosides (Purine)CordycepsCordyceps militarisFruiting BodyEmergingA purine nucleoside and standardisation marker for Cordyceps; its receptor antagonism by caffeine underlies caffeine’s stimulant effect.
MINERALS & ORGANIC ACIDS
SilicaCAS 7631-86-9Silicon dioxide; Orthosilicic acid; E551Minerals (Trace Mineral)HorsetailEquisetum arvenseStemsModerateStudied for connective tissue and bone endpoints; bioavailability depends on conversion to soluble orthosilicic acid.
Malic AcidCAS 6915-15-7Hydroxybutanedioic acid; E296Organic Acids (Dicarboxylic / TCA intermediate)AppleMalus domesticaFruitModerateA tricarboxylic acid cycle intermediate used as an acidulant and as a salt counter-ion in citrulline and carnitine forms.
AMINO ACIDS — ESSENTIAL (CONTINUED)
L-IsoleucineCAS 73-32-5Ile; IProteins (Amino Acid / Essential, branched-chain)SoybeanGlycine maxSeedModerateBranched-chain amino acid with two chiral centres; both glucogenic and ketogenic, unlike leucine or valine.
L-ValineCAS 72-18-4Val; VProteins (Amino Acid / Essential, branched-chain)SoybeanGlycine maxSeedModeratePurely glucogenic branched-chain amino acid; the 2:1:1 BCAA ratio is convention rather than a dose-ranging result.
L-MethionineCAS 63-68-3Met; MProteins (Amino Acid / Essential, sulphur)Brazil NutBertholletia excelsaNut KernelHighThe principal methyl donor via S-adenosylmethionine; limiting amino acid in legume protein, and generates homocysteine on catabolism.
L-ThreonineCAS 72-19-5Thr; TProteins (Amino Acid / Essential)LentilsLens culinarisSeedHighExceptionally abundant in intestinal mucin; the gut extracts a large share on first pass.
L-PhenylalanineCAS 63-91-2Phe; FProteins (Amino Acid / Essential, aromatic)SoybeanGlycine maxSeedHighTyrosine and catecholamine precursor; carries a mandatory phenylketonuria declaration in most markets.
L-TryptophanCAS 73-22-3Trp; WProteins (Amino Acid / Essential, aromatic)Pumpkin SeedsCucurbita pepoSeedHighAround 95% of catabolism runs to NAD⁺ via kynurenine; roughly 60 mg equates to 1 mg niacin equivalent.
DL-TryptophanCAS 54-12-6Racemic tryptophanProteins (Amino Acid / Racemate)Chemical Synthesis—ModerateThe D-isomer converts only partially, and food use of the racemate is restricted in many markets.
DL-MethionineCAS 59-51-8Racemic methionineProteins (Amino Acid / Racemate)Chemical Synthesis—HighUnusually, the D-isomer converts efficiently in liver and kidney, so the racemate carries real nutritional value.
AMINO ACIDS — NON-ESSENTIAL & NON-PROTEINOGENIC (CONTINUED)
L-SerineCAS 56-45-1Ser; SProteins (Amino Acid / Non-essential)SoybeanGlycine maxSeedHighThe principal one-carbon donor to tetrahydrofolate and the committed precursor of the entire sphingolipid class.
L-ProlineCAS 147-85-3Pro; PProteins (Imino Acid / Non-essential)Wheat GlutenTriticum aestivumEndospermHighThe ring-constrained backbone that makes the collagen triple helix geometrically possible; markedly hygroscopic.
L-AlanineCAS 56-41-7Ala; AProteins (Amino Acid / Non-essential)SoybeanGlycine maxSeedHighPrincipal nitrogen carrier of the glucose-alanine cycle; distinct from beta-alanine, with no carnosine role.
DL-AlanineCAS 302-72-7Racemic alanineProteins (Amino Acid / Racemate)Chemical Synthesis—HighA sweet-tasting taste modifier rather than a nutrient; sweetness perception is not stereospecific.
L-Aspartic AcidCAS 56-84-8Asp; DProteins (Amino Acid / Non-essential, acidic)AsparagusAsparagus officinalisSpearHighDonates the second urea nitrogen and carries reducing equivalents in the malate-aspartate shuttle; aspartame feedstock.
D-Aspartic AcidCAS 1783-96-6DAA; D-AspProteins (Amino Acid / D-enantiomer)Endogenous Neuroendocrine Tissue—EmergingA genuine endogenous signalling molecule; the testosterone claim failed replication, with one trial finding a decrease at 6 g.
L-Glutamic AcidCAS 56-86-0Glu; E; GlutamateProteins (Amino Acid / Non-essential, acidic)KombuSaccharina japonicaThallusHighThe central node of amino acid nitrogen metabolism and the umami taste compound; distinct from monosodium glutamate.
L-Asparagine MonohydrateCAS 5794-13-2Asn; NProteins (Amino Acid / Non-essential, amide)AsparagusAsparagus officinalisSpearHighThe limiting precursor of acrylamide in heated foods; the N-linked glycosylation attachment point.
L-HydroxyprolineCAS 51-35-4Hyp; trans-4-Hydroxy-L-prolineProteins (Imino Acid / Non-proteinogenic)Gelatin HydrolysateBos taurusHide & BoneHighMade post-translationally on proline already in the collagen chain, so free hydroxyproline cannot be incorporated.
L-OrnithineCAS 70-26-8OrnProteins (Amino Acid / Non-proteinogenic)Endogenous Urea Cycle—ModerateThe urea cycle carrier, regenerated rather than consumed; committed precursor of the polyamines.
L-NorvalineCAS 6600-40-42-Aminopentanoic acidProteins (Amino Acid / Non-proteinogenic)Chemical Synthesis—EmergingInhibits arginase in vitro; no human efficacy evidence and an unresolved cell-toxicity signal.
L-Pyroglutamic AcidCAS 98-79-8PCA; 5-Oxo-L-prolineProteins (Amino Acid Derivative / Lactam)Human Stratum Corneum—HighA major constituent of the skin natural moisturising factor; the standard degradation marker for glutamine and glutamate.
N-Acetyl-L-TyrosineCAS 537-55-3NALTProteins (Amino Acid Derivative / Acetylated)Acetylation of L-Tyrosine—HighFar more soluble than tyrosine but poorly deacetylated, so it raises plasma tyrosine less per gram.
L-DOPACAS 59-92-0Levodopa; 3,4-Dihydroxy-L-phenylalanineProteins (Amino Acid / Non-proteinogenic)Velvet BeanMucuna pruriensSeedHighThe immediate dopamine precursor crossing the blood-brain barrier; a registered medicine in most markets.
AMINO ACID SALT FORMS
L-Arginine HClCAS 1119-34-2Arginine hydrochlorideProteins (Amino Acid Salt / Hydrochloride)Acidified L-Arginine—High82.7% free base; drops solution pH from above 10.5 into the workable 5 to 6.5 range for liquids.
L-Arginine L-AspartateCAS 7675-83-4Arginine aspartateProteins (Amino Acid Salt / Aspartate)Combined Amino Acid Ions—High56.7% arginine; chloride-free and near-neutral in solution, with both ions in the urea cycle.
L-Arginine Alpha-KetoglutarateCAS 16856-18-1AAKGProteins (Amino Acid Salt / Ketoglutarate)Combined Ions—High70.5% arginine at the 2:1 ratio; controlled performance trials returned null results.
L-Lysine HClCAS 657-27-2Lysine hydrochlorideProteins (Amino Acid Salt / Hydrochloride)Acidified L-Lysine—HighExactly 80% free base; feed declares lysine on a free-base basis while supplement labelling does not agree.
L-Lysine AcetateCAS 57282-49-2Lysine acetateProteins (Amino Acid Salt / Acetate)Neutralised L-Lysine—High70.9% free base; acetate is metabolised to bicarbonate, making it base- rather than acid-generating.
L-Cysteine HCl MonohydrateCAS 7048-04-6Cysteine hydrochloride monohydrateProteins (Amino Acid Salt / Hydrochloride)Acidified L-Cysteine—High69.0% free base; the low solution pH suppresses thiol oxidation to cystine. Food additive E920.
L-Ornithine HClCAS 3184-13-2Ornithine hydrochlorideProteins (Amino Acid Salt / Hydrochloride)Acidified L-Ornithine—High78.4% free base; the free base deliquesces, and the chloride fraction is the highest of the series.
L-Ornithine L-AspartateCAS 3230-94-2LOLAProteins (Amino Acid Salt / Aspartate)Combined Amino Acid Ions—Moderate49.8% ornithine; a dual hepatic and muscle ammonia route, and a registered medicine in several markets.
L-Citrulline DL-MalateCAS 54940-97-5Citrulline malateProteins (Amino Acid Salt / Malate)Combined Ions—ModerateThe undeclared 2:1 or 1:1 ratio swings citrulline content from 72.3% to 56.6%.
Magnesium AspartateCAS 2068-80-6Mg aspartateMinerals (Organic Magnesium Salt)Reaction with L-Aspartic Acid—HighOnly 7.5 to 8.4% elemental magnesium, the lowest of the common salts; 300 mg of magnesium needs 3.6 g of salt.
CARNITINE & CREATINE FORMS
L-CarnitineCAS 541-15-1LevocarnitineProteins (Quaternary Amine / Conditionally essential)Vertebrate MuscleVariousSkeletal MuscleHighMitochondrial long-chain fatty acid carrier; the free base deliquesces and D-carnitine inhibits its transport.
L-Carnitine L-TartrateCAS 36687-82-8LCLTProteins (Carnitine Salt / Tartrate)Combined with L-Tartaric Acid—High68.2% carnitine and non-hygroscopic — the reason dry carnitine formats are possible at all.
L-Carnitine FumarateCAS 90471-79-7Carnitine fumarateProteins (Carnitine Salt / Fumarate)Combined with Fumaric Acid—High58.1% carnitine with an achiral, non-wine-derived counter-ion that is itself a TCA intermediate.
N-Acetyl-L-Carnitine HClCAS 5080-50-2ALCAR HClProteins (Carnitine Derivative / Acetyl ester)Acetylation of L-Carnitine—ModerateCrosses the blood-brain barrier where carnitine does not, and donates acetyl groups to the acetyl-CoA pool.
Creatine HClCAS 17050-09-8Creatine hydrochlorideProteins (Creatine Salt / Hydrochloride)Acidified Synthetic Creatine—High78.2% creatine against monohydrate 87.9%; the solubility advantage is real, the lower-dose claim is not.
VITAMINS & VITAMERS (CONTINUED)
ThiamineCAS 67-03-8Vitamin B1; Thiamine HClVitamins (Vitamin B)Sunflower SeedsHelianthus annuusSeedHighLeast heat-stable B vitamin, worsening as pH rises, and destroyed outright by sulphites.
RiboflavinCAS 83-88-5Vitamin B2; E101Vitamins (Vitamin B)AlmondsPrunus dulcisNut KernelHighStrongly photolabile, and its degradation product lumiflavin oxidises any vitamin C present.
PyridoxineCAS 58-56-0Vitamin B6; Pyridoxine HClVitamins (Vitamin B)ChickpeasCicer arietinumSeedHighThe only water-soluble vitamin with a neurotoxicity-based upper limit; EFSA revised it to 12 mg/day in 2023.
Pantothenic AcidCAS 79-83-4Vitamin B5; Calcium pantothenateVitamins (Vitamin B)AvocadoPersea americanaFruitHighThe free acid is a hygroscopic oil, so calcium D-pantothenate is the article; only the D-form is active.
Vitamin ACAS 68-26-8Retinol; Retinyl palmitateVitamins (Fat-soluble Retinoid)CarrotDaucus carotaRootHighPreformed retinol is teratogenic at high intake; provitamin A carotenoids are not, their conversion being regulated.
Nicotinamide MononucleotideCAS 1094-61-7NMN; beta-NMNNucleotides (Pyridine / NAD⁺ precursor)Enzymatic Synthesis—EmergingA direct NAD⁺ precursor; treated by the FDA as excluded from the supplement definition and not an EU novel food.
LIPIDS & STRUCTURAL MATERIALS (CONTINUED)
DHACAS 6217-54-5Docosahexaenoic acid; 22:6 n-3Lipids (Fatty Acid / Long-chain omega-3)Marine AlgaeSchizochytrium spp.Whole CellHighDominant fatty acid of retinal photoreceptor membranes; six double bonds make oxidation specification mandatory.
Soy PhosphatidylcholineCAS 8002-43-5Soy lecithin PCLipids (Phospholipid)SoybeanGlycine maxSeed OilModerateThe principal liposome-forming phospholipid; phosphatidylcholine content rather than lecithin weight is the specification.
PolicosanolLong-chain aliphatic alcoholsLipids (Fatty Alcohol Mixture)Sugar CaneSaccharum officinarumWaxEmergingCuban trials reported lipid effects that independent replication outside Cuba has not confirmed.
Saw Palmetto Fatty AcidsSerenoa lipidosterolic extractLipids (Free Fatty Acid Complex)Saw PalmettoSerenoa repensFruitModerateStandardised on total free fatty acids; the hexane and CO₂ extracts differ materially in composition.
Avocado-Soybean UnsaponifiablesASULipids (Unsaponifiable Sterol Fraction)Avocado & SoybeanPersea americanaFruit & Seed OilModerateA one-third avocado to two-thirds soybean unsaponifiable fraction studied for joint comfort endpoints.
Eggshell Membrane CollagenESM; Natural eggshell membraneProteins (Structural Matrix)Hen Eggshell MembraneGallus gallusMembraneModerateA native collagen and glycosaminoglycan matrix rather than a hydrolysate; joint trials used 500 mg of whole membrane.
PhycocyaninCAS 11016-15-2C-Phycocyanin; Spirulina blueProteins (Phycobiliprotein)SpirulinaArthrospira platensisWhole CellModerateA blue phycobiliprotein used as both colourant and antioxidant active; heat- and light-labile.
Fulvic AcidCAS 479-66-3Shilajit fulvic fractionOrganic Acids (Humic Substance)ShilajitHumic ExudateRock ExudateEmergingA heterogeneous humic fraction rather than a defined compound; heavy metal specification is the governing control.
Hydroxycitric AcidCAS 6205-14-7HCA; Garcinia HCAOrganic Acids (Tricarboxylic)Malabar TamarindGarcinia cambogiaFruit RindEmergingAn ATP-citrate lyase inhibitor in vitro; human weight outcomes are small and inconsistent.
AcemannanCAS 110042-95-0Aloe acetylated mannanCarbohydrates (Polysaccharide / Acetylated mannan)Aloe VeraAloe barbadensisLeaf Inner GelModerateStandardised by degree of acetylation; aloin must be limited separately as an anthraquinone control.

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// SECONDARY METABOLITES: BIOACTIVE SIGNALS
Compound Also Known As Class (Sub-class) Botanical Source Plant Part Claim Strength Primary Biological Action
ISOQUINOLINE ALKALOIDS
MorphineCAS 57-27-2Morphia; MS Contin; OpioidAlkaloid (Isoquinoline)Opium PoppyPapaver somniferumUnripe Capsule LatexHighA clinically established opioid analgesic used under medical supervision for severe pain management; associated with significant dependence and respiratory depression risk.
CodeineCAS 76-57-33-Methylmorphine; Codeine phosphateAlkaloid (Isoquinoline)Opium PoppyPapaver somniferumUnripe Capsule LatexHighA mild opioid used clinically for moderate pain relief and cough suppression; subject to controlled substance regulations in most jurisdictions.
BerberineCAS 2086-83-15,6-Dihydro-9,10-dimethoxybenzo[g]-1,3-benzodioxolo[5,6-a]quinoliziniumAlkaloid (Isoquinoline)Goldenseal / BarberryHydrastis canadensis / Berberis spp.Roots and RhizomesHighWell-studied for supporting healthy blood glucose and lipid metabolism; may help maintain normal gut microbial balance. Multiple human trials available.
GalantamineCAS 357-70-0Galanthamine; Reminyl; NivalinAlkaloid (Isoquinoline)Snowdrop / DaffodilGalanthus spp.BulbsHighA clinically approved acetylcholinesterase inhibitor used medically to support cognitive function in Alzheimer's disease.
PapaverineCAS 58-74-21-[(3,4-Dimethoxyphenyl)methyl]-6,7-dimethoxyisoquinolineAlkaloid (Isoquinoline)Opium PoppyPapaver somniferumCapsule LatexHighA clinically used smooth muscle relaxant that dilates blood vessels; used medically for vascular spasm under supervision.
NoscapineCAS 128-62-1Narcotine; l-NoscapineAlkaloid (Isoquinoline)Opium PoppyPapaver somniferumCapsule LatexHighA non-addictive antitussive alkaloid used clinically to suppress dry cough without significant CNS depression.
EmetineCAS 483-18-12-Ethyl-3-(3,4-dimethoxybenzyl)-9,10-dimethoxy-1,2,3,4-tetrahydroisoquinolineAlkaloid (Isoquinoline)IpecacCephaelis ipecacuanhaRoots and RhizomesModerateHistorically used as an amoebicidal agent; at low doses acts as an expectorant. High doses are emetic. Subject to strict dosing due to cardiotoxicity risk.
SanguinarineCAS 2447-54-3Pseudochelerythrine; 13-Methylbenzo[g]benzofuro[3,2-b]quinoliniumAlkaloid (Isoquinoline)BloodrootSanguinaria canadensisRhizomeModerateStudied for antimicrobial and antiplaque properties at low concentrations; notable cytotoxicity limits internal use.
TetrahydropalmatineCAS 10097-84-4L-THP; Corydalis alkaloid; dl-TetrahydropalmatineAlkaloid (Isoquinoline)CorydalisCorydalis yanhusuoRhizomeModerateStudied for analgesic and mild sedative properties; may support sleep quality and pain management. Used in traditional Chinese medicine.
HydrastineCAS 118-08-1beta-Hydrastine; Isoquinoline alkaloidAlkaloid (Isoquinoline)GoldensealHydrastis canadensisRhizomeModerateStudied for its astringent and haemostatic properties; may support mucosal tissue health at appropriate doses.
CanadineCAS 522-97-4L-Tetrahydroberberine; (R,S)-CanadineAlkaloid (Isoquinoline)GoldensealHydrastis canadensisRhizomeModerateStudied for sedative and analgesic properties; may offer neuroprotective support in early-stage research.
CoptisineCAS 6020-18-45,6-Dihydro-9,10-dimethoxy-1,3-dioxolo[4,5-g]isoquinoliniumAlkaloid (Isoquinoline)GoldthreadCoptis chinensisRhizomeModerateStudied for antimicrobial and antiviral properties in laboratory settings; supports the traditional use of goldthread in digestive health.
PalmatineCAS 3486-67-7Palmatine chloride; FibrauretinAlkaloid (Isoquinoline)Amur Cork TreePhellodendron amurenseBarkModerateStudied for antimicrobial and blood glucose-supporting properties; closely related structurally to berberine.
JatrorrhizineCAS 3621-38-3Jateorhizine; VillanovineAlkaloid (Isoquinoline)BarberryBerberis vulgarisRoot BarkModerateStudied for antifungal and hepatoprotective properties in preclinical models; part of the berberine-type alkaloid family.
CorydalineCAS 518-69-4d-Corydaline; Isoquinoline alkaloidAlkaloid (Isoquinoline)CorydalisCorydalis yanhusuoRhizome / TuberModerateStudied for analgesic properties in animal models; may contribute to the pain-management activity of Corydalis preparations.
ChelidonineCAS 476-32-4Chelidonium alkaloid; Major alkaloid of CelandineAlkaloid (Isoquinoline)Greater CelandineChelidonium majusRoots / SapModerateStudied for antispasmodic and choleretic effects; may support bile flow and digestive tract muscle relaxation at appropriate doses.
ProtopineCAS 130-86-9Fumarine; MacleyineAlkaloid (Isoquinoline)FumitoryFumaria officinalisAerial PartsModerateStudied for antispasmodic effects on smooth muscle; may contribute to the digestive-soothing properties of fumitory preparations.
CephaelineCAS 483-17-0Ipecac alkaloid; 2'-DesmethylemetineAlkaloid (Isoquinoline)IpecacCephaelis ipecacuanhaRootsModerateA potent emetic agent and amoebicide; contributes to the medicinal activity of ipecac alongside emetine.
LaudanosineCAS 2688-77-9Laudanum alkaloid; N-MethyltetrahydropapaverineAlkaloid (Isoquinoline)Opium PoppyPapaver somniferumCapsule LatexEmergingA minor opiate alkaloid studied in toxicological research; at high doses associated with CNS excitation. Not used therapeutically.
LaudanineCAS 301-21-3Isoquinoline alkaloid; Laudanum constituentAlkaloid (Isoquinoline)Opium PoppyPapaver somniferumCapsule LatexEmergingA minor alkaloid studied in pharmacognosy; closely related to laudanosine with mild dopaminergic interactions.
NeopineCAS 467-14-1Beta-Codeine; 6-Deoxy-codeineAlkaloid (Isoquinoline)Opium PoppyPapaver somniferumCapsule LatexEmergingA codeine isomer studied as a mild antitussive with low dependence potential; primarily of pharmacognostic interest.
ThebaineCAS 115-37-7Paramorphine; Codeine methyl enol etherAlkaloid (Isoquinoline)Opium PoppyPapaver somniferumCapsule LatexHighA toxic stimulant opiate alkaloid used industrially as a pharmaceutical precursor for opioid analgesics and antagonists including naloxone.
PseudomorphineCAS 125-24-6Dehydromorphine dimerAlkaloid (Isoquinoline)Opium PoppyPapaver somniferumCapsule LatexEmergingAn oxidative dimer of morphine with no significant opioid receptor activity; of interest primarily in forensic and analytical chemistry.
ReticulineCAS 18797-79-0(R,S)-Norcoclaurine-derived; MIA precursorAlkaloid (Isoquinoline)Opium PoppyPapaver somniferumCapsule LatexEmergingThe central biosynthetic precursor from which the plant derives most of its complex benzylisoquinoline alkaloids; studied extensively in metabolic engineering.
PorphyroxineCAS 4017-67-2Isoquinoline alkaloid; Opium minorAlkaloid (Isoquinoline)Opium PoppyPapaver somniferumCapsule LatexEmergingA minor reactive opiate constituent; primarily referenced in forensic chemistry for identification of opium-derived preparations.
CryptopineCAS 482-74-6Isoquinoline alkaloidAlkaloid (Isoquinoline)Opium PoppyPapaver somniferumCapsule LatexEmergingA minor opium alkaloid that may contribute mild sedative and cardiac slowing effects at high doses; primarily of research interest.
NarceineCAS 131-28-2Narcosine; Narceine hydrateAlkaloid (Isoquinoline)Opium PoppyPapaver somniferumCapsule LatexModerateA non-addictive opium alkaloid with mild antitussive properties; studied for its calming effect on the respiratory mucosa.
ColumbamineCAS 3621-36-1Columbamine chloride; Yellow dye alkaloidAlkaloid (Isoquinoline)GoldensealHydrastis canadensisRhizomeModerateStudied for its potential to support intestinal mucosal barrier integrity and modulate gut inflammatory responses.
WorenineCAS 6873-09-2Coptis alkaloid; Yellow pigmentAlkaloid (Isoquinoline)GoldthreadCoptis chinensisRhizomeModerateStudied for broad-spectrum antimicrobial activity including against drug-resistant gut pathogens.
EpiberberineCAS 6873-15-013-Epi-berberineAlkaloid (Isoquinoline)GoldthreadCoptis chinensisRhizomeModerateStudied for effects on hepatic lipid metabolism; may help regulate fat accumulation in liver tissue.
GroenlandicineCAS 6873-13-8Coptis alkaloid; Isoquinoline pigmentAlkaloid (Isoquinoline)GoldthreadCoptis chinensisRhizomeEmergingStudied for neuroprotective potential; preliminary research suggests it may help protect nerve cells from oxidative stress-induced damage.
BulbocapnineCAS 298-45-3(+)-Bulbocapnine; Aporphine alkaloidAlkaloid (Isoquinoline)CorydalisCorydalis cavaTuberModerateStudies for effects on motor function and vestibular disturbances; historically researched for its dopamine-receptor interactions.
OripavineCAS 467-04-914-Hydroxycodeinone precursor; Opium alkaloidAlkaloid (Isoquinoline)Opium PoppyPapaver somniferumCapsule LatexModerateA highly potent opiate alkaloid used as a pharmaceutical precursor to produce buprenorphine and other advanced opioid medications.
StrictosidineCAS 22255-40-9Isovincoside; Universal MIA precursorAlkaloid (Indole)Madagascar PeriwinkleCatharanthus roseusLeavesEmergingThe universal biosynthetic precursor from which the plant assembles all of its complex monoterpenoid indole alkaloids; of central interest in metabolic engineering research.
PsychotrineCAS 20001-63-4Ipecac minor alkaloidAlkaloid (Isoquinoline)IpecacCephaelis ipecacuanhaRootsEmergingA minor ipecac constituent that may contribute to the plant's amoebicidal activity alongside emetine and cephaeline.
INDOLE ALKALOIDS
VincristineCAS 57-22-7Leurocristine; VCR; OncovinAlkaloid (Indole)Madagascar PeriwinkleCatharanthus roseusAerial PartsHighA clinically approved vinca alkaloid used medically in cancer chemotherapy, particularly for leukaemia; administered under medical supervision only.
VinblastineCAS 865-21-4Vincaleukoblastine; VLB; VelbanAlkaloid (Indole)Madagascar PeriwinkleCatharanthus roseusAerial PartsHighA clinically approved vinca alkaloid used medically in cancer chemotherapy; inhibits microtubule formation during cell division.
ReserpineCAS 50-55-5Serpasil; RaudixinAlkaloid (Indole)Indian SnakerootRauvolfia serpentinaDried RootsHighA clinically established antihypertensive and antipsychotic that depletes catecholamine stores; now largely superseded by newer drugs due to side effect profile.
AjmalineCAS 4360-12-7Cardiorythmine; GilurytmalAlkaloid (Indole)Indian SnakerootRauvolfia serpentinaDried RootsHighA clinically used class Ia antiarrhythmic; administered under medical supervision for ventricular arrhythmias.
Huperzine ACAS 102518-79-6HupA; Selagine; Huperzia alkaloidAlkaloid (Lycopodium)Toothed ClubmossHuperzia serrataWhole PlantModerateStudied for acetylcholinesterase inhibition and potential support for cognitive function and memory; multiple small human trials available with promising but preliminary results.
PhysostigmineCAS 57-47-6Eserine; CalabarineAlkaloid (Indole)Ordeal BeanPhysostigma venenosumSeedsHighA clinically used reversible acetylcholinesterase inhibitor; administered medically for glaucoma and as an antidote for anticholinergic poisoning.
ErgotamineCAS 113-15-5Ergomar; Cafergot constituentAlkaloid (Indole)Ergot FungusClaviceps purpureaSclerotiumHighA clinically established vasoconstrictor used medically for acute migraine management; associated with ergotism risk at high doses.
VincamineCAS 1617-90-9Vincamone; OxicebralAlkaloid (Indole)Lesser PeriwinkleVinca minorLeavesModerateStudied for its potential to improve cerebral blood flow; may support cognitive function in age-related decline, with limited clinical trial data.
IbogaineCAS 83-74-9Ibogaine HCl; Tabernanthe alkaloidAlkaloid (Indole)IbogaTabernanthe ibogaRoot BarkEmergingStudied for potential to interrupt addiction pathways, particularly for opioid and alcohol dependence; associated with serious cardiac risks and altered sensory perception. Controlled substance in most jurisdictions.
HarmineCAS 442-51-3Telepathine; Leucoharmine; Syrian Rue alkaloidAlkaloid (Indole)Syrian RuePeganum harmalaSeedsModerateA reversible monoamine oxidase inhibitor (MAOI); studied for effects on neuroplasticity, mood, and potential neuroprotective activity. Psychoactive at higher doses.
HarmalineCAS 304-21-23,4-Dihydroharmine; beta-carbolineAlkaloid (Beta-carboline)Syrian RuePeganum harmalaSeedsModerateA short-acting reversible MAOI studied for potential neurological effects; alters neurotransmitter metabolism. Psychoactive at higher doses.
TetrahydroharmineCAS 7629-35-8THH; LeptaflorineAlkaloid (Beta-carboline)Ayahuasca VineBanisteriopsis caapiStem / BarkEmergingStudied for weak serotonin reuptake inhibitory activity; contributes to the pharmacological profile of ayahuasca preparations alongside MAOIs.
HarmalolCAS 304-20-13,4-Dihydro-1-methyl-beta-carbolineAlkaloid (Beta-carboline)Syrian RuePeganum harmalaSeedsEmergingA minor beta-carboline studied for antioxidant and potential neuroprotective properties in early-stage laboratory research.
HarmolCAS 487-03-61-Methyl-beta-carboline; Harmine metaboliteAlkaloid (Beta-carboline)Syrian RuePeganum harmalaSeedsEmergingA beta-carboline studied for muscle relaxant properties in animal models; minor constituent of Syrian rue with mild CNS activity.
CatharanthineCAS 2468-21-5Iboga-type alkaloid; Vinca precursorAlkaloid (Indole)Madagascar PeriwinkleCatharanthus roseusLeavesModerateA biosynthetic precursor alkaloid that combines with vindoline to form dimeric vinca alkaloids; studied in metabolic engineering for anticancer compound production.
VindolineCAS 2182-14-1Vinca alkaloid monomerAlkaloid (Indole)Madagascar PeriwinkleCatharanthus roseusLeavesModerateA monomeric precursor that combines biosynthetically with catharanthine to produce the clinically important vincristine and vinblastine.
RescinnamineCAS 24815-24-5Moderil; Rauvolfia alkaloidAlkaloid (Indole)Indian SnakerootRauvolfia serpentinaRootsModerateA Rauvolfia alkaloid with antihypertensive properties; studied for its ability to reduce blood pressure by depleting peripheral noradrenaline stores.
DeserpidineCAS 131-01-1Canescine; HarmonylAlkaloid (Indole)Indian SnakerootRauvolfia serpentinaRootsModerateAn antihypertensive and tranquilising Rauvolfia alkaloid related to reserpine; historically used clinically for hypertension management.
SerpentineCAS 18786-24-8Rauvolfia alkaloid; CNS depressantAlkaloid (Indole)Indian SnakerootRauvolfia serpentinaDried RootsModerateA companion alkaloid to reserpine in Rauvolfia; studied for its CNS depressant and hypotensive properties.
RauwolscineCAS 131-03-3Alpha-Yohimbine; IsoyohimbineAlkaloid (Indole)Indian SnakerootRauvolfia serpentinaRootsModerateStudied as an alpha-2 adrenergic receptor antagonist; may support fat mobilisation and mildly elevate sympathetic nervous tone.
SarpagineCAS 6752-54-1Rauvolfia alkaloid; Indole precursorAlkaloid (Indole)Indian SnakerootRauvolfia serpentinaRootsEmergingA foundational indole alkaloid in Rauvolfia; studied as a biosynthetic scaffold for the plant's antihypertensive alkaloid family.
VellosimineCAS 6886-97-1Rauvolfia minor alkaloidAlkaloid (Indole)Indian SnakerootRauvolfia serpentinaRootsEmergingA minor sedative alkaloid in the Rauvolfia complex; contributes to the plant's overall CNS-modulatory activity.
AricineCAS 482-63-3Rauvolfia alkaloidAlkaloid (Indole)Indian SnakerootRauvolfia serpentinaRootsEmergingStudied for its contribution to the antihypertensive effect of Rauvolfia by supporting depletion of norepinephrine reserves.
AjmalicidineCAS 6877-33-4Rauvolfia minor alkaloidAlkaloid (Indole)Indian SnakerootRauvolfia serpentinaRootsEmergingStudied in early-stage research for potential effects on cerebral blood flow and age-related cognitive support.
SeredamineRauvolfia serotonin modulatorAlkaloid (Indole)Indian SnakerootRauvolfia serpentinaRootsEmergingStudied for serotonin receptor interactions; contributes to the complex neurological pharmacology of Rauvolfia root preparations.
PelirineRauvolfia minor alkaloidAlkaloid (Indole)Indian SnakerootRauvolfia serpentinaRootsEmergingA minor alkaloid supporting the overall antihypertensive and sedative profile of the Rauvolfia alkaloid complex.
GramineCAS 87-52-53-(Dimethylaminomethyl)indole; DonaxineAlkaloid (Indole)Giant ReedArundo donaxLeavesEmergingA tryptamine-derived indole alkaloid studied for smooth muscle effects; associated with vasoconstriction in animal studies.
BrucineCAS 357-57-32,3-Dimethoxystrychnidin-10-oneAlkaloid (Indole)Strychnine TreeStrychnos nux-vomicaSeedsEmergingA highly toxic glycine receptor antagonist related to strychnine; studied in toxicology. Not therapeutically used. Severe CNS toxicity at very low doses.
VomicineCAS 125-15-5Strychnidin-10-one derivativeAlkaloid (Indole)Strychnine TreeStrychnos nux-vomicaSeedsEmergingA highly toxic Strychnos alkaloid associated with severe CNS excitation and convulsions; documented for toxicological reference only.
StrychnineCAS 57-24-9Strychnidin-10-one; Nux vomica alkaloidAlkaloid (Indole)Strychnine TreeStrychnos nux-vomicaDried SeedsEmergingA potent glycine antagonist causing CNS hyperexcitability; historically used in sub-toxic doses as a tonic. Associated with severe toxicity — documented for reference only.
MitragynineCAS 4098-40-2Mitrajavine; Kratom major alkaloidAlkaloid (Indole)KratomMitragyna speciosaLeavesModerateThe primary alkaloid of kratom; studied for partial opioid receptor agonism and potential analgesic activity. Subject to ongoing regulatory review and dependence concerns.
7-HydroxymitragynineCAS 174418-82-77-OH-Mitragynine; Kratom minor alkaloidAlkaloid (Indole)KratomMitragyna speciosaLeavesModerateA potent minor kratom alkaloid with higher opioid receptor affinity than mitragynine; studied for analgesic effects but associated with dependence risk.
SpeciociliatineCAS 4098-41-3Kratom minor alkaloidAlkaloid (Indole)KratomMitragyna speciosaLeavesEmergingA minor kratom alkaloid studied for distinct receptor binding; may contribute muscle-relaxant and analgesic components to the overall kratom pharmacological profile.
CorynoxineKratom / Cat's Claw alkaloidAlkaloid (Indole)Kratom / Cat's ClawMitragyna speciosaLeaves / BarkEmergingStudied in early-stage research for potential neuroprotective activity related to autophagy induction and protein clearance in neural tissue.
RhynchophyllineCAS 76-66-4Uncaria tetracyclic alkaloidAlkaloid (Indole)Cat's ClawUncaria tomentosaInner BarkModerateStudied for calcium channel blocking activity and potential cardiovascular and neuroprotective effects; may support healthy blood pressure.
IsorhynchophyllineUncaria alkaloid; Tetracyclic oxindoleAlkaloid (Indole)Cat's ClawUncaria tomentosaInner BarkEmergingStudied for neuroprotective properties in hypoxic conditions; early-stage research suggests potential support for neuronal survival.
YohimbineCAS 146-48-5Aphrodine; Quebrachine; CorynineAlkaloid (Indole)YohimbePausinystalia yohimbeBarkModerateAn alpha-2 adrenergic antagonist studied for effects on fat mobilisation and sexual function; associated with cardiovascular and anxiety side effects at higher doses.
CorynantheineCAS 6877-32-3Yohimbe alkaloid; Indole alkaloidAlkaloid (Indole)YohimbePausinystalia yohimbeBarkEmergingStudied for vascular receptor-blocking activity; may contribute to the blood flow-modulating properties of yohimbe bark alongside yohimbine.
CorynanthineCAS 483-10-3Alpha-Yohimbine isomer; RauhimbineAlkaloid (Indole)YohimbePausinystalia yohimbeBarkModerateStudied as an alpha-1 adrenergic antagonist; may contribute to vasodilatory and blood pressure-modulating effects of yohimbe preparations.
Yohimbinic AcidYohimbine metaboliteAlkaloid (Indole)YohimbePausinystalia yohimbeBarkEmergingThe primary inactive urinary metabolite of yohimbine; used as a biomarker in pharmacokinetic studies of yohimbe alkaloid metabolism.
AkuammineCAS 4880-88-0Picralima seed alkaloid; Kappa-opioid agonistAlkaloid (Indole)AkuammaPicralima nitidaSeedsModerateStudied for kappa-opioid receptor agonism and potential analgesic properties; part of the traditional West African analgesic plant Akuamma.
AkuammidinePicralima alkaloidAlkaloid (Indole)AkuammaPicralima nitidaSeedsEmergingA minor alkaloid studied for mild muscle-relaxant and hypotensive properties in preclinical models.
AkuammicinePicralima opioid alkaloidAlkaloid (Indole)AkuammaPicralima nitidaSeedsEmergingStudied for opioid receptor binding and potential analgesic activity without the respiratory depression associated with classical opioids.
AkuammilinePicralima alkaloid complexAlkaloid (Indole)AkuammaPicralima nitidaSeedsEmergingStudied in early-stage research for anti-inflammatory and analgesic properties in preclinical pain models.
EchitamineCAS 478-94-4Ditaine; Alstonia alkaloidAlkaloid (Indole)Dita BarkAlstonia scholarisTrunk BarkModerateStudied for antipyretic and antispasmodic properties; used traditionally in Southeast Asian medicine for fever management.
AlstonineCAS 642-18-2Alstonia alkaloid; Antipsychotic indoleAlkaloid (Indole)Dita Bark / SnakerootAlstonia scholarisBark / RootsModerateStudied for dopamine receptor-mediated antipsychotic-like properties in animal models; of interest in psychiatric research.
AlstonidineAlstonia minor alkaloidAlkaloid (Indole)Dita BarkAlstonia scholarisBarkEmergingA minor sedative alkaloid from Alstonia; studied for mild CNS depressant and blood pressure-lowering properties.
TetrahydroalstonineCAS 6877-09-4Alstonia hypoglycaemic alkaloidAlkaloid (Indole)Dita BarkAlstonia scholarisBarkModerateStudied for significant hypoglycaemic activity in preclinical models; may support healthy blood glucose management.
EchitamidineAlstonia alkaloidAlkaloid (Indole)Dita BarkAlstonia scholarisBarkEmergingStudied in traditional medicine contexts for antipyretic properties and electrolyte-rebalancing effects during febrile illness.
LeurosineCAS 23360-92-1Vinca alkaloid dimer; VLRAlkaloid (Indole)Madagascar PeriwinkleCatharanthus roseusLeavesModerateClosely related to vinblastine; studied for antimitotic properties. Less clinically studied than its relatives due to higher toxicity profile.
VindolinineCAS 4490-60-6Catharanthus minor alkaloidAlkaloid (Indole)Madagascar PeriwinkleCatharanthus roseusLeavesModerateStudied for moderate hypoglycaemic activity in animal models; may contribute to the traditional use of periwinkle for blood sugar support.
CatharineVinca complex dimerAlkaloid (Indole)Madagascar PeriwinkleCatharanthus roseusLeavesEmergingA minor dimeric vinca alkaloid studied primarily in botanical mapping and natural product chemistry research.
Catharanthinic AcidVinca alkaloid intermediateAlkaloid (Indole)Madagascar PeriwinkleCatharanthus roseusLeavesEmergingA biosynthetic intermediate in the assembly of complex antimitotic vinca alkaloids; of interest in metabolic pathway engineering.
IbogamineCAS 3484-55-7Iboga minor alkaloidAlkaloid (Indole)IbogaTabernanthe ibogaRoot BarkEmergingA minor iboga alkaloid studied for anticonvulsant properties in animal models; contributes to the broader neurological activity of iboga root bark.
TabernanthineCAS 4880-92-6Iboga alkaloid; CNS depressantAlkaloid (Indole)IbogaTabernanthe ibogaRoot BarkEmergingStudied for heart rate-lowering and analgesic effects; a minor alkaloid of the iboga complex with lower potency than ibogaine.
IbogalineIboga minor alkaloidAlkaloid (Indole)IbogaTabernanthe ibogaRoot BarkEmergingA minor constituent of iboga root bark; contributes to the plant's complex neurological defence chemistry.
VoacangineCAS 83-34-1Voacanga alkaloid; Ibogaine precursorAlkaloid (Indole)VoacangaVoacanga africanaBark / SeedsModerateA biosynthetic precursor used in the semi-synthesis of ibogaine and related anti-addiction compounds; studied for mild analgesic properties.
CoronaridineCAS 467-77-6Iboga-type alkaloidAlkaloid (Indole)VoacangaVoacanga africanaBark / RootsModerateStudied for analgesic properties and potential to reduce addictive drug-seeking behaviour in animal models.
ConopharyngineVoacanga alkaloidAlkaloid (Indole)VoacangaVoacanga africanaBarkEmergingA minor alkaloid from Voacanga; studied for mild CNS stimulant and vasodilatory properties in preliminary research.
TryptamineCAS 61-54-13-(2-Aminoethyl)indole; Biogenic amineAlkaloid (Indole)Acacia / MimosaAcacia / Mimosa spp.Root BarkModerateA trace biogenic amine and biosynthetic precursor to numerous psychoactive tryptamine alkaloids; minor endogenous activity as a trace amine.
N,N-DMTCAS 61-50-7Dimethyltryptamine; PhantasticaAlkaloid (Indole)Jurema PretaMimosa tenuifloraRoot BarkEmergingA potent serotonin receptor agonist associated with profound alterations in sensory perception; subject to controlled substance regulations in most jurisdictions.
BufoteninCAS 487-93-45-Hydroxy-DMT; N,N-Dimethyl-5-hydroxytryptamineAlkaloid (Indole)Yopo TreeAnadenanthera colubrinaSeedsEmergingA serotonergic alkaloid associated with intense cardiovascular stimulation and significant perceptual alterations; subject to controlled substance regulations.
5-MeO-DMTCAS 1019-45-05-Methoxy-N,N-dimethyltryptamineAlkaloid (Indole)VirolaVirola theiodoraBark ResinEmergingAn extremely potent serotonin agonist associated with complete dissociative states; subject to controlled substance regulations in most jurisdictions.
ErvamineTabernaemontana alkaloidAlkaloid (Indole)Crepe JasmineTabernaemontana divaricataLeavesEmergingStudied for acetylcholinesterase inhibitory properties in early-stage research; may contribute to the cognitive-supportive traditional uses of this plant.
ErvatamineCrepe Jasmine alkaloidAlkaloid (Indole)Crepe JasmineTabernaemontana divaricataLeavesEmergingStudied for significant CNS depressant activity in animal models; associated with hypothermia at higher doses in preclinical research.
MacusineCurare alkaloid; Strychnos alkaloidAlkaloid (Indole)Strychnine TreeStrychnos toxiferaBarkEmergingA curare-type alkaloid that blocks neuromuscular junction transmission; of historical interest in anaesthesiology research.
C-ToxiferineCAS 4759-48-2Calabash curare; Neuromuscular blockerAlkaloid (Indole)Strychnine TreeStrychnos toxiferaBarkEmergingOne of the most potent plant-derived neuromuscular blockers; associated with respiratory paralysis at very low doses. Studied historically in anaesthesia pharmacology.
StrychnobrasilineSouth American Strychnos alkaloidAlkaloid (Indole)Strychnine TreeStrychnos brasiliensisBarkEmergingStudied for a complex mix of local muscle-relaxant and mild CNS excitatory effects in preclinical models.
KoumineCAS 1358-76-5Gelsemium minor alkaloidAlkaloid (Indole)Yellow JessamineGelsemium elegansRootsEmergingStudied for non-opioid analgesic properties in animal pain models; associated with promising but early-stage results for chronic pain management.
GelsevirineCAS 1354-84-3Gelsemium toxic alkaloidAlkaloid (Indole)Yellow JessamineGelsemium sempervirensRootsEmergingA highly toxic alkaloid that depresses respiratory centres; documented for toxicological reference. Associated with serious poisoning risk.
SempervirineCAS 6893-02-3Gelsemium alkaloidAlkaloid (Indole)Yellow JessamineGelsemium sempervirensRootsEmergingStudied for potential spinal analgesic properties; high systemic toxicity limits clinical development.
MescalineCAS 54-04-63,4,5-Trimethoxyphenethylamine; Peyote alkaloidAlkaloid (Protoalkaloid)Peyote / San PedroLophophora williamsiiCactus ButtonEmergingA phenethylamine psychedelic studied for interactions with serotonin receptors; associated with profound alterations in perception and cognition. Controlled substance in most jurisdictions.
SecurinineCAS 5610-40-2Norsecurinine; Phyllanthus alkaloidAlkaloid (Indolizidine)SecurinegaSecurinega suffruticosaLeaves / RootsModerateA GABA antagonist studied for CNS stimulant effects and potential support in neurological fatigue conditions; used in traditional Chinese medicine.
AustralineCAS 107439-79-2Cassia alkaloid; Swainsonine analogAlkaloid (Pyrrolizidine)Moreton Bay ChestnutCastanospermum australeSeedsEmergingStudied for selective glycosidase inhibitory activity with potential antiviral applications; part of the indolizidine alkaloid family with distinct properties from hepatotoxic pyrrolizidines.
LentiginosineLocoweed alkaloid; Castanospermine analogAlkaloid (Indolizidine)LocoweedAstragalus lentiginosusLeavesEmergingA specialised glycosidase inhibitor studied for antiviral potential; of interest in cell biology research for its effects on glycoprotein processing.
LycorineCAS 476-28-8Lycoris alkaloid; Narcissus alkaloidAlkaloid (Amaryllidaceae)Spider LilyLycoris radiataBulbsModerateStudied for emetic, antiviral, and antiproliferative properties in preclinical models; associated with moderate cytotoxicity at higher doses.
NarciclasineCAS 29477-83-6Narcissus alkaloid; Growth inhibitorAlkaloid (Amaryllidaceae)DaffodilNarcissus spp.BulbsEmergingStudied for antiproliferative and antifungal properties in laboratory settings; associated with potent phytotoxic activity.
HaemanthamineCAS 466-75-1Blood Lily alkaloidAlkaloid (Amaryllidaceae)Blood LilyHaemanthus spp.BulbsEmergingStudied in early-stage research for its ability to trigger apoptosis in cancer cell lines; preclinical data only.
TazettineCAS 15210-24-9Narcissus alkaloidAlkaloid (Amaryllidaceae)DaffodilNarcissus tazettaBulbsEmergingA mildly cytotoxic Narcissus alkaloid studied for effects on cellular life cycles in laboratory research.
CrinineCAS 480-27-3Crinum alkaloidAlkaloid (Amaryllidaceae)Crinum LilyCrinum asiaticumBulbsEmergingStudied for respiratory stimulant properties in traditional medicine contexts; of research interest for its effects on CNS respiratory centres.
NuciferineCAS 475-83-2Lotus leaf alkaloid; AporphineAlkaloid (Aporphine)Sacred LotusNelumbo nuciferaLeavesModerateStudied for CNS relaxant, antipsychotic-like, and hepatoprotective (lipid-clearing) properties in preclinical research.
NeferineCAS 2292-16-2Lotus seed embryo alkaloidAlkaloid (Bisbenzylisoquinoline)Sacred LotusNelumbo nuciferaSeed EmbryoModerateStudied for calcium channel blocking, antihypertensive, and potential pulmonary antifibrotic properties in preclinical models.
RoemerineLotus aporphine alkaloidAlkaloid (Aporphine)Sacred LotusNelumbo nuciferaLeavesEmergingStudied for antifungal and antimicrobial properties in laboratory settings; contributes to the broader pharmacological profile of lotus leaf preparations.
MagnoflorineCAS 6873-13-8Magnolia quaternary alkaloidAlkaloid (Aporphine)MagnoliaMagnolia officinalisBarkModerateStudied for anxiolytic, cholesterol-oxidation-inhibiting, and anti-neuroinflammatory properties in preclinical models.
BoldineCAS 476-70-0(+)-Boldine; Peumus alkaloidAlkaloid (Aporphine)BoldoPeumus boldusDried LeavesModerateStudied for hepatoprotective, choleretic, and antioxidant properties; supports traditional use for liver and gallbladder health.
IsocorydineCAS 475-67-2Glaucium aporphine alkaloidAlkaloid (Aporphine)Yellow Horned PoppyGlaucium flavumAerial PartsEmergingStudied for vasodilatory and antiproliferative properties in early-stage research; contributes to the traditional use of Glaucium for pain.
CorytuberineCAS 522-89-4Corydalis aporphine alkaloidAlkaloid (Aporphine)CorydalisCorydalis yanhusuoTuberEmergingStudied for strong dopaminergic effects including rigid muscle states in animal models; contributes to the complex pharmacology of Corydalis preparations.
CorydineCAS 476-69-7Corydalis aporphine; CNS depressantAlkaloid (Aporphine)CorydalisCorydalis yanhusuoTuberModerateStudied for analgesic and CNS depressant properties; contributes to the traditional pain-management use of Corydalis alongside THP.
LaurotetanineCAS 6877-32-3Litsea aporphine alkaloidAlkaloid (Aporphine)LitseaLitsea cubebaBark / RootsEmergingStudied for antimicrobial and CNS depressant properties in early-stage laboratory research.
LiriodenineCAS 522-59-8Tulip tree alkaloid; OxoaporphineAlkaloid (Aporphine)Tulip TreeLiriodendron tulipiferaHeartwoodModerateStudied for antimicrobial and antifungal properties; associated with inhibitory effects on fungal cell wall synthesis.
ThalicarpineMeadow Rue aporphineAlkaloid (Aporphine)Meadow RueThalictrum dasycarpumRootsEmergingStudied in early-stage laboratory research for antiproliferative effects on cancer cell lines; preclinical data only.
HernandalineHernandia aporphine alkaloidAlkaloid (Aporphine)HernandiaHernandia nymphaeifoliaBark / LeavesEmergingStudied for smooth muscle relaxant and antihypertensive properties in animal models.
LysicamineLiriodendron oxoaporphineAlkaloid (Aporphine)Tulip TreeLiriodendron tulipiferaHeartwoodEmergingStudied for antifungal and antibacterial properties against soil-borne pathogens in laboratory research.
NandigerineNandina aporphine alkaloidAlkaloid (Aporphine)Heavenly BambooNandina domesticaBerries / RootsEmergingStudied for bronchodilatory effects; associated with significant systemic toxicity if ingested in quantity. Documented for safety reference.
AtherospermidineSassafras aporphine alkaloidAlkaloid (Aporphine)SassafrasSassafras albidumRoots / BarkEmergingStudied for cytotoxic properties in targeted cell line research; preclinical data only.
AnonaineCustard Apple aporphineAlkaloid (Aporphine)Custard AppleAnnona squamosaBark / LeavesEmergingStudied in early-stage laboratory research for antiproliferative effects on cancer cell lines.
TetrandrineCAS 518-34-3Sinomenine-related; BisbenzylisoquinolineAlkaloid (Bisbenzylisoquinoline)StephaniaStephania tetrandraRootsModerateStudied for calcium channel blocking, antihypertensive, and anti-inflammatory properties; multiple preclinical studies and limited human trials for lung conditions.
FangchinolineCAS 33889-69-9Stephania alkaloidAlkaloid (Bisbenzylisoquinoline)StephaniaStephania tetrandraRootsModerateStudied for anticoagulant and antiviral properties in preclinical models; may complement the pharmacological profile of Stephania root.
DauricineCAS 524-17-4Asian Moonseed alkaloidAlkaloid (Bisbenzylisoquinoline)Asian MoonseedMenispermum dauricumRhizomesModerateStudied for antiarrhythmic properties and potential protection of cardiac tissue during ischaemic stress; preclinical data available.
ThalidasineMeadow Rue bisbenzylAlkaloid (Bisbenzylisoquinoline)Meadow RueThalictrum dasycarpumRootsEmergingStudied for potential anti-angiogenic properties that may limit blood supply to tumour tissue; early-stage laboratory research only.
IsochondodendrineCAS 6871-44-9Curare-related alkaloidAlkaloid (Bisbenzylisoquinoline)Curare VineChondrodendron tomentosumBarkEmergingA structural relative of tubocurarine studied for mild non-lethal neuromuscular relaxant properties; of historical pharmacological interest.
ChondrocurarineTubocurarine-type; Curare alkaloidAlkaloid (Bisbenzylisoquinoline)Curare VineChondrodendron tomentosumBarkEmergingA potent neuromuscular blocking alkaloid; associated with respiratory paralysis. Documented for toxicological and pharmacological reference only.
CissampareineCissampelos bisbenzylAlkaloid (Bisbenzylisoquinoline)VelvetleafCissampelos pareiraRootsEmergingStudied for uterine smooth muscle relaxant properties; of interest for research into preterm labour management. Preclinical data only.
StepholidineStephania protoberberineAlkaloid (Protoberberine)StephaniaStephania intermediaRoots / TubersModerateStudied for dopamine D1/D2 receptor modulation; of interest in research into movement disorders and antipsychotic pharmacology.
TROPANE ALKALOIDS
AtropineCAS 51-55-8dl-Hyoscyamine; dl-Tropyl tropateAlkaloid (Tropane)Deadly NightshadeAtropa belladonnaLeaves and RootsHighA clinically established anticholinergic used medically as a pre-anaesthetic, antispasmodic, and antidote to organophosphate poisoning.
ScopolamineCAS 51-34-3Hyoscine; Transderm ScopAlkaloid (Tropane)Jimson WeedDatura stramoniumSeeds and LeavesHighA clinically established anticholinergic used medically for motion sickness, pre-anaesthetic sedation, and nausea management.
CocaineCAS 50-36-2Benzoylmethylecgonine; CokeAlkaloid (Tropane)CocaErythroxylum cocaLeavesHighA potent local anaesthetic and sympathomimetic; the first clinically used local anaesthetic. Associated with significant addiction and cardiovascular toxicity. Controlled substance.
HyoscyamineCAS 101-31-5L-Hyoscyamine; LevsinAlkaloid (Tropane)HenbaneHyoscyamus nigerLeavesHighA clinically used anticholinergic that relieves smooth muscle spasms of the gastrointestinal and urinary tracts.
EcgonineCAS 481-37-8Cocaine backbone; Tropane acidAlkaloid (Tropane)CocaErythroxylum cocaLeavesEmergingThe primary structural core of cocaine; lacks potent CNS stimulant activity on its own. Of interest in forensic toxicology.
CinnamoylcocaineCAS 521-64-2Coca minor alkaloidAlkaloid (Tropane)CocaErythroxylum cocaLeavesEmergingA secondary coca alkaloid with mild local anaesthetic and stimulant properties; contributes to the complex alkaloid profile of coca leaf.
TropacocaineCAS 537-26-8Coca minor alkaloidAlkaloid (Tropane)CocaErythroxylum cocaLeavesEmergingStudied for local anaesthetic properties with a faster onset but shorter duration than cocaine; of primarily pharmacological research interest.
PseudotropineCAS 135-97-7Tropine isomer; Tropane precursorAlkaloid (Tropane)Deadly NightshadeAtropa belladonnaRootsEmergingA biosynthetic intermediate in the production of tropane alkaloids; lacks the potent pharmacological activity of atropine or scopolamine.
BelladonnineAtropa minor alkaloidAlkaloid (Tropane)Deadly NightshadeAtropa belladonnaLeavesEmergingA minor tropane alkaloid from Atropa belladonna; associated with strong mydriatic and smooth muscle-paralysing effects at low doses. Toxic — documented for reference.
Calystegine A3CAS 117275-05-5Polyhydroxy tropane; IminosugarAlkaloid (Tropane)Potato / BindweedSolanum tuberosumRoots / TubersEmergingStudied as a glycosidase inhibitor that may influence carbohydrate metabolism; present at trace levels in common dietary plants.
PURINE ALKALOIDS
CaffeineCAS 58-08-21,3,7-Trimethylxanthine; GuaranineAlkaloid (Purine)Coffee / Tea PlantCoffea arabica / Camellia sinensisDried Seeds / LeavesHighAn adenosine receptor antagonist that increases alertness and reduces fatigue; well-documented in human trials for cognitive and physical performance support.
TheobromineCAS 83-67-03,7-Dimethylxanthine; Cacao alkaloidAlkaloid (Purine)CacaoTheobroma cacaoSeeds (Beans)HighA mild CNS stimulant and bronchodilator; studied for cardiovascular effects including vasodilation and positive inotropic activity. Lower CNS potency than caffeine.
TheophyllineCAS 58-55-91,3-Dimethylxanthine; Aminophylline precursorAlkaloid (Purine)Tea PlantCamellia sinensisLeavesHighA clinically used bronchodilator for asthma and COPD management; relaxes airway smooth muscle via phosphodiesterase inhibition.
MethylliberineDynamine; Kucha tea alkaloidAlkaloid (Purine)Kucha TeaCamellia assamicaLeavesEmergingStudied for rapid-onset CNS stimulation with a potentially lower cardiovascular burden than caffeine; early-stage human research is limited.
ParaxanthineCAS 611-59-61,7-Dimethylxanthine; Caffeine metaboliteAlkaloid (Purine)CoffeeCoffea arabicaSeedsModerateThe primary human metabolic product of caffeine; studied for lipolytic and muscular endurance-enhancing properties independent of caffeine.
PYRIDINE & PIPERIDINE ALKALOIDS
NicotineCAS 54-11-53-(1-Methylpyrrolidin-2-yl)pyridine; Tabacum alkaloidAlkaloid (Pyridine)TobaccoNicotiana tabacumLeavesHighAn acetylcholinergic stimulant; pharmacologically well-characterised. Associated with significant cardiovascular and addictive effects. Controlled in many jurisdictions.
PiperineCAS 94-62-21-Piperoylpiperidine; Black Pepper amideAlkaloid (Piperidine)Black PepperPiper nigrumDried FruitsHighWell-documented as a bioavailability enhancer; may inhibit P-glycoprotein and CYP3A4 to increase absorption of co-administered compounds including curcumin.
LobelineCAS 90-69-7Lobelamine; Lobelia alkaloidAlkaloid (Piperidine)Indian TobaccoLobelia inflataDried Whole PlantModerateStudied as a nicotinic receptor partial agonist; historically used as a smoking cessation aid and expectorant. Limited modern clinical evidence.
ArecolineCAS 63-75-2Betel nut alkaloid; Methyl arecaidinateAlkaloid (Pyridine)Betel NutAreca catechuSeedsModerateA muscarinic and nicotinic agonist producing CNS stimulation; associated with significant long-term cardiovascular and oral carcinogenicity risks with habitual use.
GuvacineGABA reuptake inhibitor; Betel nut alkaloidAlkaloid (Pyridine)Betel NutAreca catechuSeedsEmergingA GABA transporter inhibitor that may produce mild CNS stimulation and nervous tension; contributes to the overall pharmacology of betel nut chewing.
AnabasineCAS 494-52-0beta-Pyridyl piperidine; Tree tobaccoAlkaloid (Pyridine)Tree TobaccoNicotiana glaucaLeavesModerateA botanical nicotinic receptor agonist with insecticidal properties; associated with toxicity in mammals at higher doses.
AnatabineCAS 581-49-7Minor tobacco alkaloidAlkaloid (Pyridine)TobaccoNicotiana tabacumLeavesModerateStudied for anti-inflammatory properties in preclinical models; may support neurological pathway protection. Limited human data available.
TrigonellineCAS 535-83-1N-Methylnicotinic acid; CoffearineAlkaloid (Pyridine)FenugreekTrigonella foenum-graecumSeedsModerateStudied for support of healthy blood glucose metabolism and potential neuroprotective properties; present in significant amounts in coffee and fenugreek.
RicinineCAS 524-40-3Castor bean alkaloid; N-methyl-3-cyano-4-methoxy-2-pyridoneAlkaloid (Pyridine)Castor BeanRicinus communisSeedsEmergingA mildly neurotoxic plant defence alkaloid; present at low levels in castor bean. Of interest primarily in toxicology and agricultural pest control research.
PelletierineCAS 4396-01-4Punicine; Pomegranate root alkaloidAlkaloid (Piperidine)PomegranatePunica granatumRoot BarkModerateStudied for anthelmintic (parasite-expelling) properties; historically used in traditional medicine to address intestinal parasites. Toxic at high doses.
ConiineCAS 458-88-82-Propylpiperidine; Hemlock alkaloidAlkaloid (Piperidine)Poison HemlockConium maculatumSeedsEmergingA potent neurotoxin that causes ascending motor paralysis by blocking nicotinic acetylcholine receptors. Lethal at low doses. Documented for toxicological reference only.
PiperlongumineCAS 20069-09-4Piplartine; Long pepper alkaloidAlkaloid (Pyridine)Long PepperPiper longumRoots / FruitEmergingStudied for selective antiproliferative effects on cancer cells via oxidative stress induction; early-stage laboratory and animal research only.
QUINOLINE ALKALOIDS
QuinineCAS 130-95-0Quininum; Malaria treatmentAlkaloid (Quinoline)Cinchona TreeCinchona officinalisDried Trunk BarkHighA clinically established antimalarial; inhibits haem polymerisation in Plasmodium. Also used medically for nocturnal leg cramps under supervision.
QuinidineCAS 56-54-2Quinidex; Class Ia antiarrhythmicAlkaloid (Quinoline)Cinchona TreeCinchona officinalisTrunk BarkHighA clinically used antiarrhythmic; stabilises cardiac electrical conduction. Administered medically under monitoring due to proarrhythmic risk.
CinchonineCAS 118-10-5Cinchona alkaloid; AntimalarialAlkaloid (Quinoline)Cinchona TreeCinchona pubescensTrunk BarkModerateAn antimalarial alkaloid that disrupts haemozoin formation in malarial parasites; less studied clinically than quinine but with a similar mechanism.
CamptothecinCAS 7689-03-4CPT; Camptotheca alkaloidAlkaloid (Quinoline)Happy TreeCamptotheca acuminataBark and FruitHighA topoisomerase I inhibitor that formed the basis for the clinically approved anticancer drugs irinotecan and topotecan.
HydroquinineCAS 522-66-7Quinine minor; Cinchona alkaloidAlkaloid (Quinoline)Cinchona TreeCinchona officinalisBarkModerateA minor cinchona alkaloid with antimalarial properties; studied as a reference compound in Plasmodium biochemistry research.
CupreineCAS 524-63-0Cinchotannic alkaloidAlkaloid (Quinoline)Cinchona TreeCinchona cupreaBarkModerateA structural relative of quinine used as a chiral organocatalyst in pharmaceutical synthesis; studied for antimalarial activity.
QuinicineQuinine thermolysis productAlkaloid (Quinoline)Cinchona TreeCinchona officinalisBarkEmergingA heat-degraded isomer of quinine with reduced antimalarial efficacy; of analytical and toxicological interest in cinchona bark preparations.
CinchonamineCinchona indole alkaloidAlkaloid (Indole)Cinchona TreeCinchona pubescensBarkEmergingA minor indole-type alkaloid from Cinchona bark with mild antimalarial and CNS properties; less studied than the major cinchona alkaloids.
DictamnineCAS 484-29-7Burning Bush quinolineAlkaloid (Quinoline)Burning BushDictamnus albusRoots / BarkModerateStudied for smooth muscle stimulant and localised antimicrobial properties; contributes to the traditional skin and digestive uses of Dictamnus.
SkimmianineCAS 83-95-4Japanese Skimmia alkaloidAlkaloid (Quinoline)Japanese SkimmiaSkimmia japonicaLeavesModerateStudied for CNS depressant and skeletal muscle-relaxant properties in preclinical models; contributes to the traditional calming use of Skimmia.
STEROIDAL ALKALOIDS
SolanineCAS 20562-02-1Alpha-Solanine; Potato glycoalkaloidAlkaloid (Steroidal)PotatoSolanum tuberosumGreen Skin / SproutsModerateA natural pesticide alkaloid toxic to insects and, at elevated levels, to humans; associated with cholinesterase inhibition and gastrointestinal distress. Levels are regulated in food potatoes.
ChaconineCAS 20562-03-2Alpha-Chaconine; Potato glycoalkaloidAlkaloid (Steroidal)PotatoSolanum tuberosumGreen Skin / SproutsModerateA glycoalkaloid that works in combination with solanine as a natural pest deterrent; associated with neurotoxic effects at high intake levels.
TomatineCAS 17406-45-0Alpha-Tomatine; Tomato glycoalkaloidAlkaloid (Steroidal)TomatoSolanum lycopersicumGreen Fruit / LeavesModerateA steroidal glycoalkaloid studied for antifungal activity and potential antiproliferative effects; mildly toxic to humans at very high intake.
SolasodineCAS 126-17-0Solanum steroidal alkaloid; Hormone precursorAlkaloid (Steroidal)Devil's AppleSolanum linnaeanumFruitModerateA steroidal alkaloid used industrially as a starting material for the synthesis of pharmaceutical steroid hormones and contraceptives.
SolamargineCAS 6956-26-3Solanum glycoalkaloidAlkaloid (Steroidal)Devil's AppleSolanum linnaeanumFruitEmergingStudied for antiproliferative and apoptosis-inducing properties in cancer cell lines in early-stage laboratory research.
SolasonineCAS 19121-58-5Solanum glycoalkaloidAlkaloid (Steroidal)Devil's AppleSolanum linnaeanumFruitEmergingStudied alongside solamargine for antimicrobial and antiproliferative properties in laboratory research.
CyclopamineCAS 4449-51-811-deoxojervine; Hedgehog inhibitorAlkaloid (Steroidal)Corn LilyVeratrum californicumRootsEmergingA teratogenic Hedgehog signalling pathway inhibitor; studied in oncology research as a basis for targeted cancer therapies.
JervineCAS 469-59-0Veratrum teratogen; Steroidal alkaloidAlkaloid (Steroidal)Corn LilyVeratrum californicumRootsEmergingA highly teratogenic steroidal alkaloid that disrupts CNS development; associated with serious foetal malformations. Documented for toxicological reference only.
VeratramineCAS 60-70-8False Hellebore alkaloidAlkaloid (Steroidal)False HelleboreVeratrum virideRhizomesEmergingHighly toxic steroidal alkaloid associated with severe cardiovascular depression and CNS toxicity. Documented for toxicological reference only.
ConessineCAS 546-06-5Holarrhena alkaloid; Steroidal antibioticAlkaloid (Steroidal)KurchiHolarrhena pubescensBarkModerateStudied for specific amoebicidal activity against Entamoeba histolytica; used traditionally for severe dysentery treatment.
HolarrhenineKurchi steroidal alkaloidAlkaloid (Steroidal)KurchiHolarrhena pubescensBarkModerateA steroidal alkaloid from the same source as conessine; studied for complementary amoebicidal properties.
PeimineCAS 18059-10-4Fritillary steroidal alkaloidAlkaloid (Steroidal)Fritillary BulbFritillaria thunbergiiBulbsModerateStudied for expectorant and mucolytic properties; supports the traditional use of Fritillary bulb in respiratory wellness.
PeiminineCAS 18059-10-4Delavaine; Fritillary alkaloidAlkaloid (Steroidal)Fritillary BulbFritillaria thunbergiiBulbsModerateStudied for anti-inflammatory and antitussive properties; may support soothing of throat mucosal irritation.
ImperialineCAS 18059-10-4Sipeimine; Fritillary alkaloidAlkaloid (Steroidal)Fritillary BulbFritillaria imperialisBulbsModerateStudied for bronchial smooth muscle-relaxing properties; may support relief from bronchospasm in respiratory conditions.
VerticineThujifoline; Fritillary alkaloidAlkaloid (Steroidal)Fritillary BulbFritillaria verticillataBulbsModerateStudied for anti-inflammatory and immunomodulatory properties in the context of pulmonary health support.
VerticinoneFritillary alkaloidAlkaloid (Steroidal)Fritillary BulbFritillaria verticillataBulbsModerateStudied alongside verticine for antitussive and expectorant effects; used in traditional Chinese medicine for respiratory conditions.
DemissineCAS 28754-79-0Wild potato glycoalkaloidAlkaloid (Steroidal)Wild PotatoSolanum demissumLeavesEmergingA defensive steroidal glycoalkaloid with insecticidal activity; mildly toxic to mammals at elevated doses.
SolanocapsineCAS 13956-28-0Jerusalem Cherry alkaloidAlkaloid (Steroidal)Jerusalem CherrySolanum pseudocapsicumFruitEmergingA highly toxic steroidal alkaloid associated with severe gastrointestinal and CNS toxicity if the raw fruit is consumed; documented for safety reference.
PYRROLIZIDINE ALKALOIDS
SenecionineCAS 130-01-8Senecio PA; Hepatotoxic pyrrolizidineAlkaloid (Pyrrolizidine)RagwortSenecio jacobaeaLeavesEmergingA hepatotoxic unsaturated pyrrolizidine alkaloid; associated with irreversible veno-occlusive liver disease. Strictly a toxicological reference compound — not for therapeutic use.
MonocrotalineCAS 315-22-0Crotalaria PA; Pulmonary toxinAlkaloid (Pyrrolizidine)RattleboxCrotalaria spectabilisSeedsEmergingHighly toxic to pulmonary vascular tissue; used experimentally in research models of pulmonary arterial hypertension. Not therapeutically used.
RetrorsineCAS 480-54-6Senecio genotoxinAlkaloid (Pyrrolizidine)RagwortSenecio isatideusAerial PartsEmergingAn unsaturated pyrrolizidine alkaloid that cross-links hepatocyte DNA, preventing cell division; documented for toxicological reference only.
LasiocarpineCAS 303-34-4Heliotrope PA; Liver carcinogenAlkaloid (Pyrrolizidine)HeliotropeHeliotropium europaeumLeavesEmergingA potent hepatotoxic and genotoxic pyrrolizidine alkaloid associated with permanent liver damage and classified as a possible human carcinogen. Toxicological reference only.
SymphytineCAS 22257-23-4Comfrey PA; HepatotoxinAlkaloid (Pyrrolizidine)ComfreySymphytum officinaleRootsEmergingA hepatotoxic pyrrolizidine alkaloid found in comfrey root; the reason internal comfrey preparations are subject to regulatory limits in many countries.
LycopsamineCAS 10285-07-1Borage PA; HepatotoxinAlkaloid (Pyrrolizidine)BorageBorago officinalisLeavesEmergingAn unsaturated pyrrolizidine alkaloid present in borage; associated with liver toxicity at high intake levels. Regulatory monitoring is applied to borage food products.
IntermedineComfrey PA; HepatotoxinAlkaloid (Pyrrolizidine)ComfreySymphytum officinaleRootsEmergingA pyrrolizidine alkaloid associated with hepatic veno-occlusive disease in humans following internal use; toxicological reference compound.
EchimidineEchium PA; DNA cross-linkerAlkaloid (Pyrrolizidine)Viper's BuglossEchium vulgareAerial PartsEmergingA highly hepatotoxic pyrrolizidine alkaloid associated with DNA cross-linking and liver cell death; of concern as a food contaminant in honey and herbal teas.
RiddelliineCAS 23246-96-0Senecio genotoxin; PAAlkaloid (Pyrrolizidine)Riddell's RagwortSenecio riddelliiWhole PlantEmergingA genotoxic pyrrolizidine alkaloid listed as a possible human carcinogen; documented for toxicological research reference.
HeliotrineCAS 520-69-4Heliotropium PA; Liver toxinAlkaloid (Pyrrolizidine)HeliotropeHeliotropium europaeumLeavesEmergingCauses hepatic necrosis and has been associated with human poisoning through contaminated grain. Isolated for toxicological and agricultural safety research.
PlatyphyllineCAS 480-77-3Senecio antispasmodic PAAlkaloid (Pyrrolizidine)Broadleaf RagwortSenecio platyphyllusLeavesModerateA saturated pyrrolizidine alkaloid with relatively low hepatotoxicity compared to unsaturated congeners; studied for mild antispasmodic properties.
SenkirkineCAS 2318-18-5Coltsfoot PA; HepatotoxinAlkaloid (Pyrrolizidine)ColtsfootTussilago farfaraLeavesEmergingA hepatotoxic pyrrolizidine alkaloid responsible for regulatory restrictions on internal coltsfoot use in several countries.
RosmarinineSenecio PAAlkaloid (Pyrrolizidine)SenecioSenecio rosmarinifoliusAerial PartsEmergingA pyrrolizidine alkaloid associated with disruption of cell division; monitored as an agricultural and food safety concern.
AngustifolineCAS 486-89-5Narrow-leaf Lupin PAAlkaloid (Quinolizidine)Narrow-leaf LupinLupinus angustifoliusSeedsEmergingA bitter quinolizidine alkaloid that deters insect feeding; associated with CNS depression in livestock. Present in food lupins below regulated thresholds.
QUINOLIZIDINE ALKALOIDS
MatrineCAS 519-02-8Sophora alkaloid; QuinolizidineAlkaloid (Quinolizidine)Ku ShenSophora flavescensDried RootsModerateStudied for anti-inflammatory and immunomodulatory properties; used in traditional Chinese medicine and subject to ongoing clinical investigation for liver conditions.
OxymatrineCAS 16837-52-8Sophora N-oxide; Ku Shen alkaloidAlkaloid (Quinolizidine)Sophora RootSophora flavescensRootsModerateStudied for antiviral and hepatoprotective properties; multiple Chinese clinical trials available though study quality is variable.
SophoridineCAS 6882-68-4Sophora antitumour alkaloidAlkaloid (Quinolizidine)Sophora RootSophora flavescensRootsModerateStudied for antiproliferative and anti-inflammatory properties in preclinical cancer research; of interest in Chinese oncology research.
SophoramineCAS 6837-24-7Sophora hepatoprotective alkaloidAlkaloid (Quinolizidine)Sophora RootSophora flavescensRootsModerateStudied for hepatoprotective effects during chemically induced and viral hepatic stress in animal models.
CytisineCAS 485-35-8Baptitoxine; Sophorine; TabexAlkaloid (Quinolizidine)Golden Rain TreeLaburnum anagyroidesSeedsHighA nicotinic receptor partial agonist; clinically used in Eastern Europe as a smoking cessation aid with a favourable evidence base from randomised controlled trials.
SparteineCAS 90-39-1Lupinidine; Scotch Broom alkaloidAlkaloid (Quinolizidine)Scotch BroomCytisus scopariusBranchesModerateA sodium and potassium channel blocker studied for antiarrhythmic and oxytocic properties; used traditionally for obstetric support and cardiac dysrhythmia.
LupanineCAS 550-90-3Lupin bitter alkaloidAlkaloid (Quinolizidine)LupinLupinus albusSeedsModerateThe primary bitter alkaloid of lupin seeds; associated with respiratory depression at high doses. Levels are strictly reduced by debittering processes in food lupins.
AnagyrineCAS 486-89-5Lupin teratogen; QuinolizidineAlkaloid (Quinolizidine)LupinLupinus spp.SeedsEmergingA teratogenic quinolizidine alkaloid associated with foetal limb defects in livestock; documented for safety reference.
N-MethylcytisineCAS 486-86-2Caulophylline; Blue Cohosh alkaloidAlkaloid (Quinolizidine)Blue CohoshCaulophyllum thalictroidesRootsModerateA nicotinic agonist that stimulates uterine contractions; used traditionally to induce labour but associated with significant cardiovascular risk — not recommended without medical supervision.
ThermopsineFalse Lupin toxic alkaloidAlkaloid (Quinolizidine)False LupinThermopsis rhombifoliaSeeds / LeavesEmergingA highly toxic quinolizidine alkaloid associated with severe gastrointestinal and respiratory toxicity in livestock and humans. Documented for toxicological reference.
DITERPENE ALKALOIDS
AconitineCAS 302-27-2Acetylbenzoylaconine; Monkshood alkaloidAlkaloid (Diterpene)MonkshoodAconitum napellusDried RootsModerateA potent sodium channel activator associated with severe neurotoxicity and cardiac arrhythmias at very low doses; used in trace amounts in processed traditional preparations (Aconiti Radix Praeparata) for nerve pain management under strict supervision.
MesaconitineCAS 2752-64-9Aconite alkaloid; Aconitum carmichaeliiAlkaloid (Diterpene)MonkshoodAconitum carmichaeliiRootsModerateExtremely potent neurotoxin; associated with fatal arrhythmias in raw form. Used in traditional formulations after extensive thermal processing under strict supervision.
HypaconitineCAS 6900-87-4Aconite minor alkaloidAlkaloid (Diterpene)MonkshoodAconitum carmichaeliiRootsEmergingA highly toxic aconite alkaloid; associated with potent anti-inflammatory and analgesic effects at strictly controlled trace doses in traditional formulations only.
LappaconitineCAS 32854-75-4Aconite non-narcotic analgesicAlkaloid (Diterpene)MonkshoodAconitum septentrionaleRootsModerateA sodium channel blocker studied for non-opioid analgesic properties; a pharmaceutical version is used clinically in Russia for pain management.
SongorineCAS 2752-65-0Aconitum CNS stimulant alkaloidAlkaloid (Diterpene)MonkshoodAconitum soongaricumTubersEmergingA unique Aconitum alkaloid with a distinctly lower toxicity profile than aconitine; studied for CNS stimulant and potential analgesic properties.
BikhaconitineHimalayan Aconite neurotoxinAlkaloid (Diterpene)Himalayan MonkshoodAconitum spicatumRootsEmergingAn extremely potent neurotoxin that persistently opens voltage-gated sodium channels; associated with rapidly fatal arrhythmias. Documented for toxicological reference only.
PseudaconitineCAS 6831-43-2Nepal Aconite; Most toxic AconitumAlkaloid (Diterpene)Nepal AconiteAconitum feroxRootsEmergingOne of the most potent plant alkaloid toxins known; associated with complete respiratory paralysis at very small doses. Documented for toxicological reference only.
IndaconitineChasmanthum Aconite alkaloidAlkaloid (Diterpene)MonkshoodAconitum chasmanthumRootsEmergingA neurotoxic aconitine-type alkaloid; associated with severe peripheral and central nervous system toxicity. Documented for toxicological reference.
PROTOALKALOIDS & PHENYLETHYLAMINES
EphedrineCAS 299-42-3L-Ephedrine; Ma Huang alkaloidAlkaloid (Protoalkaloid)Ma HuangEphedra sinicaGreen TwigsHighA clinically established sympathomimetic bronchodilator and decongestant; used medically but subject to regulatory controls due to potential for misuse.
PseudoephedrineCAS 90-82-4D-Pseudoephedrine; SudafedAlkaloid (Protoalkaloid)Ma HuangEphedra sinicaStemsHighA clinically used nasal decongestant that acts as a vasoconstrictive sympathomimetic; widely available as an OTC medication but regulated as a precursor.
CathineCAS 492-39-7Norpseudoephedrine; D-NorpseudoephedrineAlkaloid (Protoalkaloid)KhatCatha edulisFresh LeavesModerateA mild sympathomimetic with appetite-suppressing effects; controlled substance in most Western jurisdictions.
CathinoneCAS 71031-15-7S-(-)-Cathinone; Khat primary stimulantAlkaloid (Protoalkaloid)KhatCatha edulisFresh LeavesModerateThe primary psychoactive amphetamine-like alkaloid of khat; associated with significant dopaminergic stimulation and dependence risk. Controlled substance.
HordenineCAS 539-15-1N,N-Dimethyltyramine; Barley alkaloidAlkaloid (Protoalkaloid)BarleyHordeum vulgareGerminating RootsModerateStudied for norepinephrine-releasing activity producing brief physical energy enhancement; present in germinating grains and beer.
SynephrineCAS 94-07-5Para-Synephrine; Bitter orange alkaloidAlkaloid (Protoalkaloid)Bitter OrangeCitrus aurantiumFruit PeelModerateStudied for thermogenic and lipolytic effects; used in weight management supplements. Associated with cardiovascular effects at high doses — regulatory caution applies.
ColchicineCAS 64-86-8Colchicum alkaloid; NSF inhibitorAlkaloid (Protoalkaloid)Autumn CrocusColchicum autumnaleSeeds and CormsHighA clinically approved tubulin-binding anti-inflammatory used medically for acute gout attacks and familial Mediterranean fever management.
QUINAZOLINE & OTHER ALKALOIDS
GalegineCAS 543-19-5Isoamylene guanidine; Metformin precursorAlkaloid (Guanidine)Goat's RueGalega officinalisAerial PartsModerateThe botanical compound that inspired the development of metformin; studied for glucose-lowering effects via cellular glucose uptake enhancement.
VasicinoneCAS 486-64-6Adhatoda quinazoline alkaloidAlkaloid (Quinazoline)Malabar NutAdhatoda vasicaLeavesModerateStudied for bronchodilatory and mucolytic properties; supports the traditional and clinical use of Adhatoda for respiratory conditions.
DeoxyvasicinoneVasicinone analog; Adhatoda alkaloidAlkaloid (Quinazoline)Malabar NutAdhatoda vasicaLeavesModerateStudied for synergistic bronchodilatory and mucus-clearing properties alongside vasicinone in respiratory health preparations.
PilocarpineCAS 92-13-7Jaborandi alkaloid; Imidazole alkaloidAlkaloid (Imidazole)JaborandiPilocarpus jaborandiLeavesHighA clinically established parasympathomimetic used medically for glaucoma management (reducing intraocular pressure) and xerostomia.
IsopilocarpineCAS 492-72-8Pilocarpine isomer; JaborandiAlkaloid (Imidazole)JaborandiPilocarpus jaborandiLeavesEmergingA structural isomer of pilocarpine with weaker parasympathetic stimulation; separated during pharmaceutical purification of pilocarpine.
IsopilosineJaborandi minor alkaloidAlkaloid (Imidazole)JaborandiPilocarpus jaborandiLeavesEmergingA minor alkaloid from Jaborandi with mild ophthalmic activity; typically removed during pharmaceutical-grade pilocarpine production.
LigustrazineCAS 1124-11-4Tetramethylpyrazine; TMP; Ligusticum alkaloidAlkaloid (Pyrazine)ChuanxiongLigusticum chuanxiongRhizomeModerateStudied for vasodilatory and antiplatelet effects that may support cerebral and cardiovascular blood flow; used clinically in China as an injectable.
KifunensineCAS 109001-77-6Glycosidase research toolAlkaloid (Indolizidine)ActinobacteriumKitasatospora kifunensisCellular MatrixEmergingA highly selective alpha-mannosidase I inhibitor used strictly in laboratory research to study glycoprotein processing and N-glycan remodelling.
SlaframineCAS 15973-24-3Black Patch Fungus salivogenAlkaloid (Indolizidine)Black Patch FungusRhizoctonia leguminicolaFungal CellsEmergingA parasympathomimetic mycotoxin that causes excessive salivation in livestock via overstimulation of muscarinic receptors; of agricultural and toxicological research interest.
CapsaicinCAS 404-86-48-Methyl-N-vanillyl-6-nonenamide; VanilloidAlkaloid (Pseudoalkaloid)Chili PepperCapsicum annuumFruit and SeedsHighA TRPV1 receptor agonist with well-documented topical analgesic applications; supported by clinical evidence for localised pain management in neuropathy and musculoskeletal conditions.
ErgocristineCAS 511-08-0Ergot alkaloid; VasoconstrictorAlkaloid (Indole)Ergot FungusClaviceps purpureaSclerotiumModerateAn ergopeptine vasoconstrictor studied for uterine and vascular smooth muscle effects; part of the pharmacologically complex ergot alkaloid family.
ErgocryptineCAS 561-78-4Ergot alkaloid; DopaminergicAlkaloid (Indole)Ergot FungusClaviceps purpureaSclerotiumModerateStudied for dopamine receptor interactions; forms the biological basis for the development of dopaminergic drugs used in Parkinson's disease management.
ErgosineCAS 561-94-4Ergot toxic alkaloidAlkaloid (Indole)Ergot FungusClaviceps purpureaSclerotiumModerateAn ergot alkaloid associated with peripheral vasoconstriction; part of the toxic alkaloid complex responsible for ergotism. Documented for safety reference.
ErgocornineCAS 564-36-3Ergot alkaloid; Migraine researchAlkaloid (Indole)Ergot FungusClaviceps purpureaSclerotiumModerateAn ergopeptine that causes potent peripheral vasoconstriction; studied in the context of migraine management research.
ErgonovineCAS 60-79-7Ergobasine; Ergometrine; Obstetric ergotAlkaloid (Indole)Ergot FungusClaviceps purpureaSclerotiumHighA clinically used uterotonic that selectively contracts uterine smooth muscle; used medically to prevent and treat postpartum haemorrhage under clinical supervision.
ErgotaminineCAS 639-81-6Ergotamine isomer; Inactive ergotAlkaloid (Indole)Ergot FungusClaviceps purpureaSclerotiumEmergingThe biologically inactive epimer of ergotamine; used as an analytical reference marker during pharmaceutical isolation of active ergot alkaloids.
FLAVONOLS
QuercetinCAS 117-39-53,3',4',5,7-Pentahydroxyflavone; SophoretinPolyphenol (Flavonol)Red OnionAllium cepaOuter Bulb ScalesModerateA widely studied dietary flavonol; may support normal antioxidant defence and healthy inflammatory balance. Some evidence for mast cell stabilisation relevant to seasonal allergies.
KaempferolCAS 520-18-33,4',5,7-TetrahydroxyflavonePolyphenol (Flavonol)BroccoliBrassica oleraceaFloretsModerateStudied for anti-inflammatory and antioxidant properties; may contribute to cardiovascular protection and healthy cell cycle regulation when consumed in plant-rich diets.
FisetinCAS 528-48-33,3',4',7-Tetrahydroxyflavone; FisteinPolyphenol (Flavonol)StrawberryFragaria ananassaFruitModerateStudied for senolytic properties and potential to support healthy aging by reducing accumulation of senescent cells; promising preclinical data with limited human trials.
MyricetinCAS 529-44-23,3',4',5,5',7-HexahydroxyflavonePolyphenol (Flavonol)Goji BerryLycium barbarumDried FruitModerateStudied for antioxidant, anti-inflammatory, and potential neuroprotective properties; associated with healthy blood glucose management in preclinical models.
IsorhamnetinCAS 480-19-33'-Methoxy-3,4',5,7-tetrahydroxyflavone; Quercetin-3'-methyl etherPolyphenol (Flavonol)GinkgoGinkgo bilobaLeavesModerateA methylated quercetin metabolite studied for potential neuroprotective and anti-inflammatory properties; of interest in cardiovascular and cognitive health research.
MorinCAS 480-16-02',3,4',5,7-PentahydroxyflavonePolyphenol (Flavonol)GuavaPsidium guajavaFruitModerateStudied for antioxidant and potential neuroprotective effects; may support immune function and inhibit uric acid synthesis, with relevance to gout management research.
GalanginCAS 548-83-43,5,7-Trihydroxyflavone; Galangin flavonolPolyphenol (Flavonol)GalangalAlpinia officinarumRhizomeModerateStudied for antiviral, antibacterial, and anti-inflammatory properties; may modulate eicosanoid pathways relevant to the body's healthy inflammatory response.
RutinCAS 153-18-4Quercetin-3-rutinoside; Rutoside; Vitamin PPolyphenol (Flavonol Glycoside)BuckwheatFagopyrum esculentumAerial PartsModerateThe glycosylated form of quercetin; studied for capillary-strengthening and anti-oedematous properties. Used clinically in some countries for venous insufficiency support.
GossypetinCAS 489-35-08-Hydroxyquercetin; Hibiscus flavonolPolyphenol (Flavonol)HibiscusHibiscus sabdariffaCalyxModerateStudied for diuretic and antihypertensive properties; a distinctive 8-hydroxylated flavonol found in hibiscus calyx preparations.
QuercetagetinCAS 1169-23-96-Hydroxyquercetin; Marigold flavonolPolyphenol (Flavonol)MarigoldTagetes erectaFlower PetalsEmergingA hexahydroxylated flavonol studied for antiviral and antiproliferative properties in early-stage laboratory research.
PatuletinCAS 20229-30-56-Methoxyquercetin; Marigold flavonolPolyphenol (Flavonol)MarigoldTagetes patulaFlower PetalsEmergingStudied for anti-inflammatory and chondroprotective properties in early-stage research; may contribute to joint health maintenance.
SpinacetinCAS 28610-81-35,3'-Dihydroxy-3,4',7-trimethoxyflavonePolyphenol (Flavonol)SpinachSpinacia oleraceaLeavesEmergingA methylated flavonol found in spinach; studied for antioxidant activity in early-stage research.
Isorhamnetin-3-glucosideCAS 5041-82-7Isorhamnetin glucoside; NarcissinPolyphenol (Flavonol Glycoside)Sea BuckthornHippophae rhamnoidesBerriesModerateA bioavailable isorhamnetin glycoside studied for cardiovascular and anti-inflammatory properties in the context of sea buckthorn berry consumption.
LaricitrinCAS 16290-07-63,4',5,7-Tetrahydroxy-3'-methoxyflavonolPolyphenol (Flavonol)Red Wine GrapeVitis viniferaFruit SkinEmergingA minor grape skin flavonol studied for antioxidant and vascular health-supporting properties.
SyringetinCAS 528-53-03,4',5,7-Tetrahydroxy-3',5'-dimethoxyflavonolPolyphenol (Flavonol)Red Wine GrapeVitis viniferaFruit SkinEmergingA methylated flavonol found in grape skin; studied for potential contributions to cardiovascular antioxidant protection.
FLAVONES
ApigeninCAS 520-36-54',5,7-Trihydroxyflavone; Chamomile FlavonePolyphenol (Flavone)ParsleyPetroselinum crispumLeaf / StalkModerateStudied for mild anxiolytic, anti-inflammatory, and potential neuroprotective properties; may support healthy nervous system function and cellular autophagy.
LuteolinCAS 491-70-33',4',5,7-TetrahydroxyflavonePolyphenol (Flavone)CeleryApium graveolensLeaf / SeedModerateStudied for anti-inflammatory and potential neuroprotective properties; may contribute to mast cell stabilisation and support a healthy inflammatory balance.
DiosminCAS 520-27-4Diovenor; Detralex constituentPolyphenol (Flavone Glycoside)Sweet OrangeCitrus sinensisFruit PeelHighA clinically used phlebotonic flavonoid; well-supported by RCTs for venous insufficiency and haemorrhoidal symptom management, typically combined with hesperidin.
DiosmetinCAS 520-34-3Diosmin aglycone; 4'-Methyl-luteolinPolyphenol (Flavone)Lemon / CitrusCitrus limonFruit PeelModerateThe aglycone of diosmin; studied for venous tone support and anti-inflammatory properties relevant to circulatory health.
AcacetinCAS 480-44-44'-Methoxy-apigenin; Black Locust flavonePolyphenol (Flavone)Black LocustRobinia pseudoacaciaFlowersModerateStudied for antiarrhythmic and anti-inflammatory properties; may contribute to the stabilisation of cardiac electrical activity in preclinical models.
TangeretinCAS 481-53-84',5,6,7,8-Pentamethoxyflavone; Citrus flavonePolyphenol (Flavone)TangerineCitrus reticulataFruit PeelModerateA polymethoxylated flavone studied for neuroprotective and potential antiproliferative properties; may cross the blood-brain barrier more readily than less methylated flavones.
NobiletinCAS 478-01-33',4',5,6,7,8-HexamethoxyflavonePolyphenol (Flavone)TangerineCitrus reticulataFruit PeelModerateStudied for circadian rhythm modulation, hepatic lipid regulation, and potential neuroprotective properties; of interest in metabolic syndrome and dementia research.
SinensetinCAS 466-49-93',4',5,6,7-PentamethoxyflavonePolyphenol (Flavone)Sweet OrangeCitrus sinensisFruit PeelEmergingA polymethoxylated citrus flavone studied for anti-angiogenic and anti-inflammatory properties in early-stage laboratory research.
BaicaleinCAS 491-67-85,6,7-Trihydroxyflavone; Scutellaria aglyconePolyphenol (Flavone)Chinese SkullcapScutellaria baicalensisRootsModerateStudied for antiviral, anti-inflammatory, and potential neuroprotective properties; the aglycone of baicalin with higher membrane permeability.
BaicalinCAS 21967-41-9Baicalein-7-glucuronide; Scutellaria glycosidePolyphenol (Flavone Glycoside)Chinese SkullcapScutellaria baicalensisRootsModerateThe primary flavone of Scutellaria root; studied for anxiolytic, anti-inflammatory, and antiviral properties, with some human trial data available.
WogoninCAS 632-85-95,7-Dihydroxy-8-methoxyflavonePolyphenol (Flavone)Chinese SkullcapScutellaria baicalensisRootsModerateStudied for neuroprotective, anti-inflammatory, and potential anti-anxiety properties in preclinical models; complements baicalin in Scutellaria preparations.
ScutellareinCAS 529-53-36-Hydroxy-4',5,7-trihydroxyflavonePolyphenol (Flavone)Chinese SkullcapScutellaria baicalensisRootsEmergingStudied for potential antiviral and neuroprotective effects in early-stage research; a hydroxylated flavone that may contribute to Scutellaria's anti-infective properties.
HispidulinCAS 1447-88-74'-Methoxy-5,6,7-trihydroxyflavone; DinatinPolyphenol (Flavone)SageSalvia officinalisLeavesEmergingStudied for GABA-A receptor modulation with potential anticonvulsant properties in preclinical models; may support healthy nervous system calming.
EupatilinCAS 22368-21-45,7-Dihydroxy-3',4',6-trimethoxyflavonePolyphenol (Flavone)MugwortArtemisia asiaticaLeavesModerateA methylated flavone studied for gastroprotective properties; clinically investigated in South Korea for gastric mucosa protection and ulcer support.
VitexinCAS 3681-93-48-C-Glucosylapigenin; Hawthorn flavonePolyphenol (Flavone C-Glycoside)HawthornCrataegus spp.Fruit / LeafModerateStudied for cardioprotective, antihypertensive, and antispasmodic properties; contributes to the well-established cardiovascular benefit of hawthorn preparations.
IsovitexinCAS 38953-85-46-C-Glucosylapigenin; Passion Flower flavonePolyphenol (Flavone C-Glycoside)Passion FlowerPassiflora incarnataAerial PartsModerateStudied for anxiolytic and sedative-supportive properties; contributes to the evidence base for passionflower in sleep quality support.
OrientinCAS 28543-07-98-C-Glucosylluteolin; Rooibos flavonePolyphenol (Flavone C-Glycoside)RooibosAspalathus linearisLeavesModerateStudied for antioxidant, cardioprotective, and anti-inflammatory properties; a characteristic flavone of rooibos tea with good bioavailability data.
Iso-orientinCAS 4261-42-16-C-Glucosylluteolin; Barley grass flavonePolyphenol (Flavone C-Glycoside)Barley GrassHordeum vulgareYoung LeavesModerateStudied for antioxidant and hepatoprotective properties; contributes to the nutritional profile of barley grass preparations.
RhoifolinCAS 17306-46-6Apigenin-7-neohesperidosidePolyphenol (Flavone Glycoside)Sour OrangeCitrus aurantiumFruit PeelModerateStudied for cardioprotective and lipid-modulating properties; contributes to the overall flavonoid profile of bitter citrus preparations.
Vicenin-2CAS 4604-81-36,8-Di-C-glucosylapigenin; Tulsi flavonePolyphenol (Flavone C-Glycoside)Tulsi (Holy Basil)Ocimum sanctumLeavesModerateStudied for radioprotective and immunomodulatory properties in preclinical research; contributes to the adaptogenic profile of holy basil.
ChrysinCAS 480-40-05,7-Dihydroxyflavone; Bee Propolis flavonePolyphenol (Flavone)Bee PropolisPopulus spp.ResinModerateStudied for potential aromatase-inhibiting properties and mild anxiolytic effects; human bioavailability is poor without delivery enhancement.
GeraldoneCAS 480-44-43',5'-Dimethoxy-4'-hydroxyflavone; Red Clover flavonePolyphenol (Flavone)Red CloverTrifolium pratenseFlowersEmergingA minor flavone studied for oestrogenic and bone density-supporting properties in the context of red clover isoflavone research.
FLAVANONES
HesperidinCAS 520-26-3Hesperetin-7-rutinoside; Diosmin companionPolyphenol (Flavanone Glycoside)Sweet OrangeCitrus sinensisFruit PeelModerateStudied for venous tone support, capillary permeability reduction, and anti-inflammatory properties; used in combination with diosmin in clinically validated venous products.
NaringeninCAS 480-41-14',5,7-Trihydroxyflavanone; Citrus aglyconePolyphenol (Flavanone)GrapefruitCitrus paradisiFruit PeelModerateStudied for insulin-sensitising, hepatoprotective, and anti-inflammatory properties; may support healthy metabolic balance when consumed as part of a citrus-rich diet.
NaringinCAS 10236-47-2Naringenin-7-neohesperidosidePolyphenol (Flavanone Glycoside)GrapefruitCitrus paradisiFruit PeelModerateStudied for CYP3A4 inhibition that can significantly increase bioavailability of co-administered compounds; also studied for lipid-lowering and bone health-supporting properties.
HesperetinCAS 520-33-24'-Methoxy-eriodictyol; Hesperidin aglyconePolyphenol (Flavanone)LemonCitrus limonFruit PeelModerateThe bioactive aglycone of hesperidin; studied for vasotonic, anti-inflammatory, and potential neuroprotective effects with good intestinal permeability.
EriodictyolCAS 552-58-93',4',5,7-Tetrahydroxyflavanone; Yerba SantaPolyphenol (Flavanone)Yerba SantaEriodictyon californicumLeavesModerateStudied for mucolytic, anti-inflammatory, and flavour-modifying properties; investigated as a bitterness-masking agent in food and pharmaceutical formulations.
PoncirinCAS 14941-08-3Isosakuranetin-7-neohesperidosidePolyphenol (Flavanone Glycoside)Trifoliate OrangePoncirus trifoliataUnripe FruitModerateStudied for gastroprotective effects against ulceration and for apoptosis-inducing properties in cancer cell line research.
DidyminCAS 14259-45-1Isosakuranetin-7-rutinoside; Mandarin flavanonePolyphenol (Flavanone Glycoside)Mandarin OrangeCitrus reticulataFruit PeelEmergingStudied for neuroprotective properties and potential to stimulate nerve growth factor expression in preclinical models.
SakuranetinCAS 1486-69-75,4'-Dihydroxy-7-methoxyflavanone; Rice phytoalexinPolyphenol (Flavanone)Rice / Cherry TreeOryza sativaLeavesModerateA phytoalexin produced by rice in response to fungal infection; studied for antiallergic and anti-inflammatory properties in human cell models.
SterubinCAS 3145-22-4Eriodictyol-7-methyl etherPolyphenol (Flavanone)Yerba SantaEriodictyon californicumLeavesEmergingStudied in early-stage research for potential neuroprotective effects on ageing neurons; of interest in Alzheimer's disease pharmacological research.
BavachinCAS 20784-50-3Psoralea flavanone; Bakuchiol companionPolyphenol (Flavanone)PsoraleaPsoralea corylifoliaSeedsModerateStudied for osteogenic and anti-inflammatory properties; contributes to the bone health-supportive and immune-modulatory profile of Psoralea preparations.
LiquiritinCAS 551-15-5Licorice flavanone; Liquiritigenin glucosidePolyphenol (Flavanone Glycoside)Licorice RootGlycyrrhiza glabraRootsModerateStudied for gastroprotective and antidepressant-like properties; contributes to the well-established digestive-soothing benefits of licorice root preparations.
FLAVAN-3-OLS (CATECHINS & PROANTHOCYANIDINS)
CatechinCAS 154-23-4(+)-Catechin; Catechinic acidPolyphenol (Flavan-3-ol)Green TeaCamellia sinensisLeavesModerateA dietary flavan-3-ol studied for antioxidant and cardiovascular-supportive properties; may contribute to healthy vascular function and normal lipid profiles.
EpicatechinCAS 490-46-0(-)-Epicatechin; ECPolyphenol (Flavan-3-ol)Dark ChocolateTheobroma cacaoSeeds (Bean)ModerateStudied for vasodilatory, cardioprotective, and potential muscle function-supporting properties; associated with improved endothelial function in clinical trials at high cocoa intake.
EGCGCAS 989-51-5Epigallocatechin gallate; EGCg; Tea CatechinPolyphenol (Flavan-3-ol)Green TeaCamellia sinensisLeavesModerateThe most studied green tea catechin; may support metabolic health, immune function, and antioxidant defence. Human bioavailability is moderate and effect sizes vary across trials.
Epicatechin GallateCAS 1257-08-5ECG; (-)-Epicatechin-3-gallatePolyphenol (Flavan-3-ol)Green TeaCamellia sinensisLeavesModerateA green tea catechin gallate ester; studied for antimicrobial and antioxidant properties alongside EGCG in the context of green tea's overall health benefits.
GallocatechinCAS 3371-27-5(+)-Gallocatechin; GCPolyphenol (Flavan-3-ol)Green TeaCamellia sinensisLeavesModerateA flavan-3-ol present in green tea alongside EGCG; contributes to the cumulative antioxidant and anti-inflammatory activity of tea catechin mixtures.
Gallocatechin GallateCAS 4233-96-9GCG; (+)-Gallocatechin-3-gallatePolyphenol (Flavan-3-ol)Green TeaCamellia sinensisLeavesModerateStudied for lipid metabolism-modulating and immunomodulatory properties as part of the green tea catechin complex.
ProcyanidinsOPC; Oligomeric proanthocyanidins; PACPolyphenol (Proanthocyanidin)Grape Seed / AppleVitis vinifera / Malus domesticaSeeds / SkinModerateA class of condensed tannins studied extensively for cardiovascular, skin, and antioxidant support; grape seed extract OPCs have multiple human trials showing bioavailability and vascular benefits.
Procyanidin B2CAS 29106-49-8Epicatechin-(4b-8)-epicatechinPolyphenol (Proanthocyanidin)CocoaTheobroma cacaoSeedsModerateStudied for vasodilatory, skin elasticity-supporting, and antioxidant properties; one of the best-characterised proanthocyanidin dimers.
Procyanidin C1CAS 37064-30-5Epicatechin trimerPolyphenol (Proanthocyanidin)Grape SeedVitis viniferaSeedsEmergingStudied in early-stage research for potential senolytic properties; of interest in longevity and healthy aging research.
TheaflavinCAS 4670-05-7TF1; Black Tea polyphenolPolyphenol (Theaflavin)Black TeaCamellia sinensisFermented LeavesModerateThe characteristic orange-red pigment of black tea; studied for cholesterol-lowering and cardiovascular-supportive properties with promising clinical trial data.
ThearubiginsTR; Black Tea polymersPolyphenol (Theaflavin)Black TeaCamellia sinensisFermented LeavesModerateA complex mixture of oxidised catechin polymers accounting for most of black tea's colour and antioxidant capacity; studied for gut health and cardiovascular support.
FLAVANONOLS (DIHYDROFLAVONOLS)
TaxifolinCAS 480-18-2Dihydroquercetin; DHQ; Siberian Larch extractPolyphenol (Flavanonol)Siberian LarchLarix sibiricaWood / BarkModerateStudied for antioxidant, capillary-strengthening, and hepatoprotective properties; used in supplements for vascular and liver health with some human trial data.
AromadendrinCAS 480-20-6Dihydrokaempferol; Eucalyptus flavanonolPolyphenol (Flavanonol)EucalyptusEucalyptus globulusWood / LeavesModerateStudied for antioxidant and mild blood glucose-modulating properties; a biosynthetic intermediate in the flavonoid pathway.
AmpelopsinCAS 27200-12-0Dihydromyricetin; DHM; Vine TeaPolyphenol (Flavanonol)Vine TeaAmpelopsis grossedentataLeavesModerateStudied for hepatoprotective properties and support for alcohol metabolism; may accelerate ethanol clearance. Chinese clinical research available though quality is variable.
FLAVONOLIGNANS
SilybinCAS 22888-70-6Silibinin; Milk Thistle primary flavonolignanPolyphenol (Flavonolignan)Milk ThistleSilybum marianumSeedsHighThe primary bioactive of Milk Thistle (Silymarin complex); well-supported by clinical trials for hepatoprotective effects; may support liver cell membrane integrity against toxins.
SilychristinCAS 33889-69-9Silymarin component BPolyphenol (Flavonolignan)Milk ThistleSilybum marianumSeedsModerateA constituent of the silymarin complex studied for hepatoprotective and antioxidant effects; may contribute to liver tissue regeneration alongside silybin.
SilydianinCAS 29782-68-1Silymarin component CPolyphenol (Flavonolignan)Milk ThistleSilybum marianumSeedsModerateA minor silymarin component studied for stimulation of RNA polymerase I activity, which may support hepatocyte regeneration.
ISOFLAVONES & PHYTOESTROGENS
GenisteinCAS 446-72-05,7,4'-Trihydroxyisoflavone; Soy isoflavonePolyphenol (Isoflavone)SoybeanGlycine maxMature SeedModerateA phytoestrogenic isoflavone studied for potential benefits to bone density and menopausal symptoms; bioactivity is context-dependent and varies with individual gut microbiome composition.
DaidzeinCAS 486-66-87,4'-Dihydroxyisoflavone; Soy isoflavonePolyphenol (Isoflavone)SoybeanGlycine maxMature SeedModerateA phytoestrogenic isoflavone studied for cardiovascular and antioxidant properties; its conversion to equol in the gut is a key variable determining individual response.
Biochanin ACAS 491-80-54'-Methylgenistein; Red Clover isoflavonePolyphenol (Isoflavone)Red CloverTrifolium pratenseFlower HeadsModerateA methylated isoflavone that is demethylated to genistein in vivo; studied for hormonal balance support and potential contributions to muscle strength maintenance.
FormononetinCAS 485-72-37-Hydroxy-4'-methoxyisoflavone; Red CloverPolyphenol (Isoflavone)Red CloverTrifolium pratenseAerial PartsModerateA phytoestrogenic isoflavone studied for bone density support and female hormonal health; converted to daidzein and equol in the human gut.
GlyciteinCAS 40957-83-36-Methoxydaidzein; Soy minor isoflavonePolyphenol (Isoflavone)SoybeanGlycine maxMature SeedModerateA minor soy isoflavone studied for oestrogenic and antioxidant properties; contributes to the overall health profile of soy-based foods and isoflavone extracts.
DaidzinCAS 552-66-9Daidzein-7-glucoside; Soy isoflavone glycosidePolyphenol (Isoflavone Glycoside)Kudzu RootPueraria lobataRootsModerateStudied for potential to reduce alcohol craving and support cardiovascular health; the glucoside form of daidzein with distinct pharmacokinetic properties.
PuerarinCAS 3681-99-0Daidzein-8-C-glucoside; Kudzu root isoflavonePolyphenol (Isoflavone C-Glycoside)KudzuPueraria lobataRootsModerateStudied for cardiovascular benefits including improved cerebral blood flow and potential reduction of alcohol-seeking behaviour; used clinically in China.
CalycosinCAS 20575-57-93'-Hydroxyformononetin; Astragalus isoflavonePolyphenol (Isoflavone)AstragalusAstragalus membranaceusRootsModerateStudied for potential pro-angiogenic and oestrogen receptor-mediated effects; contributes to the cardiovascular and adaptogenic activity of Astragalus root.
IrisolidoneCAS 32752-26-4Pratensein; Pueraria isoflavonePolyphenol (Isoflavone)Kudzu / IrisPueraria lobataRootsEmergingA methylated isoflavone studied for antioxidant and potential immunomodulatory properties in early-stage research.
EquolCAS 531-95-3(S)-Equol; Gut microbiome metabolitePolyphenol (Isoflavandiol)Human MicrobiomeDerived from SoyIntestinal By-productModerateA gut bacterial metabolite of daidzein with higher oestrogenic potency than its parent; associated with more pronounced isoflavone health benefits in equol-producer individuals.
GlabridinCAS 59870-68-7Licorice isoflavan; Skin-brightening agentPolyphenol (Isoflavan)Licorice RootGlycyrrhiza glabraRootsModerateStudied for tyrosinase inhibition, UV protection, and anti-inflammatory properties; widely used in dermatological preparations for skin-brightening support.
PrunetinCAS 552-59-05-Methylgenistein; Plum isoflavonePolyphenol (Isoflavone)PlumPrunus domesticaWood / BarkEmergingA methylated isoflavone studied for anti-inflammatory and cardiovascular protective properties in early-stage research.
CoumestrolCAS 479-13-0Coumestan phytoestrogen; AlfalfaPolyphenol (Coumestan)AlfalfaMedicago sativaLeaves / SproutsModerateThe most potent plant coumestan phytoestrogen; studied for oestrogenic receptor activity relevant to bone density, menopausal health, and hormonal balance research.
WedelolactoneCAS 524-12-9Eclipta coumestan; Liver protectorPolyphenol (Coumestan)False DaisyEclipta prostrataAerial PartsModerateStudied for hepatoprotective, anti-venom, and anti-inflammatory properties; supports the traditional use of Eclipta in Ayurvedic medicine for liver health.
PsoralidinCAS 19879-32-4Psoralea coumestanPolyphenol (Coumestan)Scurfy PeaPsoralea corylifoliaSeedsEmergingStudied for antimicrobial and antiproliferative properties in early-stage laboratory research; contributes to the pharmacological activity of Psoralea seed preparations.
CHALCONES & DIHYDROCHALCONES
IsoliquiritigeninCAS 961-29-54,4',2'-Trihydroxychalcone; Licorice chalconePolyphenol (Chalcone)Licorice RootGlycyrrhiza glabraRootsModerateStudied for smooth muscle relaxant, anti-inflammatory, and potential oestrogenic properties; contributes to the digestive-soothing activity of licorice root.
ButeinCAS 487-52-53,4,2',4'-TetrahydroxychalconePolyphenol (Chalcone)ToxicodendronToxicodendron vernicifluumHeartwoodModerateStudied for potent anti-inflammatory and antioxidant properties; may support inhibition of NF-kB and STAT3 pathways relevant to chronic inflammation.
PhloretinCAS 60-82-22',4,4',6'-Tetrahydroxychalcone; Apple chalconePolyphenol (Dihydrochalcone)AppleMalus domesticaLeaves / BarkModerateStudied for antioxidant, anti-inflammatory, and potential insulin-sensitising properties; inhibits glucose transport across cell membranes in laboratory models.
PhloridzinCAS 60-81-1Phloretin-2'-glucoside; Apple bark glycosidePolyphenol (Dihydrochalcone)AppleMalus domesticaBark / Root BarkModerateStudied for SGLT inhibition and blood glucose-lowering effects; formed the conceptual basis for the SGLT2 inhibitor drug class used clinically in diabetes management.
AspalathinCAS 88597-18-6Rooibos dihydrochalcone; C-glucosidePolyphenol (Dihydrochalcone)RooibosAspalathus linearisLeavesModerateA unique South African plant polyphenol; studied for antidiabetic, cardioprotective, and oxidative stress-reducing properties with a moderate evidence base.
Naringenin ChalconeNaringenin open-form; Tomato chalconePolyphenol (Chalcone)TomatoSolanum lycopersicumSkinEmergingThe chalcone biosynthetic precursor of naringenin; studied for anti-inflammatory properties and found naturally in tomato skin.
PRENYLFLAVONOIDS
XanthohumolCAS 6754-58-1XN; Hops prenylflavonoidPolyphenol (Prenylflavonoid)HopsHumulus lupulusFemale InflorescenceModerateStudied for broad-spectrum anti-inflammatory, antioxidant, and potential cancer chemopreventive properties; the most abundant prenylflavonoid in hops.
IsoxanthohumolCAS 70553-76-3IXN; Hops prenylflavanonePolyphenol (Prenylflavonoid)HopsHumulus lupulusFemale InflorescenceModerateStudied as a mild phytoestrogen and for its conversion to the more potent 8-prenylnaringenin; contributes to the hormonal balance-supporting profile of hops.
8-PrenylnaringeninCAS 53846-50-78-PN; Hops potent phytoestrogenPolyphenol (Prenylflavonoid)HopsHumulus lupulusFemale InflorescenceModerateConsidered among the most potent plant phytoestrogens; studied for menopausal symptom management including hot flush relief. Limited but emerging clinical evidence.
ANTHOCYANINS & ANTHOCYANIDINS
CyanidinCAS 528-58-5Cyanidin chloride; Red-blue anthocyanidinPolyphenol (Anthocyanidin)BlackberryRubus fruticosusFruit SkinModerateStudied for vascular protection, antioxidant activity, and potential blood glucose-modulating properties; widely distributed in dark-coloured berries and fruits.
DelphinidinCAS 528-53-0Blue-purple anthocyanidinPolyphenol (Anthocyanidin)BlueberryVaccinium corymbosumFruit SkinModerateStudied for antioxidant, anti-inflammatory, and potential cardioprotective properties; associated with healthy cognitive aging in epidemiological research.
MalvidinCAS 643-84-5Red wine anthocyanidin; 3',5'-Dimethoxy-delphinidinPolyphenol (Anthocyanidin)Red Wine GrapeVitis viniferaFruit SkinModerateThe predominant anthocyanidin in red wine; studied for cardiovascular protection including arterial flexibility support and platelet aggregation modulation.
PeonidinCAS 134-01-03'-Methoxy-cyanidin; Cranberry anthocyanidinPolyphenol (Anthocyanidin)CranberryVaccinium oxycoccosFruit SkinModerateStudied for antioxidant and anti-inflammatory properties; contributes to the urinary tract health-supportive profile of cranberry alongside proanthocyanidins.
PelargonidinCAS 134-04-3Orange-red anthocyanidin; Strawberry pigmentPolyphenol (Anthocyanidin)StrawberryFragaria ananassaFruit SkinModerateA dietary anthocyanidin studied for anti-inflammatory and vascular health-supportive properties; the primary pigment of strawberries.
PetunidinCAS 1429-30-7Blue-purple anthocyanidin; Black CurrantPolyphenol (Anthocyanidin)Black CurrantRibes nigrumFruit SkinModerateStudied for antioxidant and anti-inflammatory properties; contributes to the cardiovascular and cognitive health support associated with dark berry consumption.
Cyanidin-3-glucosideCAS 7084-24-4C3G; Kuromanin; Berry anthocyaninPolyphenol (Anthocyanin)ElderberrySambucus nigraFruitModerateA highly bioavailable anthocyanin form; studied for antioxidant, anti-inflammatory, and potential antiviral properties with some human bioavailability data.
Cyanidin-3-rutinosideCAS 28338-59-2Keracyanin; Tart Cherry anthocyaninPolyphenol (Anthocyanin)Tart CherryPrunus cerasusFruit SkinModerateStudied for anti-inflammatory and muscle recovery support; human trials support its role in reducing exercise-induced muscle soreness.
Delphinidin-3-glucosideCAS 6906-38-3Myrtillin; Bilberry anthocyaninPolyphenol (Anthocyanin)BilberryVaccinium myrtillusFruit SkinModerateStudied for retinal protection and visual acuity support; bilberry anthocyanins have an established evidence base for eye health, particularly in low-light adaptation.
STILBENES
ResveratrolCAS 501-36-0Trans-resveratrol; 3,5,4'-TrihydroxystilbenePolyphenol (Stilbene)Red GrapesVitis viniferaFruit SkinModerateA polyphenolic stilbene studied for sirtuin activation, cardiovascular protection, and anti-aging properties; human bioavailability is limited and effect sizes in trials are modest.
PterostilbeneCAS 537-42-83,5-Dimethoxy-4'-hydroxystilbene; Blueberry stilbenePolyphenol (Stilbene)BlueberryVaccinium corymbosumFruitModerateA dimethylated resveratrol analog with significantly improved oral bioavailability; studied for cognitive support, antioxidant, and potential lipid-lowering properties.
PiceatannolCAS 10083-24-63,3',4,5'-Tetrahydroxystilbene; Passion Fruit stilbenePolyphenol (Stilbene)Passion FruitPassiflora edulisSeedsModerateA hydroxylated resveratrol metabolite with higher potency; studied for anti-inflammatory, antiproliferative, and potential skin health-supporting properties.
PinostilbeneCAS 22139-77-13,4'-Dihydroxy-5-methoxystilbenePolyphenol (Stilbene)Siberian PinePinus sibiricaBarkEmergingA monomethylated resveratrol analog studied for antioxidant and anti-inflammatory properties in early-stage research.
RhaponticinCAS 155-58-8Rhapontin; Rhubarb stilbene glucosidePolyphenol (Stilbene Glycoside)RhubarbRheum rhabarbarumRhizomeModerateA stilbene glycoside studied for oestrogenic receptor binding and potential support for menopausal symptoms; contributes to the phytoestrogenic activity of rhubarb root.
PHENOLIC ACIDS — HYDROXYCINNAMIC
Chlorogenic AcidCAS 327-97-93-Caffeoylquinic acid; CGA; Green CoffeePolyphenol (Hydroxycinnamic Acid)Green CoffeeCoffea arabicaDried SeedModerateStudied for blood glucose-modulating properties by slowing carbohydrate absorption; well-documented antioxidant with moderate human trial evidence.
Caffeic AcidCAS 331-39-53,4-Dihydroxycinnamic acidPolyphenol (Hydroxycinnamic Acid)CoffeeCoffea arabicaSeed (Bean)ModerateStudied for antioxidant and anti-inflammatory properties; may help inhibit formation of advanced glycation end-products relevant to metabolic health.
Rosmarinic AcidCAS 20283-92-5alpha-O-Caffeoyl-3,4-dihydroxyphenyllactic acidPolyphenol (Hydroxycinnamic Acid)RosemarySalvia rosmarinusLeaf TissueModerateStudied for antioxidant, anti-inflammatory, and potential anxiolytic properties; supports the traditional use of rosemary and lemon balm for cognitive and mood wellbeing.
Ferulic AcidCAS 1135-24-63-Methoxy-4-hydroxycinnamic acid; FAPolyphenol (Hydroxycinnamic Acid)Whole WheatTriticum aestivumCereal BranModerateStudied for neuroprotective, antioxidant, and skin-photoprotective properties; may support healthy endothelial function and contribute to the value of whole grain consumption.
Sinapic AcidCAS 530-59-63,5-Dimethoxy-4-hydroxycinnamic acidPolyphenol (Hydroxycinnamic Acid)Mustard GreensBrassica junceaLeavesModerateStudied for antioxidant and anti-inflammatory properties; may support neuroprotection and serve as a skin UV-filter in topical applications.
p-Coumaric AcidCAS 501-98-44-Hydroxycinnamic acid; Para-coumaric acidPolyphenol (Hydroxycinnamic Acid)PeanutsArachis hypogaeaSeedsModerateStudied for antioxidant and potential anti-atherosclerotic properties; may help maintain healthy lipid profiles when consumed as part of a plant-rich diet.
Cinnamic AcidCAS 140-10-3(E)-3-Phenylacrylic acid; Trans-cinnamic acidPolyphenol (Hydroxycinnamic Acid)CinnamonCinnamomum cassiaBarkModerateStudied for antimicrobial and antioxidant properties; a primary aromatic constituent of cinnamon with mild anti-inflammatory activity.
Chicoric AcidCAS 70831-56-0Cichoric acid; Echinacea phenolicPolyphenol (Hydroxycinnamic Acid)EchinaceaEchinacea purpureaRoots / LeavesModerateStudied for immunomodulatory effects including enhancement of phagocytic activity; contributes to the immune-supportive evidence base of Echinacea preparations.
Caftaric AcidCAS 67879-58-7Caffeoyl tartaric acid; Grapevine phenolicPolyphenol (Hydroxycinnamic Acid)GrapevineVitis viniferaFruit / JuiceModerateA hydroxycinnamic acid ester found in grapes and wine; studied for antioxidant and potential antiviral properties.
PHENOLIC ACIDS — HYDROXYBENZOIC
Gallic AcidCAS 149-91-73,4,5-Trihydroxybenzoic acidPolyphenol (Hydroxybenzoic Acid)Tea PlantCamellia sinensisLeavesModerateStudied for antioxidant, antimicrobial, and hepatoprotective properties; a key building block of hydrolysable tannins and an important dietary antioxidant.
Ellagic AcidCAS 476-66-4Benzoaric acid; Pomegranate polyphenolPolyphenol (Hydroxybenzoic Acid)PomegranatePunica granatumFruit / Seed HuskModerateStudied for antiproliferative and antioxidant properties; released from ellagitannins in the gut and studied for potential support of healthy cell cycle regulation.
Protocatechuic AcidCAS 99-50-33,4-Dihydroxybenzoic acid; PCAPolyphenol (Hydroxybenzoic Acid)AcaiEuterpe oleraceaFruit PulpModerateStudied for antioxidant, anti-inflammatory, and potential cardioprotective properties; a metabolite of anthocyanins and cyanidin compounds in the gut.
Gentisic AcidCAS 490-79-92,5-Dihydroxybenzoic acidPolyphenol (Hydroxybenzoic Acid)GentianGentiana luteaRootsModerateStudied for anti-inflammatory and hepatoprotective properties; a salicylate-related compound with antioxidant activity.
Syringic AcidCAS 530-57-44-Hydroxy-3,5-dimethoxybenzoic acidPolyphenol (Hydroxybenzoic Acid)DatesPhoenix dactyliferaFruitModerateStudied for antioxidant and neuroprotective properties; a methylated hydroxybenzoic acid with good bioavailability from dietary sources.
Vanillic AcidCAS 121-34-64-Hydroxy-3-methoxybenzoic acidPolyphenol (Hydroxybenzoic Acid)Vanilla BeanVanilla planifoliaSeed PodModerateStudied for antioxidant and anti-inflammatory properties; contributes to the health-relevant phenolic profile of vanilla and numerous plant foods.
3-O-Methylgallic AcidCAS 3149-27-73-O-MGA; Methylated gallic acidPolyphenol (Hydroxybenzoic Acid)EucalyptusEucalyptus spp.LeavesEmergingStudied for antioxidant and antimicrobial properties in early-stage research; a methylated gallic acid derivative found in various plant species.
ELLAGITANNINS & GALLOTANNINS
PunicalaginCAS 65995-63-3Alpha/Beta-Punicalagin; Pomegranate tanninPolyphenol (Ellagitannin)PomegranatePunica granatumFruit PeelModerateThe most abundant ellagitannin in pomegranate; studied for potent antioxidant, anti-inflammatory, and cardiovascular-supportive properties. One of the richest known dietary antioxidants.
CasuarictinCAS 79786-13-3Strawberry ellagitanninPolyphenol (Ellagitannin)StrawberryFragaria ananassaFruitModerateAn ellagitannin found in strawberries and raspberries; studied for antioxidant and potential antiproliferative properties in the context of berry consumption.
Sanguiin H-6CAS 82168-16-3Red Raspberry ellagitanninPolyphenol (Ellagitannin)Red RaspberryRubus idaeusFruitModerateA major ellagitannin in raspberries; studied for antioxidant and gut health-supportive properties following hydrolysis to ellagic acid in the gut.
CastalaginCAS 18046-00-9Chestnut wood ellagitanninPolyphenol (Ellagitannin)ChestnutCastanea sativaWood / HuskModerateStudied for antioxidant, antimicrobial, and blood glucose-modulating properties; found in oak and chestnut wood used in barrel-aged foods.
VescalaginCAS 20229-29-4Oak wood ellagitanninPolyphenol (Ellagitannin)Oak WoodQuercus spp.Wood TissueModerateStudied for anti-inflammatory and cardioprotective properties; imparted to wine, spirits, and foods from oak barrel contact.
GeraniinCAS 60976-49-0Cranesbill ellagitanninPolyphenol (Ellagitannin)CranesbillGeranium spp.Aerial PartsModerateStudied for antihypertensive, antiviral, and immunomodulatory properties; the characteristic ellagitannin of Geranium species used in traditional medicine.
CorilaginCAS 23094-69-1Phyllanthus ellagitannin; Hepatoprotective tanninPolyphenol (Ellagitannin)PhyllanthusPhyllanthus emblicaFruitModerateStudied for hepatoprotective and antiviral properties; contributes to the liver health benefits associated with Phyllanthus emblica (Amla) preparations.
PedunculaginCAS 41743-41-3Walnut ellagitanninPolyphenol (Ellagitannin)WalnutJuglans regiaPellicle (Skin)EmergingA walnut ellagitannin studied for antioxidant and cardiovascular-supportive properties; contributes to the polyphenol profile of whole walnuts.
GalloylglucoseCAS 14937-32-7Pentagalloylglucose; GallotanninPolyphenol (Gallotannin)RhubarbRheum rhabarbarumStalk / RootModerateA gallotannin studied for antioxidant and digestive health-supporting properties; also studied for potential anti-inflammatory and anti-adipogenic effects.
LIGNANS
SecoisolariciresinolCAS 80956-06-5SECO; Flaxseed lignan precursorPolyphenol (Lignan)FlaxseedLinum usitatissimumSeed CoatModerateA plant lignan converted by gut bacteria to the phytoestrogenic enterolignans enterodiol and enterolactone; studied for hormonal health and potential breast cancer risk modulation.
MatairesinolCAS 580-72-3Sesame lignan precursorPolyphenol (Lignan)Sesame SeedSesamum indicumSeed HuskModerateA dietary lignan that is converted to enterolactone by gut microbiota; may contribute to cardiovascular and hormonal health benefits associated with sesame consumption.
SesaminCAS 607-80-7Sesame primary lignanPolyphenol (Lignan)Sesame SeedSesamum indicumSeedsModerateThe primary lignan of sesame; studied for hepatoprotective, cholesterol-modulating, and antioxidant properties. May support healthy lipid metabolism.
PinoresinolCAS 6216-81-5Olive oil lignanPolyphenol (Lignan)Olive OilOlea europaeaFruit OilModerateStudied for antioxidant, blood glucose-modulating, and anti-inflammatory properties; contributes to the cardiovascular benefits associated with extra virgin olive oil consumption.
LariciresinolCAS 39459-36-6Broccoli lignan; Dietary lignanPolyphenol (Lignan)BroccoliBrassica oleraceaStemsModerateA dietary lignan studied for cardiovascular health support and phytoestrogenic activity; converted by gut microbiota to enterodiol.
SyringaresinolCAS 6216-81-5Grain lignan; Phytoestrogenic lignanPolyphenol (Lignan)Whole GrainsTriticum aestivumBranModerateA grain lignan studied for oestrogen receptor-binding activity and potential cardiovascular-protective effects as part of whole grain consumption.
MedioresinolCAS 14137-93-8Lemon lignan; Secoisolariciresinol relatedPolyphenol (Lignan)LemonCitrus limonFruit JuiceEmergingA minor dietary lignan studied for antioxidant properties; contributes to the overall lignan intake associated with citrus consumption.
HonokiolCAS 35354-74-6Magnolia lignan; Anxiolytic lignanPolyphenol (Lignan)MagnoliaMagnolia officinalisBarkModerateA bioactive neolignan studied for anxiolytic, anti-inflammatory, and potential neuroprotective properties; may modulate GABA-A receptors with good CNS penetration.
MagnololCAS 528-43-8Magnolia bark lignanPolyphenol (Lignan)MagnoliaMagnolia officinalisBarkModerateStudied for CNS-calming, anti-neuroinflammatory, and antioxidant properties; used alongside honokiol in traditional Chinese medicine preparations for anxiety and sleep support.
SchisandrinCAS 7432-28-2Schisandrin A; Wuweizisu APolyphenol (Lignan)SchisandraSchisandra chinensisBerriesModerateThe primary dibenzocyclooctadiene lignan of Schisandra; studied for hepatoprotective, adaptogenic, and cognitive-supporting properties with a moderate evidence base.
ArctigeninCAS 7770-78-7Burdock aglycone lignanPolyphenol (Lignan)BurdockArctium lappaSeedsModerateStudied for thermogenic, antiviral, and anti-inflammatory properties; may contribute to the traditional use of burdock for metabolic and immune support.
MacelignanCAS 68247-50-7Nutmeg lignan; Methylenedioxyphenyl lignanPolyphenol (Lignan)NutmegMyristica fragransSeedsModerateStudied for UV photoprotective and prostaglandin synthesis-inhibiting properties; contributes to the skin health-relevant profile of nutmeg preparations.
PHENYLETHANOIDS & SECOIRIDOIDS
HydroxytyrosolCAS 10597-60-13,4-DHPEA; Olive polyphenolPolyphenol (Phenylethanoid)OliveOlea europaeaFruit JuiceHighA highly bioavailable olive polyphenol with one of the highest recorded antioxidant activities among dietary compounds; associated with cardiovascular protection. Carries an EU health claim for LDL oxidation protection.
OleuropeinCAS 32619-42-4Olive leaf phenolic; Bitter glucosidePolyphenol (Secoiridoid)Olive LeafOlea europaeaLeaf TissueModerateThe dominant phenolic of olive leaf; studied for antihypertensive, antioxidant, and antimicrobial properties with an established traditional and emerging clinical evidence base.
OleocanthalCAS 289030-99-5p-HPEA-EDA; EVOO phenolic aldehydePolyphenol (Phenylethanoid)Extra Virgin Olive OilOlea europaeaFruit OilModerateStudied for COX-1 and COX-2 inhibitory activity analogous to ibuprofen; the compound responsible for the peppery throat sensation of high-quality extra virgin olive oil.
RosavinCAS 84954-92-7Rosavins; Rhodiola phenylpropanoidPolyphenol (Phenylpropanoid)RhodiolaRhodiola roseaRootsModerateOne of the marker compounds of Rhodiola rosea; studied for adaptogenic properties including cortisol modulation and enhancement of physical and mental endurance.
SalidrosideCAS 10338-51-9Rhodioloside; Rhodiola tyrosol glucosidePolyphenol (Phenylethanoid Glycoside)RhodiolaRhodiola roseaRootsModerateThe primary bioactive of Rhodiola rosea; studied for adaptogenic, neuroprotective, and antifatigue properties with a growing human clinical evidence base.
VerbascosideCAS 61276-17-3Acteoside; Mullein phenylethanoidPolyphenol (Phenylethanoid)MulleinVerbascum thapsusLeavesModerateA widely distributed phenylethanoid glycoside studied for antioxidant, anti-inflammatory, and potential neuroprotective properties; found in numerous medicinal plants.
EchinacosideCAS 82854-37-3Cistanche phenylethanoid; NeuroprotectivePolyphenol (Phenylethanoid)Desert HyacinthCistanche tubulosaStemModerateA phenylethanoid glycoside studied for neuroprotective, neurotrophic, and cognitive-supporting properties; used in traditional Chinese and Ayurvedic medicine for longevity support.
ActeosideCAS 61276-17-3Verbascoside; Phenylethanoid glycosidePolyphenol (Phenylethanoid)Forsythia / OliveForsythia suspensaLeavesModerateA widely found phenylethanoid studied for hepatoprotective, antiviral, and anti-inflammatory properties across multiple traditional medicine systems.
CURCUMINOIDS & MISCELLANEOUS POLYPHENOLS
CurcuminCAS 458-37-7Diferuloylmethane; Turmeric Yellow; E100Polyphenol (Curcuminoid)TurmericCurcuma longaRhizomeModerateA polyphenolic diarylheptanoid studied extensively for anti-inflammatory and antioxidant properties; poor oral bioavailability without formulation enhancement limits effects from standard preparations.
BisdemethoxycurcuminCAS 33171-16-3Curcumin III; Turmeric curcuminoidPolyphenol (Curcuminoid)TurmericCurcuma longaRhizomeModerateA minor curcuminoid studied for antioxidant and anti-inflammatory properties comparable to curcumin; part of the standardised curcumin extract complex.
DemethoxycurcuminCAS 22608-11-3Curcumin II; Turmeric curcuminoidPolyphenol (Curcuminoid)TurmericCurcuma longaRhizomeModerateAn intermediate curcuminoid studied for anti-inflammatory properties; contributes to the biological activity of standardised curcumin preparations.
Oleuropein AglyconeElenolic acid derivative; OAPolyphenol (Secoiridoid)OliveOlea europaeaFruit / LeafModerateThe more bioavailable aglycone form of oleuropein; studied for potent antioxidant, antihypertensive, and potential anti-amyloid properties.
LigustilideCAS 4431-01-0Sichuan Lovage phthalide; LIGPolyphenol (Phthalide)LigusticumLigusticum chuanxiongRhizomeModerateA phthalide studied for smooth muscle-relaxing, vasodilatory, and neuroprotective properties; the primary active compound of Chuanxiong herb.
HEMITERPENES
IsopreneCAS 78-79-52-Methyl-1,3-butadiene; Foliage volatileTerpenoid (Hemiterpene)AspenPopulus tremuloidesLeavesEmergingThe simplest biological terpene; released by plants under heat stress. Studied for its role in atmospheric chemistry and plant stress signalling.
Angelic AcidCAS 565-63-9(Z)-2-Methylbut-2-enoic acid; Angelica acidTerpenoid (Hemiterpene)Garden AngelicaAngelica archangelicaRootsModerateStudied for sedative and antispasmodic properties; contributes to the calming activity of Angelica root preparations used traditionally.
Tiglic AcidCAS 80-59-1(E)-2-Methylbut-2-enoic acid; Croton acidTerpenoid (Hemiterpene)CrotonCroton tigliumSeed OilEmergingA minor monoterpenoid acid studied for metabolic signalling activity; present in various plant essential oils and examined for anti-inflammatory potential.
Isovaleric AcidCAS 503-74-23-Methylbutanoic acid; Valerian acidTerpenoid (Hemiterpene)ValerianValeriana officinalisRhizomesModerateStudied for GABAergic activity contributing to the sedative and anxiolytic properties of valerian root preparations; also a minor fermentation metabolite.
MONOTERPENES
LimoneneCAS 5989-27-5D-Limonene; (+)-Limonene; Citrus terpeneTerpenoid (Monoterpene)Lemon / OrangeCitrus limon / sinensisFruit Peel OilModerateStudied for potential chemopreventive and digestive health-supporting properties; widely used in food, fragrance, and wellness applications. Emerging human trial data available.
Alpha-PineneCAS 80-56-8alpha-Pinene; Pine resin monoterpeneTerpenoid (Monoterpene)Pine TreePinus sylvestrisResin / BarkModerateThe most abundant monoterpene in nature; studied for bronchodilatory, anti-inflammatory, and potential memory-supporting properties via acetylcholinesterase inhibition.
Beta-PineneCAS 127-91-3beta-Pinene; Piney monoterpeneTerpenoid (Monoterpene)Rosemary / PineSalvia rosmarinusLeaves / ResinModerateStudied for antimicrobial and antifungal properties; contributes to the respiratory-supportive and antiseptic activity of pine and rosemary preparations.
LinaloolCAS 78-70-63,7-Dimethyl-1,6-octadien-3-ol; Lavender terpeneTerpenoid (Monoterpene)LavenderLavandula angustifoliaFlowersModerateStudied for anxiolytic and sedative-supportive properties via modulation of GABA-A receptors; a key aromatic component of lavender with some human trial evidence for stress reduction.
MentholCAS 89-78-1L-Menthol; Peppermint terpene alcoholTerpenoid (Monoterpene)PeppermintMentha x piperitaLeavesHighA TRPM8 receptor agonist used clinically as a topical analgesic and counterirritant; well-established for sore throat relief, nasal decongestion, and IBS symptom support.
CamphorCAS 76-22-2(+)-Camphor; Bornone; Camphor tree terpeneTerpenoid (Monoterpene)Camphor TreeCinnamomum camphoraBark / WoodHighA clinically used topical analgesic and mild counterirritant; incorporated in numerous licensed topical preparations for musculoskeletal discomfort and nasal decongestion.
ThymolCAS 89-83-82-Isopropyl-5-methylphenol; Thyme phenolTerpenoid (Monoterpene)ThymeThymus vulgarisLeavesHighA potent antimicrobial monoterpene with established activity against oral bacteria; used in licensed dental antiseptic preparations and studied for respiratory health support.
CarvacrolCAS 499-75-22-Methyl-5-(1-methylethyl)phenol; Oregano phenolTerpenoid (Monoterpene)OreganoOriganum vulgareLeavesModerateStudied for antimicrobial, anti-inflammatory, and gut health-supporting properties; may help maintain a healthy gut microbial balance and support mucosal integrity.
GeraniolCAS 106-24-1(E)-3,7-Dimethyl-2,6-octadien-1-ol; Rose terpeneTerpenoid (Monoterpene)Geranium / RosePelargonium graveolensFlowersModerateStudied for antimicrobial, antioxidant, and potential antiproliferative properties; widely used in aromatherapy and personal care formulations for its floral fragrance.
EucalyptolCAS 470-82-61,8-Cineole; Cineole; Eucalyptus terpeneTerpenoid (Monoterpene)EucalyptusEucalyptus globulusLeavesHighA clinically studied mucolytic and bronchosecretolytic agent; incorporated in licensed respiratory preparations for cough and bronchitis support. Evidence from multiple human trials.
Terpinen-4-olCAS 562-74-3Tea Tree primary component; p-Menth-1-en-4-olTerpenoid (Monoterpene)Tea TreeMelaleuca alternifoliaLeavesHighThe primary antimicrobial constituent of tea tree oil; well-supported clinically for topical bacterial and fungal skin infections, acne, and wound care.
HinokitiolCAS 499-44-5beta-Thujaplicin; Cypress terpeneTerpenoid (Monoterpene)CypressChamaecyparis obtusaHeartwoodModerateStudied for broad-spectrum antimicrobial and antifungal properties; used in oral hygiene and skincare formulations. Chelates iron to deprive bacteria of a key growth nutrient.
SabineneCAS 3387-41-5Sabinene; Black pepper monoterpeneTerpenoid (Monoterpene)Black PepperPiper nigrumDried FruitsEmergingA bicyclic monoterpene contributing to the spicy aroma of pepper and several essential oils; studied for antioxidant properties in early-stage research.
ThujoneCAS 546-80-5alpha-Thujone; Wormwood terpeneTerpenoid (Monoterpene)WormwoodArtemisia absinthiumAerial PartsModerateA GABA-A receptor modulator associated with the historical effects of absinthe; toxic at high doses. Subject to regulatory limits in food and beverages.
MyrceneCAS 123-35-3beta-Myrcene; Hops / Lemongrass terpeneTerpenoid (Monoterpene)Hops / LemongrassHumulus lupulusFlowers / LeavesModerateStudied for sedative and muscle relaxant properties; may enhance cellular permeability to aid absorption of co-administered compounds.
TerpineolCAS 98-55-5alpha-Terpineol; Pine terpene alcoholTerpenoid (Monoterpene)Lilac / PineSyringa vulgarisFlowers / SapModerateStudied for antimicrobial, anxiolytic, and anti-inflammatory properties; used in aromatherapy and studied for nervous system calming effects in animal models.
CitronellolCAS 106-22-9(R)-(-)-Citronellol; Citronella monoterpeneTerpenoid (Monoterpene)Citronella / RoseCymbopogon nardusLeavesModerateStudied for insect-repellent, antispasmodic, and antimicrobial properties; a primary component of commercial natural mosquito repellent preparations.
Perillyl AlcoholCAS 536-59-4p-Menth-1-en-7-ol; Lavender terpene alcoholTerpenoid (Monoterpene)LavenderLavandula angustifoliaFlowersModerateStudied for potential chemopreventive properties via Ras pathway modulation; clinical trials have been conducted for several cancer types though results are mixed.
MenthoneCAS 14073-97-3L-Menthone; Peppermint terpene ketoneTerpenoid (Monoterpene)PeppermintMentha x piperitaLeavesModerateA ketone monoterpene studied for antimicrobial and digestive comfort-supporting properties; contributes to the overall pharmacological activity of peppermint oil.
BorneolCAS 507-70-0Endo-borneol; Camphor reduction productTerpenoid (Monoterpene)Borneol CamphorDryobalanops aromaticaResinModerateStudied for neurological effects including CNS-penetrating anti-inflammatory properties; used in traditional Chinese medicine to enhance drug delivery to the brain.
NerolidolCAS 40716-66-3(E)-Nerolidol; Lemon grass sesquiterpeneTerpenoid (Sesquiterpene)LemongrassCymbopogon citratusLeavesModerateStudied for antimicrobial, anti-inflammatory, and potential skin-penetration-enhancing properties; of interest for topical drug delivery research.
IRIDOIDS (MONOTERPENE GLYCOSIDES)
AucubinCAS 479-98-1Aucuboside; Plantain iridoidTerpenoid (Iridoid)PlantainPlantago majorLeavesModerateStudied for hepatoprotective, anti-inflammatory, and antiallergic properties; may support liver cell protection and contribute to a healthy inflammatory response.
CatalpolCAS 2415-24-9Rehmannia iridoid; NeuroprotectiveTerpenoid (Iridoid)RehmanniaRehmannia glutinosaRootsModerateStudied for neuroprotective properties including protection of dopaminergic and cholinergic neurons; contributes to the cognitive health-supportive use of Rehmannia root.
GeniposideCAS 24512-63-8Gardenia iridoid glycosideTerpenoid (Iridoid)GardeniaGardenia jasminoidesFruitModerateStudied for antidiabetic, analgesic, and hepatoprotective properties; contributes to the blood sugar-modulating and liver-protective traditional uses of Gardenia.
LoganinCAS 18524-94-2Strychnos iridoid; MIA precursorTerpenoid (Iridoid)Strychnine TreeStrychnos nux-vomicaSeedsModerateA biosynthetic precursor to monoterpenoid indole alkaloids in plants; studied for neuroprotective and antidiabetic properties in early-stage research.
HarpagosideCAS 19716-97-7Devil's Claw primary iridoidTerpenoid (Iridoid)Devil's ClawHarpagophytum procumbensTubersHighThe primary bioactive of Devil's Claw; well-supported by clinical trials for osteoarthritis and chronic low back pain management. European regulatory recognition for joint health.
SwertiamarinCAS 17388-39-5Gentian bitter iridoidTerpenoid (Iridoid)GentianGentiana luteaRootsModerateA secoiridoid glycoside that stimulates gastric acid and bile secretion; supports the traditional use of gentian root as a digestive bitter and hepatoprotective agent.
NepetalactoneCAS 490-52-8Catnip iridoid; Feline attractantTerpenoid (Iridoid)CatnipNepeta catariaLeavesModerateStudied for insect-repellent properties; more effective than DEET against certain mosquito species in some laboratory studies. Also causes the characteristic behavioural response in domestic cats.
SESQUITERPENES
ArtemisininCAS 63968-64-9QHS; Qinghaosu; ArtemisininTerpenoid (Sesquiterpene Lactone)Sweet WormwoodArtemisia annuaLeaves / SeedsHighA Nobel Prize-recognised antimalarial; its endoperoxide bridge is activated by haem iron in Plasmodium parasites to produce toxic radical species. Forms the basis for WHO-recommended artemisinin combination therapies.
Beta-CaryophylleneCAS 87-44-5(E)-BCP; CB2 agonist terpeneTerpenoid (Sesquiterpene)Black Pepper / ClovePiper nigrumFruit / BudModerateA dietary CB2 receptor agonist studied for anti-inflammatory and analgesic properties without psychoactive effects; the first dietary compound identified as a cannabinoid receptor ligand.
Alpha-HumuleneCAS 6753-98-6alpha-Caryophyllene; Hops sesquiterpeneTerpenoid (Sesquiterpene)Hops / SageHumulus lupulusFlowersModerateStudied for anti-inflammatory and potential appetite-suppressing properties; contributes to the anti-inflammatory profile of hops alongside beta-caryophyllene.
FarnesolCAS 4602-84-0(E,E)-Farnesol; Floral sesquiterpeneTerpenoid (Sesquiterpene)Rose / CitronellaRosa damascenaFlowersModerateStudied for antimicrobial, antifungal, and potential antiproliferative properties; also acts as a quorum sensing inhibitor in bacterial biofilms.
BisabololCAS 23089-26-1(-)-alpha-Bisabolol; Chamomile sesquiterpeneTerpenoid (Sesquiterpene)ChamomileMatricaria chamomillaFlowersModerateStudied for skin-soothing, anti-inflammatory, and wound-healing properties; widely used in cosmetic preparations for sensitive and irritated skin.
ParthenolideCAS 20554-84-1Feverfew sesquiterpene lactoneTerpenoid (Sesquiterpene Lactone)FeverfewTanacetum partheniumLeavesModerateStudied for NF-kB inhibition, anti-migraine, and potential leukaemia stem cell-targeting properties; the primary bioactive of feverfew with moderate clinical evidence for migraine prevention.
HelenalinCAS 6754-13-8Arnica sesquiterpene lactoneTerpenoid (Sesquiterpene Lactone)ArnicaArnica montanaFlowersModerateA potent anti-inflammatory sesquiterpene lactone; supports the topical use of arnica for bruising, muscle soreness, and minor injury management. Toxic if taken internally.
CynaropicrinCAS 35688-04-1Artichoke bitter sesquiterpeneTerpenoid (Sesquiterpene Lactone)ArtichokeCynara scolymusLeavesModerateStudied for hepatoprotective, choleretic, and lipid-modulating properties; contributes to the liver and digestive health benefits of artichoke leaf extracts.
ThapsigarginCAS 67526-95-8SERCA pump inhibitor; Deadly CarrotTerpenoid (Sesquiterpene Lactone)Deadly CarrotThapsia garganicaRootsEmergingA potent SERCA pump inhibitor studied in oncological research; forms the basis for targeted drug delivery conjugates in prostate cancer research. Not for unsupervised use — toxic at very low doses.
GossypolCAS 303-45-7Cotton sesquiterpene aldehyde; Male contraceptiveTerpenoid (Sesquiterpene)CottonGossypium hirsutumSeeds / RootsModerateA dimeric sesquiterpene studied for male contraceptive and antiproliferative properties; associated with infertility-inducing effects in clinical research. Subject to significant safety concerns.
ValtrateCAS 18296-44-1Valerian IVHD-valtrate; Iridoid esterTerpenoid (Sesquiterpene)ValerianValeriana officinalisRootsModerateStudied for sedative and anxiolytic-supportive properties via GABAergic modulation; contributes to the sleep quality-supporting evidence base of valerian root preparations.
ChamazuleneCAS 529-05-5Blue Chamomile azuleneTerpenoid (Sesquiterpene)German ChamomileMatricaria chamomillaDistilled OilModerateFormed during steam distillation of chamomile; the compound responsible for the characteristic blue colour of the essential oil. Studied for anti-inflammatory and antiallergic properties.
CostunolideCAS 553-21-9Costus sesquiterpene lactoneTerpenoid (Sesquiterpene Lactone)CostusSaussurea costusRootsModerateStudied for anti-inflammatory, anti-angiogenic, and antiproliferative properties in preclinical cancer research; contributes to the traditional anti-inflammatory uses of Costus root.
SantoninCAS 481-06-1Levant Wormseed anthelminthicTerpenoid (Sesquiterpene Lactone)Levant WormseedArtemisia cinaFlower BudsHighA clinically established anthelminthic historically used to paralyse and expel intestinal roundworms; now largely superseded by modern anthelmintics due to toxicity concerns at effective doses.
ZingibereneCAS 495-60-3Ginger sesquiterpene; BisabolaneTerpenoid (Sesquiterpene)GingerZingiber officinaleRhizomeModerateA primary sesquiterpene of ginger; studied for antiemetic and gastrointestinal-soothing properties, contributing to the well-documented benefit of ginger for nausea management.
CurzereneCAS 6902-72-3Myrrh sesquiterpene; GermacranolideTerpenoid (Sesquiterpene)MyrrhCommiphora myrrhaResinModerateStudied for analgesic and anti-inflammatory properties; may interact with opioid receptors to contribute to pain relief. Part of the complex pharmacology of myrrh resin.
AlantolactoneCAS 546-43-0Elecampane sesquiterpene; HeleninTerpenoid (Sesquiterpene Lactone)ElecampaneInula heleniumRootsModerateStudied for expectorant, antimicrobial, and potential antiparasitic properties; supports the traditional use of elecampane for deep respiratory tract infections.
GermacroneCAS 6902-72-3Zedoary sesquiterpene ketoneTerpenoid (Sesquiterpene)ZedoaryCurcuma zedoariaRhizomeModerateStudied for anti-inflammatory and potential antiviral properties; contributes to the traditional use of zedoary rhizome in digestive and respiratory wellness.
GuaiolCAS 489-86-1Guaiacum sesquiterpene alcoholTerpenoid (Sesquiterpene)GuaiacumGuaiacum officinaleWood / OilModerateStudied for anti-inflammatory and potential antibacterial properties; a naturally occurring sesquiterpene alcohol with historical use in respiratory and joint health preparations.
SESTERTERPENES
Ophiobolin ACAS 4611-05-6Sesterterpenoid; Fungal toxinTerpenoid (Sesterterpene)Brown Spot FungusBipolaris oryzaeFungal CellsEmergingA highly cytotoxic fungal sesterterpene studied in early-stage oncological research for its potential to disrupt cancer cell membrane integrity; extremely toxic, preclinical research only.
ManoalideCAS 76055-64-6Marine sesterterpene; PLA2 inhibitorTerpenoid (Sesterterpene)Marine SpongeLuffariella variabilisWhole OrganismEmergingA potent phospholipase A2 inhibitor from a marine sponge; studied as a molecular template for anti-inflammatory drug development. Not a plant source — included for completeness.
Leucosceptroid AHimalayan Mint sesterterpeneTerpenoid (Sesterterpene)Himalayan MintLeucosceptrum canumLeaf HairsEmergingAn insect-feeding deterrent sesterterpene from Leucosceptrum; studied as a natural pest management compound with early-stage research interest.
DITERPENES
PaclitaxelCAS 33069-62-4Taxol; Bristol-Myers anticancer drugTerpenoid (Diterpene Taxane)Pacific YewTaxus brevifoliaBark / RootsHighA clinically approved microtubule-stabilising chemotherapy agent used for breast, ovarian, lung, and other cancers; one of the most significant plant-derived pharmaceutical discoveries.
Ginkgolide BCAS 15291-77-7BN 52021; Ginkgo PAF antagonistTerpenoid (Diterpene)GinkgoGinkgo bilobaLeaves / SeedsModerateStudied for platelet-activating factor (PAF) antagonism; the primary active ginkgolide contributing to Ginkgo extract's cardiovascular and cognitive-supportive evidence base.
ForskolinCAS 66575-29-9Coleonol; Coleus diterpeneTerpenoid (Diterpene)ColeusColeus forskohliiRootsModerateA potent adenylyl cyclase activator studied for cardiovascular, respiratory, and potential weight management support; used as a pharmacological research tool and in herbal supplements.
Salvinorin ACAS 83729-01-5SalA; Diviner's Sage kappa-agonistTerpenoid (Diterpene)Diviner's SageSalvia divinorumLeavesEmergingA highly potent selective kappa-opioid receptor agonist associated with intense dissociative and perceptual alterations; the first non-nitrogenous compound with potent psychedelic activity. Controlled substance in many jurisdictions.
Abietic AcidCAS 514-10-3Sylvic acid; Rosin acidTerpenoid (Diterpene)PinePinus spp.ResinModerateThe primary resin acid of pine; studied for antimicrobial and anti-inflammatory properties. The main commercial component of rosin used in pharmaceuticals, adhesives, and food coatings.
Carnosic AcidCAS 3650-09-7Rosemary antioxidant diterpeneTerpenoid (Diterpene)RosemaryRosmarinus officinalisLeavesModerateStudied for neuroprotective and antioxidant properties via Nrf2 pathway activation; the primary lipophilic antioxidant of rosemary with potential relevance to cognitive health.
AndrographolideCAS 5508-58-7King of Bitters; AP; Andrographis lactoneTerpenoid (Diterpene Lactone)King of BittersAndrographis paniculataLeavesModerateStudied for antiviral, anti-inflammatory, and immunostimulatory properties; multiple clinical trials support its use for upper respiratory tract infection symptom reduction.
SteviolCAS 471-80-7Steviol diterpene; Stevia aglyconeTerpenoid (Diterpene)SteviaStevia rebaudianaLeavesHighThe diterpene aglycone backbone of steviol glycosides; its glycosylated derivatives are clinically safe, non-caloric sweeteners with established safety profiles and regulatory approval in numerous markets.
CafestolCAS 469-83-0Coffee diterpene; Kahweol companionTerpenoid (Diterpene)CoffeeCoffea arabicaBean (Unfiltered)ModerateStudied for hepatoprotective, antioxidant, and potential cancer chemopreventive properties; also associated with elevated LDL cholesterol when consumed in unfiltered coffee.
KahweolCAS 6894-43-5Coffee diterpene; AntioxidantTerpenoid (Diterpene)CoffeeCoffea arabicaBean (Unfiltered)ModerateStudied alongside cafestol for protective effects on DNA oxidation and potential support for healthy inflammatory balance; imparts similar LDL-elevating effects in unfiltered preparations.
SclareolCAS 515-03-7Clary Sage diterpene diolTerpenoid (Diterpene)Clary SageSalvia sclareaFlowers / LeavesModerateStudied for oestrogenic and potential cytotoxic properties; traditionally used for hormonal balance support. Also a valued fixative in fragrance production.
CarnosolCAS 5957-80-2Rosemary diterpene phenolTerpenoid (Diterpene)RosemaryRosmarinus officinalisLeavesModerateStudied for Nrf2-activating antioxidant, anti-inflammatory, and potential antiproliferative properties; works synergistically with carnosic acid in rosemary preparations.
Tanshinone IIACAS 568-72-9Danshen primary diterpeneTerpenoid (Diterpene)DanshenSalvia miltiorrhizaRootsModerateStudied for cardiovascular protective and anti-inflammatory properties; a key bioactive of Danshen (Red Sage) widely used in Traditional Chinese Medicine and subject to clinical investigation in China.
TRITERPENES & TRITERPENOID SAPONINS
SqualeneCAS 111-02-4Spinacene; Supraene; C30 triterpeneTerpenoid (Triterpene)Olive OilOlea europaeaFruitModerateA triterpene hydrocarbon and precursor to all plant sterols and triterpenoids; studied for skin-moisturising, antioxidant, and potential immune-supportive properties.
GlycyrrhizinCAS 1405-86-3Glycyrrhizic acid; Licorice saponinTerpenoid (Triterpenoid Saponin)LicoriceGlycyrrhiza glabraRootsHighA triterpenoid saponin used clinically in Japan (as glycyrrhizin IV) for chronic hepatitis B and C management; also the primary sweetening compound of licorice root.
Ginsenoside Rb1CAS 41753-43-9Rb1; Ginseng protopanaxadiol saponinTerpenoid (Triterpenoid Saponin)GinsengPanax ginsengRootsModerateThe most abundant ginsenoside; studied for neuroprotective, anti-stress, and metabolic support properties. Part of the evidence base for Panax ginseng as an adaptogen.
Ginsenoside Rg1CAS 22427-39-0Rg1; Ginseng protopanaxatriol saponinTerpenoid (Triterpenoid Saponin)GinsengPanax ginsengRootsModerateStudied for cognitive-supportive and anti-fatigue properties; may promote hippocampal neurogenesis. Contributes to the clinical evidence for ginseng in mental performance.
CelastrolCAS 34157-83-0Tripterine; Thunder God Vine triterpeneTerpenoid (Triterpene)Thunder God VineTripterygium wilfordiiRootsEmergingStudied in early-stage research for potent anti-obesity and anti-inflammatory properties; associated with significant toxicity that limits therapeutic application without delivery formulation.
Asiatic AcidCAS 464-92-6Asiaticoside aglycone; Gotu Kola triterpeneTerpenoid (Triterpene)Gotu KolaCentella asiaticaLeavesModerateStudied for collagen synthesis-stimulating, wound-healing, and neuroprotective properties; supports the evidence base for Centella asiatica in skin repair and cognitive health.
AsiaticosideCAS 16830-15-2Gotu Kola triterpenoid saponinTerpenoid (Triterpenoid Saponin)Gotu KolaCentella asiaticaLeavesModerateThe glycosylated form of asiatic acid; studied for wound healing and venous insufficiency support. The primary bioactive in licensed Centella asiatica wound care preparations.
Ganoderic Acid ACAS 81907-62-2Reishi triterpene; Ganoderma acidTerpenoid (Triterpene)Reishi MushroomGanoderma lucidumFruiting BodyModerateOne of many ganoderic acids studied for immunomodulatory, hepatoprotective, and antihypertensive properties; contributes to the clinical evidence base for Reishi mushroom preparations.
EscinCAS 6805-41-0Aescin; Horse Chestnut saponinTerpenoid (Triterpenoid Saponin)Horse ChestnutAesculus hippocastanumSeedsHighWell-supported by multiple RCTs for chronic venous insufficiency management; strengthens capillary walls and reduces oedema via inhibition of lysosomal enzymes.
Boswellic AcidCAS 631-69-6AKBA; Acetyl-keto-boswellic acid; FrankincenseTerpenoid (Triterpene)FrankincenseBoswellia serrataResinHighA 5-LOX inhibitor with well-documented anti-inflammatory activity; clinical trials support its use for osteoarthritis and inflammatory bowel conditions. Carries EU traditional herbal medicine status.
Corosolic AcidCAS 4547-24-4Banaba triterpene; Anti-diabeticTerpenoid (Triterpene)BanabaLagerstroemia speciosaLeavesModerateStudied for insulin-sensitising and blood glucose-modulating properties; may support healthy postprandial glucose management via glucose transporter activation.
Cucurbitacin ECAS 18444-66-1Cucurbitacin; Bitter Melon triterpeneTerpenoid (Triterpene)Bitter Melon / SquashMomordica charantiaFruit / RootsEmergingA highly bitter defense compound studied for STAT3 and actin cytoskeleton disruption in cancer cell research; associated with significant gastrointestinal irritancy at low doses.
LimoninCAS 1180-71-8Citrus limonoid; Bitter citrus triterpeneTerpenoid (Triterpenoid Limonoid)Lemon / LimeCitrus limonSeedsModerateStudied for antiviral, immune-modulating, and potential anticancer properties; the primary bitterness compound in citrus seeds that reduces on ripening.
DiosgeninCAS 512-04-9Fenugreek steroidal saponin aglyconeTerpenoid (Triterpenoid Saponin)FenugreekTrigonella foenum-graecumSeedsModerateA steroidal saponin aglycone used industrially as a starting material for semi-synthesis of progesterone and other steroid hormones; also studied for direct cholesterol-modulating properties.
LanosterolCAS 79-63-0Biosynthetic sterol precursor; Cataract researchTerpenoid (Triterpene)Lanosulin source / Tea SeedCamellia sinensisSeeds (Oil)EmergingA biosynthetic precursor to all animal and fungal sterols; studied in early-stage research for its potential to reverse protein aggregation in lens cataracts.
NimbinCAS 5945-86-8Neem triterpenoidTerpenoid (Triterpene)NeemAzadirachta indicaSeeds / OilModerateA tetranortriterpenoid studied for insecticidal, antimicrobial, and antifungal properties; contributes to the broad-spectrum biological activity of neem oil preparations.
FriedelinCAS 559-74-0Cork Oak triterpenoidTerpenoid (Triterpene)Cork OakQuercus suberBark / LeavesModerateA pentacyclic triterpenoid studied for anti-inflammatory, analgesic, and hepatoprotective properties; used in traditional medicine for digestive and liver health support.
Betulinic AcidCAS 472-15-13-beta-Hydroxy-lup-20(29)-en-28-oic acidTerpenoid (Triterpene)White BirchBetula pubescensBark / TwigsModerateStudied for selective antiproliferative effects on melanoma cells and potential antiviral properties; of continuing interest in dermatological and oncological research.
LupeolCAS 545-47-1Fagarasterol; Mango triterpeneTerpenoid (Triterpene)Mango / NeemMangifera indicaFruit Pulp / PeelModerateStudied for anti-inflammatory, anti-angiogenic, and skin-protective properties; may contribute to the photoprotective benefits of mango peel polyphenol extracts.
Ursolic AcidCAS 77-52-1Urson; Apple peel triterpeneTerpenoid (Triterpene)Apple / RosemaryMalus domesticaFruit Peel / LeavesModerateStudied for muscle mass preservation, fat metabolism support, and anti-inflammatory properties; of interest in sports nutrition and metabolic health research.
Oleanolic AcidCAS 508-02-1Caryophyllin; Olive triterpeneTerpenoid (Triterpene)Olive TreeOlea europaeaLeavesModerateStudied for hepatoprotective and antimicrobial properties; contributes to the liver-protective activity of olive leaf preparations alongside oleuropein.
PHYTOSTEROLS
Beta-SitosterolCAS 83-46-5beta-Sitosterol; 24-Ethylcholesterol; PhytosterolTerpenoid (Phytosterol)Wheat Germ / NettleTriticum aestivum / Urtica dioicaSeed / RootHighThe most studied phytosterol; competes with cholesterol for intestinal absorption and supports prostate health via 5-alpha-reductase inhibition. Regulatory-approved for cholesterol reduction in food products.
StigmasterolCAS 83-48-7Phytosterol; Soy sterolTerpenoid (Phytosterol)Soybean / Calabar BeanGlycine maxSeedsModerateA plant sterol studied for cholesterol-lowering, anti-inflammatory, and hormone precursor properties; used as a biosynthetic starting material for pharmaceutical steroid production.
CampesterolCAS 474-62-424-Methylcholesterol; Brassica sterolTerpenoid (Phytosterol)Canola / MustardBrassica napusSeedsModerateA phytosterol that may contribute synergistically to healthy cholesterol management when consumed as part of a sterol-rich diet or supplement.
BrassicasterolCAS 474-67-9Rapeseed phytosterol; 22-DehydroergosterolTerpenoid (Phytosterol)RapeseedBrassica napusSeedsModerateA Brassica-specific phytosterol studied for lipid profile management; also used as a chemotaxonomic biomarker for identifying Brassica-derived oils.
SpinasterolCAS 481-18-5Spinach phytosterol; Delta-7-stigmastenolTerpenoid (Phytosterol)SpinachSpinacia oleraceaLeavesModerateA delta-7-phytosterol studied for anti-inflammatory and potential antiulcer properties; a characteristic sterol of spinach and certain other green leafy vegetables.
TETRATERPENES (CAROTENOIDS)
Beta-CaroteneCAS 7235-40-7Provitamin A; beta,beta-Carotene; E160aTerpenoid (Tetraterpene / Carotenoid)Carrot / PumpkinDaucus carotaRoot / FruitHighA provitamin A carotenoid supporting healthy vision and immune function; well-documented antioxidant. Supplemental doses in smokers are associated with increased lung cancer risk — caution warranted.
Alpha-CaroteneCAS 7488-99-5alpha,beta-CaroteneTerpenoid (Tetraterpene / Carotenoid)Carrot / Winter SquashDaucus carotaRoot / PulpModerateA provitamin A carotenoid with lower conversion efficiency than beta-carotene; epidemiological data suggest it may support longevity and healthy cell growth.
LycopeneCAS 502-65-8Psi,psi-Carotene; E160d; Tomato redTerpenoid (Tetraterpene / Carotenoid)Tomato / WatermelonSolanum lycopersicumFruitHighA well-studied antioxidant carotenoid; consistently associated with cardiovascular protection and potential prostate health support in observational studies and some clinical trials.
LuteinCAS 127-40-2Xanthophyll; E161b; Marigold pigmentTerpenoid (Tetraterpene / Carotenoid)Kale / SpinachBrassica oleraceaLeavesHighAccumulates selectively in the macular pigment; well-supported by clinical evidence for reducing risk of age-related macular degeneration and supporting visual function.
ZeaxanthinCAS 144-68-3(3R,3'R)-Zeaxanthin; E161hTerpenoid (Tetraterpene / Carotenoid)Corn / PeppersZea maysSeeds / FruitHighA macular carotenoid studied alongside lutein for visual acuity support and photoprotection of the retina; part of the well-validated AREDS2 supplement evidence base.
AstaxanthinCAS 472-61-7(3S,3'S)-Astaxanthin; Marine carotenoidTerpenoid (Tetraterpene / Carotenoid)Red AlgaeHaematococcus pluvialisWhole CellHighA ketocarotenoid with exceptional antioxidant potency; multiple human trials support its benefits for skin photoprotection, muscle recovery, and eye health.
FucoxanthinCAS 3351-86-8Marine xanthophyll; Brown seaweed pigmentTerpenoid (Tetraterpene / Carotenoid)Brown SeaweedUndaria pinnatifidaFrondsModerateA marine xanthophyll studied for thermogenic fat metabolism-supporting properties; may promote oxidation of white adipose tissue. Limited but emerging human clinical data.
CrocinCAS 42553-65-1Gardenia yellow; Saffron carotenoid diesterTerpenoid (Tetraterpene / Carotenoid)SaffronCrocus sativusFlower StigmaModerateThe primary pigment of saffron; studied for neuroprotective, antidepressant, and cognitive-supportive properties with a growing number of human clinical trials.
NeoxanthinCAS 14646-79-8Xanthophyll; Green leaf carotenoidTerpenoid (Tetraterpene / Carotenoid)SpinachSpinacia oleraceaLeavesModerateAn allenic xanthophyll found in green leafy vegetables; studied for antioxidant activity and potential contributions to carotenoid metabolite diversity in human tissues.
ViolaxanthinCAS 126-29-4Zeaxanthin diepoxide; Pansy pigmentTerpenoid (Tetraterpene / Carotenoid)PansyViola tricolorFlowersModerateAn epoxidised xanthophyll studied for antioxidant and potential antiproliferative properties; converts to zeaxanthin via the xanthophyll cycle in plant chloroplasts.
CapsanthinCAS 465-42-9(3R,3'S,5'R)-Capsanthin; Red pepper pigmentTerpenoid (Tetraterpene / Carotenoid)Paprika / Bell PepperCapsicum annuumFruitModerateThe primary carotenoid pigment of red peppers; studied for HDL-raising and potential antioxidant and anti-inflammatory properties when consumed as part of a varied diet.
BixinCAS 6983-79-5Norbixin precursor; Annatto pigment; E160bTerpenoid (Tetraterpene / Carotenoid)AnnattoBixa orellanaSeed CoatingModerateThe primary orange pigment of annatto; studied for antioxidant and potential photoprotective properties. Widely used as a natural food colourant with an established safety profile.
POLYTERPENES
Natural RubberCAS 9006-04-6Polyisoprene; cis-1,4-Polyisoprene; LatexTerpenoid (Polyterpene)Rubber TreeHevea brasiliensisLatex (Sap)EmergingA high-molecular-weight polyterpene of industrial importance; helps the tree seal wounds by rapid coagulation. Its protein content is the source of latex allergy in sensitised individuals.
Gutta-PerchaCAS 9000-30-0trans-Polyisoprene; Dental polymerTerpenoid (Polyterpene)Gutta-Percha TreePalaquium guttaBark / LeavesHighThe trans-isomer of natural rubber; used clinically as the standard material for endodontic root canal obturation due to its biocompatibility, flexibility, and sealing properties.
ChicleCAS 9000-40-2Natural chewing gum base; Sapodilla latexTerpenoid (Polyterpene)SapodillaManilkara zapotaLatex (Sap)ModerateA polyterpene latex traditionally used as the original chewing gum base; biocompatible and biodegradable, with renewed interest as a natural alternative to synthetic gum bases.
BalataCAS 9006-04-6trans-Polyisoprene; Bulletwood latexTerpenoid (Polyterpene)BulletwoodManilkara bidentataLatex (Sap)EmergingA durable polyterpene historically used for golf ball covers, submarine cable insulation, and industrial belting; studied for biocompatible polymer applications.
ALIPHATIC GLUCOSINOLATES
GlucoraphaninCAS 20830-75-54-Methylsulfinylbutyl glucosinolate; GRNGlucosinolate (Aliphatic)BroccoliBrassica oleraceaFloret / SeedlingHighThe primary glucosinolate of broccoli; enzymatically hydrolysed to sulforaphane by myrosinase on cell disruption. Well-supported by clinical evidence for Nrf2 pathway activation and detoxification enzyme induction.
SinigrinCAS 3952-98-92-Propenyl glucosinolate; Allyl glucosinolateGlucosinolate (Aliphatic)Black MustardBrassica nigraSeedModerateHydrolysed by myrosinase to allyl isothiocyanate, the primary pungent compound of black mustard; studied for antimicrobial, anti-inflammatory, and potential chemopreventive properties.
GlucoerucinCAS 21956-27-64-Methylthiobutyl glucosinolate; GERGlucosinolate (Aliphatic)Arugula (Rocket)Eruca vesicariaLeaf / SeedModerateHydrolysed to erucin, a sulforaphane analogue; studied for antioxidant, anti-inflammatory, and cardiovascular-supportive properties. A major glucosinolate of arugula leaves.
ProgoitrinCAS 585-95-5(2R)-2-Hydroxy-3-butenyl glucosinolateGlucosinolate (Aliphatic)RapeseedBrassica napusSeed / LeafModerateHydrolysed to goitrin, which may inhibit thyroid hormone synthesis at high intake levels; regulated in rapeseed food products. At moderate dietary intake from whole vegetables, risk is generally low.
GluconapinCAS 19253-97-53-Butenyl glucosinolate; GNAGlucosinolate (Aliphatic)Turnip RapeBrassica rapaSeed / LeafModerateHydrolysed to 3-butenyl isothiocyanate; studied for induction of liver phase-II detoxification enzymes supporting healthy xenobiotic metabolism.
GlucobrassicanapinCAS 21292-36-44-Pentenyl glucosinolate; GBNGlucosinolate (Aliphatic)Bok ChoyBrassica rapaLeafModerateHydrolysed to 4-pentenyl isothiocyanate; contributes to the overall glucosinolate-derived detoxification support of Brassica vegetable consumption.
GlucoiberinCAS 534-48-53-Methylsulfinylpropyl glucosinolate; GIBGlucosinolate (Aliphatic)Broccoli / KaleBrassica oleraceaLeaf / FloretModerateHydrolysed to iberin, a sulforaphane congener; studied for Phase-II enzyme-inducing and antioxidant properties contributing to the health benefits of Brassica vegetables.
GlucorapheninCAS 26041-78-74-Methylsulfinyl-3-butenyl glucosinolate; GREGlucosinolate (Aliphatic)RadishRaphanus sativusRootModerateHydrolysed to raphanin; studied for antimicrobial, hepatoprotective, and choleretic properties consistent with the traditional use of radish for liver and gallbladder support.
Glucoalyssin5-Methylsulfinylpentyl glucosinolateGlucosinolate (Aliphatic)Sweet AlyssumLobularia maritimaFlower / LeafEmergingA C5 methylsulfinyl glucosinolate studied for antioxidant and antimicrobial properties in early-stage research; contributes to the glucosinolate diversity of the Brassicaceae family.
Glucocheirolin3-Methylsulfonylpropyl glucosinolateGlucosinolate (Aliphatic)Wallflower / ArugulaCheiranthus cheiriFlower / LeafEmergingA sulfonyl-type aliphatic glucosinolate; studied for cardiovascular and antimicrobial properties as part of the Brassica glucosinolate profile.
GlucocapparinCAS 13433-89-1Methyl glucosinolate; Caper glucosinolateGlucosinolate (Aliphatic)CaperCapparis spinosaFlower Bud / RootModerateThe simplest aliphatic glucosinolate; hydrolysed to methyl isothiocyanate. Studied for hepatoprotective and neuroprotective properties consistent with the traditional Mediterranean use of capers.
Glucoputranjivin(R)-1-Methylethyl glucosinolateGlucosinolate (Aliphatic)PutranjivaPutranjiva roxburghiiLeaf / SeedModerateAn isopropyl glucosinolate studied for anti-inflammatory and antipyretic properties in traditional Ayurvedic medicine contexts.
Glucoiberverin3-Methylthiopropyl glucosinolate; GIVGlucosinolate (Aliphatic)CandytuftIberis amaraSeed / LeafModerateHydrolysed to iberverin; studied for smooth muscle relaxant and antiallergic properties relevant to the traditional digestive use of candytuft preparations.
Glucoberteroin5-Methylthiopentyl glucosinolateGlucosinolate (Aliphatic)Hoary AlyssumBerteroa incanaSeedEmergingA C5 methylthio glucosinolate studied as a botanical pest deterrent; contributes to the structural diversity of the aliphatic glucosinolate sub-class.
Glucocochlearin(S)-1-Methylpropyl glucosinolateGlucosinolate (Aliphatic)Scurvy-grassCochlearia officinalisLeafModerateHydrolysed to a branched-chain isothiocyanate; contributes to the antiscorbutic and antioxidant properties historically attributed to scurvy-grass in traditional seafarer medicine.
GluconapoleiferinCAS 21292-37-52-Hydroxy-4-pentenyl glucosinolate; GNLGlucosinolate (Aliphatic)RutabagaBrassica napusRoot / LeafModerateA hydroxy-alkenyl glucosinolate studied for contributions to healthy blood glucose balance and liver detoxification enzyme support.
Epiprogoitrin(2S)-2-Hydroxy-3-butenyl glucosinolateGlucosinolate (Aliphatic)CrambeCrambe abyssinicaSeedEmergingThe (2S) epimer of progoitrin; studied for plant stress defence roles and as a potential biocontrol compound. Monitored for thyroid-related considerations at high intake.
Dehydroerucin4-Methylthio-3-butenyl glucosinolate; DHEGlucosinolate (Aliphatic)Daikon RadishRaphanus sativusRootEmergingA desaturated glucoerucin congener; studied for antioxidant properties and potential support for respiratory airway clearance.
INDOLIC GLUCOSINOLATES
GlucobrassicinCAS 4356-52-93-Indolylmethyl glucosinolate; I3G; GBSGlucosinolate (Indolic)Brussels SproutsBrassica oleraceaBuds (Sprouts)HighThe most abundant indolic glucosinolate in Brassica vegetables; hydrolysed to indole-3-carbinol (I3C) and subsequently diindolylmethane (DIM), both well-studied for hormone metabolism and chemopreventive support.
4-Hydroxyglucobrassicin4-Hydroxy-I3G; 4-OH-GBSGlucosinolate (Indolic)CabbageBrassica oleraceaLeafModerateHydrolysed to 4-hydroxyindole-3-carbinol; studied for hormonal balance and tissue repair support as part of the indolic glucosinolate family in cabbage.
4-Methoxyglucobrassicin4-Methoxy-I3G; 4-MeO-GBS; NeoglucobrassicinGlucosinolate (Indolic)BroccoliBrassica oleraceaFloretModerateHydrolysed to 4-methoxyindole-3-carbinol; studied for immunomodulatory properties and potential support for healthy cellular surveillance mechanisms.
NeoglucobrassicinCAS 19253-97-51-Methoxy-I3G; N-MeO-GBSGlucosinolate (Indolic)CauliflowerBrassica oleraceaFloretModerateThe N-methoxy derivative of glucobrassicin; studied for anti-inflammatory properties and detoxification pathway activation as part of the Brassica indolic glucosinolate complex.
Glucobrassicin-1-sulfonate1-Sulfo-I3G; Woad indolic GSLGlucosinolate (Indolic)WoadIsatis tinctoriaRoot / LeafModerateFound in woad root, a traditional European blue dye plant; studied for antimicrobial and immunomodulatory properties consistent with the use of Isatis root in traditional Chinese medicine.
AROMATIC GLUCOSINOLATES
GluconasturtiinCAS 499-30-92-Phenylethyl glucosinolate; PEITC precursorGlucosinolate (Aromatic)WatercressNasturtium officinaleLeaf / StemHighHydrolysed to phenethyl isothiocyanate (PEITC); well-studied for Nrf2-activating, DNA-protective, and chemopreventive properties with multiple human bioavailability and intervention trials.
GlucotropaeolinCAS 1119-34-2Benzyl glucosinolate; BITC precursorGlucosinolate (Aromatic)Garden CressLepidium sativumSeed / LeafModerateHydrolysed to benzyl isothiocyanate (BITC); studied for antimicrobial, hepatoprotective, and potential antiproliferative properties. A primary glucosinolate of nasturtium and garden cress.
SinalbinCAS 3952-98-94-Hydroxybenzyl glucosinolate; White Mustard GSLGlucosinolate (Aromatic)White MustardSinapis albaSeedModerateHydrolysed to 4-hydroxybenzyl isothiocyanate, which provides a milder heat than allyl isothiocyanate; studied for antimicrobial and respiratory health-supportive properties.
Glucomoringin4-alpha-L-Rhamnosyloxy-benzyl GSL; GMGGlucosinolate (Aromatic)MoringaMoringa oleiferaLeaf / SeedModerateThe unique glucosinolate of Moringa; hydrolysed by plant myrosinase to the isothiocyanate MIC-1, studied for anti-inflammatory, antioxidant, and immunomodulatory properties.
Glucobarbarin(S)-2-Hydroxy-2-phenylethyl glucosinolateGlucosinolate (Aromatic)Winter CressBarbarea vulgarisLeaf / SeedModerateA hydroxylated aromatic glucosinolate; studied for urinary tract health support and as a marker compound for winter cress. Contributes to insect herbivory resistance.
GlucolepigraminIndanyl glucosinolateGlucosinolate (Aromatic)PepperweedLepidium graminifoliumAerial PartsEmergingA cyclopropane-containing aromatic glucosinolate; studied for antioxidant and antimicrobial properties in early-stage research.
Glucosinojnain4-(alpha-L-Rhamnosyloxy)benzyl GSL; Moringa variantGlucosinolate (Aromatic)MoringaMoringa stenopetalaSeed / LeafModerateA rhamnosyloxy-benzyl glucosinolate from East African Moringa species; studied for anti-inflammatory and circulatory health-supportive properties.
GLUCOSINOLATE HYDROLYSIS PRODUCTS (BIOACTIVE BREAKDOWN COMPOUNDS)
SulforaphaneCAS 4478-93-71-Isothiocyanato-4-(methylsulfinyl)butane; SFN; SFGlucosinolate Hydrolysis Product (Isothiocyanate)BroccoliBrassica oleraceaSprouts / FloretsModerateThe hydrolysis product of glucoraphanin; well-studied for Nrf2 pathway activation and Phase-II detoxification enzyme induction. Requires intact myrosinase activity or gut microbiota for formation from supplements.
Indole-3-CarbinolCAS 700-06-1I3C; Glucobrassicin hydrolysis productGlucosinolate Hydrolysis Product (Indole)Broccoli / CabbageBrassica oleraceaFloret / LeafModerateThe primary hydrolysis product of glucobrassicin; studied for oestrogen metabolism modulation and potential chemopreventive activity. Converts to DIM in the stomach.
DiindolylmethaneCAS 1968-05-4DIM; 3,3'-Diindolylmethane; I3C condensation productGlucosinolate Hydrolysis Product (Indole)Broccoli / CruciferousBrassica oleraceaFloret / LeafModerateFormed from I3C condensation in the acid environment of the stomach; studied for oestrogen receptor modulation and potential support for hormonal balance and immune function.
Phenethyl IsothiocyanateCAS 2257-09-2PEITC; Gluconasturtiin hydrolysis productGlucosinolate Hydrolysis Product (Isothiocyanate)WatercressNasturtium officinaleLeaf / StemModerateThe isothiocyanate from gluconasturtiin hydrolysis; studied for glutathione induction, detoxification support, and potential antiproliferative effects with human bioavailability data available.
Allyl IsothiocyanateCAS 57-06-7AITC; Sinigrin hydrolysis product; Mustard oilGlucosinolate Hydrolysis Product (Isothiocyanate)Black MustardBrassica nigraSeedModerateThe primary hydrolysis product of sinigrin; responsible for the pungency of mustard and wasabi. Studied for antimicrobial, anti-inflammatory, and potential neuroprotective properties.
Iberin3-Methylsulfinylpropyl isothiocyanate; Glucoiberin productGlucosinolate Hydrolysis Product (Isothiocyanate)Kale / BroccoliBrassica oleraceaLeafModerateThe isothiocyanate derived from glucoiberin; studied for Phase-II enzyme-inducing and antioxidant properties contributing to the health value of diverse Brassica vegetable consumption.
ErucinCAS 4430-36-84-Methylthiobutyl isothiocyanate; Glucoerucin productGlucosinolate Hydrolysis Product (Isothiocyanate)ArugulaEruca vesicariaLeafModerateThe sulphide analogue of sulforaphane formed from glucoerucin hydrolysis; studied for comparable Nrf2-activating and antioxidant properties to sulforaphane, with similar bioavailability.
ORGANOSULFUR COMPOUNDS (ALLIUM-DERIVED)
AllicinCAS 539-86-6Diallyl thiosulfinate; Allium bioactiveOrganosulfur (Thiosulfinate)GarlicAllium sativumBulbModerateFormed from alliin by alliinase when garlic tissue is disrupted; studied for antimicrobial, cardiovascular-supportive, and cholesterol-modulating properties. Unstable compound — activity diminishes rapidly with cooking or processing.
AlliinCAS 556-27-4S-Allyl-L-cysteine sulfoxide; Garlic precursorOrganosulfur (Cysteine Sulfoxide)GarlicAllium sativumBulbModerateThe stable precursor to allicin in intact garlic cloves; studied for its own mild cardiovascular and antioxidant properties independent of allicin conversion.
S-AllylcysteineCAS 37921-38-3SAC; Aged Garlic primary activeOrganosulfur (Cysteine Derivative)Aged GarlicAllium sativumBulb (Aged Extract)ModerateThe primary bioactive of aged garlic extract; water-soluble and highly bioavailable. Studied for neuroprotective, cardiovascular, and antioxidant properties with good human pharmacokinetic data.
S-AllylmercaptocysteineSAMC; Aged Garlic organosulfurOrganosulfur (Cysteine Derivative)Aged GarlicAllium sativumBulb (Aged Extract)ModerateA stable water-soluble garlic organosulfur compound studied for potential antiproliferative and hepatoprotective properties alongside SAC in aged garlic preparations.
Diallyl DisulfideCAS 2179-57-9DADS; Garlic oil constituentOrganosulfur (Polysulfide)GarlicAllium sativumBulbModerateA volatile garlic organosulfur compound formed from allicin; studied for antimicrobial, antifungal, and Phase-II enzyme-inducing properties. Responsible for much of the characteristic garlic odour.
Diallyl TrisulfideCAS 2050-87-5DATS; Garlic oil polysulfideOrganosulfur (Polysulfide)GarlicAllium sativumBulbModerateStudied for hydrogen sulfide-generating properties and potential cardioprotective effects via smooth muscle relaxation and vasodilation; the most bioactive of the garlic diallyl polysulfides in preclinical research.
AjoeneCAS 92285-61-5(E,Z)-4,5,9-Trithiadodeca-1,6,11-triene 9-oxideOrganosulfur (Vinyldithiin)GarlicAllium sativumBulbModerateStudied for antiplatelet, antifungal, and potential antiproliferative properties; formed from allicin in aged oil macerates of garlic.
Allyl Methyl DisulfideCAS 2179-58-0AMDS; Garlic breath compoundOrganosulfur (Polysulfide)GarlicAllium sativumBulbEmergingA volatile garlic metabolite contributing to characteristic garlic breath; studied as a marker for garlic organosulfur bioavailability and gut microbial metabolism.
Propyl DisulfideCAS 629-19-6Di-1-propenyl disulfide; Onion organosulfurOrganosulfur (Polysulfide)OnionAllium cepaBulbModerateA primary organosulfur compound of onion; studied for antithrombotic and mild antimicrobial properties. Associated with Heinz body haemolytic anaemia in dogs — not a concern at normal human dietary intake.
CepaenesThiosulfinate esters; Onion tear-factor relatedOrganosulfur (Thiosulfinate)OnionAllium cepaBulbModerateA family of thiosulfinate compounds unique to onion; studied for antiplatelet, anti-inflammatory, and antiasthmatic properties. Thermolabile — activity is reduced by cooking.
IsoalliinCAS 17795-80-1S-(1-Propenyl)-L-cysteine sulfoxide; Onion lachrymatory precursorOrganosulfur (Cysteine Sulfoxide)OnionAllium cepaBulbModerateThe primary cysteine sulfoxide of onion; the precursor to propanethial S-oxide (the lachrymatory factor or tear compound) formed on enzymatic hydrolysis. Studied for antioxidant and antimicrobial properties.
MethiinCAS 3108-60-9S-Methyl-L-cysteine sulfoxide; Brassica organosulfurOrganosulfur (Cysteine Sulfoxide)CabbageBrassica oleraceaLeafModerateA cysteine sulfoxide found in cabbage and other Brassica vegetables; studied for antioxidant and potential hepatoprotective properties as a stable dietary organosulfur source.
Sinigrin Derived AITCCAS 57-06-7Allyl isothiocyanate; Wasabi / Horseradish pungencyOrganosulfur (Isothiocyanate)Horseradish / WasabiArmoracia rusticana / Wasabia japonicaRootModerateThe primary pungency compound of wasabi and horseradish; studied for antimicrobial, anti-inflammatory, and gastric health-supporting properties. Activates TRPA1 channels to produce the characteristic burning sensation.
OTHER NITROGEN-CONTAINING SECONDARY METABOLITES
PiperineCAS 94-62-21-Piperoylpiperidine; Black Pepper amideAlkaloid-related (Amide)Black PepperPiper nigrumDried FruitsHighA well-documented bioavailability enhancer; inhibits CYP3A4 and P-glycoprotein to significantly increase absorption of co-administered bioactives including curcumin and resveratrol.
CapsaicinCAS 404-86-48-Methyl-N-vanillyl-6-nonenamide; VanilloidVanilloid (Capsaicinoid)Chili PepperCapsicum frutescensFruitHighA TRPV1 receptor agonist with well-documented topical analgesic applications; supported by clinical evidence for localised neuropathic and musculoskeletal pain management.
GingerolCAS 23513-14-6[6]-Gingerol; Ginger pungent compoundPhenylpropanoid-related (Shogaol precursor)GingerZingiber officinaleRhizomeHighThe primary pungency compound of fresh ginger; studied extensively for antiemetic, anti-inflammatory, and gastrointestinal comfort-supportive properties. Multiple human trials support its use for nausea management.
ShogaolCAS 555-66-8[6]-Shogaol; Dehydration product of gingerolPhenylpropanoid-relatedDried GingerZingiber officinaleRhizome (Dried)ModerateFormed from gingerol during drying and cooking of ginger; studied for potent anti-inflammatory and potential neuroprotective properties with higher TRPV1 activity than gingerol.
ZingeroneCAS 122-48-5Vanillylacetone; Cooked ginger aromaticPhenylpropanoid-relatedCooked GingerZingiber officinaleRhizome (Cooked)ModerateFormed from gingerol during cooking; studied for anti-inflammatory, antioxidant, and gut health-supportive properties. Contributes to the characteristic aroma of cooked ginger preparations.
Cyanogenic GlycosidesCAS 29883-15-6Amygdalin / Prunasin / Dhurrin (class)Cyanogenic GlycosideBitter Almond / SorghumPrunus amygdalus / Sorghum bicolorSeed / LeafModerateA class of plant defence glycosides hydrolysed to toxic hydrogen cyanide on tissue damage; associated with acute toxicity at high intake. Present at low regulated levels in food-grade bitter almond, cassava, and stone fruit kernels.
AmygdalinCAS 29883-15-6D-Mandelonitrile gentiobioside; Laetrile precursorCyanogenic GlycosideBitter AlmondPrunus amygdalusSeed KernelEmergingA cyanogenic diglycoside that releases hydrogen cyanide on hydrolysis; associated with fatal cyanide poisoning from excessive intake of bitter almond kernels or apricot seeds. Documented for safety reference — not therapeutic.
DhurrinCAS 499-20-7L-Tyrosine-derived CG; Sorghum toxinCyanogenic GlycosideSorghumSorghum bicolorSeedling / LeafEmergingA cyanogenic glycoside that protects young sorghum plants from herbivores; degrades to lower levels in mature grain. Monitored in food sorghum products for cyanide-related safety.
LinamarinCAS 554-35-8Acetone cyanohydrin glucoside; Cassava CGCyanogenic GlycosideCassavaManihot esculentaRootModerateThe primary cyanogenic glycoside of cassava; potentially toxic if cassava is insufficiently processed. Traditional and industrial processing methods (soaking, fermentation, drying) effectively reduce levels to safe dietary thresholds.
STANDARDISED MARKER COMPLEXES — SAPONINS & TRITERPENES
GinsenosidesPanax saponins; Total ginsenosidesTerpenoids (Triterpene Saponin Complex)Korean GinsengPanax ginsengRootHighA complex of Rb1, Rg1, Rd and related saponins; the Rb1 to Rg1 ratio distinguishes Asian from American ginseng.
Notoginsenoside R1CAS 80418-24-2NG-R1Terpenoids (Triterpene Saponin)Tienchi GinsengPanax notoginsengRootModerateThe saponin characteristic of P. notoginseng and the marker distinguishing it from P. ginseng.
AstragalosidesTotal astragalosidesTerpenoids (Cycloartane Triterpene Saponins)AstragalusAstragalus membranaceusRootModerateStandardised as total astragalosides; astragaloside IV is the reference marker and present at low percentage.
Astragaloside IVCAS 84687-43-6AS-IVTerpenoids (Cycloartane Triterpene Saponin)AstragalusAstragalus membranaceusRootModerateThe reference astragalus saponin; poor oral bioavailability constrains the systemic claim.
CycloastragenolCAS 78574-94-4CAG; TA-65 aglyconeTerpenoids (Cycloartane Triterpene)AstragalusAstragalus membranaceusRootEmergingThe astragaloside IV aglycone studied for telomerase activation; human outcome data are minimal.
GypenosidesGynostemma saponinsTerpenoids (Dammarane Triterpene Saponins)JiaogulanGynostemma pentaphyllumAerial PartsModerateDammarane saponins overlapping structurally with the ginsenosides, hence the "southern ginseng" designation.
Saikosaponin ACAS 20736-09-8SSaTerpenoids (Oleanane Triterpene Saponin)BupleurumBupleurum falcatumRootModerateThe principal bupleurum saponin; haemolytic in vitro, so parenteral use is excluded.
BacosidesTotal bacosidesTerpenoids (Dammarane Triterpene Saponin Complex)BrahmiBacopa monnieriWhole PlantHighThe standardisation marker for Bacopa cognitive preparations; assay method strongly affects the declared figure.
Bacoside ABacoside A3 complexTerpenoids (Dammarane Triterpene Saponin)BrahmiBacopa monnieriWhole PlantHighThe defined bacoside fraction used in the better-controlled Bacopa memory trials.
BrahmosideBacopa minor saponinTerpenoids (Triterpene Saponin)BrahmiBacopa monnieriWhole PlantEmergingA minor Bacopa saponin reported to carry CNS activity; not the principal standardisation marker.
CentellosideTECA; Titrated extract of CentellaTerpenoids (Ursane Triterpene Saponin Complex)Gotu KolaCentella asiaticaLeavesModerateThe titrated Centella complex of asiaticoside with asiatic and madecassic acids used in venous and wound trials.
MadecassosideCAS 34540-22-2MadecassolTerpenoids (Ursane Triterpene Saponin)Gotu KolaCentella asiaticaLeavesModerateThe principal Centella saponin in cica skin-repair formulations.
ShatavarinsAsparagus racemosus saponinsTerpenoids (Steroidal Saponins)ShatavariAsparagus racemosusRootEmergingThe shatavari standardisation markers; saponin content varies widely with root age and processing.
Steroidal SaponinsSpirostanol and furostanol saponinsTerpenoids (Steroidal Saponin / Class entry)Various PlantsVariousVariousModerateA class assay rather than a compound; the diosgenin and protodioscin markers are not interchangeable.
ProtodioscinCAS 55056-80-9Furostanol saponinTerpenoids (Furostanol Steroidal Saponin)TribulusTribulus terrestrisAerial PartsEmergingThe Tribulus standardisation marker; content varies by geography and the testosterone claim is unsupported in healthy men.
GuggulsteronesE- and Z-guggulsteroneTerpenoids (Steroid / Pregnane)GuggulCommiphora wightiiOleoresinModerateFarnesoid X receptor antagonists; hepatotoxicity reports in some preparations warrant specification care.
Withanolide ACAS 32911-62-9Withanolide ATerpenoids (Steroidal Lactone)AshwagandhaWithania somniferaRootModerateA defined withanolide used as a root-specific marker; leaf material carries a different withanolide profile.
TriterpenesTotal triterpenesTerpenoids (Triterpene / Class entry)Various PlantsVariousVariousModerateA class assay covering pentacyclic and tetracyclic skeletons with quite different pharmacology.
Total TriterpenesTotal triterpene assayTerpenoids (Triterpene / Class entry)Various PlantsVariousVariousModerateA gravimetric or colorimetric class figure; not comparable with HPLC quantification of named triterpenes.
Arjunolic AcidCAS 4339-72-4Arjunolic acidTerpenoids (Oleanane Triterpene)ArjunaTerminalia arjunaBarkEmergingThe Terminalia arjuna triterpene marker studied for cardiac endpoints in preclinical models.
CucurbitacinCucurbitacins B, D, E, ITerpenoids (Cucurbitane Triterpene)Bitter GourdMomordica charantiaFruitEmergingIntensely bitter cytotoxic triterpenes; toxicity reports follow high-cucurbitacin bottle gourd juice.
CharantinMomordica steroidal glycosideTerpenoids (Steroidal Saponin)Bitter GourdMomordica charantiaFruitEmergingA bitter gourd glycoside studied for glycaemic effects; identity in commercial extracts is poorly defined.
MomordicinMomordicins I and IITerpenoids (Cucurbitane Triterpene)Bitter GourdMomordica charantiaLeavesEmergingBitter cucurbitane triterpenes contributing to the characteristic taste and to glycaemic research interest.
EurycomanoneCAS 84633-29-4Tongkat ali quassinoidTerpenoids (Quassinoid)Tongkat AliEurycoma longifoliaRootEmergingThe Eurycoma standardisation marker; heavy metal contamination has been a recurring issue in this supply chain.
Bitter DiterpenoidsTotal bitter diterpenoidsTerpenoids (Diterpene / Class entry)Various PlantsVariousVariousEmergingA bitterness-weighted class assay rather than a quantification of named compounds.
KutkinPicroliv; Picrosides I and IITerpenoids (Iridoid Glycoside Complex)KutkiPicrorhiza kurroaRhizomeModerateThe hepatoprotective iridoid fraction of Picrorhiza, standardised as picrosides I and II.
AgnusideCAS 11027-63-7AgnusideTerpenoids (Iridoid Glycoside)Chaste TreeVitex agnus-castusFruitModerateThe Vitex standardisation marker; the clinical premenstrual evidence belongs to defined whole extracts.
PaeoniflorinCAS 23180-57-6PaeoniflorinTerpenoids (Monoterpene Glycoside)White PeonyPaeonia lactifloraRootModerateThe principal peony marker, central to the TJ-68 and related traditional formulations.
TanshinonesTanshinone I, IIA, cryptotanshinoneTerpenoids (Abietane Diterpene Quinones)DanshenSalvia miltiorrhizaRootModerateThe lipophilic danshen fraction; the hydrophilic salvianolic acids are a separate standardisation.
Terpene LactonesGinkgolides and bilobalideTerpenoids (Sesquiterpene & Diterpene Lactones)GinkgoGinkgo bilobaLeavesHighStandardised at 6% alongside 24% flavone glycosides in the EGb 761-type specification.
BilobalideCAS 33570-04-6BilobalideTerpenoids (Sesquiterpene Trilactone)GinkgoGinkgo bilobaLeavesHighThe sole sesquiterpene trilactone of the ginkgo terpene fraction; a neuroprotective marker in the standard extract.
AbsinthinCAS 1362-42-1AbsinthinTerpenoids (Guaianolide Sesquiterpene Dimer)WormwoodArtemisia absinthiumAerial PartsEmergingThe intensely bitter wormwood dimer; thujone rather than absinthin is the regulated constituent.
ArtabsinCAS 5956-04-7ArtabsinTerpenoids (Guaianolide Sesquiterpene Lactone)WormwoodArtemisia absinthiumAerial PartsEmergingThe absinthin precursor and a bitter principle of wormwood preparations.
ThymoquinoneCAS 490-91-5TQ; Nigella quinoneTerpenoids (Monoterpenoid Benzoquinone)Black SeedNigella sativaSeedModerateThe black seed oil marker; volatile and light-sensitive, so oil storage conditions determine retention.
ZerumboneCAS 471-05-6ZerumboneTerpenoids (Humulane Sesquiterpene)Shampoo GingerZingiber zerumbetRhizomeEmergingA cross-conjugated sesquiterpene ketone studied for anti-inflammatory and antiproliferative activity.
Valerenic AcidsCAS 3569-10-6Valerenic acid; total valerenic acidsTerpenoids (Sesquiterpenoid Acids)ValerianValeriana officinalisRootModerateThe valerian standardisation marker; the volatile oil and valepotriate fractions are separate specifications.
Patchouli AlcoholCAS 5986-55-0PatchoulolTerpenoids (Sesquiterpene Alcohol)PatchouliPogostemon cablinLeavesEmergingThe principal patchouli oil constituent and its quality marker.
ValenceneCAS 4630-07-3ValenceneTerpenoids (Eudesmane Sesquiterpene)Valencia OrangeCitrus sinensisPeelEmergingA citrus peel sesquiterpene used in flavour and studied for antihistaminic activity.
CedreneCAS 11028-42-5alpha-CedreneTerpenoids (Sesquiterpene Hydrocarbon)CedarwoodJuniperus virginianaHeartwoodEmergingA cedarwood oil sesquiterpene studied for anti-inflammatory and insect-repellent activity.
CedrolCAS 77-53-2CedrolTerpenoids (Sesquiterpene Alcohol)CedarwoodJuniperus virginianaHeartwoodEmergingThe cedarwood oil alcohol marker, studied for sedative and hair-growth endpoints in early work.
CitralCAS 5392-40-5Geranial and neralTerpenoids (Acyclic Monoterpene Aldehyde)LemongrassCymbopogon citratusLeavesModerateThe lemongrass aroma marker; a recognised skin sensitiser requiring fragrance allergen declaration.
EugenolCAS 97-53-04-Allyl-2-methoxyphenolTerpenoids (Phenylpropanoid / Volatile Phenol)CloveSyzygium aromaticumFlower BudHighThe clove oil active with established dental analgesic use; a fragrance allergen requiring declaration.
Terpinen-4-olCAS 562-74-3Terpinen-4-olTerpenoids (Monoterpenol)Tea TreeMelaleuca alternifoliaLeavesHighThe tea tree oil active; the ISO specification sets a minimum for it and a maximum for 1,8-cineole.
GeranylgeraniolCAS 24034-73-9GGOHTerpenoids (Acyclic Diterpene Alcohol)AnnattoBixa orellanaSeedEmergingStudied for statin-associated myopathy and bone endpoints; co-occurs with annatto tocotrienols.
TaxolCAS 33069-62-4PaclitaxelTerpenoids (Taxane Diterpene)Pacific YewTaxus brevifoliaBarkHighA registered cytotoxic pharmaceutical. Informational reference only — not a supplement ingredient and not a sourcing offer.
AzadirachtinCAS 11141-17-6Azadirachtin ATerpenoids (Limonoid)NeemAzadirachta indicaSeed KernelModerateThe neem insect growth regulator and the standardisation marker for agricultural neem preparations.
EmbelinCAS 550-24-3Embelic acidTerpenoids (Benzoquinone)False Black PepperEmbelia ribesFruitEmergingA hydroxybenzoquinone studied for anthelmintic and antifertility activity in traditional use.
STANDARDISED MARKER COMPLEXES — POLYPHENOLS
CurcuminoidsCurcumin, DMC and BDMCPolyphenols (Diarylheptanoid Complex)TurmericCurcuma longaRhizomeHighThe 95% turmeric standardisation; free curcuminoid bioavailability is very low without a delivery system.
TetrahydrocurcuminCAS 36062-04-1THC; reduced curcuminPolyphenols (Reduced Diarylheptanoid)Turmeric (Hydrogenated)Curcuma longaRhizomeEmergingA colourless major curcumin metabolite used where turmeric staining is unacceptable.
SilymarinCAS 65666-07-1Milk thistle flavonolignansPolyphenols (Flavonolignan Complex)Milk ThistleSilybum marianumSeedHighThe silybin, silychristin and silydianin complex; silybin content rather than silymarin weight is the meaningful figure.
HypericinCAS 548-04-9HypericinPolyphenols (Naphthodianthrone)St John’s WortHypericum perforatumFlowering TopsHighThe traditional standardisation marker; a potent CYP3A4 and P-glycoprotein inducer with major drug interactions.
HyperforinCAS 11079-53-1HyperforinPolyphenols (Prenylated Phloroglucinol)St John’s WortHypericum perforatumFlowering TopsHighNow regarded as the principal antidepressant constituent and the main driver of the CYP3A4 induction.
IcariinCAS 489-32-7IcariinPolyphenols (Prenylated Flavonol Glycoside)Horny Goat WeedEpimedium brevicornumAerial PartsModerateThe Epimedium marker and a PDE5 inhibitor in vitro; oral potency is far below pharmaceutical inhibitors.
Alpha-MangostinCAS 6147-11-1alpha-MangostinPolyphenols (Xanthone)MangosteenGarcinia mangostanaPericarpModerateThe principal mangosteen xanthone; the pericarp rather than the edible aril carries it.
XanthonesTotal xanthonesPolyphenols (Xanthone / Class entry)MangosteenGarcinia mangostanaPericarpModerateA class assay for mangosteen pericarp preparations; alpha-mangostin is the reference marker.
Licochalcone ACAS 58749-22-7Licochalcone APolyphenols (Retrochalcone)Chinese LicoriceGlycyrrhiza inflataRootModerateSpecific to G. inflata rather than G. glabra; widely used in anti-blemish skincare.
NeohesperidinCAS 20702-77-6Neohesperidin; NHDC precursorPolyphenols (Flavanone Glycoside)Bitter OrangeCitrus aurantiumPeelModerateThe precursor of the intense sweetener neohesperidin dihydrochalcone.
Citrus BioflavonoidsCitrus bioflavonoid complexPolyphenols (Flavanone Glycoside Complex)CitrusCitrus spp.PeelEmergingColorimetric total-flavonoid assays over-read against HPLC of named compounds; the isolates carry the evidence.
IsoflavonesTotal isoflavonesPolyphenols (Isoflavone / Class entry)Various LegumesVariousSeedEmergingA class assay; soy, red clover and kudzu yield structurally distinct isoflavones that are not interchangeable.
Soy IsoflavonesGenistein, daidzein, glyciteinPolyphenols (Isoflavone Complex)SoybeanGlycine maxGerm or CotyledonEmergingAglycone and glycoside figures differ by roughly 1.6×; germ is daidzein-rich and cotyledon genistein-rich.
Red Clover IsoflavonesBiochanin A and formononetinPolyphenols (Isoflavone Complex)Red CloverTrifolium pratenseAerial PartsEmerging4′-Methylated precursors demethylated in vivo to genistein and daidzein; not a soy substitute.
FlavonoidsTotal flavonoidsPolyphenols (Flavonoid / Class entry)Various PlantsVariousVariousModerateA colorimetric class figure commonly calibrated against rutin; not comparable with named-compound HPLC.
Total FlavonesTotal flavone assayPolyphenols (Flavone / Class entry)Various PlantsVariousVariousModerateA class subset assay; the aluminium chloride method responds to a wide range of phenolics.
Ginkgo Flavone GlycosidesGinkgo-flavonglycosidesPolyphenols (Flavonol Glycoside Complex)GinkgoGinkgo bilobaLeavesHighStandardised at 24% with 6% terpene lactones; ginkgolic acid must be limited below 5 ppm.
AnthocyaninsTotal anthocyaninsPolyphenols (Anthocyanin / Class entry)BilberryVaccinium myrtillusFruitHighA pH-differential class assay; anthocyanin profile rather than total content distinguishes bilberry from other berries.
BetalainsBetanin and betaxanthinsPolyphenols-adjacent (Betalain / Nitrogenous Pigment)BeetrootBeta vulgarisRootModerateNitrogenous pigments, not anthocyanins, and the two do not co-occur in the same plant families.
PolyphenolsTotal polyphenols; GAEPolyphenols (Class entry)Various PlantsVariousVariousModerateA Folin-Ciocalteu class figure expressed as gallic acid equivalents; it responds to non-phenolic reductants too.
TanninsTotal tanninsPolyphenols (Tannin / Class entry)Various PlantsVariousVariousModerateA class assay covering hydrolysable and condensed tannins with quite different chemistry and protein binding.
GallotanninsHydrolysable gallotanninsPolyphenols (Hydrolysable Tannin)Gall OakQuercus infectoriaGallsModerateGalloylglucose-based hydrolysable tannins; distinct from the C-glucosidic ellagitannins of heartwood.
Chebulinic AcidCAS 18942-26-2Chebulinic acidPolyphenols (Hydrolysable Tannin)HaritakiTerminalia chebulaFruitModerateA principal Terminalia chebula tannin and a Triphala standardisation marker.
Stilbene GlycosidesPolydatin; piceidPolyphenols (Stilbene Glycoside)Japanese KnotweedReynoutria japonicaRootModerateThe glycosylated resveratrol precursors; more water-soluble and more stable than the aglycone.
CynarinsCAS 30964-13-7Cynarin; 1,5-dicaffeoylquinic acidPolyphenols (Caffeoylquinic Acid)ArtichokeCynara scolymusLeavesModerateThe artichoke leaf marker; chlorogenic acid content is often reported alongside it.
SalicinCAS 138-52-3SalicinPolyphenols (Phenolic Glycoside)White WillowSalix albaBarkHighMetabolised to salicylic acid; the basis of willow bark preparations and a salicylate-sensitivity caution.
AloinCAS 1415-73-2Barbaloin; aloe-emodin glycosidePolyphenols (Anthraquinone C-Glycoside)Aloe VeraAloe barbadensisLeaf LatexHighA stimulant laxative anthraquinone; regulated and limited in oral aloe preparations.
EleutherosidesEleutheroside B and EPolyphenols (Mixed Glycoside Complex)Siberian GinsengEleutherococcus senticosusRootModerateA heterogeneous marker set — eleutheroside B is a lignan and E a phenylpropanoid, not one class.
MacamidesN-benzyl fatty acid amidesPolyphenols-adjacent (Benzylamide Lipids)MacaLepidium meyeniiRootEmergingMaca-specific benzylamides formed on drying; fresh root contains little, so processing defines the profile.
DNJCAS 19130-96-21-Deoxynojirimycin; DNJAlkaloids (Iminosugar)MulberryMorus albaLeavesModerateAn alpha-glucosidase inhibitor and the mulberry leaf glycaemic marker.
STANDARDISED MARKER COMPLEXES — OTHER CLASSES
AKBACAS 67416-61-93-O-Acetyl-11-keto-beta-boswellic acidTerpenoids (Pentacyclic Triterpene Acid)Indian FrankincenseBoswellia serrataOleoresinModerateThe most potent 5-lipoxygenase-inhibiting boswellic acid; present at low percentage in total boswellic acid.
Gymnemic AcidsTotal gymnemic acidsTerpenoids (Oleanane Triterpene Saponins)GurmarGymnema sylvestreLeavesModerateSuppress sweet taste perception on contact; the glycaemic evidence is modest and mostly from small trials.
CapsaicinoidsCapsaicin and dihydrocapsaicinAlkaloids (Vanillylamide / Class entry)ChilliCapsicum annuumFruitHighTRPV1 agonists quantified in Scoville units or by HPLC; capsaicin and dihydrocapsaicin dominate the total.
CalystegineCalystegines A, B, CAlkaloids (Nortropane / Polyhydroxy)PotatoSolanum tuberosumTuberEmergingPolyhydroxylated nortropane glycosidase inhibitors present in several common Solanaceae foods.
4-HydroxyisoleucineCAS 781658-23-14-HO-IleAlkaloids-adjacent (Non-protein Amino Acid)FenugreekTrigonella foenum-graecumSeedModerateAn insulinotropic non-protein amino acid and the fenugreek glycaemic marker.
5-HydroxytryptophanCAS 4350-09-85-HTP; oxitriptanAlkaloids-adjacent (Non-protein Amino Acid)GriffoniaGriffonia simplicifoliaSeedModerateBypasses the rate-limiting tryptophan hydroxylation, so it is more potent per milligram and carries serotonin syndrome caution.
CordycepinCAS 73-03-03′-DeoxyadenosineNucleosides (Purine / Deoxy)CordycepsCordyceps militarisFruiting BodyModerateThe Cordyceps militaris marker; C. sinensis material contains little, which distinguishes the two species.
BakuchiolCAS 10309-37-2BakuchiolTerpenoids (Meroterpene Phenol)BabchiPsoralea corylifoliaSeedModerateA retinol-functional-analogue in skincare; psoralen content must be limited for phototoxicity.
SaponinsTotal saponinsTerpenoids (Saponin / Class entry)Various PlantsVariousVariousModerateA foam-index or gravimetric class figure; triterpene and steroidal saponins differ fundamentally in pharmacology.
GlucosinolatesTotal glucosinolatesGlucosinolates (Class entry)BroccoliBrassica oleraceaSeed & SproutHighInactive until myrosinase hydrolysis; sulforaphane yield rather than glucosinolate content is the functional figure.
Beta-Glucans(1→3),(1→4)- and (1→3),(1→6)-beta-glucanCarbohydrates (Polysaccharide / Class entry)Oat and MushroomAvena sativaGrain & Fruiting BodyHighTwo distinct linkage classes sharing a name: cereal acts by viscosity, fungal through Dectin-1 recognition.
SteviosideCAS 57817-89-7SteviosideTerpenoids (Steviol Glycoside)SteviaStevia rebaudianaLeavesHighThe original steviol glycoside; more bitter in the aftertaste than rebaudioside A.
Rebaudioside ACAS 58543-16-1Reb ATerpenoids (Steviol Glycoside)SteviaStevia rebaudianaLeavesHighThe cleanest-tasting of the abundant steviol glycosides and the usual target of stevia purification.
Steviol GlycosidesTotal steviol glycosides; E960Terpenoids (Steviol Glycoside / Class entry)SteviaStevia rebaudianaLeavesHighRegulated as a class with a total steviol-equivalent basis; individual glycosides differ in taste profile.
LignanPlant lignans; SDGPolyphenols (Phenylpropanoid Dimer / Class entry)FlaxLinum usitatissimumHullModerateConverted by gut microbiota to enterolignans; conversion capacity varies substantially between individuals.
Beta-EcdysteroneCAS 5289-74-720-Hydroxyecdysone; 20ETerpenoids (Phytoecdysteroid)CyanotisCyanotis spp.RootEmergingOne unreplicated RCT, and the same work found marketed product content far off label. On the WADA Monitoring Programme since 2020.
Natural CaffeineCAS 58-08-2Caffeine from botanical sourceAlkaloids (Purine Methylxanthine)Green CoffeeCoffea arabicaBeanHighMolecularly identical to synthetic caffeine, so carbon isotope ratio is the only authentication.