Quercetin Powder 98%

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Product Overview

Quercetin 98% Powder — Sophora japonica is a highly purified flavonoid isolate standardised to NLT 98% quercetin content by HPLC, sourced primarily from the flower buds of Sophora japonica (Japanese Pagoda Tree) — the most commercially significant botanical source for pharmaceutical and supplement-grade quercetin production. Quercetin is one of the most abundant dietary flavonoids and one of the most extensively studied polyphenols in the biomedical literature, with documented activity across immune modulation, cardiovascular support, antioxidant pathways, and — most recently — senolytic and longevity-related research. At 98% purity, this is the specification required for label claims, clinical dose matching, and incoming QC verification in cGMP supplement manufacturing.

Grade: Pharmaceutical and supplement grade. HPLC-verified NLT 98% quercetin per lot. Suitable for capsule, tablet, sachet, and liposomal formulation.

Shelf-life: 24–36 months when stored below 25 °C (<60% RH) in a tightly sealed, opaque container away from direct light and moisture.

Form: Fine yellow-green powder. The characteristic yellow pigmentation is intrinsic to the quercetin flavonoid structure — not an additive.

Process: Solvent extraction from Sophora japonica flower buds, followed by purification and crystallisation to NLT 98% quercetin by HPLC.

Note on forms: Quercetin is available as anhydrous (quercetin base) or dihydrate (quercetin·2H₂O) forms. The dihydrate contains approximately 90% quercetin by weight due to water of crystallisation — confirm which form is specified on your CoA when calculating active dose per serving.

Wholesale supply: Available from 250 g sample to multi-kilogram bulk. CoA and SDS supplied with every order. Contact us for bulk pricing.

CoA Grade Data
Parameter Specification Result Method
Note: These values represent our universal baseline specifications. Your batch-specific Certificate of Analysis (CoA) is available upon request or provided with shipment.
Physical Properties
Particle Size 60 - 80 Mesh NLT 95% USP <786>
Appearance / Colour Characteristic of source material Conforms Visual
Odour Characteristic of source material Conforms Organoleptic
Moisture / Loss on Drying (LOD) NMT 5% Conforms USP <731>
Bulk Density 0.3 – 0.8 g/mL (typical) Conforms USP <616>
Heavy Metals Profile
Total Heavy Metals NMT 10 ppm Conforms AAS – ICP-MS
Lead (Pb) NMT 3.0 ppm Conforms AAS – ICP-MS
Arsenic (As) NMT 2.0 ppm Conforms AAS – ICP-MS
Cadmium (Cd) NMT 1.0 ppm Conforms AAS – ICP-MS
Mercury (Hg) NMT 0.5 ppm Conforms AAS – ICP-MS
Microbiological Analysis
Total Plate Count NMT 10,000 Cfu/gm Conforms APHA CHP 7, FDA BAM
Yeast & Mold Counts NMT 1,000 Cfu/gm Conforms 7th Ed
E. coli Absent Absent AOAC 991.14
Salmonella Absent Absent AOAC 991.14
Pseudomonas aeruginosa Absent Absent AOAC 991.14
Staphylococcus aureus Absent Absent AOAC 991.14
Extended Testing — Bulk Orders (25 kg+)
Aluminium (Al) NMT 1.0 ppm Available on request ICP-MS
Barium (Ba) NMT 1.0 ppm Available on request ICP-MS
Nickel (Ni) NMT 1.0 ppm Available on request ICP-MS
Nanoparticles (inorganic) Absence of engineered nanoparticles Available on request TEM / DLS
*Note: The values above represent our universal baseline specifications. Please correlate final results with your batch-specific Certificate of Analysis (COA) provided upon shipment.

*Legend: NLT = Not less than | NMT = Not more than | Cfu = Colony forming unit / gram

Product QnA

Q: What is the difference between quercetin anhydrous and quercetin dihydrate, and which should I specify?

A: Quercetin dihydrate contains two water molecules in its crystal lattice — approximately 10% of total weight. A 500 mg capsule of quercetin dihydrate delivers approximately 440 mg of quercetin equivalent. Most commercial quercetin at supplement grade is the dihydrate form — more stable under ambient storage than anhydrous. For label claims stating a specific quercetin dose, confirm the form on the CoA and calculate dose weight accordingly. Specify which form you require at enquiry stage. Claim strength: High

Q: How significant is quercetin's bioavailability problem and what are the options?

A: Standard quercetin aglycone has 1–17% oral bioavailability — highly variable depending on food matrix and individual gut microbiome. Co-administration with fat significantly improves absorption. For more predictable bioavailability, quercetin phytosome (phospholipid complex) is the evidence-supported option — up to 20× improved bioavailability vs standard quercetin in human pharmacokinetic data. For most supplement formulations, standard 98% taken with a fat-containing meal is adequate and cost-effective. Claim strength: High

Q: What is the evidence for the quercetin-zinc immune combination?

A: Quercetin has been proposed as a zinc ionophore — facilitating intracellular zinc transport where zinc exerts antiviral and immune-regulatory effects. The mechanism is demonstrated in cell culture. The combination has a biologically plausible rationale, strong consumer recognition, and reasonable safety profile. Pair with zinc bisglycinate or zinc citrate at 10–25 mg elemental zinc per serving. Direct human clinical evidence for the specific combination remains at the emerging stage — the mechanistic rationale is stronger than the direct clinical data. Claim strength: Moderate

Q: Can I make a senolytic claim for quercetin on a supplement label?

A: Not directly — "senolytic" as a term exceeds current structure-function claim thresholds in the US and EU and would require substantiation beyond what is currently approved. The appropriate framing is "supports healthy ageing" or "supports cellular health." The senolytic mechanism is credible and commercially valuable as educational background content — blog posts, product education, and science pages — rather than a direct label claim. Position the science, not the term. Claim strength: Moderate

Claim-strength scale – High = multiple human studies; Moderate = a few trials; Emerging = early lab data.

 

Shipping & Returns

Priority International Air Shipping (5–8 Days)

  • 250g – 500g: Fixed at $20 – $25
  • 1kg – 2kg: Fixed at $27 – $32
  • Bulk 5kg Tiers: Capped at $49 Max

Domestic Shipping: 3–4 business days; International shipping:5–8 business days.

Return window: 30 days from the date of delivery

Herbuno is not responsible for products restricted or requiring special clearance in your country. Please check with your local customs office to ensure your order can be imported without permits or prescriptions.

Please read our Shipping & Refund policy for full details.

 

Customer Support

Our customer support team is here to help! Reach us at hello@herbuno.com or WhatsApp us at +91-8638692590.

We’re available Monday to Friday, 10am–7pm EST, and Saturday to Sunday, 1pm–6pm EST.

If you contact us outside these hours, we’ll get back to you as soon as we’re online. Your satisfaction is our priority!

 

Nutritional Details

Typical values Per 100g

Quercetin (NLT by HPLC), 98 g
Moisture (NMT), 5 g
Total ash (NMT), 5 g
Sodium, <50 mg
Heavy metals, Within USP/EP limits per lot CoA

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This product is derived from natural sources, and slight variations in color, aroma, texture, or appearance may occur between batches due to seasonal differences in the raw materials or changes in supplier. These natural variations do not affect the product’s quality or efficacy.

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Capsule Formulation

Standard dose is 500–1,000 mg per day in one to two servings. A single 500 mg HPMC capsule is the standard format — quercetin 98% fills well at this dose weight. Confirm anhydrous vs dihydrate form at specification stage — the dihydrate contains approximately 10% water of crystallisation, meaning 500 mg dihydrate delivers approximately 440 mg quercetin equivalent. Adjust dose weight accordingly for label accuracy.

Beverage & Functional Food

Standard quercetin 98% has very low water solubility — direct addition to aqueous beverages produces visible settling. For clear beverage applications, specify quercetin phytosome or cyclodextrin inclusion complex instead. For solid food matrices (bars, fortified powders), standard 98% integrates appropriately. Note the yellow-green pigmentation contribution at higher inclusion rates.

End Use

500 mg once daily with a meal containing dietary fat — absorption improves significantly in the presence of lipids. Generally well tolerated; headache and mild GI discomfort occasionally reported at higher doses. Space 90 minutes from medications — particularly blood pressure medications and anticoagulants — as a routine precaution.

Stacking

The quercetin-zinc-Vitamin C combination is the most established immune-support stack in the natural supplement market. Bromelain has been studied for improving quercetin absorption — the quercetin-bromelain-Vitamin C three-way combination is a commercially proven format. Introduce one variable at a time.

Broad-spectrum antioxidant activity: Quercetin's flavonoid structure enables direct free radical scavenging, metal chelation, and upregulation of endogenous antioxidant enzymes — SOD, catalase, and glutathione peroxidase. This antioxidant mechanism underpins several of quercetin's downstream effects across immune, cardiovascular, and anti-inflammatory pathways.

Immune modulation via mast cell inhibition: Quercetin inhibits mast cell degranulation and histamine release — the basis for its positioning in immune and allergy-support formulations. The effect is well-documented in vitro and in animal models; human evidence for seasonal allergy symptom reduction is emerging with increasing consistency across trials.

Cardiovascular support — blood pressure and LDL oxidation: Multiple human studies have documented modest but consistent blood pressure reduction with daily quercetin supplementation. Quercetin also inhibits LDL oxidation — a key step in atherosclerotic plaque formation — and supports endothelial nitric oxide production. One of the more evidence-supported cardiovascular claims available for a dietary flavonoid.

Senolytic activity — longevity positioning with a distinct mechanistic rationale: Quercetin has been identified as a senolytic agent — selectively clearing senescent cells that accumulate with ageing and drive chronic inflammation. This positions quercetin in the growing healthy ageing category with a mechanism substantively different from general antioxidant claims. Label framing should use "supports healthy ageing" rather than "senolytic" — the latter exceeds current regulatory thresholds in most markets.

Serving Size: 500 mg (supplement use, with meal containing dietary fat); as specified in formulation SOP (manufacturing use)

Ingredients: Quercetin 98% Powder (Sophora japonica flower bud, solvent-extracted and purified)

Does Not Contain: Added sugar, starch fillers, artificial additives, preservatives, colouring agents

Allergen Information: Vegan. Gluten-free. Soy-free. Dairy-free. Tree nut-free. No known allergens at standard supplement doses. Individuals taking blood pressure medications, anticoagulants, or immunosuppressants should consult a healthcare professional before use.

Usage Recommendation: 500 mg once daily with a meal containing dietary fat. Space approximately 90 minutes from medications as a routine precaution. Not for use during pregnancy without medical advice.

Storage: Store in a tightly sealed, opaque container below 25 °C (<60% RH), in a cool, dry, dark location. Protect from moisture and direct light.

Keep Away From Children

Scientific name: Sophora japonica L. (syn. Styphnolobium japonicum) — primary commercial source. Quercetin is also present in Allium cepa (onion), Camellia sinensis (green tea), and various other food plants, but Sophora japonica flower buds are the primary source for pharmaceutical-grade isolation at commercial scale.

Botanical source & part: Japanese Pagoda Tree — flower buds (pre-bloom), solvent-extracted and purified to quercetin NLT 98% by HPLC.

Common names: Quercetin (English) · Quercetin dihydrate (English, hydrate form) · Sophora flower extract (English) · Huái Huā Mǐ — 槐花米 (Huái Huā Mǐ — Mandarin, referring to the source flower bud)

Other regional names (with transliteration): German — Quercetin · French — Quercétine · Spanish — Quercetina · Japanese — Kuerusechin (クエルセチン) · Arabic — Kwirsitiin (كيرسيتين) · Hindi — Kvarseetin (क्वार्सेटिन)

Country of origin: India

Intended use

Raw bulk ingredient for use by qualified formulators, manufacturers, and researchers. Not a finished dietary supplement or therapeutic product.

Regulatory status

Not evaluated by the FDA, EFSA, or any other regulatory authority. Finished products must comply with all applicable local regulations, labelling requirements, and safety assessments prior to sale.

Medical advice

Information on this page is for technical reference only. It does not constitute medical advice and is not intended to diagnose, treat, cure, or prevent any disease or health condition.

Buyer responsibility

Inclusion levels, claims, and applications vary by formulation context and target market. The buyer is solely responsible for regulatory compliance of any finished formulation.

Safe handling

Follow applicable local regulations for food, cosmetic, or supplement applications. Consult a qualified regulatory advisor where required. Keep away from children. Store as directed on the CoA.

Herbuno.com is operated by Gausyn Global LLP (India). We do not provide medical advice or prescriptions. Please consult a qualified healthcare professional before use.

Collapsible content

How to store?

Keep it in a cool and dry place away from moisture and sunlight. Store the contents in an airtight Container after opening the package.

Where do we ship?

DOMESTIC (India):

We deliver across all postal codes in India.

INTERNATIONAL (Export) :

We export and ship to almost all countries in the world.

Popular markets are United States, United Kingdom (UK), Canada, China, Australia, France, Germany, Italy, Netherland, Switzerland, Belgium, Austria, Finland, Sweden, Norway, Poland, Denmark, Lithuania, Serbia, Slovakia, Croatia, Greece, Kuwait, Israel, UAE, Singapore, Indonesia, Malaysia, Thailand, Vietnam, South Korea, Japan, Canada, Nepal, Bangladesh, Sri Lanka

Is delivery free?

International Shipping is charged based on destination and total weight. You will be shown the shipping cost at checkout.

What payment methods do you accept?

We accept all major credit/debit cards, UPI, net banking, PayPal and international cards. Cash on Delivery (COD) is currently not available.

Do you offer private label options?

Yes, we do! We work with select partners on private label and bulk supply arrangements. If you're looking to sell our products under your own brand or source in bulk, email us at hello@herbuno.com with your requirements.