HerbIQ - Verbindungen

Sparteine (Quinolizidine Alkaloid · Antiarrhythmic · Uterotonic · CYP2D6 Probe)

Compound Sparteine (Lupinidine) Chemical class Alkaloid — Quinolizidine (Tetracyclic lupane-type) CAS 90-39-1 Primary source Cytisus scoparius (Scotch broom / common broom), Lupinus spp. (lupins) Key applications Sodium/potassium channel blocker, antiarrhythmic...

Sparteine (Quinolizidine Alkaloid · Antiarrhythmic · Uterotonic · CYP2D6 Probe)

Compound Sparteine (Lupinidine) Chemical class Alkaloid — Quinolizidine (Tetracyclic lupane-type) CAS 90-39-1 Primary source Cytisus scoparius (Scotch broom / common broom), Lupinus spp. (lupins) Key applications Sodium/potassium channel blocker, antiarrhythmic...

Symphytine (Comfrey Pyrrolizidine Alkaloid · Topical Context · PA Regulatory Reference)

Compound Symphytine Chemical class Alkaloid — Pyrrolizidine Alkaloid (Unsaturated macrocyclic PA; from comfrey) CAS 22257-23-4 Primary source Symphytum officinale (comfrey), Symphytum asperum (rough comfrey) Key applications Informational reference — primary...

Symphytine (Comfrey Pyrrolizidine Alkaloid · Topical Context · PA Regulatory Reference)

Compound Symphytine Chemical class Alkaloid — Pyrrolizidine Alkaloid (Unsaturated macrocyclic PA; from comfrey) CAS 22257-23-4 Primary source Symphytum officinale (comfrey), Symphytum asperum (rough comfrey) Key applications Informational reference — primary...

Monocrotaline (Pyrrolizidine Alkaloid · PAH Research Model · Pulmonary Toxin · Informational)

Compound Monocrotaline Chemical class Alkaloid — Pyrrolizidine Alkaloid (Macrocyclic unsaturated PA; pulmonary and hepatic toxin) CAS 315-22-0 Primary source Crotalaria spectabilis (showy crotalaria, rattlebox), Crotalaria species Key applications Informational reference...

Monocrotaline (Pyrrolizidine Alkaloid · PAH Research Model · Pulmonary Toxin · Informational)

Compound Monocrotaline Chemical class Alkaloid — Pyrrolizidine Alkaloid (Macrocyclic unsaturated PA; pulmonary and hepatic toxin) CAS 315-22-0 Primary source Crotalaria spectabilis (showy crotalaria, rattlebox), Crotalaria species Key applications Informational reference...

Senecionine (Pyrrolizidine Alkaloid · Hepatotoxic · HVOD · Regulatory Reference)

Compound Senecionine Chemical class Alkaloid — Pyrrolizidine Alkaloid (Unsaturated macrocyclic PA; hepatotoxic) CAS 130-01-8 Primary source Senecio jacobaea (ragwort / tansy ragwort), Senecio vulgaris, multiple Senecio species Key applications Informational...

Senecionine (Pyrrolizidine Alkaloid · Hepatotoxic · HVOD · Regulatory Reference)

Compound Senecionine Chemical class Alkaloid — Pyrrolizidine Alkaloid (Unsaturated macrocyclic PA; hepatotoxic) CAS 130-01-8 Primary source Senecio jacobaea (ragwort / tansy ragwort), Senecio vulgaris, multiple Senecio species Key applications Informational...

Veratramine (Veratrum Steroidal Alkaloid · Historical Antihypertensive · Informational)

Compound Veratramine Chemical class Alkaloid — Steroidal Alkaloid (Jervanine-type; non-teratogenic reduced form) CAS 60-70-8 Primary source Veratrum viride (American false hellebore), Veratrum album, Veratrum californicum Key applications Informational reference —...

Veratramine (Veratrum Steroidal Alkaloid · Historical Antihypertensive · Informational)

Compound Veratramine Chemical class Alkaloid — Steroidal Alkaloid (Jervanine-type; non-teratogenic reduced form) CAS 60-70-8 Primary source Veratrum viride (American false hellebore), Veratrum album, Veratrum californicum Key applications Informational reference —...

Jervine (Veratrum Steroidal Alkaloid · Primary Teratogen · Hedgehog Pathway · Informational)

Compound Jervine Chemical class Alkaloid — Steroidal Alkaloid (Jervanine-type; 11-ketone Veratrum alkaloid) CAS 469-59-0 Primary source Veratrum californicum (California corn lily), Veratrum album (white hellebore) Key applications Informational reference —...

Jervine (Veratrum Steroidal Alkaloid · Primary Teratogen · Hedgehog Pathway · Informational)

Compound Jervine Chemical class Alkaloid — Steroidal Alkaloid (Jervanine-type; 11-ketone Veratrum alkaloid) CAS 469-59-0 Primary source Veratrum californicum (California corn lily), Veratrum album (white hellebore) Key applications Informational reference —...

Cyclopamine (Veratrum Steroidal Alkaloid · Hedgehog Pathway · SMO Inhibitor · Teratogen)

Compound Cyclopamine (11-Deoxojervine) Chemical class Alkaloid — Steroidal Alkaloid (Jervanine-type; Veratrum isosteroidal) CAS 4449-51-8 Primary source Veratrum californicum (California corn lily, false hellebore) Key applications Hedgehog signalling pathway inhibitor (oncology...

Cyclopamine (Veratrum Steroidal Alkaloid · Hedgehog Pathway · SMO Inhibitor · Teratogen)

Compound Cyclopamine (11-Deoxojervine) Chemical class Alkaloid — Steroidal Alkaloid (Jervanine-type; Veratrum isosteroidal) CAS 4449-51-8 Primary source Veratrum californicum (California corn lily, false hellebore) Key applications Hedgehog signalling pathway inhibitor (oncology...

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